WorldCat Identities

Maaløe, Ole

Overview
Works: 43 works in 77 publications in 1 language and 1,677 library holdings
Genres: Conference papers and proceedings  Periodicals 
Roles: Author, Editor, Contributor
Publication Timeline
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Most widely held works about Ole Maaløe
 
Most widely held works by Ole Maaløe
Control of macromolecular synthesis; a study of DNA, RNA, and protein synthesis in bacteria by Ole Maaløe( Book )

10 editions published in 1966 in English and held by 578 WorldCat member libraries worldwide

Control of ribosome synthesis : proceedings of the Alfred Benzon Symposium IX held at the premises of the World Health Organization, Regional Office for Europe, Copenhagen 2-5 June 1975 by Alfred Benzon Symposium( Book )

10 editions published in 1976 in English and held by 253 WorldCat member libraries worldwide

Current topics in microbiology and immunology( )

2 editions published in 1969 in English and held by 80 WorldCat member libraries worldwide

Current topics in microbiology and immunology = Ergebnisse der Mikrobiologie und Immunitätsforschung by W Arber( )

2 editions published in 1975 in English and held by 57 WorldCat member libraries worldwide

The processes involved in herpesvirus replication, latency, and oncogenic transformation, have, in general, been rather poorly defined. A primary reason for this is the size and complexity of the herpesvirus genome. Undoubtedly, a better understanding of the functions of the viral genome in infected and transformed cells will be achieved through studies with temperature-sensitive (ts) mutants of herpesviruses since, theoretically, any essential gene function can be affected by mutants of this type. A. The Herpesviruses A consideration of the genetic analysis of members of the herpesvirus group necessitates a description, albeit brief, of the properties of the group and, most importantly, of their genetic material. The herpesviruses comprise a group of relatively large (100-150 nm), enveloped viruses. The envelope surrounds an icosahedral capsid enclosing a core which contains double­ stranded DNA (ROIZMAN, 1969). The group is thus defined on the basis of a common virion morphology. In addition to a common structure, members of the group share a number of biological properties such as a similar replicative cycle, the ability to cause latent and chronic infections, and the ability to induce antigenic modifications of infected cell membranes. Several herpes­ viruses have been associated recently with malignancies in man and animals (KLEIN, 1972). Herpesviruses are ubiquitous and have been described in over 30 different species (HUNT and MELENDEZ, 1969; WILDY, 1971; FARLEY et aI. , 1972; KAZAMA and SCHORNSTEIN, 1972; NAHMIAS et aI. , 1972; ROlZMAN et aI. , 1973). Their widespread occurrence in nature suggests a common ancestor
Current Topics in Microbiology and Immunology by W Arber( )

1 edition published in 1969 in English and held by 52 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology : Ergebnisse der Mikrobiologie und Immunitätsforschung by W Arber( )

2 editions published in 1968 in English and held by 50 WorldCat member libraries worldwide

Ever since arbovirus infections became known and their relative importance assessed, experiments were designed to elucidate the mode of transmission and the most important natural hosts responsible for perpetuating the infection in nature. Human infections and the disease in wild rodents, birds, and domestic animals were studied in relation to viremia and distribution of the infectious agent in the organism. With increasing epidemiological studies it became apparent that the neural manifestations of the disease are very uncommon, confined only to a small percentage of individuals of the most susceptible species. Various factors have been proposed to explain why in certain instances the virus becomes establish­ ed in the central nervous system and causes a serious or lethal disease. For example, differences in the virulence of the virus strains, varying susceptibility of individuals of one species, or intercurrent circumstances facilitating access of the virus to the central nervous system were alleged. Also, various possible routes of entry of the virus into the brain and spinal cord have been considered
Current topics in microbiology and immunology by W Arber( )

1 edition published in 1970 in English and held by 47 WorldCat member libraries worldwide

Current topics in microbiology and immunology : by W Arber( )

3 editions published in 1974 in English and held by 44 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology by W Arber( )

2 editions published in 1974 in English and held by 44 WorldCat member libraries worldwide

