Dudley, Joel T.

Exploring personal genomics by Joel T Dudley( )

17 editions published between 2013 and 2014 in English and held by 1,285 WorldCat member libraries worldwide

This book aims to support undergraduate and graduate studies in medicine, genetics, molecular biology, and bioinformatics. Additionally, the design of the content is such that medical practitioners, professionals working in the biomedical sciences or related fields, and motivated lay individuals interested in exploring their personal genetic data should find it relevant and approachable. -- Publisher

Drug repositioning : approaches and applications for neurotherapeutics by Joel T Dudley( )

6 editions published between 2016 and 2019 in English and held by 127 WorldCat member libraries worldwide

3.1.1 Industry and Government Drug Repurposing -- 3.1.2 Not-for-Profit Drug Repurposing -- 3.1.3 Additional Advantages to Generic Drug Repurposing -- 3.1.4 Meeting the Challenges of Drug Repurposing -- 3.2 How Do Ideas for Drug Repurposing Come to NPOs? -- 3.3 Specific Examples of NPOs Engaged in Drug Repurposing -- 3.3.1 GlobalCures -- 3.3.1.1 FIND -- 3.3.1.2 FUND -- 3.3.1.3 SHARE -- 3.3.2 Cures Within Reach -- 3.3.3 AKU Society -- 3.3.4 The Michael J. Fox Foundation -- 3.3.5 TIRCON -- References -- Section II: Repositioning Approaches and Technologies -- Chapter 4: Systematic Drug Repositioning -- 4.1 Introduction -- 4.2 Technological Overview -- 4.2.1 Computational Drug Repositioning -- 4.2.1.1 Literature-Based Methods -- 4.2.1.2 Information Extraction -- 4.2.1.3 Exploiting Ontologies and Other Databases -- 4.2.2 Cheminformatics, In Vitro and Phenotypic Screening -- 4.2.2.1 Cheminformatics -- 4.2.2.2 In Vitro and In Vivo Drug Screening -- 4.3 Drug Repositioning versus Benefit/Risk Assessment: Two Sides of the Same Coin -- 4.4 Case Studies -- 4.4.1 Identifying Risk Factors for the Development of Statin-Induced Diabetes Mellitus -- 4.4.2 Elucidating the Biological Mechanism Underlying an ADR: The Case of Telithromycin -- 4.4.3 From Psoriasis to Multiple Sclerosis: The Case of Dimethyl Fumarate -- 4.4.4 Coping with More than One Patient's Needs at the Same Time: Using Pirlindol, an Antidepressant, for Multiple Sclerosis -- 4.5 Intellectual Properties and Business Considerations -- 4.5.1 Obtaining IP Protection -- 4.5.2 Monetizing a New Use -- 4.5.3 Off-Label Uses -- References -- Chapter 5: Technical Tools for Computational Drug Repositioning -- 5.1 Introduction -- 5.2 Technical Background -- 5.2.1 Machine Learning -- 5.2.2 Supervised Learning -- 5.2.2.1 Support Vector Machines -- 5.2.2.2 The Overfitting Problem

Latent physiological factors of complex human diseases revealed by independent component analysis of clinarrays by David P Chen( )

1 edition published in 2010 in English and held by 2 WorldCat member libraries worldwide

Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia by Benjamin Readhead( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits by Benjamin S Glicksberg( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Deep learning predicts hip fracture using confounding patient and healthcare variables by Marcus A Badgeley( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Computational prediction and experimental validation associating FABP-1 and pancreatic adenocarcinoma with diabetes by Ravi N Sharaf( )

1 edition published in 2011 in English and held by 2 WorldCat member libraries worldwide

Expression-based drug screening of neural progenitor cells from individuals with schizophrenia by Benjamin Readhead( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Pharmacological risk factors associated with hospital readmission rates in a psychiatric cohort identified using prescriptome data mining by Khader Shameer( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

<> by Jean-Vianney Haure-Mirande( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide