WorldCat Identities

Georgiou, George

Overview
Works: 14 works in 67 publications in 1 language and 1,434 library holdings
Genres: Conference papers and proceedings  Laboratory manuals  Methods (Music)  Pictorial works 
Roles: Editor, Author, Other
Publication Timeline
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Most widely held works by George Georgiou
Protein refolding by George Georgiou( Book )

17 editions published in 1991 in English and held by 395 WorldCat member libraries worldwide

Inclusion bodies and recovery of proteins from the aggregated state. (Eliana De Bernardez-Clark and George Georgiou). Physical methods and models for the study of protein aggregation. (Catherine H. Schein). Mechanisms of inclusion body formation. (Anna Mitraki, Cameron Haase-Pettingell, and Jobathan King). Structure and stability of cytochrome e folding intermediates. (Gulnur A. Elove and Heinrich Roder). Thermostability of drifted oligomeric, reduced, and refolded proteins. (S.L. Sagar and M.M.Domach). Oxidative refolding of recombinant human glia maturation factor beta. (Asgar Zaheer and Ramon Lim). Limited proteolysis of solvent-induced folding changes of B-Lactoglobulin. (M. Dalgalarrondo, C. Bertrand-Harb, J.-M. Chobert, E. Dufour, and T. Haertlé). Folding and aggregation of RTEM B-Lactamase. (Pascal Valax and George Georgiou). Role of chaperonins in protein folding. (Pierre Goloubinoff, Anthony A. Gatenby, and George H. Lorimer). Pathway for the thermal unfolding of wild type and mutant forms of the thermostable P22 tailspike endorhamnosidase. (Bao-lu Chen and Jayanthi Reddy). Active creatine kinase refolded from inclusion bodies in Escherichia coli: improved recovery by removal of contaminating protease. (Patrícia C. Babbitt, Brian L. West, Douglas D. Buechter, Lorenzo H. Chen, Irwin D. Kuntz, and George L. Kenyon). Equilibrium Association of a molten globule intermediate in the refolding of bovine carbonic anhydrase. (Jefrey L. Cleland and Daniel I. C. Wang). An engineering approach to achieving high-protein refolding yields. (Steven Vicik and Eliana De Bernardez-Clark). Commercial-scale refolding of recombinant methionyl bovine somatotropin. (S. Bradley Storrs and Todd M. Przybycien). Large-scale refolding of secretory leukocyte protease inhibitor. (Robert J. Seely and Mark D. Young)
Directed enzyme evolution : screening and selection methods by Frances Hamilton Arnold( )

14 editions published between 2003 and 2010 in English and held by 345 WorldCat member libraries worldwide

Directed evolution, the application of evolutionary design to enzyme engineering, requires effective screening strategies to isolate those proteins that perform a desired function from the libraries generated by the techniques. In Directed Enzyme Evolution: Screening and Selection Methods, seasoned practitioners from many leading laboratories describe their leading and readily reproducible screening strategies for isolating useful clones. These techniques have been optimized for sensitivity, high throughput, and robustness, and are of proven utility for directed evolution purposes. The assays presented use a variety of techniques, including genetic complementation, microtiter plates, solid-phase screens with colorimetric substrates, and flow cytometric screens. There are also representative examples of how phage libraries may be interrogated for enzymatic activity. Each protocol contains detailed step-by-step instructions and many notes on how best to deal with the problems that may occur. An accompanying volume, Directed Evolution Library Creation: Methods and Protocols (ISBN 1-58829-285-1), describes readily reproducible methods for the creation of mutated DNA molecules and DNA libraries. Taken together, Directed Enzyme Evolution: Screening and Selection Methods and Directed Evolution Library Creation: Methods and Protocols capture for newcomers and more experienced investigators alike all the key methods for using directed protein evolution to better understand protein structure-function relationships, to discover new enzymes and therapeutic proteins, and to design new assays suitable for specific applications
Directed evolution library creation : methods and protocols by Frances Hamilton Arnold( )

12 editions published in 2003 in English and held by 343 WorldCat member libraries worldwide

