Jung, Hack Sung

Amelioration of High Fat Diet-induced Glucose Intolerance by Blockade of Smad4 in Pancreatic Beta-Cells( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

MEASUREMENT OF SEAWARD GROUND DISPLACEMENTS ON COASTAL LANDFILL AREA USING RADAR INTERFEROMETRY by W.-K Baek( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Erratum to: Proton-hole and core-excited states in the semi-magic nucleus 131In82 by J Taprogge( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Subclinical thyroid dysfunction, bone mineral density, and osteoporosis in a middle-aged Korean population by K Lee( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

IMPROVEMENT OF FOREST FIRE DETECTION ALGORITHM USING BRIGHTNESS TEMPERATURE LAPSE RATE CORRECTION IN HIMAWARI-8 IR CHANNELS: APPLICATION TO THE 6 MAY 2017 SAMCHEOK CITY, KOREA by S. H Park( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Formation and distribution of manganese nodule deposit in the northwestern margin of Clarion-Clipperton fracture zones, northeast equatorial Pacific by K. S Jeong( )

1 edition published in 1996 in English and held by 2 WorldCat member libraries worldwide

An Explanation for How FGFs Predict Species-Specific Tooth Cusp Patterns( )

in English and held by 1 WorldCat member library worldwide

Species-specific cusp patterns result from the iterative formation of enamel knots, the epithelial signaling centers, at the future cusp positions. The expressions of fibroblast growth factors (FGFs), especially Fgf4, in the secondary enamel knots in the areas of the future cusp tips are generally used to manifest the appearance of species-specific tooth shapes. However, the mechanism underlying the predictive role of FGFs in species-specific cusp patterns remains obscure. Here, we demonstrated that gerbils, which have a lophodont pattern, exhibit a striped expression pattern of Fgf4, whereas mice, which have a bunodont pattern, have a spotted expression pattern, and these observations verify the predictive role of Fgf4 in species-specific cusp patterns. By manipulating FGFs' signaling in the inner dental epithelium of gerbils, we provide evidence for the intracellular participation of FGF signaling, specifically FGF4 and FGF20, in Rac1- and RhoA-regulated cellular geometry remolding during the determination of different cusp patterns. Our study presents a novel explanation of how different FGF expression patterns produce different cusp patterns and implies that a conserved intracellular FGF-GTPase signaling module might represent an underlying developmental basis for evolutionary changes in cusp patterns

Alteration of Conserved Alternative Splicing in AMELX Causes Enamel Defects( )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

Tooth enamel is the most highly mineralized tissue in vertebrates. Enamel crystal formation and elongation should be well controlled to achieve an exceptional hardness and a compact microstructure. Enamel matrix calcification occurs with several matrix proteins, such as amelogenin, enamelin, and ameloblastin. Among them, amelogenin is the most abundant enamel matrix protein, and multiple isoforms resulting from extensive but well-conserved alternative splicing and postsecretional processing have been identified. In this report, we recruited a family with a unique enamel defect and identified a silent mutation in exon 4 of the AMELX gene. We show that the mutation caused the inclusion of exon 4, which is almost always skipped, in the mRNA transcript. We further show, by generating and characterizing a transgenic animal model, that the alteration of the ratio and quantity of the developmentally conserved alternative splicing repertoire of AMELX caused defects in enamel matrix mineralization

Phylogenetic analysis of Xylaria based on nuclear ribosomal ITS1-5.8S-ITS2 sequences by Jin Sung Lee( Book )

1 edition published in 2000 in English and held by 1 WorldCat member library worldwide