Inter-Organization Programme for the Sound Management of Chemicals
Overview
| Works: | 335 works in 969 publications in 2 languages and 24,931 library holdings |
|---|---|
| Genres: | Classification Handbooks and manuals |
| Roles: | Editor, Other |
Publication Timeline
.
Most widely held works by
Inter-Organization Programme for the Sound Management of Chemicals
Dermal absorption by
J Kielhorn(
)
10 editions published in 2006 in English and held by 566 WorldCat member libraries worldwide
Introduction and definitions -- Skin structure and function -- Skin transport mechanisms and theoretical concepts -- Metabolism in the skin -- In vitro tests for dermal absorption -- In vivo tests for dermal absorption -- Comparative studies -- Data collections -- Estimation/prediction of dermal penetration -- Use of dermal penetration studies in risk assessment -- Controversial topics in the assessment of dermal absorption -- Conclusions and recommendations
10 editions published in 2006 in English and held by 566 WorldCat member libraries worldwide
Introduction and definitions -- Skin structure and function -- Skin transport mechanisms and theoretical concepts -- Metabolism in the skin -- In vitro tests for dermal absorption -- In vivo tests for dermal absorption -- Comparative studies -- Data collections -- Estimation/prediction of dermal penetration -- Use of dermal penetration studies in risk assessment -- Controversial topics in the assessment of dermal absorption -- Conclusions and recommendations
2-butenal by
J Kielhorn(
)
11 editions published in 2008 in English and held by 523 WorldCat member libraries worldwide
2-Butenal (also known as crotonaldehyde) is an ab-unsaturated aldehyde and consequently a very reactive compound. It is a chemical intermediate used chiefly in the manufacture of sorbates, solvents, and, to a lesser extent, pharmaceutical products and aroma chemicals. This publication studies the pharmacokinetics, environmental exposure, chemical toxicology and carcinogenicity of 2-butenal. However, to enable an understanding and evaluation of this aldehyde in the context of environmental health, other aldehydes, such as formaldehyde, acetaldehyde, and acrolein, are mentioned for comparison.--Publisher's description
11 editions published in 2008 in English and held by 523 WorldCat member libraries worldwide
2-Butenal (also known as crotonaldehyde) is an ab-unsaturated aldehyde and consequently a very reactive compound. It is a chemical intermediate used chiefly in the manufacture of sorbates, solvents, and, to a lesser extent, pharmaceutical products and aroma chemicals. This publication studies the pharmacokinetics, environmental exposure, chemical toxicology and carcinogenicity of 2-butenal. However, to enable an understanding and evaluation of this aldehyde in the context of environmental health, other aldehydes, such as formaldehyde, acetaldehyde, and acrolein, are mentioned for comparison.--Publisher's description
The WHO recommended classification of pesticides by hazard and guidelines to classification 2009 by
International Program on Chemical Safety(
)
10 editions published in 2010 in English and held by 518 WorldCat member libraries worldwide
"The WHO Recommended Classification of Pesticides by Hazard was approved by the 28th World Health Assembly in 1975 and has since gained wide acceptance. When it was published in the WHO Chronicle, 29, 397-401 (1975), an annex, which was not part of the Classification, illustrated its use by listing examples of classification of some pesticidal active ingredients and their formulations. Later suggestions were made by Member States and pesticide registration authorities that further guidance should be given on the classification of individual pesticides. Guidelines were first issued in 1978, and have since been revised and reissued every few years. Up until the present revision the original guidelines approved by the World Health Assembly in 1975 have been followed without amendment. In December, 2002 the United Nations Committee of Experts on the Transport of Dangerous Goods and on the Globally Harmonized System of Classification and Labelling of Chemicals (UNCETDG/GHS) approved a document called 'The Globally Harmonized System of Classification and Labelling of Chemicals' with the intent to provide a globally-harmonized system¹ (GHS) to address classification of chemicals, labels, and safety data sheets. The GHS (with subsequent revisions) is now being widely used for the classification and labeling of chemicals worldwide. For this revision of the Classification the WHO Hazard Classes have been aligned in an appropriate way with the GHS Acute Toxicity Hazard Categories for acute oral or dermal toxicity as the starting point for allocating pesticides to a WHO Hazard Class (with adjustments for individual pesticides where required). It is anticipated that few of the more toxic pesticides will change WHO Hazard Class as a result of this change. As has always been the case, the classification of some pesticides has been adjusted to take account of severe hazards to health other than acute toxicity (as described in Part II). The GHS Acute Toxicity Hazard Category for each pesticide is now presented alongside the existing information"--Page 1
