WorldCat Identities

Rott, R.

Overview
Works: 79 works in 132 publications in 2 languages and 1,878 library holdings
Genres: Conference papers and proceedings  Periodicals 
Roles: Author, Editor, Honoree, Other, Contributor
Publication Timeline
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Most widely held works by R Rott
The Molecular biology of bacterial virus systems( Book )

6 editions published between 1988 and 2013 in English and held by 210 WorldCat member libraries worldwide

The fact that none of the known DNA polymerases is able to initiate DNA chains but only to elongate from a free 3' -OH group raises the problem of how replication is initiated, both at the replication origin and on Okazaki frag­ ments. It was first shown by A. KORNBERG et al. that a general mechanism to initiate replication is through the formation of an RNA primer catalyzed by RNA polymerases or by a new class of enzymes, the primases (KORNBERG 1980). This mechanism, which can be used in the case of circular DNA molecules or linear DNAs that circularize or form concatemers, cannot be used at the ends of linear DNAs since the RNA primer is removed from the DNA chain, and there is no way of filling the gap resulting at the 5' -ends of the newly synthesized DNA chain. In some cases linear DNA molecules contain a palin­ dromic nucleotide sequence at the 3' -end that allows the formation of a hairpin structure which provides the needed free 3'-OH group for elongation. This mechanism, first proposed by CAVALIER-SMITH (1974) for eukaryotic DNA repli­ cation, was shown to take place in several systems (KORNBERG 1980, 1982). Another mechanism to initiate replication consists in the specific nicking of one of the strands of a circular double-stranded DNA, producing a 3'-OH group available for elongation (KORNBERG 1980)
Molecular basis of viral and microbial pathogenesis : 38. Colloquium der Gesellschaft für Biologische Chemie, 9.-11. April 1987 in Mosbach/Baden ; edited by R. Rott and W. Goebel by Gesellschaft für Biologische Chemie( Book )

11 editions published in 1988 in English and held by 208 WorldCat member libraries worldwide

Elucidation of the mechanisms of pathogenesis underlying the diseases caused by viruses and bacteria has fascinated scientists for many years in two ways. Firstly, these pathogenic agents represent relatively sim­ ple biological systems for the study of basic biological processes such as replication, gene regulation, genetic variability and host-pathogen interactions. Secondly, process in this field is valuable in a practi­ cal sence, since it can help in the control of these diseases. The avail­ ability of new genetic and immunological techniques, especially recom­ binant DNA methods and monoclonal antibody technology, has provided powerful tools for unravelling the genetic, biochemical and immunologi­ cal basis of viral and microbial pathogenesis. Molecular cloning has allowed the isolation of single genes or groups of genes related to phenotypes which appear to be immunologically important for pathogene­ sis. The specific elimination of such genes from the complex genomes of the pathogens can now be achieved with similar genetic techniques. These genetic studies have provided additional information on the role played by specific phenotypic traits in pathogenesis, especially when combined with relevant animal model systems. Furthermore, the struc­ tural analysis of important virulence factors and surface antigens may allow the prediction of antigenic domains suitable for the development of new vaccines. The 38th Mosbacher Colloquium focuses on the molecular basis of viral and microbial pathogenesis. The virology part begins with the well­ studied plant viroids. The unusual structure of their genome, as well as knowledge about their replication and pathogenicity, are presented
Modern trends in virology by H Bauer( Book )

3 editions published in 1988 in English and held by 119 WorldCat member libraries worldwide

Current topics in microbiology and immunology( )

2 editions published in 1969 in English and held by 80 WorldCat member libraries worldwide

Current topics in microbiology and immunology by M Cooper( )

4 editions published between 1983 and 1985 in English and held by 75 WorldCat member libraries worldwide

Current topics in microbiology and immunology = Ergebnisse der Mikrobiologie und Immunitätsforschung by W Arber( )

2 editions published in 1975 in English and held by 57 WorldCat member libraries worldwide

The processes involved in herpesvirus replication, latency, and oncogenic transformation, have, in general, been rather poorly defined. A primary reason for this is the size and complexity of the herpesvirus genome. Undoubtedly, a better understanding of the functions of the viral genome in infected and transformed cells will be achieved through studies with temperature-sensitive (ts) mutants of herpesviruses since, theoretically, any essential gene function can be affected by mutants of this type. A. The Herpesviruses A consideration of the genetic analysis of members of the herpesvirus group necessitates a description, albeit brief, of the properties of the group and, most importantly, of their genetic material. The herpesviruses comprise a group of relatively large (100-150 nm), enveloped viruses. The envelope surrounds an icosahedral capsid enclosing a core which contains double­ stranded DNA (ROIZMAN, 1969). The group is thus defined on the basis of a common virion morphology. In addition to a common structure, members of the group share a number of biological properties such as a similar replicative cycle, the ability to cause latent and chronic infections, and the ability to induce antigenic modifications of infected cell membranes. Several herpes­ viruses have been associated recently with malignancies in man and animals (KLEIN, 1972). Herpesviruses are ubiquitous and have been described in over 30 different species (HUNT and MELENDEZ, 1969; WILDY, 1971; FARLEY et aI. , 1972; KAZAMA and SCHORNSTEIN, 1972; NAHMIAS et aI. , 1972; ROlZMAN et aI. , 1973). Their widespread occurrence in nature suggests a common ancestor
Current Topics in Microbiology and Immunology by W Arber( )

