WorldCat Identities

Fission Product Inhalation Program

Overview
Works: 20 works in 29 publications in 1 language and 82 library holdings
Genres: Periodicals 
Classifications: QR185,
Publication Timeline
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Most widely held works about Fission Product Inhalation Program
 
Most widely held works by Fission Product Inhalation Program
Transport of relatively insoluble materials from lung to lymph nodes by R. G Thomas( Book )

2 editions published in 1965 in English and held by 5 WorldCat member libraries worldwide

On the calibration of cascade impactors by T. T Mercer( Book )

1 edition published in 1962 in English and held by 4 WorldCat member libraries worldwide

The stage constants of cascade impactors by Thomas T Mercer( Book )

2 editions published in 1963 in English and held by 3 WorldCat member libraries worldwide

The particle size distributions which would be found on each stage of a cascade impactor when used to sample an aerosol having a lognormal mass distribution have been calculated. Three impactors, differing with respect to the collection characteristics of the various stages, were assumed. Samples were obtained from hypothetical aerosols having a wide range of distribution parameters. It is shown that for a particular aerosol the particle sizes appear to be log normally distributed on all stages and that the mass median diameter for a given stage, calculated from the number distribution on that stage, is a good estimate of the true mass median diameter for that stage. The true mass median diameters and true effective cut-off diameters for each stage and for each aerosol have been calculated also. The latter are shown to be superior for interpreting impactor data
The particulate state of fission products released from irradiated uranium when heated in air by John C Gallimore( Book )

2 editions published in 1963 in English and held by 2 WorldCat member libraries worldwide

A gamma ray detector of variable geometry for whole body counting of small animals by R. M Goodrich( Book )

2 editions published in 1964 in English and held by 2 WorldCat member libraries worldwide

Data procurement and processing for the fission product inhalation program using an automatic read out counting system by R. M Goodrich( Book )

2 editions published in 1963 in English and held by 2 WorldCat member libraries worldwide

Data processing primarily concerned with studying experimentally the distribution and excretion of inhaled mixed fission products, has been "streamlined" and automated considerably. An automatic read out counting system is in use which allows the radioactivity information from the scaling system to be transmitted directly to punch tape and/or type- writer. Additional sample information, such as tissue identification and weight, counting time, experiment number, etc., is preset with thumb- wheel switches into a data input box. Read out of the data input box just precedes scaler read out, the signal for which is given by the end of preset counting time. The punched-tape is converted to cards which are stored until completion of an experiment. At this time the information is used in a program to compute the necessary parameters for final distribution and excretion analysis. When desired, the computer plots the radioactivity data from any given series of tissue or whole body determinations and yields the constants of the least squares equations. Integration of the function may also be performed for dosage determination
Procedures and equipment used in inhalation studies on small animals by R. G Thomas( Book )

2 editions published in 1963 in English and held by 2 WorldCat member libraries worldwide

Procedures and equipment used in exposing small animals to aerosols of fission products are described. The exposure chamber with attached plethysmographs for monitoring the respiratory patterns is shown diagrammatically and the operational plan is set forth. Construction criteria for the plethysmographs are also included in detail. The descriptions concerning the animals include specifications on metabolism units and cleaning procedures, whole body counting and somewhat detailed sacrifice and necrotomy procedures
The tissue distribution and excretion of cesium-137 following inhalation : preliminary data for rats by J. F Stara( Book )

2 editions published in 1963 in English and held by 2 WorldCat member libraries worldwide

Data were obtained for the distribution-excretion pattern of cesium in rats over a period of 102 days following inhalation exposure. Three groups of 20 rats each were exposed to aerosols generated from solutions of "carrier- free", 1 and 8 per cent cesium chloride which contained cesium-137 as a tracer. Urine and feces of all rats were collected daily until sacrifice, and the time-tissue distribution patterns were determined after death. All measurements were made by gamma counting with sodium iodide crystals. Cesium chloride, being extremely soluble, was absorbed rapidly from the lungs and the digestive tract and the amount initially deposited in lung was reduced to less than 1 per cent during the first post-exposure day. The initial deposition in the lung was dependent on the aerosol particle size which was varied by the addition of the cesium chloride "carrier"; more lung deposition occurred with the smallest particle sizes. After the first day, the skeletal muscle and skin contained the largest amounts of this fission product but several organs such as lung and kidney had approximately the same concentrations. Because of lack of significant amounts of radioactivity at the later sacrifice times, no definite decision could be made regarding the choice of one "critical" organ for greatest radiation effect
The tissue distribution and excretion of cesium-137 following inhalation : preliminary data for rats by J. F Stara( Book )

1 edition published in 1963 in English and held by 1 WorldCat member library worldwide