Directed protein evolution-a powerful technique for the discovery of new enzymes and therapeutic proteins-has matured to the point that it is now the centerpiece of enzyme engineering, where it has catalyzed the development of numerous experimental methods. In Directed Evolution Library Creation: Methods and Protocols, seasoned practitioners from many leading laboratories share their best experimental protocols for the generation of molecular diversity. Described in step-by-step detail to ensure experimental success, these protocols include readily reproducible methods for random mutagenesis of entire genes or segments of genes, for homologous and nonhomologous recombination, and for constructing in vivo libraries in bacteria and yeast. In addition to the various protocols for creating libraries, this volume also describes ways to analyze libraries, particularly those made by recombination. An accompanying volume, Directed Enzyme Evolution: Screening and Selection Methods (ISBN: 1-58829-286-X), is devoted entirely to selection and screening methods that can be applied to the directed evolution of enzymes. Taken together, Directed Evolution Library Creation: Methods and Protocols and Directed Enzyme Evolution: Screening and Selection Methods capture for newcomers and more experienced investigators alike all the key methods for using directed protein evolution to better understand protein structure-function relationships, to discover new enzymes and therapeutic proteins, and to design new assays suitable for specific applications
Biocatalyst design for stability and specificity by Chemical Congress of North America( Book )

7 editions published between 1991 and 1993 in English and held by 38 WorldCat member libraries worldwide

Microbial enhanced oil recovery research by M. M Sharma( Book )

2 editions published in 1993 in English and held by 5 WorldCat member libraries worldwide

Development of glass reinforced hydroxyapatite for hard tissue surgery by George Georgiou( Book )

4 editions published in 2002 in English and held by 4 WorldCat member libraries worldwide

Structure, function, and engineering of disulfide bond isomerization in Escherichia coli by Laura Segatori( )

1 edition published in 2005 in English and held by 3 WorldCat member libraries worldwide

Engineering highly active enzymes with altered substrate selectivities by Karl Edwin Griswold( )

1 edition published in 2005 in English and held by 3 WorldCat member libraries worldwide

Functional and structural studies of protein inhibitors of RNase E activity that globally modulate mRNA abundance in Escherichia coli by Junjun Gao( )

1 edition published in 2005 in English and held by 3 WorldCat member libraries worldwide

Biocatalyst design for stability and specificity( )

1 edition published in 1993 in English and held by 2 WorldCat member libraries worldwide

Fault lines : Turkey from East to West by George Georgiou( Book )

1 edition published in 2010 in English and held by 2 WorldCat member libraries worldwide

Directed Evolution Library Creation : Methods and Protocols. Methods in Molecular Biology, Volume 231( )

1 edition published in 2003 in English and held by 1 WorldCat member library worldwide

Directed protein evolution-a powerful technique for the discovery of new enzymes and therapeutic proteins-has matured to the point that it is now the centerpiece of enzyme engineering, where it has catalyzed the development of numerous experimental methods. In Directed Evolution Library Creation: Methods and Protocols, seasoned practitioners from many leading laboratories share their best experimental protocols for the generation of molecular diversity. Described in step-by-step detail to ensure experimental success, these protocols include readily reproducible methods for random mutagenesis of entire genes or segments of genes, for homologous and nonhomologous recombination, and for constructing in vivo libraries in bacteria and yeast. In addition to the various protocols for creating libraries, this volume also describes ways to analyze libraries, particularly those made by recombination. An accompanying volume, Directed Enzyme Evolution: Screening and Selection Methods (ISBN: 1-58829-286-X), is devoted entirely to selection and screening methods that can be applied to the directed evolution of enzymes. Taken together, Directed Evolution Library Creation: Methods and Protocols and Directed Enzyme Evolution: Screening and Selection Methods capture for newcomers and more experienced investigators alike all the key methods for using directed protein evolution to better understand protein structure-function relationships, to discover new enzymes and therapeutic proteins, and to design new assays suitable for specific applications
 
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Directed evolution library creation : methods and protocols
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Directed evolution library creation : methods and protocolsFault lines : Turkey from East to West
Languages
English (67)