WorldCat Identities

Hirschfield, Gideon M.

Overview
Works: 26 works in 61 publications in 2 languages and 845 library holdings
Genres: Examinations  Academic theses  Conference papers and proceedings 
Roles: Editor, Author, Contributor, Other, htt
Publication Timeline
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Most widely held works by Gideon M Hirschfield
Autoimmune hepatitis : a guide for practicing clinicians by Gideon M Hirschfield( )

17 editions published between 2010 and 2012 in English and held by 371 WorldCat member libraries worldwide

Annotation
Biliary disease : from science to clinic( )

13 editions published between 2017 and 2018 in English and German and held by 217 WorldCat member libraries worldwide

This book addresses the current understanding of the diagnosis and management of biliary disease across all ages, with emphasis on how the latest advances in clinical science may be integrated into current and future therapies. The coverage is wide ranging, encompassing congenital and acquired conditions including cholestatic syndromes, biliary atresia, drug-induced cholestasis, primary biliary cholangitis/cirrhosis, primary sclerosing cholangitis, cholangiocarcinoma, gallstone disease, and autoimmune sclerosing cholangitis. With contributions from basic and clinical scientists, the relevance of state-of-the-art mechanistic biology to diagnosis, treatment, and future opportunities for drug design is clearly explained. The balance between science and clinical practice will ensure that this book makes a lasting contribution to the field. A broad readership will find the book easy to access and a rich source of information on current best practice and evolving management strategies
Autoimmune liver disease : management and clinical practice by James Neuberger( )

6 editions published in 2020 in English and held by 211 WorldCat member libraries worldwide

"Autoimmune Liver Disease discusses the current understanding about autoimmune liver diseases, focusing on pathogenesis, diagnosis and management. The first section covers the current immunological thinking about autoimmunity and focus on liver diseases with emphasis on the spectrum, significance, use and abuse of autoantibodies and on the implications of the recent advances in the genetics of autoimmunity to allow the reader to place these exciting developments in context. The second section describes four main hepatic autoimmune liver diseases and follows a common format that focuses on aspects of diagnosis and management. Liver transplantation plays an important role in treatment so timing and outcomes are covered: recurrence of autoimmune liver disease is important not only for the recipient and their clinicians but also sheds light on the pathogenesis. De novo autoimmune hepatitis is included in both clinical and scientific chapters. Finally, the authors treat three areas where experience has shown there is uncertainty. The final chapter includes reference to optimal approaches to patient management, including patient empowerment. To ensure that the whole clinical spectrum of autoimmune liver disease is covered, each chapter is jointly covered by contributing authors who are clinicians caring for adult, transitional and paediatric patients"--
Clinical hepatology practice in 2016 : from science to therapy : Symposium 204, Official Congress Report, Birmingham, September 2016( )

1 edition published in 2017 in English and held by 11 WorldCat member libraries worldwide

IgG4 Related disease - a retrospective descriptive study highlighting Canadian experiences in diagnosis and management by Harshna Patel( )

1 edition published in 2013 in English and held by 2 WorldCat member libraries worldwide

C-reactive protein and enhancement of tissue damage : a potential therapeutic target by Gideon M Hirschfield( Book )

2 editions published in 2006 in English and held by 2 WorldCat member libraries worldwide

Clinical Hepatology Practice in 2016: from Science to Therapy Symposium 204, official congress report Birmingham September 2-3, 2016 by Clinical Hepatology Practice in 2016: from Science to Therapy( Book )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

BAT117213: Ileal bile acid transporter (IBAT) inhibition as a treatment for pruritus in primary biliary cirrhosis: study protocol for a randomised controlled trial by Vinod S Hegade( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Factors that Influence Health-Related Quality of Life in Patients with Primary Sclerosing Cholangitis by Angela C Cheung( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

OX40, OX40L and Autoimmunity: a Comprehensive Review by Gwilym J Webb( )

1 edition published in 2015 in English and held by 2 WorldCat member libraries worldwide

Multiparametric magnetic resonance imaging for quantitation of liver disease: a two-centre cross-sectional observational study by Natasha McDonald( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Primary Biliary Cirrhosis( )

1 edition published in 2011 in English and held by 2 WorldCat member libraries worldwide

Medical masterclass : gastroenterology and hepatology by John D Firth( Book )

2 editions published in 2018 in Undetermined and English and held by 2 WorldCat member libraries worldwide