Data were obtained for the distribution-excretion pattern of cesium in rats over a period of 102 days following inhalation exposure. Three groups of 20 rats each were exposed to aerosols generated from solutions of "carrier- free", 1 and 8 per cent cesium chloride which contained cesium-137 as a tracer. Urine and feces of all rats were collected daily until sacrifice, and the time-tissue distribution patterns were determined after death. All measurements were made by gamma counting with sodium iodide crystals. Cesium chloride, being extremely soluble, was absorbed rapidly from the lungs and the digestive tract and the amount initially deposited in lung was reduced to less than 1 per cent during the first post-exposure day. The initial deposition in the lung was dependent on the aerosol particle size which was varied by the addition of the cesium chloride "carrier"; more lung deposition occurred with the smallest particle sizes. After the first day, the skeletal muscle and skin contained the largest amounts of this fission product but several organs such as lung and kidney had approximately the same concentrations. Because of lack of significant amounts of radioactivity at the later sacrifice times, no definite decision could be made regarding the choice of one "critical" organ for greatest radiation effect
Annual report by Fission Product Inhalation Program( )

in English and held by 1 WorldCat member library worldwide

Response to secondary antigenic stimulus after whole body X-irradiation in the beagle by F. F Pindak( )

1 edition published in 1964 in English and held by 0 WorldCat member libraries worldwide

The results of the administration to healthy beagles of a secondary antigenic stimulus (booster dose) of Leptospira canicola and infectious canine hepatitis virus (ICH) are reported. Twelve previously vaccinated animals were used. Six were exposed to a 335 r dose of x-irradiation. Three controls and three irradiated dogs received the booster dose two days after the irradiation and the remaining six, seven days after. Agglutinin titres for Leptospira canicola of 1:32 to 1:256 were observed in the 12 beagles before the booster dose. No increases of significance were found in either the controls or the experimental group after the booster dose. Complement fixingtitres for the ICH virus of 1:16 to 1:64 were seen in all animals before revaccination. There was no significant difference in the titres of the control group and the experimental group which were given the ICH booster seven days after irradiation. However, the response observed in the controls given the booster after two days was absent in the irradiated animals
Operating characteristics of the Lauterbach and Dautrebande aerosol generators by Lovelace Foundation for Medical Education and Research( )

1 edition published in 1963 in English and held by 0 WorldCat member libraries worldwide

Ultramicro methods in biochemistry( )

in English and held by 0 WorldCat member libraries worldwide

A battery of biochemical tests to survey the function of body organs and systems of animals under a variety of experimental circumstances was selected. The choice of procedures was guided by an analytical concept, often employed clinically, to reveal early failure of the integrative mechanisms responsible for maintaining homeostasis. More specifically, the methods were chosen to assess general metabolism; to reveal general tissue destruction; and to provide selected data concerning adrenal, thyroid and liver function as well as the status of liver, kidney and bone. The need for serial sampling necessitated the development of an ultramicro system to allow numerous determinations on a small sample of blood. The Sanz ultramicro system was evaluated and various aspects of the associated instrumentation are described and considered. Ultramicro procedures for determining serum bilirubin utilizing both the diazo reaction and spectrophotometric analysis were investigated. The preparation of a bilirubin standard in aqueous protein solution was developed and evaluated for stability and reproducibility. The relevant diazo coupling and spectrophotometric procedures are described and results comparing the two analytical principles are recorded. Various necessary precautions applicable to these methods are set forth and the advantages and disadvantages of each are detailed and discussed
The development of a continuous cell line from normal dog liver and its susceptibility to viruses by F. F Pindak( )

1 edition published in 1963 in English and held by 0 WorldCat member libraries worldwide

A continuous line of cells was developed from a primary culture of new-born dog liver. The cells were inoculated with five types of Coxsackie B virus, three types of poliovirus, nine types of ECHO virus, and six miscellaneous viruses. Nineteen of these produced cytopathic effect without need of adaptation to the cells. One virus became adapted after four passages, one lost its ability to destroy the cells after the first passage and two failed to grow even after several blind passages
On the calibration of cascade impactors by Thomas T Mercer( )

1 edition published in 1963 in English and held by 0 WorldCat member libraries worldwide

The design of a canine inhalation exposure apparatus incorporating a whole body plethysmograph by B. B Boecker( )

1 edition published in 1964 in English and held by 0 WorldCat member libraries worldwide

A whole body plethysmograph has been incorporated in an apparatus for exposing dogs individually to radioactive aerosols. This makes it possible to monitor the dog's respiratory pattern during the exposure without the use of any respiratory masks or valves. After three different transducer systems were evaluated for use with the plethysmograph, the flow rate transducer was chosen for several reasons including the fact that this system produces inspiratory and expiratory flow rate data as well as tidal volume and respiratory rate information. The aerosol is continuously produced and drawn past the dog's nose during the exposure period and provision has been made for quantification of the aerosol in terms of concentration and particle size distribution for each experiment. External contamination of the dog is minimal since only the nostril area is uncovered within the aerosol exposure chamber. Pertinent design and calibration features are discussed
An electrostatic precipitator for the collection of aerosol samples for particle size analysis by Thomas T Mercer( )

1 edition published in 1963 in English and held by 0 WorldCat member libraries worldwide

 
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Alternative Names
Fission Product Inhalation Program

Fission Product Inhalation Project

Lovelace Foundation for Medical Education and Research. Fission Product Inhalation Program

Languages
English (29)