WorldCat Identities

Clapham, David E.

Overview
Works: 18 works in 43 publications in 1 language and 592 library holdings
Genres: Conference papers and proceedings  Periodicals 
Roles: Editor, Author, Other
Publication Timeline
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Most widely held works by David E Clapham
Organellar ion channels and transporters : Society of General Physiologists, 49th Annual Symposium, Marine Biological Laboratory, Woods Hole, Massachusetts, 7-9 September 1995 by Society of General Physiologists( Book )

19 editions published in 1996 in English and held by 528 WorldCat member libraries worldwide

Organellar ion channels and transporters : Marine Biological Laboratory, Woods Hole, Massachusetts, 7-9 September 1995( Book )

1 edition published in 1996 in English and held by 14 WorldCat member libraries worldwide

Annual review of physiology( Book )

4 editions published between 2009 and 2010 in English and held by 11 WorldCat member libraries worldwide

Annual review of physiology( Book )

3 editions published in 2008 in English and held by 10 WorldCat member libraries worldwide

Annual review of physiology( Book )

2 editions published in 2007 in English and held by 10 WorldCat member libraries worldwide

Organellar ion channels and transporters : 7-9 September 1995 [at the Marine Biological Laboratory in Woods Hole, Massachusetts]( Book )

2 editions published in 1996 in English and held by 9 WorldCat member libraries worldwide

A whole tissue model of heart cell aggregates: electrical coupling between cells, membrane impedance, and the extracellular space by David E Clapham( )

1 edition published in 1979 in English and held by 3 WorldCat member libraries worldwide

Ion channels in mammalian primary cilia( Visual )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

(CIT): NIH Neuroscience Series Seminar The Clapham laboratory moved to the Janelia Research Campus in July 2017 and continued working on the ion channels and calcium signals. They have two major interests at present. First, they are interested in the ion channels in primary cilia and how they affect signaling pathways, such as Hedgehog, in embryonic and mature neurons and glia of the hippocampus. They are also pursuing the cryoEM structures of the two main channels of primary cilia so that they can understand their gating. Second, Clapham lab is interested in understanding the two unusual ion channels, TRPM7 and TRPM6. These channels are in all cells, and when genetically deleted, are lethal. The channels are unique in that they possess active kinase domains that when cleaved, enter the nucleus and phosphorylate distinct residues on histones that control chromatin accessibility and thus transcription. Answering these questions will require electrophysiology, advanced light microscopy, mouse genetics, and structural approaches
Remembering Eva Neer : obituary by David E Clapham( )

in English and held by 1 WorldCat member library worldwide

Annual reviev of physiology vol-69,2007 by David Julius( Book )

1 edition published in 2007 in English and held by 1 WorldCat member library worldwide

Annual review of physiology( Book )

1 edition published in 2010 in English and held by 1 WorldCat member library worldwide

Roles of G protein subunits in transmembrane signalling by Eva J Neer( Book )

1 edition published in 1988 in English and held by 1 WorldCat member library worldwide

A whole tissue model of heart cell aggregates electr. coupling between cells, membrane impedance, and the extracellular space by David E Clapham( Book )

1 edition published in 1979 in English and held by 1 WorldCat member library worldwide

TRP ion channels in the nervous system by David E Clapham( Visual )

1 edition published in 2004 in English and held by 1 WorldCat member library worldwide

(CIT): Neurotransmitters, hormones, and pharmacologic agents act by binding specific receptors on the cell surface. Dr. Clapham's lab is interested in how a receptor initiates intracellular events such as the opening of ion channels, the activation of enzymes, or the release of intracellular calcium; and the structures, functions, and relations of receptors, G proteins, ion channels, and calcium. The transient receptor potential (TRP) superfamily comprises a group of non-selective cation channels that sense and respond to changes in their local environments. TRP channels are found in many eukaryotes, from yeast to mammals. They are a diverse group of proteins organized into six families. In the peripheral nervous system, stimuli including temperature, pressure, inflammatory agents, and receptor activation effect TRP-mediated responses
TRP channels as cellular sensors by David E Clapham( )

1 edition published in 2003 in English and held by 0 WorldCat member libraries worldwide

Some like it hot : spicing up ion channels by David E Clapham( )

1 edition published in 1997 in English and held by 0 WorldCat member libraries worldwide

TRP-plik a bifunctional protein with kinase and ion channel activities by Loren W Runnels( )

1 edition published in 2001 in English and held by 0 WorldCat member libraries worldwide

Signal transduction : hot and cold TRP ion channels by David E Clapham( )

1 edition published in 2002 in English and held by 0 WorldCat member libraries worldwide

 
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Annual review of physiology
Covers
Annual review of physiology
Languages
English (43)