WorldCat Identities

Schraermeyer, Ulrich

Overview
Works: 14 works in 17 publications in 2 languages and 56 library holdings
Roles: Author, dgs, Editor, Contributor, Other
Classifications: RE9334, 617.7
Publication Timeline
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Most widely held works by Ulrich Schraermeyer
An improved method for the isolation and culture of retinal pigment epithelial cells from adult rats by Analena Elisabeth Langenfeld( )

1 edition published in 2018 in English and held by 13 WorldCat member libraries worldwide

Innate immunity of the eye( Book )

1 edition published in 2013 in English and held by 11 WorldCat member libraries worldwide

The effects of a single intravitreal injection of the VEGF-A-inhibitors aflibercept and ranibizumab on glomeruli of monkeys by Sarah Christner( )

1 edition published in 2017 in English and held by 4 WorldCat member libraries worldwide

Effects of intravitreally injected Fc fragment on rat eyes by Tatjana Taubitz( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

A new method for ultrastructural localization of lipid peroxides in the eye Vorstellung einer neuen Methode* by Ulrich Schraermeyer( )

1 edition published in 1998 in English and held by 2 WorldCat member libraries worldwide

The effects of VEGF-A-inhibitors aflibercept and ranibizumab on the ciliary body and iris of monkeys by Maximilian Ludinsky( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Investigation of pathomechanisms and treatment safety of age-related and juvenile macular degeneration by Tatjana Taubitz( )

1 edition published in 2020 in English and held by 2 WorldCat member libraries worldwide

Elemental mapping of Neuromelanin organelles of human Substantia Nigra: correlative ultrastructural and chemical analysis by analytical transmission electron microscopy and nano-secondary ion mass spectrometry( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Abstract: Neuromelanin (NM) is a compound which highly accumulates mainly in catecholamine neurons of the substantia nigra (SN), and is contained in organelles (NM-containing organelles) with lipid bodies and proteins. These neurons selectively degenerate in Parkinson's disease and NM can play either a protective or toxic role. NM-containing organelles of SN were investigated by Analytical Electron Microscopy (AEM) and Nano-Secondary Ion Mass Spectrometry (NanoSIMS) within human tissue sections with respect to ultrastructure and elemental composition. Within the NM-containing organelle, the single NM granules and lipid bodies had sizes of about 200-600 nm. Energy-Dispersive X-ray microanalysis spectra of the NM granules and lipid bodies were acquired with 100 nm beam diameter in AEM, NanoSIMS yielded elemental maps with a lateral resolution of about 150 nm. AEM yielded the quantitative elemental composition of NM granules and bound metals, e.g., iron with a mole fraction of about 0.15 atomic percent. Chemical analyses by AEM and NanoSIMS were consistent at the subcellular level so that nanoSIMS measurements have been quantitated. In NM granules of SN from healthy subjects, a significant amount of S, Fe, and Cu was found. In lipid bodies an amount of P consistent with the presence of phospholipids was measured. The improved detection limits of nanoSIMS offer new possibilities for chemical mapping, high-sensitivity trace element detection, and reduced acquisition times. Variations between individual NM granules can now be investigated effectively and quantitatively by NanoSIMS mapping Cu and Fe. This should yield new insight into the changes in chemical composition of NM pigments during healthy aging and disease. Neuromelanin-containing organelles of dopamine neurons in normal human substantia nigra were investigated by analytical electron mircoscopy and secondary ion mass spectroscopy (NanoSIMS) yielding the ultrastructure and elemental composition. In neuromelanin granules a significant amount of S, Fe and Cu was found. In lipid bodies an amount of P consistent with the presence of phospholipids was measured. The improved sensitivity of NanoSIMS shows differences in chemical composition between individual neuromelanin granules and allows to study chemical changes of neuromelanin organelles during aging and disease. Abstract : Neuromelanin-containing organelles of dopamine neurons in normal human substantia nigra were investigated by analytical electron mircoscopy and secondary ion mass spectroscopy (NanoSIMS) yielding the ultrastructure and elemental composition. In neuromelanin granules a significant amount of S, Fe and Cu was found. In lipid bodies an amount of P consistent with the presence of phospholipids was measured. The improved sensitivity of NanoSIMS shows differences in chemical composition between individual neuromelanin granules and allows to study chemical changes of neuromelanin organelles during aging and disease
Intussusceptive Vascular Remodeling Precedes Pathological Neovascularization by Zaheer Ali( )

1 edition published in 2019 in English and held by 1 WorldCat member library worldwide

Die Bildung von Melanin und Ommochrom in Augen von Vertebraten und Arthropoden by Ulrich Schraermeyer( Book )

1 edition published in 1999 in German and held by 1 WorldCat member library worldwide

A retinal model of cerebral malaria by François Paquet-Durand( )

1 edition published in 2019 in English and held by 0 WorldCat member libraries worldwide

 
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Audience level: 0.88 (from 0.69 for Innate imm ... to 1.00 for Innate imm ...)

Languages
English (11)

German (6)