WorldCat Identities

Kiianmaa, K. (Kalervo)

Overview
Works: 19 works in 55 publications in 3 languages and 360 library holdings
Genres: Conference papers and proceedings 
Roles: Author, Editor, Other
Publication Timeline
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Most widely held works by K Kiianmaa
Animal models in alcohol research by International Conference on Animal Models in Alcohol Research( Book )

8 editions published in 1980 in English and held by 166 WorldCat member libraries worldwide

Advances in biomedical alcohol research : Third Congress of the International Society for Biomedical Research on Alcoholism, Helsinki, Finland, 8-13 June, 1986 by International Society for Biomedical Research on Alcoholism( Book )

8 editions published in 1987 in English and held by 82 WorldCat member libraries worldwide

The Effects of centrally active drugs on voluntary alcohol consumption : satellite symposium to the Sixth International Congress of Pharmacology, July 26, 1986, Helsinki, Finland by Symposium on the Effects of Centrally Active Drugs on Voluntary Alcohol Consumption( Book )

9 editions published in 1975 in English and held by 51 WorldCat member libraries worldwide

Genetic aspects of alcoholism : proceedings of the satellite symposium "Alcohol and Genetics" held in Sapporo, Japan, June 23-24, 1988, fourth congress of the International Society for Biomedical Research on Alcoholism by International Society for Biomedical Research on Alcoholism( Book )

5 editions published in 1989 in English and held by 27 WorldCat member libraries worldwide

Role of brain monoamines in ethanol consumption and acute intoxination of rats by Kalervo Kiianmaa( Book )

6 editions published in 1980 in English and Finnish and held by 11 WorldCat member libraries worldwide

Animal models in alcohol research : proceedings of an international conference; Helsinki, 4th-8th June, 1979( Book )

1 edition published in 1980 in English and held by 3 WorldCat member libraries worldwide

Abstracts by Nordic Meeting on Biological Alcohol Research( Book )

2 editions published in 1980 in English and held by 3 WorldCat member libraries worldwide

Alkoholi : vaikutukset elimistöön ja terveyteen( Book )

2 editions published in 1987 in Finnish and held by 3 WorldCat member libraries worldwide

Genetic aspects of alcoholism( Book )

2 editions published in 1988 in English and held by 2 WorldCat member libraries worldwide

Prevalence and influence of cys407* Grm2 mutation in Hannover-derived Wistar rats mGlu2 receptor loss links to alcohol intake, risk taking and emotional behaviour by Christian M Wood( )

2 editions published in 2017 in English and held by 2 WorldCat member libraries worldwide

Abstract: Modulation of metabotropic glutamate 2 (mGlu2) receptor function has huge potential for treating psychiatric and neurological diseases. Development of drugs acting on mGlu2 receptors depends on the development and use of translatable animal models of disease. We report here a stop codon mutation at cysteine 407 in Grm2 (cys407*) that is common in some Wistar rats. Therefore, researchers in this field need to be aware of strains with this mutation. Our genotypic survey found widespread prevalence of the mutation in commercial Wistar strains, particularly those known as Han Wistar. Such Han Wistar rats are ideal for research into the separate roles of mGlu2 and mGlu3 receptors in CNS function. Previous investigations, unknowingly using such mGlu2 receptor-lacking rats, provide insights into the role of mGlu2 receptors in behaviour. The Grm2 mutant rats, which dominate some selectively bred lines, display characteristics of altered emotionality, impulsivity and risk-related behaviours and increased voluntary alcohol intake compared with their mGlu2 receptor-competent counterparts. In addition, the data further emphasize the potential therapeutic role of mGlu2 receptors in psychiatric and neurological disease, and indicate novel methods of studying the role of mGlu2 and mGlu3 receptors. This article is part of the Special Issue entitled 'Metabotropic Glutamate Receptors, 5 years on'. Highlights: Discovery of cys407* mutation in Grm2 of Wistar rats. High prevalence in Han Wistar sub-strains. Grm2 mutation linked with alcohol-preferring rats. Grm2 mutation linked with changes in risk taking and emotional behaviour
Päihdelääketiede( Book )

2 editions published between 1998 and 2003 in Finnish and held by 2 WorldCat member libraries worldwide

Alkoholi : biolääketieteellinen käsikirja( Book )

1 edition published in 1993 in Finnish and held by 1 WorldCat member library worldwide

Etiketti-lehdistä koottuja FI [i.e. FT] Kalervo Kiianmaan artikkeleita by Kalervo Kiianmaa( Book )

1 edition published in 1991 in Finnish and held by 1 WorldCat member library worldwide

First Finnish Symposium on the Biological and Medical Effects of Alcohol, November 6, 1978, Vuoranta, Helsinki, Finland : abstracts by Finnish Symposium on the Biological and Medical Effects of Alcohol( Book )

1 edition published in 1978 in English and held by 1 WorldCat member library worldwide

XI Annual Nordic Meeting on Biological Alcohol Research, April 17-19, 1980, Vuoranta, Helsinki, Finland : abstracts by Nordic Meeting on Biological Alcohol Research( Book )

1 edition published in 1980 in English and held by 1 WorldCat member library worldwide

Alkoholi vaikutukset elimistöön ja terveyteen ; kalvosarja( Book )

1 edition published in 1989 in Finnish and held by 1 WorldCat member library worldwide

Genetic aspects of alcoholism : Satellite symposium on alcohol and genetics : 4th Congress : Papers( Book )

1 edition published in 1989 in English and held by 1 WorldCat member library worldwide

The effects of centrally active drugs on voluntary alcohol consumption( Book )

1 edition published in 1975 in Swedish and held by 1 WorldCat member library worldwide

 
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Audience level: 0.66 (from 0.56 for Animal mod ... to 0.99 for Päihdelä ...)

Alternative Names
Kiianmaa, Kalervo

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