WorldCat Identities

Hardin, Charles

Works: 3 works in 17 publications in 1 language and 305 library holdings
Genres: Handbooks, manuals, etc  Outlines, syllabi, etc 
Roles: Editor
Classifications: QH442.2, 572.8
Publication Timeline
Publications about  Charles Hardin Publications about Charles Hardin
Publications by  Charles Hardin Publications by Charles Hardin
Most widely held works by Charles Hardin
Cloning, gene expression, and protein purification : experimental procedures and process rationale ( Book )
9 editions published in 2001 in English and held by 240 WorldCat member libraries worldwide
Biochemistry : essential concepts by Charles Hardin ( Book )
7 editions published between 2012 and 2013 in English and held by 64 WorldCat member libraries worldwide
"One-semester biochemistry courses are notorious for overwhelming students with the magnitude of material covered in their texts and lectures. Biochemistry: Essential Concepts distills the basic ideas covered in a one-semester course without the extraneous details that burden most texts. Authors Charles Hardin and James Knopp demonstrate the core concepts of biochemistry--including cell biology, amino acids, metabolism, and DNA--in a variety of real-world contexts. With the last forty percent of the text devoted to review questions and practice tests, Biochemistry: Essential Concepts equips students for success in the one-semester biochemistry course and prepares them for their future studies and careers."--Publisher's website
Stabilization of Z-RNA under Physiological Conditions and Recognition by Anti-Z DNA Antibodies ( Book )
1 edition published in 1987 in English and held by 1 WorldCat member library worldwide
Radioimmunoassay and nitrocellulose filter-binding competition experiments were performed to determine the extent of recognition of Bromine-poly(r(C-G) by anti-Z-DNA antibodies. The polyclonal rabbit anti-Br-poly(d(C-G)igG preparations T4 and Z6 specifically recognize the Z-form of polyR(C-G, although the binding affinities are 10-to 100fold lower for Z-RNA than for various forms of Z-DNA. Competition RIA experiments verify the presence of a Z-DNA like determinant in left handed Br poly R(C-G) at physiological Sodium Chloride concentration. Phosphate buffer or high ionic strength conditions inhibit recognition of Z-RNA by anti Z-DNA IgGs, consistent with recognition of a phosphodiester backbone determinant. In summary, these spectroscopic and immunochemical studies demonstrate that under conditions of conformational stress (i.e. containing brominated nucleosides) left-handed Z-RNA is stable and is specifically recognized by proteins at physiological temperature and ionic strength
Audience Level
Audience Level
  Kids General Special  
Audience level: 0.65 (from 0.00 for Stabilizat ... to 0.73 for Biochemist ...)
Alternative Names
Hardin, Charles.
Hardin, Charles C.
English (17)