WorldCat Identities

Conn, P. Michael

Overview
Works: 293 works in 1,261 publications in 1 language and 23,676 library holdings
Genres: Handbooks and manuals  Software  Methods (Music)  Conference papers and proceedings  Laboratory manuals 
Roles: Editor, Author, Other, Contributor
Classifications: QP601, 572.6
Publication Timeline
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Most widely held works about P. Michael Conn
 
Most widely held works by P. Michael Conn
Hormone action by Bert W O'Malley( Book )

48 editions published between 1983 and 1989 in English and held by 683 WorldCat member libraries worldwide

FROM THE PREFACE: A survey of the current biological literature will convince even the most skeptical individual of the substantive and pervasive advances that have occurred in neuroendocrinology. It was the observation that this rapid growth resulted in large part from methodological improvements which first suggested the need for this volume. Some of the advances can be easily recognized. High pressure liquid chromatography, once a tool of the solvent chemist, is now a routine analytical and preparative method in biological laboratories. It has enhanced the speed and resolution with which neuroendocrine substances can be separated. Likewise, peptide synthesis, modification, and analysis are no longer the ken of those whose work is dedicated solely to this task, rather, as one of the authors put it, "almost anyone can synthesize a peptide." Analytical advances have extended the sensitivity and specificity of assay techniques. Culture techniques have been devised which allow us to purify and maintain isolated cells and tissue. In turn, these enhancements have revealed the presence and biological roles of new neuroendocrine substances; in other cases, novel and surprising sites of action have been identified for substances already described
The animal research war by P. Michael Conn( Book )

11 editions published in 2008 in English and held by 572 WorldCat member libraries worldwide

Documents the last 20 years of the animal rights assault on biomedical research. This book provides information about animal rights philosophy, tactics, and actions, along with animal research purposes, methods, and triumphs. The authors identify grave dangers posed by the animal rights movement. Unless ordinary citizens understand its nature and unless the volume of violence is turned down, the movement may slowly but effectively shut off the pipeline of medical discovery. They describe the extensive federal regulation of research and the lengths taken to minimize animal pain and suffering
Neuroscience in medicine by P. Michael Conn( Book )

37 editions published between 1994 and 2009 in English and Undetermined and held by 547 WorldCat member libraries worldwide

This textbook reflects the many advances that have occurred in our basic understanding of neurological processes and their clinical significance. Designed specifically for medical students and allied health professionals, the book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relate that science to the understanding of neurological disorders and their treatment. These popular clinical correlations cover, in detail, disorders of the spinal cord, neuronal migration, the autonomic nervous system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia, and abnormalities of cognition, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, and myasthenia gravis. Authoritative and comprehensive, this book provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level
Green fluorescent protein( Book )

12 editions published in 1999 in English and held by 444 WorldCat member libraries worldwide

One of the most important recent discoveries in science is the green fluorescent protein, isolated from a bioluminescent jellyfish. The gene that codes for this protein is active in any type of cell, from microbes to humans, producing a "day-glo" dye visible as a bright green light in the microscope. The power of the gene is that by using recombinant DNA technology. GFP can be spliced to any protein, essentially painting that protein green. When such a spliced protein is inside a cell. Further, time-lapse microscopy can be used to examine how that protein and the cellular components that it is part of move within the cell during the cell's life cycle. This Methods in Enzymology volume deals with the utility of green fluorescent protein (GFP). The OVID database (including MEDLINE, Current Contents, and other sources) lists nine references to GFP for the ten-year period 1985-1994. In contrast, in less than four years thereafter, over 500 references are listed, a testament to the rapid growth of interest in this probe. This volume documents many diverse uses for this interesting molecule in disciplines that broadly span biology. The methods presented include shortcuts and conveniences not included in previously published sources. The techniques are described in a context that allows comparisons to other related methodologies-such comparisons are valuable to readers who must adapt existing procedures to new systems. Also, so far as possible, methodologies have been presented in a manner that stresses their general applicability and potential limitations. The volume provides a substantial and current overview of the extant methodology in the field and a view of its rapid development. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Key Features * Monitoring of Physiological Processes * Localization of Molecules * Special Uses * Mutants * Variants of GFP
Cellular regulators by Anthony R Means( Book )

