WorldCat Identities

Mathé, Georges

Overview
Works: 241 works in 781 publications in 5 languages and 6,029 library holdings
Genres: Conference papers and proceedings  Classification 
Roles: Author, Editor, Publishing director, Thesis advisor, Contributor, Other, Author of introduction, Creator, Interviewee, 956, Opponent, Narrator, Author of afterword, colophon, etc., Restager , Honoree
Classifications: RC261, 616.994061
Publication Timeline
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Most widely held works by Georges Mathé
Scientific basis of cancer chemotherapy by Georges Mathé( Book )

24 editions published between 1969 and 2014 in English and German and held by 261 WorldCat member libraries worldwide

Scientific Basis of Cancer Chemotherapy focuses on methods and approaches in the treatment of cancer, including detection, chemotherapeutic agents, and hormonal therapy. The selection first offers information on the detection of anti-cancer agents through screening tests and extracellular factors affecting the response of tumors to chemotherapeutic agents. Discussions focus on induced and transplanted tumors, alkylating agents, anti-folics, rate of excretion, dosage regimen, and extra-cellular deactivation. The text then elaborates on intracellular factors influencing the response of tumo
Cancer active immunotherapy, immunoprophylaxis, and immunorestoration : an introduction by Georges Mathé( Book )

17 editions published between 1976 and 2012 in English and German and held by 248 WorldCat member libraries worldwide

I would like to thank all my co-workers who have collaborated with me, from 1963 until now, in biological and clinical research in the field of cancer active immunotherapy, of its immuno­ prevention and immunorestoration. They will often be quoted in this book. I am particularly grateful to those who have helped me to write it by reviewing some chapters: D. BELPOMME, J. F. DOR~, IRENE FLORENTIN, A. GOUTNER, I. J. Hm, R. HUCHET and MARIE-CHRISTINE SIMMLER. I also thank NICOLE VRIZ, MARIE-CLAUDE SCHNEIDER, FENELLARIsELEY and M. JUVET for their willing and efficient co-operation in the preperation of the manuscript. I am finally grateful to all authors of books or articles who authorized me to reproduce their figures or tables. Paris, April 1976 G. MAT~ Contents Chapter 1. Introduction and Definitions 1 Chapter 2. Biological Basis: Tumour Associated Antigens, the Immune Machinery and Its Behaviour Concerning Cancer Cells 5 2. 1. Tumour-Associated Antigens 5 2. 2. The Immune Machinery 19 2. 2. 1. Humoral Mediated Immunity and Cell Mediated Immunity 19 2. 2. 2. T- and B-Lymphocyte and Monocyte Differen­ tiation 22 2. 2. 3. T-Lymphocyte Functions 25 2. 2. 4. B-Lymphocyte Functions 30 2. 2. 5. Macrophage Functions 31 2. 2. 6. K-Cell Function 32 2. 3. The Immune Machinery and Cancer Cells 33 2. 3. 1. Mechanisms Involved in Tumour Cell Rejec­ tion 33 2. 3. 1. 1. In vivo Evidence for Tumour Immunity 33 2. 3. 1. 2
Lymphoid neoplasias by Georges Mathé( Book )

24 editions published in 1978 in 3 languages and held by 239 WorldCat member libraries worldwide

Adjuvant therapies of cancer( Book )

12 editions published between 1981 and 1982 in English and German and held by 216 WorldCat member libraries worldwide

Histological and cytological typing of neoplastic diseases of haematopoietic and lymphoid tissues by Georges Mathé( Book )

14 editions published in 1976 in English and Italian and held by 208 WorldCat member libraries worldwide

Lymphocytes, macrophages, and cancer by Organisation européenne de recherche sur le traitement du cancer( Book )

13 editions published between 1975 and 1976 in English and German and held by 207 WorldCat member libraries worldwide

Fresh living Bacillus Calmette-Guerin (BeG), injected i.v. into (C57BI/ 6xDBA/2)FI mice, activated peritoneal macrophages rendering them highly cytotoxic for tumor cells in vitro. This cytotoxic activity w̃s already maximal 14 days after injection of 1 mg of BCG and remained stable when 3 or 5 mg of BCG were given. At the same time spleen cells of the BCG-treat̃d mice showed strongly depressed responses to the T-cell mitogens,PHA and Con A, irrespective of the dose of BCG injected. The inhibitory effect was shown to be mediated by suppressor cells which had characteristics of macrophages since they could be removed by carbonyl iron and magnet treatment and were adherent to plastic. In contrast to it was observed after injec­ tion of 1 mg of BCG, these suppressor cells alone did not account for the depression of T-cell re.sponses induced by higher doses of BCG. Nylon-nonadherent cell populations obtained from spleen cells treated with 3 or 5 mg BCG partially retained the inhibitory activity suggesting that suppressor T cells were also induced after injection of high doses of BCG. In contrast, the responses to the B-cell mitogen LPS of unfractionated and macrophage-depleted spleen cells were not affected or significantly enhanced depending on the dose of BCG injected
Aseptic environments and cancer treatment( Book )

