WorldCat Identities

Buck, William B.

Works: 18 works in 29 publications in 2 languages and 100 library holdings
Genres: Handbooks and manuals  Biography  Case studies 
Roles: Author
Publication Timeline
Most widely held works about William B Buck
Most widely held works by William B Buck
Natural poisons in horses by Jeffery O Hall( Book )

4 editions published between 1993 and 1995 in English and held by 40 WorldCat member libraries worldwide

This text is presented as a basic guide to horse owners for the identification and understanding of some of the most common, natural poisons affecting horses. It discusses the most common problems caused by plants and molds. Naturally occurring poisons of concern for a horse owner can vary greatly with geographic location
Household pets as monitors of lead exposure to humans by William B Buck( Book )

2 editions published in 1994 in English and held by 19 WorldCat member libraries worldwide

Toxicología veterinaria clínica y diagnóstica by William B Buck( Book )

4 editions published in 1981 in Spanish and held by 18 WorldCat member libraries worldwide

Conceptos y toxicologia basica; Toxicos relacionados con los anlimentos, con la industria; Toxicolos de natureza vegetal; Antihelminticos; Farmacos antibacterianos; Fungicidas; Herbicidas; Inseticidas; Molusquicidas; Rodenticidas; Biotoxinas; Metales y metaloides; Gases toxicos (amoniaco, dioxido de carbono, monoxido de carbono, acido sulfhidrico, dioxido de nitrogene, oxidos de azufre); Compuestos quimicos varios: corrosivos (acidos, alcalis, fenoles) e alquitran de carbon, fenol
Lead poisoning in domestic animals by L. C Anderson( Visual )

3 editions published in 1976 in English and held by 5 WorldCat member libraries worldwide

Outlines the potential sources of lead poisoning and reviews the biochemical mechanisms involved. Includes an analysis of clinical signs and differential diagnosis as well as post-mort examination. Prevention and treatment are also discussed
Toxicologic and Analytical Studies with T-2 and Related Trichothecene Mycotoxins( )

3 editions published between 1983 and 1985 in English and held by 3 WorldCat member libraries worldwide

T-2 toxin intravascularly produced a cardiovascular shock syndrome in swine characterized by early decreased cardiac output and urine production, and a later decline in blood pressure. Core body temperature remained normal but extremities became cold. Hemoglobin of arterial blood was oxygen saturated in spite of cutaneous cyanosis. Severe metabolic acidosis developed. There were marked elevations in plasma 6-keto-PGF1alpha, and thromboxane B2 (metabolites of vasoactive prostanoids), and transitory elevations in epinephrine and norepinephrine. Serum calcium and glucose declined while phosphorus, BUN, magnesium and potassium increased. Pathologic changes included lymphoid necrosis, gastroenteric mucosal hyperemia, enterocyte necrosis, focal myocardial degeneration and endocardial hemorrhage. A gas chromatographic-electron capture detection method for the analysis of T-2 toxin and metabolites in plasma and urine has been developed. Isolates of Fusarium have been obtained and are being screened for trichothecene profiles. In vitro incubations of T-2 toxin with swine liver microsomes has resulted in the production of several new metabolites
Water deprivation - sodium ion toxicity by William B Buck( Visual )

1 edition published in 1972 in English and held by 2 WorldCat member libraries worldwide

Examines water deprivation sodium ion toxicity, a common problem in swine that is caused by limited water intake. Illustrates the clinical signs, mechanism of action, and pathologic changes of this condition and covers differential diagnosis and therapeutic measures
The barefoot professor : ...any footprints? The saga of an Ozark hillbilly lad becoming a university professor by William B Buck( Book )

1 edition published in 2013 in English and held by 2 WorldCat member libraries worldwide

The role of gastrointestinal microflora in the metabolism and toxicity of trichothecene mycotoxins by Steven Philip Swanson( )

1 edition published in 1988 in English and held by 1 WorldCat member library worldwide

Physiological and biochemical changes in serially sampled cerebrospinal fluid and blood during induced convulsions in sheep by William B Buck( )

1 edition published in 1963 in English and held by 1 WorldCat member library worldwide

Effects of copper and selenium on antibody response, weight gains and blood parameters in beef calves grazing high or low endophyte (acremonium coenophialum) tall fescue (festuca arundinaceae, schrep) by Larry Joseph Thompson( )

1 edition published in 1996 in English and held by 1 WorldCat member library worldwide

Parenteral Se and/or Cu was used to supplement growing beef calves (age 7 months) marginally deficient in these two trace elements and pastured on high-endophyte (HE) or low-endophyte (LE) tall fescue. The 64 calves were randomly assigned to one of eight treatment groups (HE or LE, supplemented or non-supplemented Cu, supplemented or non-supplemented Se) and pastured for an 84-day study period during summer months, 4 animals on each of 16 paddocks (8 HE = over 85% infestation, 8 LE = under 20% infestation) 2.024 hectares in area. Parameters included weight gain, whole blood Se concentration, serum Cu concentration, trichloroacetic acid-precipitated serum Cu concentration (TCA-Cu), serum clinical chemistries, hematological evaluations, and serum antibody response (IgG and IgM) to a synthetic antigen, TGAL, as measured by ELISA. There was no difference between treatment groups in initial weights, blood Se, serum Cu, TCA-Cu, and baseline serum ELISA values. A significant effect of endophyte level was noted (p =.0001) with HE decreasing weight gain versus LE. A positive treatment effect on weight gain was noted (p =.0204) with the (Cu + Se)-supplemented animals having the highest average daily gain. The combination of Cu + Se resulted in a higher serum Cu than Cu-supplementation alone (p =.0286). Calves on HE had lower serum Cu and TCA-Cu than calves on LE (p =.0002, p =.0001, respectively). Calves on HE had decreases in Ca (p =.0015), glucose (p =.0018), serum gamma-glutamyl transpeptidase (GGT) activity (p =.0207), hematocrit (p =.0001), hemoglobin (p =.0001), phosphorus (p =.001), and total protein (p =.0118) and increases in creatinine (p =.0095) versus calves on LE although all values remained within normal physiological limits. Trace element treatment effects were noted for Ca (p =.0001) and hematocrit (p =.0037) with supplemented animals having higher serum Ca and hematocrit. Administration of TGAL resulted in a rise in serum IgG and IgM, as evidenced by increases in ELISA absorbance units. Calves on HE had decreased IgG response (p =.0009) and decreased IgM response (p =.0004) versus calves on LE. Calves supplemented with Cu, Se, or Cu + Se had increased IgM response over controls. Results of this study indicate that pasturing of growing beef calves on HE decreased serum Cu and TCA-Cu as compared with calves on LE, but blood Se was unaffected. The supplementation with parenteral Cu and/or Se decreased the adverse effects of HE on weight gain of calves marginally deficient in Cu and Se, with the supplementation of both Cu and Se being most effective. Calves pastured on HE have decreased antibody response to TGAL versus calves pastured on LE. Supplementation of Cu and/or Se improved the blood concentrations of these trace elements and improved the IgM antibody response
Bromethalin-based rodenticides : mode of action, toxicity, clinical effects, and treatment efficacy in rats, dogs, and cats by David Christopher Dorman( )

1 edition published in 1990 in English and held by 1 WorldCat member library worldwide

