WorldCat Identities

Housman, David E.

Overview
Works: 12 works in 29 publications in 1 language and 410 library holdings
Genres: Conference papers and proceedings  History 
Roles: Editor, Author, Other, htt
Classifications: RC280.N4, 616.99383
Publication Timeline
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Most widely held works by David E Housman
Neurofibromatosis by Bruce R Korf( Book )

10 editions published in 1986 in English and held by 263 WorldCat member libraries worldwide

What little is known about the rare genetic disease popularly but wrongly associated with The Elephant Man, is presented in terms that people with no medical training can decipher, and clinicians can relate to their knowledge. Focuses on the care of the patient with any of a wide range of symptoms, while waiting for the molecular geneticists to track down the gene and figure out how it works
Cancer genes : functional aspects by Enrico Mihich( Book )

4 editions published in 1996 in English and held by 117 WorldCat member libraries worldwide

The seventh Annual Pezcoller Symposium entitled, Cancer Genes: Functional As pects, was held in Trento, Italy, June 14-16, 1995 and was focused on oncogenes func tion, tumor suppressor gene function, transcription regulation, cell cycle progression regulation and apoptosis, and the clinical implications of oncogene function and regula tion for prevention and therapy of cancer. With presentations at the cutting edge of pro gress and stimulating discussions, this Symposium addressed issues related to the mechanisms of control of cell growth and death by certain genes such as c-myc, src, fyns, bcl2, the function of cdk inhibitors, the functions of p53 and WTI, the mechanisms of transcriptional activation of specific oncogenes, the genetic characterization of certain he matological malignancies, the interference with specific sites along signal transduction and the genetic alterations of tumor immunity. We wish to thank the participants in the Symposium for their substantial contribu tions and their participation in the spirited discussions which followed. We would also like to thank Drs. Jane Azizkhan, Paolo Comoglio, Giulio Draetta~ David M. Livingston and Alex Matter for their essential input as members of the Program Committee, and Ms. A. Toscani for her invaluable assistance. The aid of the Bank Cassa di Risparmio di Trento and Rovereto, and the Municipal, Provincial and Regional Administrations in sup porting this Symposium through the Pezcoller Foundation are also acknowledged with deep appreciation. Finally, we wish to thank the staff of Plenum Publishing Corporation for their efficient cooperation in the production of these Proceedings
Promises and perils of genetic testing by Bi-Annual DeVos Medical Ethics Colloquy( Book )

1 edition published in 2014 in English and held by 16 WorldCat member libraries worldwide

Tumor biology : regulation of cell growth, differentiation, and genetics in cancer by Differentiation and Genetics in Cancer" NATO Science Institute"Regulation of Cell Growth( Book )

2 editions published in 1996 in English and held by 3 WorldCat member libraries worldwide

With the aim of providing an international forum for the communication of both the basic and clinical aspects of molecular and cellular biology of cancer, a NATO ASl was held in Porto Carras, Halkidiki, Greece, September 1-12, 1995. The principles as well as recent developments in tumor biology were discussed in depth, with emphasis on the regulation of the cell cycle, differentiation, programmed cell death (apoptosis) and genetics of cancer. This book constitutes the proceedings of that meeting. Specifically, the following areas were addressed: (a) enzymes and proteins (cyclins) that control the cell cycle, as well as the role of m as gene in meiosis and transformation; (b) the structural basis for specificity in protein-tyrosine kinase reactions; (c) the differentiation of normal as well as neoplastic cells with respect to molecular mechanism(s) by which chemical agents or growth factors trigger maturation; (d) phenotypic and genetic aspects of apoptosis; (e) the role of growth factors, like IGF-l, FGF, TN, IL-6, etc. , in cell cycle regulation, apoptosis (cell death) and senescence; (f) molecular mechanisms of transcriptional activation of globin genes and stability of mRNAs related to growth proteins and iron metabolism; (g) the cellular and molecular biology of bone marrow hemopoiesis; and (h) neurotrophic factors and the generation of cellular diversity in the central nervous system. It was obvious from the studies presented that neoplastic cell growth, differentiation and apoptosis in many cell types are regulated at several levels
A Novel Monoallelically Expressed Candidate Tumor Suppressor Gene for Breast Carcingenesis on Chromosome 11p15.5( )