26 editions published in 1987 in English and Undetermined and held by 438 WorldCat member libraries worldwide

The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences
Confocal microscopy( Book )

11 editions published in 1999 in English and held by 427 WorldCat member libraries worldwide

This volume supplements Volumes 63, 64, 87, and 249 of Methods in Enzymology. These volumes provide a basic source for the quantitative interpretation of enzyme rate data and the analysis of enzyme catalysis. Among the major topics covered are Engergetic Coupling in Enzymatic Reactions, Intermediates and Complexes in Catalysis, Detection and Properties of Low Barrier Hydrogen Bonds, Transition State Determination, and Inhibitors. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemi
Endocrinology : basic and clinical principles by Shlomo Melmed( Book )

29 editions published between 1996 and 2010 in English and held by 418 WorldCat member libraries worldwide

Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, this new edition succinctly summarizes in 450 pages the latest findings on hormone secretion and hormone action, as well as all the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology - from mammalian cells, plants, and insects to animal models and human diseases - with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in man and the lower species, and the mechanisms subserving hormone secretion
Neuropeptide technology : gene expression and neuropeptide receptors by P. Michael Conn( Book )

32 editions published between 1990 and 2013 in English and Undetermined and held by 407 WorldCat member libraries worldwide

Methods in Neurosciences, Volume 6: Neuropeptide Technology: Synthesis, Assay, Purification, and Processing describes procedures and tools of assay useful for the identification, purification, and quantification of neuropeptides and their receptors. This volume is divided into four sections- chemical synthesis and biosynthesis; measurement of neuropeptides; purification and characterization; and neuropeptide degrading and processing enzymes. In these sections, this book specifically discusses the synthesis of peptide substrates for protein kinase C; synthesis of glycosyl neuropeptides; and ult
Laser capture microscopy and microdissection by P. Michael Conn( Book )

15 editions published in 2002 in English and held by 391 WorldCat member libraries worldwide

Basic principles; Specialized uses; Genetic applications
Handbook of proteomic methods by P. Michael Conn( Book )

12 editions published in 2003 in English and Undetermined and held by 311 WorldCat member libraries worldwide

The developing new field of proteomics holds significant promise for a deeper understanding of complicated biological systems, as well as for novel approaches to the cure of disease. In the Handbook of Proteomic Methods, P. Michael Conn has assembled a panel of well-recognized experts to describe a wide range of powerful techniques for identifying and analyzing the diversity of proteins expressed in cells. These readily reproducible proteomic methods range from general to specific techniques, and include methods for data analysis, post-translational modification, and its variants and isoforms. Additional methods demonstrate the application of proteomics to the discovery of serological tumor markers, to identifying the determinants of sensitivity to antitumor drugs, and to specialized fields, such as endocrinology, plant biology, nephrology, and urology. Each fully tested protocol is described in step-by-step detail, complete with tricks of the trade and hints on avoiding pitfalls. The detail of description exceeds that usually found in primary publications. Wide-ranging and practical, the Handbook of Proteomic Methods offers scientists entering, or already active in, the field a fully referenced compendium of easy-to-use proteomic methods-each reflecting the power and promise of proteomics in illuminating complex biological systems and in promoting the development of novel drugs for the amelioration of disease
Ion channels by P. Michael Conn( Book )

16 editions published between 1998 and 1999 in English and held by 286 WorldCat member libraries worldwide

General Description of the Volume: This volume and its companion Volume 293 present techniques for the study of ion channels, ranging from the molecular to the physiological level. These volumes supplement Volume 207 of Methods in Enzymology. General Description of the Series: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Key Features * Among the major topics covered in this volume are: * Physical methods * Purification and reconstitution * Second messengers and biochemical approaches * Special channels
Ion channels by P. Michael Conn( Book )

16 editions published in 1998 in English and held by 282 WorldCat member libraries worldwide

