WorldCat Identities

Kreek, Mary Jeanne

Works: 19 works in 23 publications in 2 languages and 149 library holdings
Genres: Popular works  Academic theses 
Roles: Other, Editor, Author, Contributor
Classifications: QH437, 611.01816
Publication Timeline
Most widely held works by Mary Jeanne Kreek
Dual addiction : pharmacological issues in the treatment of concomitant alcoholism and drug abuse( Book )

5 editions published in 1984 in English and held by 119 WorldCat member libraries worldwide

Alcoholism and drug addiction in pregnancy by Enoch Gordis( Book )

1 edition published in 1977 in English and held by 8 WorldCat member libraries worldwide

Blockade of alcohol escalation and "relapse" drinking by pharmacological FAAH inhibition in male and female C57BL/6J mice by Yan Zhou( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

Neurocognitive and neuroinflammatory correlates of PDYN and OPRK1 mRNA expression in the anterior cingulate in postmortem brain of HIV-infected subjects by Vadim Yuferov( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

Female Sex Steroids and Cholestasis( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

Matrix-Assisted Laser Desorption Mass Spectrometry of Biotransformation Products of Dynorphin A in Vitro by James Z Chou( )

1 edition published in 1994 in English and held by 2 WorldCat member libraries worldwide

Welcome to the genome : a user's guide to the genetic past, present, and future by Rob DeSalle( Book )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

"Welcome to the Genome takes you right into the thick of today's most cutting-edge science and its far-reaching implications. Authors Rob DeSalle and Michael Yudell have written a book which clearly explains the ongoing saga of our attempts to understand the mystery of biology's Rosetta Stone and use its code to better our lives." "This book employs an understandable style and full-color illustrations to provide insights into the complex science involved. It delves into the past discoveries that led to the sequencing of the human genome; it presents the challenges facing today's scientists and society and culture in general; and it considers the future possibilities of the developing genome era. Social issues, particularly questions of ethics, receive special attention, covering an important area too often overshadowed by science and technology."--Jacket
Scientists of tomorrow( Visual )

1 edition published in 2004 in English and held by 1 WorldCat member library worldwide

Lynn Poole gives the statistics of U.S. graduates in science and predicts the numbers through 1961, noting that a growing supply of competent scientists is critical. He discusses "juvenile delinquents" and suggests that a constructive way to guide them is through the Science Talent Search. In order to qualify, student contestants must submit answers to an examination measuring their science aptitude, a record of their grades, personal data by their teachers, and a 1,000-word project report. In the thirteenth annual Talent Search for Westinghouse Science Scholarships, 32 boys and 8 girls throughout the United States received a trip to Washington, D.C. to compete for final scholarships. Photos show some finalists during their trip visiting such scientific sites as the Bureau of Standards, the Department of Terrestrial Magnetism, the National Institutes of Health, and the Naval Ordnance Lab. In the studio, $400 scholarship winners Mary Jeanne Kreek, of Woodrow Wilson High School in Washington, D.C., explains her project on allergies, and Victor A. Schmidt, of Milford Mill High School in Baltimore County, demonstrates his planetarium project. The program concludes with photos of a random selection of the other forty winners and their projects
Effects of mesyl salvinorin B alone and in combination with naltrexone on alcohol deprivation effect in male and female mice( )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

Highlights: Mesyl Salvinorin B (MSB) reduced alcohol "relapse" in male and female mice. Naltrexone reduced alcohol "relapse" in male and female mice. Synergistic blockade of alcohol "relapse" by a combination of MSB and naltrexone. Abstract: Alcohol relapse plays a major role in alcohol dependence and is an important focus for the treatment of alcoholism. The alcohol deprivation effect (ADE) is a widely used paradigm in rodents to model the relapse episodes that occur in human alcoholics. Mesyl Salvinorin B (MSB) is a potent and selective kappa opioid receptor (KOP-r) full agonist, with fewer side effects (e.g ., sedation or anhedonia) than classic KOP-r full agonists and a longer duration of action in mice than the structurally similar salvinorin A. We have recently found that MSB prevents cocaine seeking in a rat self-administration model and reduces excessive alcohol drinking in a mouse escalation model via a KOP-r-mediated mechanism. Here, we further investigated whether MSB alone (0.3-3mg/kg) or in combination with naltrexone (mu-opioid receptor antagonist at 1mg/kg) altered alcohol "relapse" drinking using a mouse ADE paradigm. Both male and female mice, exposed to 3-week intermittent access alcohol drinking in a two-bottle choice paradigm with 24-h access every other day, developed excessive alcohol intake and then displayed pronounced ADE after 1-week abstinence. Acute administration of MSB prevented the ADE at 3mg/kg in both male and female mice. Upon investigation of potential synergistic effects between naltrexone and MSB, we found that acute administration of a combination of MSB (0.3mg/kg) and naltrexone (1mg/kg) reduced the ADE at doses lower than those individual effective doses, with no sex difference. Our study suggests that the KOP-r full agonist MSB both alone and in combination with naltrexone shows potential in alcohol "relapse" treatment models
Strain and cocaine-induced differential opioid gene expression may predispose Lewis but not Fischer rats to escalate cocaine self-administration( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Abstract: The aim of the present study was to investigate alterations in gene expression of opioid system components induced by extended access (18h) cocaine self-administration and to determine the impact of genetic background in the vulnerability to escalate cocaine intake. Comparing two inbred rat strains, we previously reported that Lewis rats progressively escalated cocaine consumption compared to Fischer rats, in a new translational model of intravenous cocaine self-administration, which included 14 sessions of 18-h operant sessions in which rats were allowed to select the cocaine unit dose to self-administer. We compare here Fischer and Lewis rats in the gene expression of endogenous opioid peptides (Pomc, Penk, Pdyn) and cognate receptors (Oprm, Oprk and Oprd) in reward-related brain regions, after exposure to either cocaine self-administration or yoked-saline, in the aforementioned translational paradigm. We performed a correlation analysis between the mRNA level, found in the Dorsal Striatum (DS), Nucleus accumbens (NAcc) shell and core respectively, and individual cocaine intake. Our findings show that the gene expression of all the aforementioned opioid genes exhibit strain-dependent differences in the DS, in absence of cocaine exposure. Also, different strain-specific cocaine-induced mRNA expression of Oprm and Oprk was found in DS. Only few differences were found in the ventral parts of the striatum. Moreover, gene expression level of Pdyn, Penk, Oprk, and Oprm in the DS was significantly correlated with cocaine intake only in Fischer rats. Overall, these data shed light on potential genetic differences which may predispose of subjects to initiate and escalate cocaine consumption. Highlights: Lewis, but not Fischer rats, escalate cocaine intake during 14 extended access (18 h) self-administration sessions. Cocaine-induced gene expression changes were observed primarily in the dorsal, but not the ventral, part of the striatum. Strain differences were observed in basal striatal level of Pomc, Pdyn, Penk, Oprm, Oprk, and Oprd mRNA. mRNA level of Pdyn and Oprk, in the Dorsal Striatum correlates with individual cocaine intake selectively in Fischer rats
A study of the pigments in yellow carnations by Mary Jeanne Kreek( )

