WorldCat Identities

Bashir, Khurram

Overview
Works: 7 works in 13 publications in 2 languages and 125 library holdings
Genres: Handbooks and manuals  Academic theses 
Roles: Author
Classifications: RC377, 616.834
Publication Timeline
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Most widely held works by Khurram Bashir
Handbook of multiple sclerosis by Khurram Bashir( Book )

7 editions published between 2001 and 2002 in English and held by 114 WorldCat member libraries worldwide

Pediatric practice by Paul R Carney( )

1 edition published in 2011 in English and held by 7 WorldCat member libraries worldwide

A Complete "Visual Atlas" for Critical-Care Treatments
Characterization of a rice Mitochondrial Iron Transporter (OsMIT) by Khurram Bashir( )

1 edition published in 2009 in Undetermined and held by 1 WorldCat member library worldwide

Mitochondrial iron (Fe) homeostasis is important for various cellular processes including heme synthesis and Fe-S cluster synthesis, however the proteins involved in mitochondrial Fe uptake and homeostasis has not been characterized in plants. We have cloned and characterized a putative Mitochondrial Iron Transporter in rice (OsMIT). OsMIT was identified by T-DNA knockout mutant screening as a member of mitochondrial substrate carrier family and is homologous to yeast mitochondrial Fe transporters MRS3 and MRS4. OsMIT is located on rice chromosome 3 and encodes a predicted polypeptide of 329 amino acids. OsMIT-GFP protein, when expressed in tobacco BY-2 cells, was localized to the mitochondria. Yeast mrs3mrs4 double knockout mutants were used to investigate the role of OsMIT. Overexpression of OsMIT in yeast complemented the growth defect of yeast strain mrs3mrs4 under conditions of limiting Fe confirming that OsMIT plays a role in mitochondrial Fe homeostasis. Moreover, the mrs3mrs4 yeast strain expressing OsMIT accumulated comparable levels of Fe to WT in contrast to vector control which accumulated high Fe compared to WT. These results suggested that OsMIT is a mitochondrial protein involved in Fe homeostasis. The characterization of OsMIT will provide the chances to increase our understanding about mitochondrial Fe homeostasis and enable us to develop strategies to mitigate Fe deficiency stress in plants
Duo fa xing ying hua shou ce( Book )

1 edition published in 2003 in Chinese and held by 1 WorldCat member library worldwide

Ben shu fen ba ge bu fen, Fen bie jie shao le ren lei tuo sui qiao ji bing de qian jing he fen lei, MS de li shi hui gu, MS de liu xing bing xue, Shi yan xing bian tai fan ying xing nao ji sui yan he MS de bing li he bing li ji zhi, MS de lin chuang zheng zhuang he ti zheng deng nei rong
Characterization of a mitochondrial iron regulated gene (MIR) in rice by Khurram Bashir( )

1 edition published in 2009 in Undetermined and held by 1 WorldCat member library worldwide

Mitochondria utilize iron (Fe), but the proteins involved in mitochondrial Fe regulation have not been characterized in plants. We cloned and characterized a mitochondrial iron-regulated (MIR) gene that is involved in Fe homeostasis in rice. MIR expressed in tobacco BY-2 cells was localized to the mitochondria. MIR transcription was significantly increased in response to Fe deficiency in the roots and shoots. MIR is not homologous to any known protein, as no homologs were found in the rice or Arabidopsis genome databases, or in the EST database for other organisms. Growth in the MIR T-DNA knock-out rice mutant (mir) was significantly impaired compared with wild-type (WT) plants, under both Fe-sufficient and Fe-deficient conditions. Furthermore, Fe accumulation in shoots and roots of mir plants was more than twice that in WT plants, under both Fe-sufficient and Fe-deficient conditions. Despite the high accumulation of Fe in roots and shoots, Fe deficiency-inducible genes were expressed in mir plants, indicating that mir may not be able to utilize the Fe for physiological functions. These results suggest that MIR is a rice-specific mitochondrial protein that plays a significant role in Fe homeostasis
 
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Audience level: 0.55 (from 0.54 for Handbook o ... to 0.99 for Characteri ...)

Handbook of multiple sclerosis
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