10 editions published in 2010 in English and held by 518 WorldCat member libraries worldwide
"The WHO Recommended Classification of Pesticides by Hazard was approved by the 28th World Health Assembly in 1975 and has since gained wide acceptance. When it was published in the WHO Chronicle, 29, 397-401 (1975), an annex, which was not part of the Classification, illustrated its use by listing examples of classification of some pesticidal active ingredients and their formulations. Later suggestions were made by Member States and pesticide registration authorities that further guidance should be given on the classification of individual pesticides. Guidelines were first issued in 1978, and have since been revised and reissued every few years. Up until the present revision the original guidelines approved by the World Health Assembly in 1975 have been followed without amendment. In December, 2002 the United Nations Committee of Experts on the Transport of Dangerous Goods and on the Globally Harmonized System of Classification and Labelling of Chemicals (UNCETDG/GHS) approved a document called 'The Globally Harmonized System of Classification and Labelling of Chemicals' with the intent to provide a globally-harmonized system¹ (GHS) to address classification of chemicals, labels, and safety data sheets. The GHS (with subsequent revisions) is now being widely used for the classification and labeling of chemicals worldwide. For this revision of the Classification the WHO Hazard Classes have been aligned in an appropriate way with the GHS Acute Toxicity Hazard Categories for acute oral or dermal toxicity as the starting point for allocating pesticides to a WHO Hazard Class (with adjustments for individual pesticides where required). It is anticipated that few of the more toxic pesticides will change WHO Hazard Class as a result of this change. As has always been the case, the classification of some pesticides has been adjusted to take account of severe hazards to health other than acute toxicity (as described in Part II). The GHS Acute Toxicity Hazard Category for each pesticide is now presented alongside the existing information"--Page 1
Dermal exposure by
International Program on Chemical Safety(
)
6 editions published in 2014 in English and held by 437 WorldCat member libraries worldwide
"This Environmental Health Criteria (EHC) series publication addresses dermal exposure to chemicals. It describes sources and pathways of dermal exposure, models and tools to estimate dermal exposure and methods for dermal exposure prevention and reduction Furthermore, the EHC introduces skin diseases associated with dermal exposure. This EHC aims to provide information to national regulatory authorities to assist in conducting health risk assessments and managing the risk involving dermal exposure to chemicals."--Publisher's description
6 editions published in 2014 in English and held by 437 WorldCat member libraries worldwide
"This Environmental Health Criteria (EHC) series publication addresses dermal exposure to chemicals. It describes sources and pathways of dermal exposure, models and tools to estimate dermal exposure and methods for dermal exposure prevention and reduction Furthermore, the EHC introduces skin diseases associated with dermal exposure. This EHC aims to provide information to national regulatory authorities to assist in conducting health risk assessments and managing the risk involving dermal exposure to chemicals."--Publisher's description
Principles and methods for the assessment of risk from essential trace elements by
Inter-Organization Programme for the Sound Management of Chemicals(
Book
)
6 editions published between 2001 and 2002 in English and held by 290 WorldCat member libraries worldwide
Annotation
6 editions published between 2001 and 2002 in English and held by 290 WorldCat member libraries worldwide
Annotation
Vinyl chloride by
International Program on Chemical Safety(
Book
)
6 editions published in 1999 in English and held by 270 WorldCat member libraries worldwide
6 editions published in 1999 in English and held by 270 WorldCat member libraries worldwide
Principles of characterizing and applying human exposure models by