3 editions published between 2000 and 2002 in English and held by 3 WorldCat member libraries worldwide

I have identified a novel Xist-like nuclear transcript (11p-xlnt) which is monoallelically expressed and accumulates in the interphase nucleus at its site of transcription. 11p-xlnt is transcribed from within a narrowly defined 500 kb portion of human chromosome 11p15.5 that exhibits loss of heterozygosity (LOH) in 40% of breast cancers. I have shown that 11p-xlnt is transcribed from within an intron of and antisense to the KvLQT gene and spans at least 40 kb of genomic sequence. Construction and screening of a cDNA library failed to reveal evidence of splicing for this large transcript. while transcription appears to be exclusively from the paternal allele in normal tissues, I have shown that expression occurs from both maternal and paternal alleles in a rhabdomyosarcoma cell line, although expression is found to be monoallelic on a single cell basis by RNA FISH. 11p-xlnt may play a pant in local and regional gene regulation at the imprinted domain on chromosome 11p
The role of methionine in the initiation of protein synthesis by David E Housman( Book )

3 editions published in 1971 in English and held by 2 WorldCat member libraries worldwide

Genetics of Wilms tumor, and insights into responses to chemotherapy by David E Housman( Recording )

1 edition published in 1994 in English and held by 1 WorldCat member library worldwide

First part of lecture covers Wilms tumors, which unlike some other cancers is highly responsive to treatment by radiation and chemotherapy. The latter part of the lecture delves into the topics suggested by the original title for the lecture, on apoptosis and cancer treatment
What if? A world without code Send in the marine ; Heal thyself( Visual )

1 edition published in 2003 in English and held by 1 WorldCat member library worldwide

pt.[1]. What if? A world without code - James Watson and Francis Crick, the co-discoverers of the DNA double helix, changed the world forever when they unveiled their now famous molecular model fifty years ago. Utilizing the data from previous biological research, Watson and Crick conceived a beautiful structure that explained how living things grow. We talk with renowned geneticists and researchers as they discuss the significance of the double helix model, pay tribute to its inventors, and ponder where we might be without this fundamental revelation. - pt.[2]. Send in the marine - We know that the mouse genome, so similar to a human's, is a central component of multiple human-related biological studies. But can sea creatures be helpful research partners, too? In 1998, the Marine Biological Lab sent three toadfish up on the Shuttle Discovery with John Glenn to study the effects of weightlessness and space travel on humans. In our visit to the MBL, we learn that toadfish and people have virtually identical inner ears - one of many examples of a shared evolution found in the marine environment. - pt.[3]. Heal thyself - At the age of three, Kyle Rattray developed a rare child-onset cancer of the kidney called Wilm's tumor. The experience, which he survived, has directed his life toward cancer research. Today, Kyle is a sophomore at MIT, taking biology from Professor Eric Lander and working on a research project in Professor David Housman's lab - research aimed at his own cancer
Neurofibromatosis : Conference : Papers( Book )

1 edition published in 1986 in English and held by 1 WorldCat member library worldwide

Huntington's and haplotypes : meeting the challenges of the genome by David E Housman( Visual )

1 edition published in 2006 in English and held by 1 WorldCat member library worldwide

Control of proliferation and differentiation in cells transformed by Friend virus by David E Housman( Book )

1 edition published in 1980 in English and held by 1 WorldCat member library worldwide

Secrets of the sequence( Visual )

1 edition published in 2002 in English and held by 1 WorldCat member library worldwide

The first segment examines how goat milk can be spun into spider silk five times stronger than steel by breeding goats with spider genes in their mammalian cells. The second segment focuses on the cloning of house pets. The last part of the program features Kyle Rattray, a cancer survivor. He contracted the disease at the age of three, was cured and now devotes his life to cancer research
 
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Languages
English (29)