WorldCat Identities

Sesterhenn, I.

Overview
Works: 21 works in 82 publications in 3 languages and 1,086 library holdings
Genres: Classification  Scientific atlases 
Roles: Editor, Other, Author
Publication Timeline
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Most widely held works by I Sesterhenn
Histological typing of prostate tumours by F. K Mostofi( Book )

17 editions published between 1979 and 2002 in English and held by 337 WorldCat member libraries worldwide

This revision of the book originally published in 1980 is the result of a collaboration among scientists from 10 countries. The authors include not only pathologists but also a urologist and a basic scientist. The second edition - containing 146 colour photographs - is considerably more extensive than its predecessor. A number of new entities, unrecognized in 1980, are included: prostatic intraepithelial neoplasia, which is commonly associated with carcinoma and may also be seen in a biopsy for elevated PSA; basal cell carcinoma; small cell carcinoma; paracrine-endocrine elements; variants of carcinoma; and stromal sarcoma. The criteria for the diagnosis of carcinoma have been expanded, including the minimal criteria. The Gleason grading system, based on growth pattern, is presented in detail. The WHO grading system, based on nuclear anaplasia and glandular differentiation, is more clearly defined
Urologic pathology by Robert O Petersen( Book )

14 editions published between 2006 and 2015 in English and held by 202 WorldCat member libraries worldwide

Featuring over 600 full-color illustrations, the Third Edition of this definitive reference provides comprehensive, current, and authoritative coverage of the entire spectrum of urologic surgical pathology. The book emphasizes diagnostic morphology and includes clinical-pathologic correlations. This thoroughly updated edition clarifies histologic variants of prognostic value in urinary bladder cancers and prostate carcinomas and identifies tumor markers useful in both diagnosis and post-therapy management of cancer patients. Also included are current diagnostic criteria for urothelial carcinom
Histological typing of kidney tumours by Fathollah Keshvar Mostofi( Book )

8 editions published in 1981 in English and held by 177 WorldCat member libraries worldwide

"The second edition of this book, originally published in 1981, is the result of a collaborative effort of pathologists from 6 countries. It is more extensive than the first edition. Renal adenomas have been presented in more detail. Several new entities unrecognized in 1981 have been discussed including metanephric adenoma, chromophobe carcinoma, and renal medullary carcinoma. More extensive definition and discussion of nephroblastic lesions is given including mesoblastic nephroma and cystic nephroma. Two new entities are included: clear cell sarcoma and rhabdoid tumour. A list of miscellaneous tumours such as small cell carcinoma, ossifying renal tumour, renal hamartoma, and nephrogenic adenofibroma is also added. A number of new tumour-like lesions have been included. The text of the revised edition contains 145 colour photomicrographs."--BOOK JACKET
Histological typing of testis tumours by Fathollah Keshvar Mostofi( Book )

9 editions published between 1997 and 1998 in English and held by 151 WorldCat member libraries worldwide

"The second edition of this book is the result of collaborative efforts of pathologists from 9 countries. It is more extensive than the previous edition published in 1977. The basic histological classification of the various categories has been retained since it has gained world-wide popularity; however, the individual categories have been described in more detail. A number of new entities have been included: placental site trophoblastic tumour, large cell calcifying Sertoli cell tumour, cystic granulosa cell tumour of infancy, tumour of ovarian epithelial type, testicular lesion of adrenogenital syndrome, and testicular lesion of androgen insensitivity syndrome. Since the first edition, a number of tumour markers have been used in clinical diagnosis, staging, and monitoring the response to therapy. The cells of origin of the two widely used markers have been identified. This revised edition contains 175 colour photomicrographs."--BOOK JACKET
Histological typing of urinary bladder tumours by Fathollah Keshvor Mostofi( Book )

7 editions published in 1999 in English and held by 139 WorldCat member libraries worldwide