12 editions published in 1970 in English and German and held by 204 WorldCat member libraries worldwide

The 1969 Proceedings of the Plenary Session of the European Organization for Research on Treatment of Cancer have been divided between two volumes of a com pletely different nature. Volume 29, Aseptic Environments and Cancer Treatment, deals not only with the treatment of all types of cancer but also with aplastic treatment of bone marrow and certain other pathological conditions, such as immunological insufficiency, bums etc. Hence the volume will be of interest not only to carcinologists and haematologists but also to paediatricians, surgical units, intensive-care units, hospital administrators and architects and engineers who specialize in hospital design and equipment. Volume 30, Advances in the Treatment of Acute (Blastic) Leukemias, deals with a particular form of cancer and will have a more restricted readership of carcinologists specializing in leukemia and all haematologists. Paris, April 1970 GEORGES MATHE Contents Introduction. G. MATHE. 1 Five Years Experience of the Clinical Use of a Pathogen-Free Isolation Unit. G. MATHE, M. SCHNEIDER, 1. SCHWARZENBERG, J. 1. AMIEL, A. CATTAN, J.R. SCHLUMBERGER, M. HAYAT, F. DE VASSAL, CL. JASMIN, and CL. ROSEN- FELD. With 3 Figures . 3 Protected Environments and the Use of Antibiotics. H.E.M. KAY, J. BYRNE, B. JAMESON, and J. LYNCH . 14 Protected Environment, Prophylactic Antibiotics and Cancer Chemotherapy
Complications of cancer chemotherapy by Georges Mathé( Book )

13 editions published in 1974 in English and German and held by 203 WorldCat member libraries worldwide

G. MATHE and R. K. OLDHAM'̃ Institut de Cancerologie et d'Immunogem!tique, Hopital Paul Brousse, Villejuif Since the last war, cancer chemotherapy has been the object of very intensive and expensive research. Nevertheless, its development has been very slow, and its ultimate potential is today somewhat in doubt. In doubt because it does not cure any cancer patients except a) females carrying placental choriocarcinoma, a semi-allogenic tumor, in which case, cure may be in­ fluenced by immune rejection, and b) children suffering from Burkitt's tumor, where the probable reason for the cure is that all the neoplastic cells are in the cycle, which is a unique condition among all the human tumor varieties. Whether the long term survivors in acute leukemia, lymphomas, certain sarcomas and certain testicular tumors are "cures" will require longer follow-up. The idea that chemotherapy does not cure most cancer patients because all their neoplastic cells are not in cycle has led to the use of drug combinations. Whatever they are, "cocktail combinations" which are made up of drugs given according to any timing, or scientific combinations, based on pharmacodynamics, pharmaco­ kinetics or cell kinetics data, are more toxic than single drugs, and are all the more toxic as the number of drugs in the combination is increased
Tactics and strategy in cancer treatment by Organisation européenne de recherche sur le traitement du cancer( Book )

13 editions published between 1976 and 1977 in English and German and held by 203 WorldCat member libraries worldwide