The purpose of these studies was to define the toxicity of bromethalin-based rodenticides, develop treatments, and determine new modes of action of bromethalin. Bromethalin-based rodenticides are highly neurotoxic to cats (bait LD$sb{50}$ 0.54 mg bromethalin/kg) and dogs (bait LD$sb{50}$ 3.56 mg bromethalin/kg). Bromethalin poisoning in the dog and cat produced a dose dependent delayed toxic syndrome. Sublethal doses of bromethalin to dogs and cats resulted in delayed CNS depression, hindlimb ataxia, paresis, and paralysis. Higher doses given to dogs resulted in rapid severe muscle tremors and generalized seizures. Bromethalin toxicosis was also associated with increased cerebrospinal fluid pressure and cerebral edema. Bromethalin toxicosis produces acute and chronic EEG changes. Predominant abnormal EEG changes included: spike and spike-and-wave EEG patterns; high voltage slow wave activity; photoconvulsive or photoparoxysmal irritative responses, and marked voltage depression. Histologic lesions included diffuse white matter spongiosis, mild microgliosis, and optic nerve vacuolization. Ultramicroscopic examination of brainstem revealed occasional swollen axons, intramyelenic vacuolization, and myelin splitting at the intraperiod line. Bromethalin was detected in kidney, liver, fat, and brain tissues using gas chromatography with electron capture detection. Bromethalin caused increased feline hepatic cytochrome P-450 and cytochrome b$sb5$ concentrations and decreased microsomal aminopyrine N-demethylase and 4-nitrophenetole-O-deethylase activities. Repeated oral administration of a superactivated charcoal/sorbitol (SAC) product was an effective therapy for bromethalin toxicosis in the dog. The administration of combined mannitol/dexamethasone were ineffective therapies in dogs or cats given lethal bromethalin doses. Delayed administration of SAC was ineffective in bromethalin-dosed cats. Extract of Gingko biloba (EGB) given (100 mg/kg) to adult male Sprague-Daley rats immediately after bromethalin (1.0 mg/kg) administration was associated with a decreases in clinical sign severity, brain malonaldehyde concentration, brain % water, and brain sodium concentration. Bromethalin binding to cytochrome P-450 was associated with a modified Type II binding spectrum that had a peak at 420 nm and a trough at 390 nm. Hepatic cytochrome P-450 from the microsomal fractions isolated from cats given bromethalin had a similar difference spectrum (peak at 420 nm, trough at 390 nm) when compared to control cat cytochrome P-450
Characterization and therapeutic alteration of the biliary excretion and enterohepatic cycling of zearalenone in sexually immature swine by Michael LeRoy Biehl( )

1 edition published in 1989 in English and held by 1 WorldCat member library worldwide

The purposes of these studies were to characterize the biliary excretion and enterohepatic cycling (EHC) of zearlenone (ZEN) in young pigs and to therapeutically mimic the effect of bile removal in enhancing body clearance of ZEN. ($sp3$H) ZEN was administered intravenously (IV), orally, and intravenously with bile removal (IVB) to female, 10-to 14-week-old pigs. The biological half life of total plasma radioactivity in IV and orally dosed pigs (86.6 hrs.) was much greater than that of IVB pigs (3.34 hrs.). Secondary peaks in plasma metabolite concentrations were seen during the terminal elimination phase in IV and oral animals and metabolites were still detectable at 48 hrs. postdosing. In IVB pigs, these peaks were absent, relative metabolite profiles were altered and ZEN and metabolites were no longer detectable after 16 hrs. Biliary recovery of radioactivity, principally as glucuronide conjugates was extensive (45.61 $pm$ 4.73%) and significantly greater than that of fecal recovery in IV (6.56 $pm$ 0.78%) or oral (21.74 $pm$ 1.56%) pigs. Absorption of ZEN from the intestinal tract was estimated to be 80-85%. Intraduodenal administration of bile containing ($sp3$H) ZEN and glucuronide metabolites resulted in recovery of 64.5 $pm$ 4.89% of the dose in bile, 20.78 $pm$ 3.94% in urine, and the presence of glucuronide conjugates of ZEN and $alpha$-zearalenol (ZEL) in portal and jugular plasma. Evidence for metabolism of ZEN by the intestinal mucosa was present. A pharmacokinetic compartmental model for the disposition of intravenously administered ZEN and metabolites in swine is proposed. The mean terminal elimination rate and corresponding biological half life for ZEN in IV pigs was 0.03 hr$sp{-1}$ and 28.97 hrs., respectively, and for IVB pigs 0.24 hr$sp{-1}$ and 2.94 hrs. In another study, oral superactivated charcoal (SAC) altered the disposition of ($sp3$H) ZEN in swine in a manner similar to total bile removal (EHC interrupted). Glucuronide conjugates were not detectable in plasma after 12 hours with either treatment and fecal recovery of radioactivity in pigs given SAC (30.2 $pm$ 9.6%) was similar to biliary recovery (32.3 $pm$ 12.0%) in the other treatment group. 15% dietary alfalfa did not appear to have a significant overall effect. The above findings indicate that biliary excretion and EHC are major factors influencing the disposition of ZEN in pigs and that oral SAC may be therapeutically effective in altering the EHC process
The effect of soils parameters on the bioavailability and retention of lead in rats by Phyllis B Malpas( )

1 edition published in 1996 in English and held by 1 WorldCat member library worldwide