In this eighth book of the Medical Masterclass series, Gastroenterology and hepatology, we cover all the common clinical presentations. Topics include taking a patient history; physical signs that patients may have; planning a strategy for investigation and treatment; and discussing difficult issues with patients and their relatives (useful for both clinical practice and PACES exam practise). The key points are emphasised, and this book also includes self-assessment questions (SAQs) in the style of the MRCP(UK) Part 1 and Part 2 exams. This third edition of Medical Masterclass is updated to reflect changes to the MRCP(UK) exam. The Medical Masterclass books have an easy-to-read format, clinical images and highlighted key points throughout. Considered to be the most comprehensive MRCP(UK) revision package available. Produced by the Royal College of Physicians, the Medical Masterclass series is written by over 75 authors and contributors, under the editor- in-chief Dr John Firth DM FRCP
The Pathogenesis of Primary Biliary Cholangitis: A Comprehensive Review( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Changes in natural killer cells and exhausted memory regulatory T Cells with corticosteroid therapy in acute autoimmune hepatitis( )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47, XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Abstract : Objective: More than 80% of autoimmune disease predominantly affects females, but the mechanism for this female bias is poorly understood. We suspected that an X chromosome dose effect accounts for this, and we undertook this study to test our hypothesis that trisomy X (47, XXX; occurring in <" in 1, 000 live female births) would be increased in patients with female-predominant diseases (systemic lupus erythematosus [SLE], primary Sjögren's syndrome [SS], primary biliary cirrhosis, and rheumatoid arthritis [RA]) compared to patients with diseases without female predominance (sarcoidosis) and compared to controls. Methods: All subjects in this study were female. We identified subjects with 47, XXX using aggregate data from single-nucleotide polymorphism arrays, and, when possible, we confirmed the presence of 47, XXX using fluorescence in situ hybridization or quantitative polymerase chain reaction. Results: We found 47, XXX in 7 of 2, 826 SLE patients and in 3 of 1, 033 SS patients, but in only 2 of 7, 074 controls (odds ratio in the SLE and primary SS groups 8.78 [95% confidence interval 1.67-86.79], P = 0.003 and odds ratio 10.29 [95% confidence interval 1.18-123.47], P = 0.02, respectively). One in 404 women with SLE and 1 in 344 women with SS had 47, XXX. There was an excess of 47, XXX among SLE and SS patients. Conclusion: The estimated prevalence of SLE and SS in women with 47, XXX was <".5 and <".9 times higher, respectively, than that in women with 46, XX and <"5 and <"1 times higher, respectively, than that in men with 46, XY. No statistically significant increase of 47, XXX was observed in other female-biased diseases (primary biliary cirrhosis or RA), supporting the idea of multiple pathways to sex bias in autoimmunity
Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Abstract : Objective: Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE) are related by clinical and serologic manifestations as well as genetic risks. Both diseases are more commonly found in women than in men, at a ratio of ~10 to 1. Common X chromosome aneuploidies, 47, XXY and 47, XXX, are enriched among men and women, respectively, in either disease, suggesting a dose effect on the X chromosome. Methods: We examined cohorts of SS and SLE patients by constructing intensity plots of X chromosome single-nucleotide polymorphism alleles, along with determining the karyotype of selected patients. Results: Among ~2, 500 women with SLE, we found 3 patients with a triple mosaic, consisting of 45, X/46, XX/47, XXX. Among ~2, 100 women with SS, 1 patient had 45, X/46, XX/47, XXX, with a triplication of the distal p arm of the X chromosome in the 47, XXX cells. Neither the triple mosaic nor the partial triplication was found among the controls. In another SS cohort, we found a mother/daughter pair with partial triplication of this same region of the X chromosome. The triple mosaic occurs in ~1 in 25, 000-50, 000 live female births, while partial triplications are even rarer. Conclusion: Very rare X chromosome abnormalities are present among patients with either SS or SLE and may inform the location of a gene(s) that mediates an X dose effect, as well as critical cell types in which such an effect is operative
 
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Autoimmune liver disease : management and clinical practice
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Biliary disease : from science to clinicAutoimmune liver disease : management and clinical practice
Alternative Names
Gideon M Hirschfield gastroenteroloog

Hirschfeld, G.

Hirschfield, Gideon.

Hirschfield, Gideon M.

Hirschfield, Gideon Morris

Languages
English (53)

German (1)