This volume plus its companion, Volume 294, presents cutting edge techniques for the study of ion channels, ranging from the molecular to the physiological level. These volumes supplement Volume 207 of Methods inEnzymology Key Features * Assembly * Genetics * Electrophysiology * Expression Systems * Model Simulations
Handbook of models for human aging by P. Michael Conn( Book )

17 editions published between 2006 and 2011 in English and held by 178 WorldCat member libraries worldwide

This Handbook is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. *Utilizes a multidisciplinary approach *Shows tricks and approaches not available in primary publications *First volume of its kind to combine both methods of study for human aging and animal models *Over 200 illustrations
Imaging in biological research by P. Michael Conn( Book )

16 editions published between 2004 and 2007 in English and Undetermined and held by 155 WorldCat member libraries worldwide

Annotation
G protein coupled receptors : structure( Book )

13 editions published in 2013 in English and held by 116 WorldCat member libraries worldwide

Printbegrænsninger: Der kan printes kapitelvis
Constitutive activity in receptors and other proteins( Book )

22 editions published in 2010 in English and held by 116 WorldCat member libraries worldwide

This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. The chapters written by expert authors who are leaders in the field, provide hints and tricks not available in primary research publications. It is extensively referenced, with useful figures and tables throughout the volume. A. Expert authors who are leaders in the field B. Extensively referenced and useful figures and tables C. Provides hints and tricks to facilitate reproduction of methods
G protein coupled receptors : modeling, activation, interactions and virtual screening by P. Michael Conn( Book )

17 editions published in 2013 in English and held by 115 WorldCat member libraries worldwide

Printbegrænsninger: Der kan printes kapitelvis
Sourcebook of models for biomedical research by P. Michael Conn( Book )

14 editions published in 2008 in English and held by 112 WorldCat member libraries worldwide

The collection of systems represented in the Sourcebook of Models for Biomedical Research reflect the diversity and utility of models that are used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. Some models have the advantage that the reproductive, mitotic, development or aging cycles are rapid compared with those in humans; others are utilized because individual proteins may be studied in an advantageous way and have human homologs. Other organisms are facile to grow in laboratory settings, lend themselves to convenient analyses, have defined genomes or present especially good human models of human or animal disease. The Sourcebook of Models for Biomedical Research is a comprehensive and extensive collection of these important medical parallels. While the entire book is not devoted to the remarkable success of the genomic programs, this work is well represented and indexed within these pages. - Publisher
Molecular biology of protein folding( Book )

16 editions published in 2008 in English and held by 96 WorldCat member libraries worldwide

The importance of protein folding has been recognized for many years. It is the underlying etiology in a large number of human diseases and it appears to be a novel method for cellular regulation of the expression of newly translated proteins. These volumes (Parts A & B) address this important topic. As a volume in Progress in Nucleic Acid Research and Molecular Biology, this book provides the latest information on the expanding research being conducted on protein folding. Illustrates how ubiquitin domain proteins are an ideal model system for experimental and computational studies of protein folding. Discusses structural wrapping and its importance in the contexts of network centrality, molecular disease, drug discovery and molecular theranostic engineering. Chapters written by international authors in engineering, biochemistry, physics, and computer science
Animal models for the study of human disease by P. Michael Conn( Book )

13 editions published between 2013 and 2017 in English and Undetermined and held by 47 WorldCat member libraries worldwide

"Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine. The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, canc."
 
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The animal research war
Alternative Names
Conn, M.

Conn, M. (P. Michael)

Conn, Michael.

Conn, Michael 1949-

Conn, Michael (P. Michael)

Conn, P. M.

Conn, P. M. 1949-

Conn, P. M. (P. Michael)

Conn, P. Michael 1949-

Conn, Patrick M. 1949-

Languages
English (388)

Covers
The animal research warNeuroscience in medicineGreen fluorescent proteinCellular regulatorsConfocal microscopyEndocrinology : basic and clinical principlesLaser capture microscopy and microdissectionHandbook of proteomic methods