International Program on Chemical Safety(
Book
)
6 editions published in 2005 in English and held by 251 WorldCat member libraries worldwide
The objective of this manual is to provide guidance to risk assessors on the use of quantitative toxicokinetic and toxicodynamic data to address interspecies and interindividual differences in dose and concentration-response assessment. Section 1 focuses on the relevance of this guidance in the context of the broader risk assessment paradigm and other initiatives of the International Program on Chemical Safety (IPCS) project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals. Technical background material is presented in section 2, followed by generic guidance for the development of chemical-specific adjustment factors in section 3 and accompanying summary figures. Illustrative case-studies are included in an Appendix, and a glossary of terms is also provided.--Publisher's description
6 editions published in 2005 in English and held by 251 WorldCat member libraries worldwide
The objective of this manual is to provide guidance to risk assessors on the use of quantitative toxicokinetic and toxicodynamic data to address interspecies and interindividual differences in dose and concentration-response assessment. Section 1 focuses on the relevance of this guidance in the context of the broader risk assessment paradigm and other initiatives of the International Program on Chemical Safety (IPCS) project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals. Technical background material is presented in section 2, followed by generic guidance for the development of chemical-specific adjustment factors in section 3 and accompanying summary figures. Illustrative case-studies are included in an Appendix, and a glossary of terms is also provided.--Publisher's description
OECD guiding principles for chemical accident prevention, preparedness and response : guidance for industry (including management
and labour), public authorities, communities and other stakeholders by
Organisation for Economic Co-operation and Development(
Book
)
8 editions published in 2003 in English and held by 225 WorldCat member libraries worldwide
This second comprehensive edition of these Principles is to help public authorities, industry and communities worldwide anticipate accidents involving hazardous substances resulting from technological and natural disasters, as well as sabotage. It addresses the following issues: preventing the occurrence of chemical accidents and near-misses; preparing for accidents through emergency planning, public communication, etc.; responding to accidents and minimising their adverse effects; and following-up to accidents, regarding clean-up, reporting and investigation
8 editions published in 2003 in English and held by 225 WorldCat member libraries worldwide
This second comprehensive edition of these Principles is to help public authorities, industry and communities worldwide anticipate accidents involving hazardous substances resulting from technological and natural disasters, as well as sabotage. It addresses the following issues: preventing the occurrence of chemical accidents and near-misses; preparing for accidents through emergency planning, public communication, etc.; responding to accidents and minimising their adverse effects; and following-up to accidents, regarding clean-up, reporting and investigation
Guidance on safety performance indicators : guidance for industry, public authorities and communities for developing SPI programmes
related to chemical accident prevention, preparedness and response by
Organisation for Economic Co-operation and Development(
Book
)
9 editions published in 2003 in English and French and held by 222 WorldCat member libraries worldwide
9 editions published in 2003 in English and French and held by 222 WorldCat member libraries worldwide
Principles for modelling dose-response for the risk assessment of chemicals by
WHO Task Group on Environmental Health Criteria on Principles for Modelling Dose-Response for the Risk Assessment of Chemicals(
Book
)
9 editions published in 2009 in English and held by 212 WorldCat member libraries worldwide