This study investigated the relationship between soil cation exchange capacity (CEC) and soil amendments (lime and phosphate) to the retention of lead in soil fed to rats. This study also related the amount of lead that can be extracted from in situ contaminated soils from a secondary smelter site to both soil properties and to the tissue lead concentrations in rats. In a six week feeding trial, 208 rats were divided into 26 groups and fed diets containing contaminated and uncontaminated soils (5% of diet) of three CEC levels that were amended with lime and/or phosphate or unamended. A soil-free negative control and lead acetate positive control group were included. Lead concentrations were measured in blood, liver, kidney, and femur. There were no significant amendment effects in the low lead soils, although there was a small CEC effect. The high lead soil groups showed no CEC effect; however, amendment type was significant and consistent across the tissues, with the lime and phosphate/lime groups generally being lower than the unamended and phosphate-amended groups. However, the total lead had more influence on the tissue values than the amendment effects. A third soil concentration (220-250 mg/kg) that did not fit into the low soil groups (40-50 mg/kg) showed a significant amendment effect for week 3 and 6 blood and femur. The extraction studies used 4 extractants: HNO$sb3$, EDTA, ammonium acetate (1N) and the Bray P-1 (PA) solution (0.03 M NH$sb4$F in 0.025 M HCl). The results of these studies indicated that all of the extractable lead concentrations were well correlated with total lead, but the ammonium acetate and the PA extractants were able to extract a slightly greater amount of lead from the low CEC than the high CEC soil. The conclusions were that sorption (CEC) effects were more notable at low lead concentrations, and solubility effects had more influence at high lead concentrations. However, the overriding effect on the bioavailability of lead to rats, in this study, was the total amount of lead in the soil
Warfarin and Pindone Poisoning in the Dog and Cat by William B Buck( Visual )

1 edition published in 1972 in English and held by 1 WorldCat member library worldwide

Discusses the Anticoagulant Rodenticides Containing Coumanins and Pivalyl. The Mechanism of Action Is Presented Graphically, With Film Documentation of Clinical Signs and Post Mortem Examination. Methods of Treatment Are Discussed
Diagnosis and Management of Trichothecene in the Swine Model( )

1 edition published in 1988 in English and held by 1 WorldCat member library worldwide

The efficacy of a variety of approaches for the treatment of iv induced acute T-2 toxicosis was assessed in rats and swine. (1) Oral (po) (superactivated charcoal (SAC), intravenous (iv), dexamethasone (DEX), intraperitoneal (ip), methylpredenisolone (MPSS), but not ip ascorbic acid, were effective post-toxin therapeutic agents in rats as measured by increases in survival times (ST). (2) Pre- and post-toxin (iv) treatment of rats with po SAC resulted in increased ST and decreased lesion severity in the duodenum, jejunum, and ileum. (3) SAC or Ambersorb resin XE-348F was effective in absorbing T-2 toxin vitro, and in prolonging the STs of rats given lethal (8 mg/kg) po doses of the toxin followed by po SAC or resin at 1 g/kg or less. SAC was a more effective binding agent than the resin. (4) Similarities in pharmacokinetic data for DEX in rats indicated that they may be an acceptable model for humans. Keywords: T-2 Toxin, Therapy, Cutaneous therapy, Combination therapy, Drug therapy, Metabolism, Gl Blood flow, Superactivated charcoal, Pathophysiology, Histopathology, Ascorbic acid, Dexamethasone, Dexamethasone pharmackinetics, Methylprednisolone, Ambersorb resin, Diactoxyscirpenol, Dexoynivalenol, Biotransformation, De-epoxidation, Analysis, Hydrolysis, Hydroxylation, Conjugation, Mass spectra, Metabolism
Effect of therapeutic intervention of pathophysiology, pathology, and survival in rats and swine following acute intravenous exposure to t-2 toxin by Robert Howard Poppenga( )

1 edition published in 1987 in English and held by 1 WorldCat member library worldwide

Epidemiology of lead poisoning in cattle : a summary of 63 episodes of lead poisoning in cattle studied during the five-year period 1965-1970 by William B Buck( Book )

1 edition published in 1970 in English and held by 1 WorldCat member library worldwide

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Audience level: 0.64 (from 0.48 for Epidemiolo ... to 0.99 for Toxicologi ...)