1 edition published in 1969 in English and held by 52 WorldCat member libraries worldwide

Molekulare Mechanismen der Variabilität und Evolution von Influenzaviren by R Rott( Book )

3 editions published in 1990 in German and held by 52 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology : Ergebnisse der Mikrobiologie und Immunitätsforschung by W Arber( )

2 editions published in 1968 in English and held by 50 WorldCat member libraries worldwide

Ever since arbovirus infections became known and their relative importance assessed, experiments were designed to elucidate the mode of transmission and the most important natural hosts responsible for perpetuating the infection in nature. Human infections and the disease in wild rodents, birds, and domestic animals were studied in relation to viremia and distribution of the infectious agent in the organism. With increasing epidemiological studies it became apparent that the neural manifestations of the disease are very uncommon, confined only to a small percentage of individuals of the most susceptible species. Various factors have been proposed to explain why in certain instances the virus becomes establish­ ed in the central nervous system and causes a serious or lethal disease. For example, differences in the virulence of the virus strains, varying susceptibility of individuals of one species, or intercurrent circumstances facilitating access of the virus to the central nervous system were alleged. Also, various possible routes of entry of the virus into the brain and spinal cord have been considered
Current topics in microbiology and immunology by A Clarke( )

1 edition published in 1986 in English and held by 50 WorldCat member libraries worldwide

Current topics in microbiology and immunology by W Arber( )

1 edition published in 1970 in English and held by 47 WorldCat member libraries worldwide

The Molecular Biology of Bacterial Virus Systems by G Hobom( )

1 edition published in 1988 in English and held by 47 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology by A Clarke( )

1 edition published in 1986 in English and held by 46 WorldCat member libraries worldwide

Progress in drug research by S Archer( )

2 editions published in 1974 in English and held by 46 WorldCat member libraries worldwide

The present 18th volume differs from previous volumes insofar as, with the exception of two contributions, it is exclusively concerned with problems of a single field, namely Tropical Medicine. This was occasioned by the InternatioƯ nal Symposium on the investigation and treatment of infectious tropical diseases held in Bombay in January 1974 and organized by the editor in collaboration with the Minister of Health of the State of Maharashtra, Dr. Rafiq Zakaria, the Director of the Hafl'kine Institute, Dr. B. Gaitonde, and with Dr. J.N. Banerjee, Dr. S.K. Bhattacharya and Mr. P. D'Souza. The Hafl'kine Institute celebrated on this occasion the 75th year of its existence and everyone entrusted with the organisation of the Symposium considered themselves fortunate to have been able to help in strengthening the contacts between Indian and foreign research workers, in the hope of, in this way, making a contribution to the fight against infectious tropical diseases. The editor hopes that the present 18th volume will represent comprehensive information on the topics treated at the Symposium; the 19th volume, which will soon appear, is concerned with the same area, so that the two volumes together should give a good picture of the many still unsolved problems. The editor would also like to take this opportunity of expressing his gratitude to his collaborator, Dr. A. Niif, who, as usual, performed valuable services in working over the manuscripts
Current topics in microbiology and immunology by Werner Henle( )

1 edition published in 1982 in English and held by 45 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology by W Arber( )

2 editions published in 1974 in English and held by 44 WorldCat member libraries worldwide

Prominent progress in molecular biology was only made when it became possible to separate functionally distinct molecules by taking advantage of their biophysical properties. Likewise, the analysis of the functions of hetero­ geneous populations of immunocompetent cells, as to the functional properties of their various subpopulations, can not be done until these can be isolated in reasonably pure form by selective fractionation. During the last few years significant advances have been made in this field, and cells have been separated according to size, density or charge (MILLER et aI. , 1969; SHORTMAN, 1968; ANDERSSON, 1973 c), or by taking advantage of more specific surface markers to allow selective depletion or enrichment of a given subpopulation of cells (WIGZELL and ANDERSSON, 1971). Although separation techniques have been used in a variety of cellular systems, they have been particularly useful in the study of reticuloendothelial cells and primarily in the study of cells partici­ pating in the immune responses. Quite extensive reviews have been written which well cover the methods used for separation of cells and the results obtained with the various approaches (WIGZELL and ANDERSSON, 1971; SHORTMAN, 1972). To review this work is becoming a more and more voluminous task. As data rapidly accumulate, we will not try to make such a complete review
Current topics in microbiology and immunology : by W Arber( )

3 editions published in 1974 in English and held by 44 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology by W Arber( )

2 editions published in 1976 in English and held by 43 WorldCat member libraries worldwide

Current Topics in Microbiology and Immunology by W Arber( )

1 edition published in 1974 in English and held by 42 WorldCat member libraries worldwide

Current topics in microbiology and immunology by Werner Arber( )

1 edition published in 1973 in English and held by 42 WorldCat member libraries worldwide

 
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WorldCat IdentitiesRelated Identities
Alternative Names
Rott, R. 1926-2003

Rott, R. (Rudolf), 1926-2003

Rott, Rudi 1926-

Rott, Rudi 1926-2003

Rott, Rudolf 1926-

Rudolf Rott deutscher Virologe

Rudolf Rott Duits viroloog (1926-2003)

Rudolf Rott German virologist

Rudolf Rott tysk professor

Languages
English (47)

German (3)