This volume is part of the ongoing review of the underlying scientific bases for decision-making in chemical risk assessment by International Program on Chemical Safety. It involves specific consideration of the area of dose-response assessment in the evaluation of information from toxicological studies in animals and from human clinical and epidemiological studies. It covers toxicants with threshold effects and those for which there may be no practical threshold, such as substances that are genotoxic and carcinogenic. The discussions are concerned with that subset of cause-effect relationships commonly referred to as dose-response models, which are typically used to characterize the biological effects of intentional (e.g. drugs and nutrients) and unintentional (e.g. contaminants) exposure to chemicals. This report is intended primarily to provide descriptive guidance for risk assessors in using dose-response modeling in hazard characterization. It will also provide mathematical modelers with an appreciation of issues to be considered when modeling in the context of the risk assessment process. Risk managers will be able to obtain a general understanding of the applications and limitations of dose-response modeling. For both risk assessors and risk managers, some considerations for communicating the results of risk assessments that use dose-response modeling are presented.--Publisher's description
9 editions published in 2009 in English and held by 212 WorldCat member libraries worldwide
This volume is part of the ongoing review of the underlying scientific bases for decision-making in chemical risk assessment by International Program on Chemical Safety. It involves specific consideration of the area of dose-response assessment in the evaluation of information from toxicological studies in animals and from human clinical and epidemiological studies. It covers toxicants with threshold effects and those for which there may be no practical threshold, such as substances that are genotoxic and carcinogenic. The discussions are concerned with that subset of cause-effect relationships commonly referred to as dose-response models, which are typically used to characterize the biological effects of intentional (e.g. drugs and nutrients) and unintentional (e.g. contaminants) exposure to chemicals. This report is intended primarily to provide descriptive guidance for risk assessors in using dose-response modeling in hazard characterization. It will also provide mathematical modelers with an appreciation of issues to be considered when modeling in the context of the risk assessment process. Risk managers will be able to obtain a general understanding of the applications and limitations of dose-response modeling. For both risk assessors and risk managers, some considerations for communicating the results of risk assessments that use dose-response modeling are presented.--Publisher's description
Resorcinol by
S. K Hahn(
Book
)
13 editions published in 2006 in English and held by 204 WorldCat member libraries worldwide
Resorcinol is a white crystalline compound used largely in the rubber industry and in wood bonding applications and is an important source of chemical intermediate in the manufacture of speciality chemicals. Other uses of the chemical include the manufacture of dyestuffs, pharmaceuticals, flame retardants, agricultural chemicals, fungicidal creams and lotions, and hair dye formulations. This Concise International Assessment Document (CICAD) evaluates the scientific literature on the health and environmental effects of resorcinol based on selected national and regional evaluations. Uncertainties in the risk assessment are set out for both human health and the environment--Publisher's description
13 editions published in 2006 in English and held by 204 WorldCat member libraries worldwide
Resorcinol is a white crystalline compound used largely in the rubber industry and in wood bonding applications and is an important source of chemical intermediate in the manufacture of speciality chemicals. Other uses of the chemical include the manufacture of dyestuffs, pharmaceuticals, flame retardants, agricultural chemicals, fungicidal creams and lotions, and hair dye formulations. This Concise International Assessment Document (CICAD) evaluates the scientific literature on the health and environmental effects of resorcinol based on selected national and regional evaluations. Uncertainties in the risk assessment are set out for both human health and the environment--Publisher's description
Human exposure assessment by
D. L MacIntosh(
Book
)
7 editions published in 2000 in English and held by 199 WorldCat member libraries worldwide
A guide to the concepts, procedures, statistical methods and models used to assess human exposure to environmental chemicals. It offers advice on the design and conduct of studies, the interpretation of findings, and the best methods for ensuring the reliability and reproducibility of results
7 editions published in 2000 in English and held by 199 WorldCat member libraries worldwide
A guide to the concepts, procedures, statistical methods and models used to assess human exposure to environmental chemicals. It offers advice on the design and conduct of studies, the interpretation of findings, and the best methods for ensuring the reliability and reproducibility of results
