WorldCat Identities

Holmes, Frederic Lawrence

Overview
Works: 65 works in 240 publications in 2 languages and 10,614 library holdings
Genres: History  Biography  Biography‡vDictionaries  Dictionaries 
Roles: Editor, Publishing director, Author of introduction, Other
Classifications: R920, B
Publication Timeline
Key
Publications about  Frederic Lawrence Holmes Publications about Frederic Lawrence Holmes
Publications by  Frederic Lawrence Holmes Publications by Frederic Lawrence Holmes
posthumous Publications by Frederic Lawrence Holmes, published posthumously.
Most widely held works about Frederic Lawrence Holmes
 
Most widely held works by Frederic Lawrence Holmes
Instruments and experimentation in the history of chemistry ( )
14 editions published between 1999 and 2002 in English and held by 1,838 WorldCat member libraries worldwide
Meselson, Stahl, and the replication of DNA a history of "the most beautiful experiment in biology" by Frederic Lawrence Holmes ( )
12 editions published between 2001 and 2002 in English and held by 1,294 WorldCat member libraries worldwide
In 1957 Matthew Meselson and Frank Stahl produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a 'most beautiful' experiment whose beauty was tied to its simplicity. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research - its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty
Reconceiving the gene Seymour Benzer's adventures in phage genetics by Frederic Lawrence Holmes ( )
10 editions published in 2006 in English and held by 1,267 WorldCat member libraries worldwide
A fascinating and detailed chronicle, "Reconceptualizing the Gene" relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer's accomplishments and discoveries are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age. Drawing on Benzer's remarkably complete record of his experiments, his correspondence, and published sources, Frederic Lawrence Holmes reconstructs how the former physicist initiated his work in phage biology, and how he accomplished his landmark investigation. The book follows Benzer's investigative pathway as his research unfolded and shifted, and as he adapted to opportunities or disappointments as they arose. The story of Benzer's creativity as a researcher is a fascinating story that also reveals intriguing aspects common to the scientific enterprise
Dictionary of scientific biography by Charles Coulston Gillispie ( Book )
16 editions published between 1990 and 2008 in English and held by 807 WorldCat member libraries worldwide
Provides information on the history of science through articles on the professional lives of scientists. All periods of science from classical antiquity to modern times are represented
Lavoisier and the chemistry of life : an exploration of scientific creativity by Frederic Lawrence Holmes ( Book )
13 editions published between 1984 and 1987 in English and Undetermined and held by 708 WorldCat member libraries worldwide
Reworking the bench research notebooks in the history of science by Frederic Lawrence Holmes ( )
16 editions published between 2003 and 2011 in English and held by 691 WorldCat member libraries worldwide
Research records composed of notes and protocols have long played a role in the efforts to understand the origins of what have come to be seen as the established milestones in the development of modern science. The use of research records to probe the nature of scientific investigation itself however is a recent development in the history of science. With Eduard Dijksterhuis, we could address them as a veritable "epistemologiCal laboratory". The purpose of a workshop entitled "Reworking the Bench: Laboratory Notebooks in the History of Science", held at the Max Planck Institute for the History of Science in Berlin was to bring together historians who have been exploiting such resources, to compare the similarities and differences in the materials they had used and and to measure the potential and scope for future explorations of "science in the making" based on such forms of documentation. The contributions which form this volume are based on papers presented at this workshop or written afterward by participants in the discussions. This is the first book that addresses the issue of research notes for writing history of science in a comprehensive manner. Its case studies range from the early modern period to present and cover a broad range of different disciplines
Claude Bernard and animal chemistry; the emergence of a scientist by Frederic Lawrence Holmes ( Book )
13 editions published in 1974 in English and held by 658 WorldCat member libraries worldwide
Hans Krebs by Frederic Lawrence Holmes ( )
9 editions published in 1993 in English and held by 466 WorldCat member libraries worldwide
This comprehensive volume completes Frederic Holmes' notable and detailed biography of Hans Krebs, from the investigator's early development through the major phase of his groundbreaking investigation, which lay the foundations upon which the modern structure of intermediary metabolism is built. With access to Krebs' research notebooks as well as to Krebs himself through more than five years of personal interviews, the author provides an insightful analysis of Hans Krebs and of the scientific process as a whole. The first volume, published in 1991, covered Krebs' formative years in Germany, hi
