WorldCat Identities

Dykens, Elisabeth M.

Overview
Works: 14 works in 31 publications in 3 languages and 568 library holdings
Genres: Academic theses 
Roles: Author
Classifications: RC570.2, 616.8588042
Publication Timeline
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Most widely held works by Elisabeth M Dykens
Genetics and mental retardation syndromes : a new look at behavior and interventions by Elisabeth M Dykens( Book )

10 editions published between 2000 and 2005 in English and held by 307 WorldCat member libraries worldwide

Behavior and development in fragile X syndrome by Elisabeth M Dykens( Book )

7 editions published in 1994 in English and held by 233 WorldCat member libraries worldwide

Ritardo mentale : sindromi a base genetica : nuove prospettive nella comprensione del comportamento e nell'intervento by Elisabeth M Dykens( Book )

3 editions published between 2002 and 2003 in Italian and held by 9 WorldCat member libraries worldwide

Development and psychopathology in fragile X syndrome by Elisabeth M Dykens( Book )

1 edition published in 1994 in English and held by 4 WorldCat member libraries worldwide

Behaviour and development in genetic mental retardation syndromes by Elisabeth M Dykens( Book )

1 edition published in 2000 in English and held by 4 WorldCat member libraries worldwide

Intellectual disabilities : genetics, behaviour, and inclusion by Jean Rondal( Book )

1 edition published in 2004 in English and held by 3 WorldCat member libraries worldwide

Effects of MetAP2 inhibition on hyperphagia and body weight in Prader-Willi syndrome: A randomized, double-blind, placebo-controlled trial( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Abstract : Aims: There are no treatments for the extreme hyperphagia and obesity in Prader-Willi syndrome (PWS). The bestPWS clinical trial assessed the efficacy, safety and tolerability of the methionine aminopeptidase 2 (MetAP2) inhibitor, beloranib. Materials and Methods: Participants with PWS (12-65 years old) were randomly assigned (1:1:1) to biweekly placebo, 1.8 mg beloranib or 2.4 mg beloranib injection for 26 weeks at 15 US sites. Co-primary endpoints were the changes in hyperphagia [measured by Hyperphagia Questionnaire for Clinical Trials (HQ-CT); possible score 0-36] and weight by intention-to-treat.ClinicalTrials.gov registration: NCT02179151. Results: One-hundred and seven participants were included in the intention-to-treat analysis: placebo ( n = 34); 1.8 mg beloranib ( n = 36); or 2.4 mg beloranib ( n = 37). Improvement (reduction) in HQ-CT total score was greater in the 1.8 mg (mean difference −6.3, 95% CI −9.6 to −3.0; P = .0003) and 2.4 mg beloranib groups (−7.0, 95% CI −10.5 to −3.6; P = .0001) vs placebo. Compared with placebo, weight change was greater with 1.8 mg (mean difference − 8.2%, 95% CI −10.8 to −5.6; P < .0001) and 2.4 mg beloranib (−9.5%, 95% CI −12.1 to −6.8; P < .0001). Injection site bruising was the most frequent adverse event with beloranib. Dosing was stopped early due to an imbalance in venous thrombotic events in beloranib-treated participants (2 fatal events of pulmonary embolism and 2 events of deep vein thrombosis) compared with placebo. Conclusions: MetAP2 inhibition with beloranib produced statistically significant and clinically meaningful improvements in hyperphagia-related behaviours and weight loss in participants with PWS. Although investigation of beloranib has ceased, inhibition of MetAP2 is a novel mechanism for treating hyperphagia and obesity
Felicidad, bienestar y puntos fuertes del carácter resultados para familias y hermanos /as de personas con retraso mental by Elisabeth M Dykens( )

in Spanish and held by 1 WorldCat member library worldwide

Personality and motivational differences in persons with mental retardation by Elisabeth M Dykens( )

1 edition published in 2001 in English and held by 1 WorldCat member library worldwide

This book presents the most comprehensive review of research regarding personality and motivational differences in persons with mental retardation. From the personal commentary of Edward Zigler, H. Carl Haywood, and Harvey N. Switzky, the book summarizes the classical work of the Yale and Peabody-Vanderbilt School over the last 40 years. A sampling of new directions in research is provided, including work on self-determination theory and practice; decision making; direct and indirect effects of genetic mental retardation syndromes on personality; personality and psychopathology in genetic mental retardation syndromes; a new theory of information processing linking cognition, motivation, and performance; and a sensitivity theory of motivation. This definitive work presents older and evolving newer models and applications to the field in order to demonstrate the power of motivational variables in understanding the behavior of persons with mental retardation. The purpose is to enhance the quality of life in persons with mental retardation and other developmental disabilities
Special issue on behavioral phenotypes( )

1 edition published in 2001 in English and held by 1 WorldCat member library worldwide

Participation - imitation - repetition : treatment techniques with multiply-handicapped autistic children in a water play setting by Elisabeth M Dykens( Book )

1 edition published in 1979 in English and held by 1 WorldCat member library worldwide

Familial and developmental contributions to to [sic] bulimia by Elisabeth M Dykens( )

1 edition published in 1985 in English and held by 1 WorldCat member library worldwide

Antecedents and correlates of bulimia by Elisabeth M Dykens( )

1 edition published in 1983 in English and held by 1 WorldCat member library worldwide

Investigating Self-Concept of Individuals with Prader-Willi Syndrome Psychopathological Beginnings for Populations with Intellectual Disabilities by Honora Einhorn( )

1 edition published in 2013 in English and held by 1 WorldCat member library worldwide

 
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Genetics and mental retardation syndromes : a new look at behavior and interventions Behaviour and development in genetic mental retardation syndromes
Covers
Behaviour and development in genetic mental retardation syndromesIntellectual disabilities : genetics, behaviour, and inclusionPersonality and motivational differences in persons with mental retardation
Languages