WorldCat Identities

Demmy, Todd L.

Overview
Works: 6 works in 12 publications in 1 language and 632 library holdings
Roles: Editor, Author
Publication Timeline
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Most widely held works by Todd L Demmy
Video-assisted thoracic surgery (VATS) by Todd L Demmy( )

4 editions published in 2001 in English and Undetermined and held by 613 WorldCat member libraries worldwide

Lung surgery complications: prevention and management( Book )

4 editions published in 2006 in English and held by 12 WorldCat member libraries worldwide

Surgical oncology update for medical oncologists( Book )

1 edition published in 2007 in English and held by 3 WorldCat member libraries worldwide

Surgical oncology update for medical oncologists( )

1 edition published in 2007 in English and held by 2 WorldCat member libraries worldwide

Video-Assisted Thoracic Surgery by Todd L Demmy( )

1 edition published in 2001 in English and held by 1 WorldCat member library worldwide

Video-assisted thoracic surgery (VATS) or thoracoscopy has been applied to almost every organ system within the chest. Frequently, confusion has arisen regarding the appropriate application of this technology and the preparation needed to provide it to patients. Pertinent topics for discussion are preoperative imaging/localization, anesthesia/airway management patient positioning, video/assistant positioning, special supplies, and postoperative care. The purpose of this book is to provide a framework based on these and other issues to share helpful technical tips, assist operating room personn
Original Articles: Non–Small Cell Lung Cancer - A Phase I Study of Light Dose for Photodynamic Therapy Using 2-[1-Hexyloxyethyl]-2 Devinyl Pyropheophorbide-a for the Treatment of Non–Small Cell Carcinoma In Situ or Non–Small Cell Microinvasive Bronchogenic Carcinoma: A Dose Ranging Study( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

ABSTRACT: : Introduction: : We report a phase I trial of photodynamic therapy (PDT) of carcinoma in situ (CIS) and microinvasive cancer (MIC) of the central airways with the photosensitizer (PS) 2‐[1‐hexyloxyethyl]‐2‐devinyl pyropheophorbide‐a (HPPH). HPPH has the advantage of minimal general phototoxicity over the commonly used photosensitizer porfimer sodium (Photofrin; Pinnacle Biologics, Chicago, IL). Methods: : The objectives of this study were (1) to determine the maximally tolerated light dose at a fixed photosensitizer dose and (2) to gain initial insight into the effectiveness of this treatment approach. Seventeen patients with 21 CIS/MIC lesions were treated with HPPH with light dose escalation starting from 75 J/cm 2 and increasing to 85, 95, 125, and 150 J/cm, 2 respectively. Follow‐up bronchoscopy for response assessment was performed at 1 and 6 months, respectively. Results: : The rate of pathological complete response (CR) was 82.4% (14 of 17 evaluable lesions; 14 patients) at 1 month and 72.7% (8/11 evaluable lesions; 8 patients) at 6 months. Only four patients developed mild skin erythema. One of the three patients in the 150 J/cm 2 light dose group experienced a serious adverse event. This patient had respiratory distress caused by mucus plugging, which precipitated cardiac ischemia. Two additional patients treated subsequently at this light dose had no adverse events. The sixth patient in this dose group was not recruited and the study was terminated because of delays in HPPH supply. However, given the observed serious adverse event, it is recommended that the light dose does not exceed 125 J/cm 2 . Conclusions: : PDT with HPPH can be safely used for the treatment of CIS/MIC of the airways, with potential effectiveness comparable to that reported for porfimer sodium in earlier studies
 
Audience Level
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Audience Level
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  Kids General Special  
Audience level: 0.02 (from 0.00 for Video-assi ... to 0.94 for Surgical o ...)

Video-assisted thoracic surgery (VATS)
Covers
Lung surgery complications: prevention and management
Languages
English (11)