Antoine Lavoisier, the next crucial year, or The sources of his quantitative method in chemistry by Frederic Lawrence Holmes ( Book )
8 editions published between 1997 and 1998 in English and held by 395 WorldCat member libraries worldwide
Through his development of quantitative experimental methods, the chemist Antoine Lavoisier (1743-1794) implemented a principle that many regard as the cornerstone of modern science: in every operation there is an equal quantity of material before and after the operation. The origin of Lavoisier's methods, however, has remained a missing piece in this remarkable episode of scientific history, perhaps because the talented young scientist himself was not prepared for the journey his discoveries would set before him. In this book, Frederic Lawrence Holmes suggests that Lavoisier gradually came to understand the nature and power of his quantitative method during the year 1773, when he began to carry out a research program on the fixation and release of airs. Drawing upon Lavoisier's surviving laboratory notebooks, Holmes presents an engaging portrait of a scientist whose innovative experiments would make him the leader of one of the great upheavals in the history of science
Hans Krebs by Frederic Lawrence Holmes ( Book )
11 editions published between 1991 and 1993 in English and German and held by 388 WorldCat member libraries worldwide
This comprehensive volume completes Frederic Holmes's notable and detailed biography of Hans Krebs, from the investigator's early development through the major phase of his groundbreaking investigation, which lay the foundations upon which the modern structure of intermediary metabolism is built. With access to Krebs's research notebooks as well as to Krebs himself through more than five years of personal interviews, the author provides an insightful analysis of Hans Krebs and of the scientific process as a whole. The first volume, published in 1991, covered Krebs's formative years in Germany, his work with Otto Warburg, and his discovery of the urea cycle in 1932. This second volume reconstructs the investigative pathway and the professional and personal life of Hans Krebs, from the time of his arrival in England in 1933 until 1937, when he made the discovery for which he is best known-the formulation of the citric acid cycle. Holmes portrays Krebs's activity at the intimate level of daily interactions of thought and action, from which the characteristic patterns of scientific creativity can best be seen.; Holmes's fascinating portrait of Krebs integrates the great scientist's investigative pathways with his personal life. The result is an illuminating analysis of both man and scientist that will be of interest to biochemists and historians of science
Investigative pathways : patterns and stages in the careers of experimental scientists by Frederic Lawrence Holmes ( Book )
6 editions published in 2004 in English and held by 362 WorldCat member libraries worldwide
"This fascinating book is an investigation of scientific creativity. Following the research pathways of outstanding scientists over the past three centuries, it finds common features in their careers and their landmark discoveries and sheds light on the nature of long-term experimental research."--BOOK JACKET
The Investigative enterprise : experimental physiology in nineteenth-century medicine ( Book )
6 editions published in 1988 in English and held by 349 WorldCat member libraries worldwide
Dictionary of scientific biography : Supplement II ( Book )
5 editions published in 1990 in English and held by 267 WorldCat member libraries worldwide
Complete dictionary of scientific biography by Charles Coulston Gillispie ( )
3 editions published between 2007 and 2008 in English and held by 253 WorldCat member libraries worldwide
Provides information on the history of science through articles on the professional lives of scientists. All periods of science from classical antiquity to modern times are represented
Architect of intermediary metabolism by Frederic Lawrence Holmes ( )
5 editions published in 1993 in English and held by 165 WorldCat member libraries worldwide
Hans Krebs by Frederic Lawrence Holmes ( )
8 editions published in 1991 in English and German and held by 144 WorldCat member libraries worldwide
Eighteenth-century chemistry as an investigative enterprise by Frederic Lawrence Holmes ( Book )
5 editions published in 1989 in English and held by 136 WorldCat member libraries worldwide
Research schools : historical reappraisals ( Book )
6 editions published in 1993 in English and held by 109 WorldCat member libraries worldwide
Between biology and medicine : the formation of intermediary metabolism by Frederic Lawrence Holmes ( Book )
6 editions published in 1992 in English and held by 92 WorldCat member libraries worldwide
The sickly Stuarts the medical downfall of a dynasty by Frederic Lawrence Holmes ( Book )
1 edition published in 2005 in English and held by 52 WorldCat member libraries worldwide
 
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Alternative Names
Holmes, F. L.
Holmes, Frederic L. 1932-2003
Holmes, Frederic Lawrence
Languages
English (171)
German (2)
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