WorldCat Identities

Rappuoli, Rino

Overview
Works: 68 works in 254 publications in 2 languages and 6,926 library holdings
Genres: Handbooks and manuals  Conference papers and proceedings  Software  Lectures 
Roles: Editor, Author, Speaker, htt, Contributor, Other
Classifications: QR175, 571.629
Publication Timeline
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Most widely held works by Rino Rappuoli
Influenza vaccines for the future by Axel Schmidt( )

38 editions published between 2008 and 2011 in English and held by 1,376 WorldCat member libraries worldwide

"The threat constituted by the multiple outbreaks of avian influenza during the last few years is urgently calling for the development of new influenza vaccines. Fortunately, a quantum leap in technology has revolutionized the study of influenza and the engineering of new vaccine strains by reverse genetics. This volume provides a historical background and state-of-the-art information about the recent advances in the biology of influenza and the design of new influenza vaccines."--Jacket
Guidebook to protein toxins and their use in cell biology by Rino Rappuoli( )

19 editions published between 1997 and 2001 in English and held by 1,338 WorldCat member libraries worldwide

Many bacteria, animals, and plants produce toxins that can prove lethal to other organisms. Toxins are a form of "biological warfare" that helps their producer to survive and so confer an evolutionary advantage. They display an extraordinary range of complexity, from the formic acid provided by ants to bacterial proteins composed of thousands of amino acids. This Guidebook considers the more complex protein and peptide toxins and groups them according to their mode of action.; Topics covered include: membrane-permeabilizing toxins; toxins affecting signal transduction and protein synthesis; cytoskeleton-affecting toxins; toxins affecting the immune and inflammatory response. This class of biomolecules will be of interest to a wide range of researchers in cell biology, ; neuroscience, and toxicology
Ranking vaccines : applications of a prioritization software tool by Institute of Medicine (U.S.)( )

3 editions published between 2014 and 2015 in English and held by 1,206 WorldCat member libraries worldwide

SMART Vaccines - Strategic Multi-Attribute Ranking Tool for Vaccines - is a prioritization software tool developed by the Institute of Medicine that utilizes decision science and modeling to help inform choices among candidates for new vaccine development. A blueprint for this computer-based guide was presented in the 2012 report Ranking Vaccines: A Prioritization Framework: Phase I . The 2013 Phase II report refined a beta version of the model developed in the Phase I report. Ranking Vaccines: Applications of a Prioritization Software Tool: Phase III: Use Case Studies and Data Framework extends this project by demonstrating the practical applications of SMART Vaccines through use case scenarios in partnership with the Public Health Agency of Canada, New York State Department of Health, and the Serum Institute of India. This report also explores a novel application of SMART Vaccines in determining new vaccine product profiles, and offers practical strategies for data synthesis and estimation to encourage the broader use of the software
Advanced vaccine research : methods for the decade of vaccines( )

6 editions published in 2015 in English and held by 497 WorldCat member libraries worldwide

Since the first edition of this book, the field of vaccinology has advanced significantly. The application of new sophisticated omics technologies and the use of pioneering approaches have yielded a wealth of new data. This new book aims to distill the most important new findings to provide a timely overview of the field. Written by leading experts in the field, each chapter affords a critical insight to a particular topic, reviews current research, discusses future direction and aims to stimulate discussion
Replicating vaccines : a new generation by Philip R Dormitzer( )

13 editions published between 2010 and 2011 in English and held by 429 WorldCat member libraries worldwide

Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines. Historically, live vaccines have been either directly derived from a natural source or attenuated by empirical approaches using serial passages and host cell adaptation. Currently, we are witnessing a quantum leap in our technological capabilities to specifically modify the genetic make-up of viruses and bacteria, making it possible to generate improved live vaccines and to develop completely new types of replicating vaccines, such as vectored vaccines, single-round infectious vaccines and replicon vaccines. This book highlights some of the most exciting recent developments towards a new generation of replicating vaccines
Antibodies for infectious diseases( )

9 editions published in 2015 in English and held by 352 WorldCat member libraries worldwide

Provides a broad survey across important aspects for understanding mechanisms of immunity to infectious disease, including general features of antibodies and approaches to antibody discovery, individual chapters highlighting antibodies against particular pathogens, and state-of-the-art technical advances and expression systems
Protein and sugar export and assembly in gram-positive bacteria( )

16 editions published between 2017 and 2018 in English and German and held by 294 WorldCat member libraries worldwide