Skin sensitization in chemical risk assessment by
International Program on Chemical Safety(
Book
)
6 editions published between 2007 and 2008 in English and held by 198 WorldCat member libraries worldwide
This publication presents the conclusions of an IPCS Workshop on Skin Sensitization in Chemical Risk Assessment. The workshop focused on the question of methods for dose-response assessment, to evaluate the relative ability of a chemical to induce sensitization in the skin, and hence inform risk assessment for humans. In addition this publication includes a series of short articles on this topic by leading experts in the field. The conclusions of the workshop cover such aspects as the nature and utility for risk assessment of the data produced by non-animal test methods (such as quantitative structure-activity relationships), in vitro testing approaches, animal test methods, and epidemiological studies. While traditional animal test methods used for identification and regulation of skin sensitizers have focused on determining whether or not a substance is a sensitizer, this report describes the use of tests for deriving more informative potency information.--Publisher's description
6 editions published between 2007 and 2008 in English and held by 198 WorldCat member libraries worldwide
This publication presents the conclusions of an IPCS Workshop on Skin Sensitization in Chemical Risk Assessment. The workshop focused on the question of methods for dose-response assessment, to evaluate the relative ability of a chemical to induce sensitization in the skin, and hence inform risk assessment for humans. In addition this publication includes a series of short articles on this topic by leading experts in the field. The conclusions of the workshop cover such aspects as the nature and utility for risk assessment of the data produced by non-animal test methods (such as quantitative structure-activity relationships), in vitro testing approaches, animal test methods, and epidemiological studies. While traditional animal test methods used for identification and regulation of skin sensitizers have focused on determining whether or not a substance is a sensitizer, this report describes the use of tests for deriving more informative potency information.--Publisher's description
Disinfectants and disinfectant by-products by
John D Spengler(
Book
)
7 editions published in 2000 in English and held by 197 WorldCat member libraries worldwide
This book evaluates the risks to human health posed by disinfectants and disinfectant by-products found in treated drinking-water. Noting that chlorine and other widely-used disinfectants were approved for use almost 100 years ago when toxicological data were limited the report responds to the need for reassurance that consumption of treated drinking-water will not have adverse effects on health. Particular concern centres on the potential of chlorine to react with natural organic matter and form a large number of by-products some of which have been intensively studied as potential human carci
7 editions published in 2000 in English and held by 197 WorldCat member libraries worldwide
This book evaluates the risks to human health posed by disinfectants and disinfectant by-products found in treated drinking-water. Noting that chlorine and other widely-used disinfectants were approved for use almost 100 years ago when toxicological data were limited the report responds to the need for reassurance that consumption of treated drinking-water will not have adverse effects on health. Particular concern centres on the potential of chlorine to react with natural organic matter and form a large number of by-products some of which have been intensively studied as potential human carci
Principles for the assessment of risks to human health from exposure to chemicals by
International Program on Chemical Safety(
Book
)
2 editions published in 1999 in English and held by 192 WorldCat member libraries worldwide
2 editions published in 1999 in English and held by 192 WorldCat member libraries worldwide
Health effects of interactions between tobacco use and exposure to other agents by
K Rothwell(
Book
)
5 editions published in 1999 in English and held by 191 WorldCat member libraries worldwide
5 editions published in 1999 in English and held by 191 WorldCat member libraries worldwide
Copper by
International Program on Chemical Safety(
Book
)
6 editions published in 1998 in English and held by 190 WorldCat member libraries worldwide
6 editions published in 1998 in English and held by 190 WorldCat member libraries worldwide
Flame retardants : tris(2-butoxyethyl) phosphate, tris(2-ethylhexyl) phosphate and tetrakis(hydroxymethyl) phosphonium salts by