Prominent progress in molecular biology was only made when it became possible to separate functionally distinct molecules by taking advantage of their biophysical properties. Likewise, the analysis of the functions of hetero­ geneous populations of immunocompetent cells, as to the functional properties of their various subpopulations, can not be done until these can be isolated in reasonably pure form by selective fractionation. During the last few years significant advances have been made in this field, and cells have been separated according to size, density or charge (MILLER et aI. , 1969; SHORTMAN, 1968; ANDERSSON, 1973 c), or by taking advantage of more specific surface markers to allow selective depletion or enrichment of a given subpopulation of cells (WIGZELL and ANDERSSON, 1971). Although separation techniques have been used in a variety of cellular systems, they have been particularly useful in the study of reticuloendothelial cells and primarily in the study of cells partici­ pating in the immune responses. Quite extensive reviews have been written which well cover the methods used for separation of cells and the results obtained with the various approaches (WIGZELL and ANDERSSON, 1971; SHORTMAN, 1972). To review this work is becoming a more and more voluminous task. As data rapidly accumulate, we will not try to make such a complete review
Current Topics in Microbiology and Immunology by W Arber( )

2 editions published in 1976 in English and held by 43 WorldCat member libraries worldwide

Current topics in microbiology and immunology by Werner Arber( )

1 edition published in 1973 in English and held by 42 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology by W Arber( )

1 edition published in 1974 in English and held by 42 WorldCat member libraries worldwide

Current topics in microbiology and immunology by W Arber( )

1 edition published in 1972 in English and held by 41 WorldCat member libraries worldwide

Current topics in microbiology and immunology( )

1 edition published in 1978 in English and held by 40 WorldCat member libraries worldwide

... On the relation between alexin & opsonin by Ole Maaløe( Book )

6 editions published in 1946 in English and held by 30 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology.( )

1 edition published in 1978 in English and held by 27 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology : Ergebnisse der Mikrobiologie und Immunitätsforschung by Werner Arber( )

1 edition published in 1972 in English and held by 27 WorldCat member libraries worldwide

Phenomena as diverse as tuberculin sensitivity, delayed sensitivity to soluble proteins other than tuberculin, contact allergy, homograft rejection, experimental autoallergies, and the response to many microorganisms, have been classified as members of the class of immune reactions known as delayed or cellular hypersensitivity. Similarities in time course, histology, and absence of detectable circulating immunoglobulins characterize these cell-mediated immune reactions in vivo. The state of delayed or cellular hypersensitivity can be transferred from one animal to another by means of sensitized living lymphoid cells (CHASE, 1945; LANDSTEINER and CHASE, 1942; MITCHISON, 1954). The responsible cell has been described by GOWANS (1965) as a small lymphocyte. Passive transfer has also been achieved in the human with extracts of sensitized cells (LAWRENCE, 1959). The in vivo characteristic of delayed hypersensitivity from which the class derives its name is the delayed skin reaction. When an antigen is injected intradermally into a previously immunized animal, the typical delayed reaction begins to appear after 4 hours, reaches a peak at 24 hours, and fades after 48 hours. It is grossly characterized by induration, erythyma, and occasionally necrosis. The histology of the delayed reaction has been studied by numerous investigators (COHEN et al., 1967; GELL and HINDE, 1951; KOSUNEN, 1966; KOSUNEN et al., 1963; MCCLUSKEY et al., 1963; WAKSMAN, 1960; WAKSMAN, 1962). Initially dilatation of the capillaries with exudation of fluid and cells occurs
Current Topics in Microbiology and Immunology by W Arber( )

1 edition published in 1977 in English and held by 27 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology by W Arber( )

1 edition published in 1980 in English and held by 26 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology by Werner Henle( )

1 edition published in 1981 in English and held by 25 WorldCat member libraries worldwide

Several discoveries are noteworthy for allowing us to probe the recesses of the virus℗Ư infected cell and to search for cryptic viral genomes which might provide clues in our studies of cancer etiology or developmental biology. One of the most notable was the dis℗Ư covery of reverse transcriptase. This marked a momentous occasion in the history of molecular biology. Not only did it provide insight into the mechanism of persistence of retroviruses but it also provided us with an enzyme that could synthesize a DNA copy of any RNA. This DNA copy could then be used as a hybridization reagent to search for both complementary DNA and viral-specific RNA. Thus one could follow the course of any viral infection or probe in tumor cells for hidden viral genomes. Second, a great deal of credit must be given to the geneticists who isolated the various deletion mutants in the 'avian retrovirus system and thus provided us with the frrst means of isolating gene-spe℗Ư cific probes. Finally, the laboratories which have mapped the genome have provided us with the framework in which to ask very specific questions with our gene-specific probes. Recently, numerous excellent reviews concerning various aspects of the retroviruses have appeared. In this review I shall not even attempt to present a comprehensive review of retroviruses
 
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Audience level: 0.54 (from 0.43 for Control of ... to 1.00 for Recombinan ...)

WorldCat IdentitiesRelated Identities
Alternative Names
Maaløe, O.

Maaløe, O. (Ole)

Languages
English (51)