This book focuses on the envelope of Gram-positive bacteria including its composition, the latest discoveries in the mechanisms behind its assembly, and its role in pathogenesis. Furthermore, new applications in biotechnology and vaccine development involving these bacteria are discussed in detail. This concise volume consists of eleven chapters by prominent experts in the field, which review the latest findings and current state of knowledge on a range of diverse yet interlinked aspects. This book is written for all researchers, clinicians and technicians engaged in basic or applied science projects on Gram-positive bacteria
Staphylococcus aureus : microbiology, pathology, immunology, therapy, and prophylaxis by Fabio Bagnoli( )

13 editions published between 2017 and 2018 in English and held by 293 WorldCat member libraries worldwide

"This volume offers a comprehensive overview of basic and applied aspects of Staphylococcus aureus, which is one of the most important human pathogens. It includes sixteen chapters that address the microbiology and immunology of S. aureus, the pathology of its key manifestations, and the current standard of care. Further, it reviews cutting-edge advances in alternative therapeutic and prophylactic approaches to antibiotics."--Publisher's description
Three dimensional human organotypic models for biomedical research by Fabio Bagnoli( )

7 editions published in 2021 in English and held by 184 WorldCat member libraries worldwide

"This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab."--Back cover
Signal transduction and bacterial virulence by Rino Rappuoli( )

9 editions published between 1995 and 2013 in English and German and held by 171 WorldCat member libraries worldwide

In order to survive, bacteria must constantly monitor their structure and physiology. Adaptive behaviours are established by using environmental sensors and response regulators. These communication modules regulate a wide variety of signals including host detection and invasion, cell cycle, metabolite utilization, starvation and many others. The purpose of this volume is to give an overview of the various systems and to introduce recent advances in understanding selected systems of pathogenic bacteria
Cellular microbiology by Pascale Cossart( )

5 editions published between 2000 and 2005 in English and held by 168 WorldCat member libraries worldwide

The term "cellular microbiology" was coined in 1996 to identify an emerging discipline integrating the fields of cell biology and microbiology. The advent of genomics, proteomics, and postgenomics has resulted in more widespread understanding of the field of cellular microbiology among scientists. Cellular Microbiology, 2nd Edition, considers genomic information and advances in technology in an updated examination of this burgeoning area of important research
Vaccine design : innovative approaches and novel strategies( Book )

11 editions published in 2011 in English and held by 132 WorldCat member libraries worldwide

In this book, expert international authors critically review the current cutting-edge research in vaccine design and development. Particular emphasis is given to new approaches and technologies. The book has been divided into two parts. The first part reviews the technologies and approaches used to identify, generate and test new vaccines. Topics include: new strategies to identify protective antigens, generation of improved adjuvants, use of alternative immunization routes, improving vaccine safety, and finding and establishing the correlates of protection. The second part of the book focuses
Bacterial protein toxins : Fourth European Workshop, Urbino, July 3-July 6, 1989 by European Workshop on Bacterial Protein Toxins( Book )

10 editions published in 1990 in 3 languages and held by 85 WorldCat member libraries worldwide

Vaccines : a health insurance of the 21st Century by Rino Rappuoli( Visual )

8 editions published between 2008 and 2011 in English and held by 66 WorldCat member libraries worldwide

(CIT): John R. LaMontagne Memorial Lecture Poster Rino Rappuoli, Ph. D., currently serves as Global Head Vaccines Research for Novartis Vaccines & Diagnostics (Siena, Italy), a position he has held since 2006. Dr. Rappuoli's research career has focused primarily on disease-causing bacteria, including the microbes that cause diphtheria, pertussis, cholera, and meningococcal meningitis. He has improved the scientific understanding of the molecular mechanisms by which these pathogens cause disease and applied this knowledge to the rational design of innovative tools to prevent infection and disease. After receiving his Ph. D. from the University of Siena, Dr. Rappuoli conducted postgraduate research at Rockefeller University and at Harvard Medical School. In the mid-1980s, while at the Sclavo Research Center in Siena, Dr. Rappuoli began heading a research project on Bordetella pertussis that led to the first recombinant bacterial vaccine against whooping cough. The mutant form of pertussis toxin used in the whooping cough vaccine was the first protein constructed by rational drug design to be approved for use in humans. His work at Sclavo also led to the development of a licensed conjugate vaccine against meningococcus C. Currently, Dr. Rappuoli is developing a vaccine against group B meningococcus using a genome-based approach termed reverse vaccinology. He also is leading research to develop new and improved influenza vaccines, including cell culture-based influenza vaccines and pandemic H5N1 influenza vaccines formulated with the novel MF59 adjuvant. Dr. Rappuoli is co-founder of the field of cellular microbiology, a discipline that merges cell biology and microbiology. The scientific community adopted this new discipline after he and his colleagues published a review paper titled "Cellular Microbiology Emerging" in the journal Science in 1996. Dr. Rappuoli has received numerous awards and honors throughout his career. He was elected to the U.S. National Academy of Sciences 2005, and also is an elected member of the European Molecular Biology Organization (EMBO). In 2005 he also was awarded the Gold Medal by the President of the Italian Republic for his contributions to public healthcare
A Global Perspective on Vaccines: Priorities, Challenges and Online Information by Luciana Leite( )

