WorldCat Identities

Frey, Tom

Overview
Works: 6 works in 6 publications in 2 languages and 58 library holdings
Genres: Catalogs  History 
Classifications: NK9509.65.U6, 688.720973075
Publication Timeline
Key
Publications about  Tom Frey Publications about Tom Frey
Publications by  Tom Frey Publications by Tom Frey
Most widely held works by Tom Frey
Toy Bop! : kid classics of the 50's & 60's by Tom Frey ( Book )
1 edition published in 1994 in English and held by 50 WorldCat member libraries worldwide
Describes toys from the 1950' and 60's and includes photos of some the toys from those years as well as manufacturers
50 Gegenstände als Schreib- und Spreichanlässe : Mittelstufe by Romana Leuzinger ( Book )
1 edition published in 2006 in German and held by 4 WorldCat member libraries worldwide
Using firefighting skills in the Somalian relief effort by Tom Frey ( )
1 edition published in 1993 in English and held by 1 WorldCat member library worldwide
Line-Shape Analysis of NMR Difference Spectra of an Anti-Spin-Label Antibody ( Book )
1 edition published in 1988 in English and held by 1 WorldCat member library worldwide
Specifically deuteriated Fab fragments of the anti-spin-label antibody AN02 were prepared. NMR difference spectra were obtained, in which the spectrum of Fab with some fraction of the binding sites occupied with spin-label hapten was subtracted from the spectrum of Fab with no spin-label. The peak heights were analyzed as a function of the fractional occupation of the binding site, using a computer program that calculates a best fit to the observed spectra. This method treats all of the peaks in the spectra simultaneously. Analyzing all peaks at once allows for the interdependencies in the spectra arising from overlap of positive and negative signals from different peaks. The fitting program calculates line widths for the peaks arising from protons in the binding site region. Almost all of the line widths calculated for the spectrum of the Fab complex with diamagnetic hapten dinitrophenyldiglycine were found to be narrower than the line widths of the corresponding resonances in the spectrum of Fab with an empty binding site. The distances of the binding site region protons from the unpaired electron of the hapten were also obtained from this calculation. Two tyrosine protons were found to be close (<7 A) to this electron. These line-width and distance results are discussed with respect to the structure and dynamics of the antibody binding site. Reprints. (jhd)
Contribution of Tryptophan Residues to the Combining Site of a Monoclonal Anti Dinitrophenyl Spin-Label Antibody ( Book )
1 edition published in 1987 in English and held by 1 WorldCat member library worldwide
Two Fab fragments of the monoclonal anti dinitrophenyl (DNP) spin-label antibody AN02 were prepared by recombination of specifically deuteriated heavy and light chains. In the recombinant H(I)L(II) all the tyrosines and phenylalanines were perdeuteriated as were the tryptophan residues of the heavy chain. In the recombinant H(II)L(I) all the tyrosines and phenylalanines were perdeuteriated as were the tryptophan residues of the light chain. Saturation of three resonances of H(I)L(II), assigned to tryptophan protons of the light chain, resulted in magnetization transfer to the aromatic proton at position 6 of the DNP ring and to the CH2 protons of the glycines linked to the DNP in a diamagnetic hapten (DNP-DG). Saturation of three resonances of H(II)L(I) assigned to tryptophan protons of the heavy chain resulted in magnetization transfer to the CH2 protons of the glycines in DNP-DG. From the dependence of the magnetization transfer on the irradiation time, the cross relaxation rates between the involved protons were estimated. The inferred distances between these protons of the hapten and certain tryptophan protons are 3-4 A. It is concluded that in the combining site of AN02 there is one tryptophan from the light chain and one tryptophan from the heavy chain that are very near the hapten, identified as tryptophan-91 of the light chain and tryptophan-47 of the heavy chain. Reprints. (EDC)
50 Gegestände als Schreib- und Sprechanlässe : Mittelstufe by Romana Leuzinger ( Book )
1 edition published in 2006 in German and held by 1 WorldCat member library worldwide
 
Audience Level
0
Audience Level
1
  Kids General Special  
Audience level: 0.21 (from 0.00 for Contributi ... to 0.47 for 50 Gegenst ...)
Languages
English (4)
German (2)
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