G. J. van Esch(
Book
)
6 editions published in 2000 in English and held by 190 WorldCat member libraries worldwide
Evaluates the risks to human health and the environment posed by exposure to selected flame retardants including chemicals widely used to treat textiles. Although data were inadequate to support a full scientific evaluation the report reaches several preliminary conclusions concerning the likelihood of risks to human health. Compounds are covered in separate monographs. Tris(2-butoxyethyl) phosphate (TBEP) is covered in the first. TBEP is used in floor polishes and as a plasticizer in rubber and plastics. Studies of concentrations in various environmental samples show that TBEP is readily biod
6 editions published in 2000 in English and held by 190 WorldCat member libraries worldwide
Evaluates the risks to human health and the environment posed by exposure to selected flame retardants including chemicals widely used to treat textiles. Although data were inadequate to support a full scientific evaluation the report reaches several preliminary conclusions concerning the likelihood of risks to human health. Compounds are covered in separate monographs. Tris(2-butoxyethyl) phosphate (TBEP) is covered in the first. TBEP is used in floor polishes and as a plasticizer in rubber and plastics. Studies of concentrations in various environmental samples show that TBEP is readily biod
Selected non-heterocyclic polycyclic aromatic hydrocarbons by
International Program on Chemical Safety(
Book
)
6 editions published in 1998 in English and held by 190 WorldCat member libraries worldwide
6 editions published in 1998 in English and held by 190 WorldCat member libraries worldwide
Methyl tertiary-butyl ether by
M Gillner(
Book
)
8 editions published in 1998 in English and held by 188 WorldCat member libraries worldwide
Enth. eine franz. und span. Zusammenfassung
8 editions published in 1998 in English and held by 188 WorldCat member libraries worldwide
Enth. eine franz. und span. Zusammenfassung
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Related Identities
- World Health Organization Other Publisher Editor
- International Program on Chemical Safety Other Editor
- United Nations Environment Programme Other Editor
- International Labour Organisation Editor
- Kielhorn, J. Author Editor
- Dobson, S. (Stuart) Author Editor
- Meek, M. E. Author Editor
- OECD iLibrary
- Mangelsdorf, I. Editor
- Organisation for Economic Co-operation and Development Publisher Editor
Associated Subjects
Butyl methyl ether--Environmental aspects Butyl methyl ether--Toxicology Chemicals--Accidents Chemicals--Physiological effect Chemicals--Safety measures Copper--Environmental aspects Copper--Toxicology Crotonaldehyde--Environmental aspects Crotonaldehyde--Toxicology Dermatotoxicology Disinfection and disinfectants--Environmental aspects Disinfection and disinfectants--Toxicology Drugs--Dose-response relationship Emergency management Environmental health Environmental risk assessment--Mathematical models Environmental toxicology Hazardous substances--Accidents Hazardous substances--Risk assessment Hazardous substances--Safety measures Health risk assessment Health risk assessment--Mathematical models Organophosphorus compounds--Toxicology Pesticides Pesticides--Toxicology Pharmacokinetics Polycyclic aromatic hydrocarbons--Environmental aspects Polycyclic aromatic hydrocarbons--Physiological effect Polycyclic aromatic hydrocarbons--Toxicology Resorcinol--Environmental aspects Resorcinol--Toxicology Risk assessment Sanitation--Health aspects Sanitation--International cooperation Skin--Physiology Skin tests Tobacco--Physiological effect Tobacco smoke pollution Tobacco--Toxicology Toxicity testing Toxicology Trace elements Trace elements--Health aspects Trace elements in nutrition Trace elements--Physiological effect Trace elements--Toxicology Vinyl chloride Vinyl chloride--Toxicology Water--Purification--Environmental aspects Water--Purification--Health aspects
Covers
Alternative Names
FAO Inter-Organization Programme for the Sound Management of Chemicals
I.O.M.C.
I.O.M.C. (Inter-Organization Programme for the Sound Management of Chemicals)
International Labour Organisation Inter-Organization Programme for the Sound Management of Chemicals
IOMC
IOMC (Inter-Organization Programme for the Sound Management of Chemicals)
OECD Inter-Organization Programme for the Sound Management of Chemicals
UNEP Inter-Organization Programme for the Sound Management of Chemicals
UNIDO Inter-Organization Programme for the Sound Management of Chemicals
Weltgesundheitsorganisation Inter-Organization Programme for the Sound Management of Chemicals
Languages