WorldCat Identities

Embi, Peter J.

Overview
Works: 13 works in 28 publications in 1 language and 363 library holdings
Genres: Handbooks and manuals  Academic theses 
Roles: Editor, Contributor, Other, Author, htt
Classifications: R858, 610.3
Publication Timeline
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Most widely held works by Peter J Embi
Translational informatics : realizing the promise of knowledge-driven healthcare by Philip R. O Payne( )

15 editions published between 2014 and 2015 in English and held by 330 WorldCat member libraries worldwide

Emergent and multidisciplinary research paradigms have fundamentally transformed biomedical science and the delivery of clinical care. A common theme spanning such transformative changes is the use of rigorous and systematic approaches to the collection, management, integration, analysis, and dissemination of data. Unfortunately, the absence of well-established theoretical and practical frameworks intended to address such needs remains a major impediment to the realization of a translational and knowledge-driven healthcare system. This book provides practical advice on the integrative and translational methodologies and frameworks that have transformed modern biomedical research Translational Informatics presents a broad framework and specific examples of how the deep integration of biomedical informatics with both biomedical research and clinical care delivery is essential to overcoming such barriers and achieving the benefits of a knowledge-based approach to the delivery of high-performance, quality, safe, and individually tailored healthcare. It will be of great value to a wide range of professionals involved in the discipline, as it: Defines the challenges and opportunities surrounding translational medicine, with a focus on the data, information, and knowledge needed to achieve such a healthcare model Introduces readers to core biomedical informatics theories and methods underlying the translational medicine paradigm Discusses future directions for the field of translational medicine
Survival manual : a guide to the clinical years by American Medical Student Association( Book )

2 editions published in 1997 in English and held by 15 WorldCat member libraries worldwide

Targeted cellular ionic calcium chelation by oxalates: Implications for the treatment of tumor cells by Abraham Embi( )

1 edition published in 2012 in English and held by 2 WorldCat member libraries worldwide

Computational challenges and human factors influencing the design and use of clinical research participant eligibility pre-screening tools by Taylor R Pressler( )

1 edition published in 2012 in English and held by 2 WorldCat member libraries worldwide

Rethinking the role and impact of health information technology: informatics as an interventional discipline by Philip R. O Payne( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Community-level determinants of obesity: harnessing the power of electronic health records for retrospective data analysis by Caryn Roth( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

Physicians' perceptions of an electronic health record-based clinical trial alert approach to subject recruitment: A survey by Peter J Embi( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

The Emerging Role of the Chief Research Informatics Officer in Academic Health Centers( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

Usability and Workflow Evaluation of "RhEumAtic Disease activitY" (READY) A Mobile Application for Rheumatology Patients and Providers( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

Perceived impact of computerized physician documentation on education and clinical practice in a teaching hospital : a thesis by Peter J Embi( Book )

1 edition published in 2002 in English and held by 1 WorldCat member library worldwide

In Reply to Severance( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Inter-observer reliability assessments in continuous observation time motion studies by Marcelo A Lopetugui Lazo( )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

Understanding clinical workflow is critical for researchers and decision makers in healthcare. Continuous observation time motion studies (TMS) enhance clinical workflow studies by providing quantitative data required for in-depth analyses. However, methodological inconsistencies have been reported in continuous observation TMS, potentially reducing the validity of TMS' data and limiting their contribution to the general state of knowledge. Among the major concerns, the lack of methods to ensure the reliability of human observers stands as a priority. We aimed to contribute to workflow research by studying current Inter-Observer Reliability Assessment (IORA) methods in continuous observation TMS, particularly workflow time studies. We reviewed the current practices, assessed the suitability and limitations, bringing awareness of the limitations of the single-dimensionality evaluation methods. We proposed and validated a first contribution towards a comprehensive and meaningful IORA methodology: a composite IORA protocol evaluating agreement in multiple dimensions (proportion, naming, duration, sequence and timing), providing useful information for observers' training and a meaningful quantitative IORA report. Applicability in multi-tasking and multi-focus models is the next step in IORA research, finally aiming at a meaningful and valid time motion-driven workflow analysis methodology
A gene co-expression network mining approach for differential expression analysis by Daniel Colin Morgan( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Biomarkers are the actionable factors differentiating any condition states, specifically disease response and non-response to treatment. They have been used as screening measures to indicate surrogate or subclinical manifestations, and are also prime targets of drug repositioning approaches. We aim to identify gene sub-networks involved in response to a drug by implementing a data-mining algorithm that identifies genes with highly correlated expression across the population, concomitantly significantly variable between response and non-response cohorts to allow differentiation. Our greedy Quasi-Clique Merger implementation, localMax-eQCM, is tuned for identifying unique sub-network modules by restricting initial gene pairs to only those of highest local co-expression (a rare event), thereafter keeping with the original QCM, that each and every gene within the sub-network be co-expressed to a high degree (Figure 2.3). We are then able to differentiate differentially expressed modules between response subpopulations by using a t-test among respective eigengene. This method of biomarker evaluation could ultimately be employed to assign patients to receive chemotherapy, predicted to productively respond based upon biomarker screening. We implement our algorithm across CCLE gene expression from a NSCLC large and squamous cell subpopulation, of which cell lines were immortalized and subsequent Taxol response profiles (IC50) measured. We identified three sub-network modules highly correlated to Taxol response in this way
 
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Translational informatics : realizing the promise of knowledge-driven healthcare
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English (28)