WorldCat Identities

Scheper, Thomas

Overview
Works: 108 works in 193 publications in 2 languages and 1,437 library holdings
Roles: Author, dgs, Editor, Creator, Contributor, Other
Publication Timeline
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Most widely held works by Thomas Scheper
Modern biochemical engineering by A Fiechter( )

13 editions published between 1992 and 2013 in English and German and held by 193 WorldCat member libraries worldwide

New enzymes for organic synthesis : screening, supply and engineering by Thomas Scheper( )

8 editions published between 1997 and 1999 in English and German and held by 139 WorldCat member libraries worldwide

Isolated enzymes are known as useful for synthesising of complex molecules with more and more large scale applications in recent years. These six reviews show different steps in the development of enzymatic syntheses for useful compounds. Screening of novel enzymes, their biochemical characterisation as well as reaction engineering approaches in order to increase their performance are treated in three papers. Then the use of protein design as a tool for the directed improvement of reactivity and selectivity of biocatalysts is described in two reviews. The supply of sufficient quantities of biocatalysts must not be neglected: fluidized bed adsorption as an emerging technology for the simple and fast purification of biomolecules is presented in the light of its potential in large scale supply of enzyme catalysts
Biotreatment, downstream processing, and modelling by Thomas Scheper( )

3 editions published between 1997 and 2013 in English and held by 113 WorldCat member libraries worldwide

Bioprocess and algae reactor technology, apoptosis( )

4 editions published between 1998 and 2013 in English and held by 92 WorldCat member libraries worldwide

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Tools and applications of biochemical engineering science by K Schügerl( )

4 editions published in 2002 in English and held by 79 WorldCat member libraries worldwide

This volume presents 12 comprehensive and timely review articles on some of the new tools and applications of biochemical engineering and biotechnology. The tools range from screening methods for novel biocatalysts and products, fluorescence spectroscopy and mass spectrometry for monitoring and analysis of cellular processes via mathematical models and protein expression systems for metabolic engineering to new bioreaction and separation devices. The applications cover the uses of animal and tissue cultures, insect cells, recombinant and marine microorganisms for the production of a variety of important bioproducts
Bioanalytik : Messung des Zellzustands und der Zellumgebung in Bioreaktoren by Thomas Scheper( Book )

5 editions published in 1991 in German and held by 60 WorldCat member libraries worldwide

Thermal biosensors, bioactivity, bioaffinity by P. K Bhatia( )

5 editions published between 1999 and 2013 in English and held by 37 WorldCat member libraries worldwide

The immobilized biocatalyst (IMB) is a key component of biotransformation systems that are used to transform substrates to desired products. The impro- ment of biocatalyst properties has a direct influence on the overall effectiveness of the process based on the biotransformation. The basic catalytic characte- stics of biocatalyst that are followed include kinetic properties, pH optima, stability,and inhibition. The investigation of catalytic properties of immobilized enzymes is still a time consuming procedure and is not always simple. In the 1980s,a major effort was made to standardize the rules by which IMB is char- terized. The Working Party of EFB on immobilized biocatalysts has formul- ed principles of individual methods, among them the requirement of kinetic characterization [1]. It was recommended to use a packed-bed reactor,equipped with temperature control and with infinite flow circulation. The system should be equipped with a post-column unit to measure the time-dependence of the product or substrate concentration [2, 3], the most commonly used analytical methods being spectrophotometry, chemiluminiscence, automatic titration, bioluminiscence, chromatography, polarimetry, and biosensors based on the oxygen electrode. There are two main drawbacks to the application of these methods: 1. The need to vary the analytical principles, depending on the chemical and physical-chemical properties of analytes; 2. In some cases, mainly in the study of hydrolytic enzymes, the natural s- strate must be replaced by an artificial one,that is chromolytic,chromogenic, chemiluminiscent,bioluminiscent,or fluorescent
New products and new areas of bioprocess engineering by Thomas Scheper( )

3 editions published in 2000 in English and held by 32 WorldCat member libraries worldwide

Today, ergot alkaloids have found widespread clinical use and more than 50 formulations contain natural or semisynthetic ergot alkaloids. They are used in the treatment of uterine atonia, postpartum bleeding, migraine, orthostatic circulatory disturbances, senile cerebral insufficiency, hypertension, hyp- prolactinemia, acromegaly, and Parkinsonism. Recently, new therapeutic - plications have emerged, e.g., against schizophrenia and for therapeutic usage based on newly discovered antibacterial and cytostatic effects,immunomodu- tory and hypolipemic activity.The broad physiological effects of ergot alkaloids are based mostly on their interactions with neurotransmitter receptors on the cells. The presence of "hidden structures'' resembling some important neu- humoral mediators (e.g., noradrenaline, serotonin, dopamine) in the molecules of ergot alkaloids could explain their interactions with these receptors [1]. Ergot alkaloids are produced by the filamentous fungi of the genus, Claviceps (e.g., Claviceps purpurea - Ergot, Mutterkorn). On the industrial scale these alkaloids were produced mostly by parasitic cultivation (field production of the ergot) till the end of the 1970s. Today this uneconomic method has been - placed by submerged fermentation. Even after a century of research on ergot alkaloids the search still continues for new, more potent and more selective ergot alkaloid derivatives
Tools and Applications of Biochemical Engineering Science by K Schügerl( )

1 edition published in 2002 in English and held by 27 WorldCat member libraries worldwide