Tactics is the art of combining the action of troops or the proper means of different arms with the object of obtaining the maximum success at combat. Strategy is the art of combining the action of aB the military forces with a view to victory. This work, wh ich publishes the communications at the Annual General Meeting of the EORTC, wh ich was held in Paris in lune 1976, was devoted to tactics and to the therapeutic strategy with a view to the recovery of cancer patients. Table of Contents v Preface . I. Tactics G. MATHE: Tactics in Cancer Treatment: Introduction 1 1. Surgery F. ECONOMIDES and M. BRULEy-RosSET: Effects of the Removal of the Regional Lymph Nodes on the Survival of Mice Bearing B16 Melanoma or EAkR Lymphosarcoma . 2 U. VERONESI: Regional Lymph Node Dissection in Melanoma of the Limbs. Stage I-A Cooperative International Trial . 8 2. Chemotherapy G. MATHE, O. HALLE-PANNENKO, and C. BOURUT: Effectiveness of Murine Leukemia Chemotherapy According to the Immune State: Reconsideration of Correlations Between Chemotherapy, Tumour Cell Killing, and Survival Time 9 A. J. S. DAVIES: C!"temotherapy of Tumours in Immuno-deprived Mice 13 P. POUILLART, G. MATHE, T. PALANGJE, J. LHERITIER, M. PmSSON, P. HUGUENIN, H. GAUTIER, P. MORIN, and R. PARROT: Treatment of Malignant Gliomas and Brain Metastases in Adults Using a Combination of Adriamycin, VM 26 and CCNU- Results of Type 11 Trial . 17 3. lmmunotherapy L. OLSSON: Immunologie and Cytokinetic Parameters of BCG-induced Growth Control of a Murine Leukemia
Cancer chemotherapy : its role in the treatment strategy of hematologic malignancies and solid tumors by Albert Clarysse( Book )

16 editions published between 1976 and 2014 in English and German and held by 200 WorldCat member libraries worldwide

Cancer chemo- and immunopharmacology by European Organization for Research on Treatment of Cancer( Book )

19 editions published in 1980 in English and held by 197 WorldCat member libraries worldwide

Nomenclature, methodology and results of clinical trials in acute leukemias( Book )

20 editions published between 1973 and 1974 in English and German and held by 188 WorldCat member libraries worldwide

Scientific and Ethical Discipline in Clinical Trials on Acute Leukemia G. MATHE Institut de Cancerologie ct d'Immunogenetique "', Hi'ipital Paul-Brousse "."", Villejuif/France Clinical research is still in an evolutionary stage. Although scientific technology was readily accepted and applied, scientific methodology has been accepted much more slowly and is very rarely properly applied. There are three reasons why this is so. First, medical ethics frequently limits the applicability of clinical research, for doctors have to be more than scientists. They must also remain moral philosophers, as they were before medicine became a science. Second, the heterogeneity of the material on which clinical researchers work in studying human diseases makes the application of scientific methodology difficult. Third, researchers must publish. This means that they must obtain publishable results, and too often this means results in accordance with established concepts, easily accepted by the editors of established journals, which are read by the establishment. It is the privilege of too many people to be able to accept "truth" and recipes from other people and confirm their truth and results. It is the mission of a very few others to accept nothing as "truth" and to consider no recipe ideal, either in concept or detail
Investigation and stimulation of immunity in cancer patients by Georges Mathe( Book )

12 editions published in 1974 in 3 languages and held by 173 WorldCat member libraries worldwide

Advances in the treatment of acute (blastic) leukemias by European Organization for Research on Treatment of Cancer( Book )

17 editions published in 1970 in English and German and held by 164 WorldCat member libraries worldwide

Advance in transplantation; proceedings of the first international congress of the Transplantation Society, Paris, 27-30 June 1967 by Transplantation Society( Book )

13 editions published between 1968 and 1969 in English and Undetermined and held by 153 WorldCat member libraries worldwide

Pathophysiological aspects of cancer epidemiology by Georges MATHE( Book )

8 editions published in 1985 in English and held by 153 WorldCat member libraries worldwide

Adjuvant therapies and markers of post-surgical minimal residual disease by European Organization for Research on Treatment of Cancer( Book )

6 editions published in 1979 in English and held by 148 WorldCat member libraries worldwide

Bone marrow transplantation and leucocyte transfusions by Georges Mathé( Book )

6 editions published in 1971 in English and held by 122 WorldCat member libraries worldwide

Sémiologie médicale by Georges Mathé( Book )

14 editions published between 1965 and 1981 in French and Undetermined and held by 103 WorldCat member libraries worldwide

Lymphoid neoplasias II: clinical and therapeutic aspects. Papers presented at a CNRS International Colloquium, June 22-24, 1977( Book )

4 editions published in 1978 in English and held by 16 WorldCat member libraries worldwide

 
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Alternative Names
Georges Mathé Frans immunoloog (1922-2010)

Georges Mathé französischer Mediziner

Georges Mathé French immunologist

Mate, Ž. 1922-2010

Mathé, G.

Mathé, G. 1922-2010

Mathé, G. (Georges)

Mathé, G. (Georges), 1922-2010

Mathé, Georges

Матэ Ж.

Матэ, Ж. (Жорж)

乔治·马特

Languages
English (240)

German (18)

French (12)

Italian (1)

Spanish (1)