1 edition published in 1958 in English and held by 1 WorldCat member library worldwide

Driven to Extinction by Mary Jeanne Kreek( )

1 edition published in 2011 in English and held by 1 WorldCat member library worldwide

Could more than a million species disappear in the 21st century? Written by a leading scientist in the field, Driven to Extinction draws upon fascinating case studies from around the world, providing balanced and well-reasoned insight into the potential impacts of climate change on the diversity of life. Richard Pearson focuses on the science of the issue, revealing what has happened?as well as what is likely to happen?to some of the world's weirdest and most wonderful species as global temperatures continue to rise
Il trattamento con metadone a mantenimento : passato, presente e futuro by Mary Jeanne Kreek( )

1 edition published in 1997 in Italian and held by 1 WorldCat member library worldwide

Adolescent oxycodone self administration alters subsequent oxycodone-induced conditioned place preference and anti-nociceptive effect in C57BL/6J mice in adulthood( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Abstract: Adolescent and young adult abuse of short-acting MOP-r agonists such as oxycodone is a pressing public health issue. Few preclinical studies have examined how adolescent exposure to oxycodone impacts its effects in the transition to adulthood. Objective: To determine in mice how chronic adolescent oxycodone self-administration (SA) affects subsequent oxycodone-induced conditioned place preference (CPP), locomotor activity, and anti-nociception once mice reach early adulthood. Methods: Adolescent C57BL/6J male mice (4 weeks old, n=6-11) and adult mice (10 weeks old, n=6-10) were surgically implanted with indwelling jugular catheters. Mice then acquired oxycodone self-administration (14 consecutive 2-hr daily sessions; 0.25mg/kg/infusion) followed by a 14-day drug-free (withdrawal) period in home cage. After the 14-day drug-free period, mice underwent a 10-day oxycodone CPP procedure (0, 1, 3, 10mg/kg i.p.) or were tested for acute oxycodone-induced antinociception in the hot plate assay (3.35, 5, 7.5mg/kg i.p.). Results: Mice that self-administered oxycodone during adolescence exhibited greater oxycodone-induced CPP (at the 3mg/kg dose) than their yoked saline controls and mice that self-administered oxycodone during adulthood. Oxycodone dose-dependently increased locomotor activity, but sensitization developed only to the 3mg/kg in the mice that underwent oxycodone self-administration as adolescents. Mice that self-administered oxycodone as adolescents decreased in the anti-nociceptive effects of oxycodone in one dose (5mg/kg), whereas animals that self-administered oxycodone as adults did not show this effect. Conclusion: Chronic adolescent oxycodone self-administration led to increased oxycodone-induced CPP (primarily 1 and 3mg/kg, i.p.) and reduced antinociceptive effect of oxycodone (5mg/kg, i.p.) in adulthood. Highlights: Adolescent oxycodone SA enhanced 1 and 3 mg/kg oxycodone-induced CPP in early adulthood. Adolescent oxycodone SA resulted in a sensitization of locomotor activity induced by 3 mg/kg oxycodone in early adulthood. Adolescent oxycodone SA led to tolerance in oxycodone (5 mg/kg)-induced nociception in early adulthood
Comprendere la tossicodipendenza : intuizioni dalla genetica, dal comportamento e dalla terapia( )

1 edition published in 2010 in Italian and held by 1 WorldCat member library worldwide

Methadone and beyond : medication and its role in treating addiction by Mary Jeanne Kreek( Visual )

1 edition published in 2002 in English and held by 1 WorldCat member library worldwide

Oprm1 A112G, a single nucleotide polymorphism, alters expression of stress-responsive genes in multiple brain regions in male and female mice by Devon Collins( )

1 edition published in 2018 in English and held by 0 WorldCat member libraries worldwide

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Audience level: 0.48 (from 0.24 for Welcome to ... to 1.00 for Scientists ...)

WorldCat IdentitiesRelated Identities
Alternative Names
Kreek, Mary J.

Mary Jeanne Kreek American neurobiologist

Mary Jeanne Kreek wetenschapper