"The 1973 WHO classification of bladder tumours anticipated a probable need for eventual revision of the criteria for diagnosing papillary and flat bladder neoplasia. A workshop sponsored by WHO consisting of pathologists, urologists, cytologists, oncologists and basic scientists interested in bladder tumours addressed this subject and, after a follow-up meeting sponsored by the International Society of Urological Pathology, the classification and terminology used in this text were agreed upon. A major change is in the introduction of a new category: papillary urothelial neoplasm of low malignant potential. Many of the tumours previously designated as papillary transitional cell carcinoma, grade I now fall into that category. Another major change is in the designation of flat lesions, and this includes a definition of carcinoma in situ. Furthermore, a number of variant forms of urothelial carcinomas are included as well as new entities not recognized when the first edition was issued."--BOOK JACKET
Types histologiques des tumeurs de la prostate by F. K Mostofi( Book )

3 editions published in 1980 in French and held by 22 WorldCat member libraries worldwide

Types histologiques des tumeurs du rein by Fathollah K Mostofi( Book )

3 editions published in 1981 in French and held by 20 WorldCat member libraries worldwide

Tipos histológicos de tumores de la próstata by F. K Mostofi( Book )

5 editions published between 1980 and 1982 in Spanish and held by 13 WorldCat member libraries worldwide

Tipos histológicos de tumores del riñon by F. K Mostofi( )

3 editions published in 1981 in Spanish and held by 8 WorldCat member libraries worldwide

Histological typing of kidney tumours( Visual )

1 edition published in 1981 in English and held by 5 WorldCat member libraries worldwide

Interphase Cytogenetics in Breast Tumors P53 Gene Alterations( Book )

2 editions published in 1993 in English and held by 2 WorldCat member libraries worldwide

He purpose of this research is to compare numerical chromosome aberrations and p53 gene alterations in 250 node-negative breast cancers to 250 non-positive breast cancers and their survival. SCOPE: Interphase cytogenetics will be performed in paraffin sections utilizing biotinylated probes specific for centromeric regions of chromosomes 1, 8, 11, 13, 17, 18, and X. Chromosome profiles based on 300 tumor cells will be generated for each patient
Urologic pathology by Robert O Petersen( )

1 edition published in 2009 in English and held by 2 WorldCat member libraries worldwide

Types histologiques des tumeurs du rein by F. K Mostofi( Visual )

1 edition published in 1981 in French and held by 1 WorldCat member library worldwide

World Health Organization classification of tumours : pathology and genetics of tumours of the urinary system and male genital organs by John N Eble( Book )

1 edition published in 2004 in English and held by 1 WorldCat member library worldwide

ERG Expression Levels in Prostate Tumors Reflect Functional Status of the Androgen Receptor (AR) as a Consequence of Fusion of ERG with AR Regulated Gene Promoters( Book )

1 edition published in 2010 in English and held by 1 WorldCat member library worldwide

Expression of the ERG proto-oncogene, is activated in 50-70% of prostate tumors by androgen receptor (AR) mediated signals due to the fusion of AR regulated promoters (primarily TMPRSS2 and to a lesser extent SLC45A3 and NDRG1) to the ERG protein coding sequence. Our previous studies of quantitative expression levels of ERG or TMPRSS2-ERG fusion transcripts have noted that relatively low or no ERG expression in prostate tumors significantly associated with progressive disease. Here, we have tested the hypothesis that ERG expression levels in prostate tumor cells reflect AR transcriptional regulatory function in a given biological context of the tumor progression. Therefore tumors with lower ERG may represent a subset with attenuated AR signaling. Expression of ERG and other AR regulated genes were evaluated in a GeneChip dataset obtained from a panel of laser capture micro-dissected well/moderately differentiated (WD) or poorly differentiated (PD) tumor cells derived from primary tumors of patients, who had no prior androgen ablation treatment. Overall, ERG expression pattern was similar to that of other AR regulated genes. Strikingly low frequency of ERG expression was noted in PD tumor cells (30%) in comparison to WD tumor cells (80%), suggesting for subdued AR function in a significant fraction of tumors with genomic alterations of ERG. By integrating ERG into a panel of defined AR target genes, we developed a cumulative AR Function Index (ARFI), which if validated may have future potential in stratifying patients for targeted therapy on the basis of overall AR functional status in primary tumors
Histological Typing of Kidney Tumours by World Health Organization( Book )

1 edition published in 1981 in English and held by 1 WorldCat member library worldwide

ERG Oncoprotein Expression in Prostate Cancer: Clonal Progression of ERG-Positive Tumor Cells and Potential for ERG-Based Stratification( Book )