1 edition published in 2020 in English and held by 34 WorldCat member libraries worldwide

Vaccines have been one of the most important medical discoveries of the last three centuries. Thanks to their development, millions of deaths have been avoided. Together with improved hygiene and antibiotics, vaccines have significantly contributed to the prolongation of life expectancy in high-income countries to a current average of 85 years, compared to 47 years in 1900. However, the continued success of vaccination has recently been hampered due to changes in the perception of vaccines within society. Therefore, there is a critical need to better understand (i) what has been achieved by vaccination thus far and (ii) what is important to further develop vaccines in a world where increased population, aging, travel, urbanization and climate change favor the emergence, evolution and spread of old and new pathogens. In this Research Topic, we gather articles that discuss numerous questions and problems associated with vaccines. The future of vaccine development needs to take in account changing perspectives within our society and that the acceptance of preventative medicine may also change in the years to come
Reverse Vaccinology by Pedro A Reche( )

1 edition published in 2020 in English and held by 34 WorldCat member libraries worldwide

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
Advanced Immunization Technologies for Next Generation Vaccines by Donata Medaglini( )

1 edition published in 2020 in English and held by 34 WorldCat member libraries worldwide

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
Ranking vaccines : a prioritization software tool. Phase II, Prototype of a decision-support system by Institute of Medicine (U.S.)( Book )

3 editions published in 2013 in English and held by 33 WorldCat member libraries worldwide

Annotation
Novel immunologic adjuvants( )

1 edition published in 2011 in English and held by 31 WorldCat member libraries worldwide

The study of adjuvants - substances added to vaccine formulations to increase efficacy -is one of the fastest growing disciplines in immunology and vaccine development. This book reviews the state-of-the-art of development of novel adjuvants and the science that supports them. There is an increasing need of novel adjuvants for preventive vaccines targeting infectious diseases for which conventional formulations have failed. New adjuvants are also needed to improve existing vaccines in the elderly, infants and chronically infected individuals that mount a suboptimal immune response. In addition
New Generation Vaccines, Fourth Edition by Myrone M Levine( )

2 editions published between 2009 and 2016 in English and held by 17 WorldCat member libraries worldwide

Highlighting the latest activities and initiatives of prominent organizations working in the vaccine industry such as the Bill and Melinda Gates Foundation, The Global Alliance for Vaccines and Immunization, WHO, UNICEF, the World Bank, New Generation Vaccines, Fourth Edition, details steps developing countries have taken toward research, development, manufacture, and regulation of several new vaccines for widespread use. This text will:cover the current state-of-the-art techniques in vaccine development - including the successes and the failurestrace vaccine development from the bench to publi
 
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Influenza vaccines for the future
Covers
Guidebook to protein toxins and their use in cell biologyRanking vaccines : applications of a prioritization software toolAdvanced vaccine research : methods for the decade of vaccinesReplicating vaccines : a new generationAntibodies for infectious diseasesProtein and sugar export and assembly in gram-positive bacteriaStaphylococcus aureus : microbiology, pathology, immunology, therapy, and prophylaxisThree dimensional human organotypic models for biomedical research
Alternative Names
Rappuoli, R.

Rappuoli, R. (Rino)

Rappuoli, Rino

Rino Rappuoli American medical researcher

Rino Rappuoli inmunólogu italianu

Rino Rappuoli Italiaans immunoloog

Rino Rappuoli italienischer Mediziner

Rino Rappuoli microbiologo italiano

Раппуоли, Рино итальянский учёный

Ріно Раппуолі

റിനോ റാപ്പൗലി ഇറ്റാലിയൻ മെഡിക്കൽ ഗവേഷകൻ

Languages
English (170)

German (4)