WorldCat Identities

Cohen, Saul G.

Overview
Works: 14 works in 58 publications in 1 language and 1,428 library holdings
Genres: Periodicals 
Roles: Editor, Author, Other
Classifications: QD476, 547.1
Publication Timeline
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Most widely held works about Saul G Cohen
 
Most widely held works by Saul G Cohen
Progress in physical organic chemistry( )

in English and held by 736 WorldCat member libraries worldwide

Progress in physical organic chemistry by Saul G Cohen( )

10 editions published between 1963 and 2009 in English and Undetermined and held by 227 WorldCat member libraries worldwide

Hammett Memorial Lecture (J. Shorter). Thermodynamics of Molecular Species (E. Grunwald). Reaction Coordinates and Structure-Energy Relationships (E. Grunwald). Theoretical Studies of the Effects of Hydration on Organic Equilibria (R. Topsom). Y x Scales of Solvent Ionizing Power (T. Bentley & G. Llewellyn). Correlation Analysis of Acidity and Basicity: From the Solution to the Gas Phase (J-F. Gal & P-C. Maria). Correlation Analysis in Organic Crystal Chemistry (T. