WorldCat Identities

Shepherd, John A.

Overview
Works: 19 works in 81 publications in 3 languages and 908 library holdings
Genres: History  Biography 
Roles: Author
Classifications: RD540, 617.55
Publication Timeline
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Most widely held works by John A Shepherd
Surgery of the acute abdomen by John A Shepherd( Book )

16 editions published between 1960 and 1968 in English and held by 166 WorldCat member libraries worldwide

Spencer Wells: the life and work of a Victorian surgeon by John A Shepherd( Book )

13 editions published in 1965 in English and Undetermined and held by 144 WorldCat member libraries worldwide

Simpson and Syme of Edinburgh by John A Shepherd( Book )

5 editions published in 1969 in English and Greek, Modern and held by 139 WorldCat member libraries worldwide

The Crimean doctors : a history of the British medical services in the Crimean War by John A Shepherd( Book )

18 editions published in 1991 in English and held by 114 WorldCat member libraries worldwide

Management of the acute abdomen by John A Shepherd( Book )

5 editions published in 1982 in English and Undetermined and held by 102 WorldCat member libraries worldwide

Lawson Tait, the rebellious surgeon (1845-1899) by John A Shepherd( Book )

4 editions published in 1980 in English and held by 95 WorldCat member libraries worldwide

Wells, Thomas Spencer / Porträt
A concise surgery of the acute abdomen by John A Shepherd( Book )

5 editions published in 1975 in English and held by 72 WorldCat member libraries worldwide

A history of the Liverpool Medical Institution by John A Shepherd( Book )

2 editions published in 1979 in English and held by 49 WorldCat member libraries worldwide

Medizinische Gesellschaften / England / Geschichte
An investigation of the relationships between the learning strategies and the assessment performances of students of actuarial studies by John A Shepherd( Book )

1 edition published in 1992 in English and held by 13 WorldCat member libraries worldwide

Urgencias quirúrgicas abdominales by John A Shepherd( )

2 editions published in 1979 in Spanish and held by 4 WorldCat member libraries worldwide

Is Breast Densitometry a Measure of Breast Cancer Risk( Book )

2 editions published between 2001 and 2002 in English and held by 2 WorldCat member libraries worldwide

Perhaps the least recognized risk factor for breast cancer is breast density. Other than age, breast density, as measured using the radiographic contrast in mammograms between fat and nonfatty tissue, has been shown to be one of the strongest indicators of breast cancer risk available. The primary aim of our research is to fully develop new technologies, dual and single energy x-ray absorptiometry (DXA and SXA), for breast densitometry that could be used to clinically assess the risk of breast cancer and to serve as a sensitive and highly reproducible surrogate marker for testing new methods for preventing breast cancer. DXA %FAT was found to be highly correlated to phantom percent glandular density (r> 0.998). In addition, DXA %FAT was found to be highly correlated to mammographic density using excised cadaveric breasts (adjusted = 0.83). DXA precision (SD) on whole breast tissue samples was 0.5% without repositioning and 1.1% with breast repositioning. Based on this validation of the DXA technique, we have constructed an In vivo DXA positioning aid to be used on commercial DXA equipment and in planned clinical validation trials. With regards to SXA, a workstation and a dynamically adjustable phantom have been designed and constructed. However, full validation of precision and accuracy have not been completed. We plan to follow these encouraging initial results with a case-control study to show that compositional breast density is as highly or more highly predictive of cancer risk than mammographic density alone
Spencer Wells by John A Shepherd( Book )

1 edition published in 1965 in Undetermined and held by 2 WorldCat member libraries worldwide

Genetically Determined Later Puberty Impacts Lowered Bone Mineral Density in Childhood and Adulthood( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

ABSTRACT: Later puberty associates with lower areal bone mineral density (aBMD), and both are risk factors for osteoporosis. However, the association between puberty timing-associated genetic variants and aBMD during development, and the causal relationship between puberty timing and aBMD, remain uncharacterized. We constructed sex-specific polygenic risk scores (GRS) consisting of 333 genetic variants associated with later puberty in European-descent children in the Bone Mineral Density in Childhood Study (BMDCS), consisting of a longitudinal cohort with up to seven assessments (n = 933) and a cross-sectional cohort (n = 486). These GRS were tested for associations with age- and sex-specific aBMD Z -scores at the lumbar spine (LS), femoral neck (FN), total hip, and distal radius, accounting for clinical covariates using sex-stratified linear mixed models. The causal relationship between puberty timing and aBMD was tested in the BMDCS and in publicly available adult data (GEFOS consortium) using two-sample Mendelian randomization (MR). The puberty-delaying GRS was associated with later puberty and lower LS-aBMD in the BMDCS in both sexes (combined beta ± SE = -0.078 ± 0.024; p = 0.0010). In the MR framework, the puberty-delaying genetic instrument also supported a causal association with lower LS-aBMD and FN-aBMD in adults of both sexes. Our results suggest that pubertal timing is causal for diminished aBMD in a skeletal site- and sex-specific manner that tracks throughout life, potentially impacting later risk for osteoporosis, which should be tested in future studies. © 2017 American Society for Bone and Mineral Research
A study of gold therapy, with special reference to the toxic effects by John A Shepherd( Book )

1 edition published in 1939 in English and held by 1 WorldCat member library worldwide

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia design, results and future prospects by Christel M Middeldorp( )

1 edition published in 2019 in English and held by 1 WorldCat member library worldwide

The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites
The high road to England : the inaugural address delivered at the opening of the 140th session of the Liverpool Medical Institution on 14th October, 1976 by John A Shepherd( Book )

1 edition published in 1976 in English and held by 1 WorldCat member library worldwide

Surgery of the acute abdomen ... Second edition, etc. [With plates.] by John A Shepherd( Book )

1 edition published in 1968 in English and held by 1 WorldCat member library worldwide

The life and work of a Victorian surgeon by John A Shepherd( Book )

1 edition published in 1965 in English and held by 1 WorldCat member library worldwide

 
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Audience Level
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Audience level: 0.72 (from 0.66 for Lawson Tai ... to 1.00 for The evolut ...)

Alternative Names
Shepherd, John A.

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