This special volume "Tools and Applications of Biochemical Engineering Science" is dedicated to Professor Wolf-Dieter Deckwer on the occasion of his 60th bir- day. It was a great pleasure for me to act together with Professor Karl Schtigerl as volume editor and to present here a collection of 11 outstanding review articles written mainly by former students, associates, colleagues and friends of Wolf- Dieter Deckwer. The title of this special volume well reflects the research interests and sci- tific pursuit of Wolf-Dieter Deckwer during his more than 20 years’ work in the area of biochemical engineering, particularly during the last 15 years when he was the head of the Biochemical Engineering Division of GBF (German Nat- nal Research Center for Biotechnology). He has decisively pushed the devel- ment not only of "software tools" ranging from analytical means and mathe- tical models for monitoring and understanding cellular processes to gene expression systems for designing microorganisms, but also of "hardware tools" such as computer control systems, bioreaction and separation devices for eff- tively producing a variety of bioproducts on semi-production scale. New developments in some of these important tools in biochemical engineering are reviewed in articles included in this volume. Wolf-Dieter Deckwer was among the leading biochemical engineers who timely pointed out the necessity of applying these tools in an integrated manner for bioprocess development. By establishing "Integrated Bioprocess Development" as one of the GBF main - search topics as early as 1990 he also actively promoted this idea
Bioreactor systems for tissue engineering by Thomas Scheper( )

5 editions published in 2009 in English and Undetermined and held by 25 WorldCat member libraries worldwide

The editors of this special volume would first like to thank all authors for their excellent contributions. We would also like to thank Prof. Dr. Thomas Scheper, Dr. Marion Hertel and Ulrike Kreusel for providing the opportunity to compose this volume and Springer for organizational and technical support. Tissue engineering represents one of the major emerging fields in modern b- technology; it combines different subjects ranging from biological and material sciences to engineering and clinical disciplines. The aim of tissue engineering is the development of therapeutic approaches to substitute diseased organs or tissues or improve their function. Therefore, three dimensional biocompatible materials are seeded with cells and cultivated in suitable systems to generate functional tissues. Many different aspects play a role in the formation of 3D tissue structures. In the first place the source of the used cells is of the utmost importance. To prevent tissue rejection or immune response, preferentially autologous cells are now used. In particular, stem cells from different sources are gaining exceptional importance as they can be differentiated into different tissues by using special media and supplements. In the field of biomaterials, numerous scaffold materials already exist but new composites are also being developed based on polymeric, natural or xenogenic sources. Moreover, a very important issue in tissue en- neering is the formation of tissues under well defined, controlled and reprod- ible conditions. Therefore, a substantial number of new bioreactors have been developed
Bioprocess and Algae Reactor Technology, Apoptosis by Thomas Scheper( )

1 edition published in 2006 in English and held by 21 WorldCat member libraries worldwide

Biotreatment, Downstream Processing and Modelling by Thomas Scheper( )

1 edition published in 2006 in English and held by 21 WorldCat member libraries worldwide

New Enzymes for Organic Synthesis : Screening, Supply and Engineering by Thomas Scheper( )

1 edition published in 2007 in English and held by 21 WorldCat member libraries worldwide

Modern biochemical engineering : dedicated to Prof. Karl Schügerl on the occasion of his 65th birthday ; with 27 tables( Book )

1 edition published in 1992 in English and held by 20 WorldCat member libraries worldwide

Messung zellinterner und zellexterner Parameter zur Fermentationskontrolle by Thomas Scheper( )

5 editions published in 1985 in German and held by 20 WorldCat member libraries worldwide

Concepts for the implementation of physiologic conditions for the cultivation of human mesenchymal stem cells by Dominik Egger( )

2 editions published in 2017 in English and held by 17 WorldCat member libraries worldwide

Mesenchymal stem cells, 3D, dynamic cultivation, physiologic conditions, hypoxia. - Mesenchymale Stammzellen, dynamische Kultivierung, physiologische Bedingungen, Hypoxie
Aptamer-based optical biosensors by Katharina Urmann( )

2 editions published in 2016 in English and held by 16 WorldCat member libraries worldwide

Optical biosensor, aptamer, label-free, porous silicon. - Optischer Biosensor, markierungsfrei, poröses Silizium
Biokatalytische Gewinnung von Flavonoiden by Anne Schmidt( )

2 editions published in 2011 in German and held by 16 WorldCat member libraries worldwide

Flavonoide, Naringenin, Phloretin, E. ramulus, Biokatalyse, Phloretinhydrolase (PhH), Chalconisomerase (CHI). - Flavonoids, biocatalysis, phloretin hydrolase, chalcone isomerase
Nanocrystalline materials for (solar) photoelectrochemical water splitting by Maryam Jami( )

2 editions published in 2017 in English and held by 16 WorldCat member libraries worldwide

Water splitting, photocatalysis, hydrogen production, water oxidation, hematite, pyrite. - Wasserspaltung, Photokatalyse, Wasserstoffproduktion, Wasseroxidation, Hämatit, Pyrit
Laser flash photolysis and EPR spectroscopy investigaions of bare and lanthanum doped NaTaO3 powders by María Pilar Esteban Mollá( )

2 editions published in 2016 in English and held by 16 WorldCat member libraries worldwide

Sodium tantalate, photocatalysis, laser flash photolysis, trapped charge carriers, EPR. - Natriumtantalat, Photokatalyse, Laser Blitz Photolyse, getrappte Ladungsträger
 
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Audience Level
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  Kids General Special  
Audience level: 0.75 (from 0.51 for Bioreactor ... to 0.93 for New Enzyme ...)

New enzymes for organic synthesis : screening, supply and engineering
Covers
Biotreatment, downstream processing, and modellingBioprocess and algae reactor technology, apoptosisTools and applications of biochemical engineering scienceThermal biosensors, bioactivity, bioaffinityNew products and new areas of bioprocess engineeringBioreactor systems for tissue engineering
Alternative Names
Scheper, T.

Scheper, T. (Thomas)

Scheper, Thomas.

Scheper, Thomas-Helmut 1956-

Languages
English (55)

German (14)