1 edition published in 2010 in English and held by 1 WorldCat member library worldwide

Gene fusions prevalent in prostate cancer (CaP) lead to the elevated expression of the ERG protooncogene. ERG activation present in 50-70% of prostate tumors underscores one of the most common oncogenic alterations in CaP. Despite numerous reports of gene fusions and mRNA expression, ERG oncoprotein status in CaP still remains to be defined. Furthermore, development of ERG protein-based assays may provide a new dimension to evaluation of gene fusions involving diverse androgen-regulated promoters and the ERG protein-coding sequence. Through exhaustive evaluations of 132 whole-mount prostates (261 tumor foci and over 200 000 benign glands) for the ERG oncoprotein nuclear expression, we demonstrated 99.9% specificity for detecting prostate tumor cells using a highly specific anti-ERG monoclonal antibody. The ERG oncoprotein expression correlated well with fusion transcript or gene fusion in randomly selected specimens. Strong concordance of ERG-positive foci of prostatic intraepithelial neoplasia (PIN) with ERG-positive carcinoma (82 out of 85 sections with PIN, 96.5%) affirms the biological role of ERG in clonal selection of prostate tumors in 65% (86 out of 132) of patients. Conversely, ERG negative PINs were associated with ERG-negative carcinoma. Taken together, the homogeneous and strong ERG expression detected in individual tumors establishes the potential for ERG oncoprotein-based stratification of CaP
Circulating and intraprostatic sex steroid hormonal profiles in relation to male pattern baldness and chest hair density among men diagnosed with localized prostate cancers( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Abstract : Background: Prospective cohort studies of circulating sex steroid hormones and prostate cancer risk have not provided a consistent association, despite evidence from animal and clinical studies. However, studies using male pattern baldness as a proxy of early-life or cumulative androgen exposure have reported significant associations with aggressive and fatal prostate cancer risk. Given that androgens underlie the development of patterned hair loss and chest hair, we assessed whether these two dermatological characteristics were associated with circulating and intraprostatic concentrations of sex steroid hormones among men diagnosed with localized prostate cancer. Methods: We included 248 prostate cancer patients from the NCI Prostate Tissue Study, who answered surveys and provided a pre-treatment blood sample as well as fresh frozen adjacent normal prostate tissue. Male pattern baldness and chest hair density were assessed by trained nurses before surgery. General linear models estimated geometric means and 95% confidence intervals (95%CIs) of each hormone variable by dermatological phenotype with adjustment for potential confounding variables. Subgroup analyses were performed by Gleason score (<7 vs e") and race (European American vs. African American). Results: We found strong positive associations of balding status with serum testosterone, dihydrotestosterone (DHT), estradiol, and sex hormone-binding globulin (SHBG), and a weak association with elevated intraprostatic testosterone. Conversely, neither circulating nor intraprostatic sex hormones were statistically significantly associated with chest hair density. Age-adjusted correlation between binary balding status and three-level chest hair density was weak (r = 0.05). There was little evidence to suggest that Gleason score or race modified these associations. Conclusions: This study provides evidence that balding status assessed at a mean age of 60 years may serve as a clinical marker for circulating sex hormone concentrations. The weak-to-null associations between balding status and intraprostatic sex hormones reaffirm differences in organ-specific sex hormone metabolism, implying that other sex steroid hormone-related factors (eg, androgen receptor) play important roles in organ-specific androgenic actions, and that other overlapping pathways may be involved in associations between the two complex conditions
Historical Typing of Prostate Tumors by World Health Organization( Book )

1 edition published in 1980 in English and held by 1 WorldCat member library worldwide

 
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Audience level: 0.69 (from 0.45 for Histologic ... to 0.99 for ERG Oncopr ...)

Urologic pathology Urologic pathology
Covers
Urologic pathologyHistological typing of urinary bladder tumoursUrologic pathologyWorld Health Organization classification of tumours : pathology and genetics of tumours of the urinary system and male genital organs
Alternative Names
Sesterhenn, I.

Sesterhenn, I. 1942-

Sesterhenn, I. A.

Sesterhenn, Isabell A.

Sesterhenn, Isabell A. 1942-

Languages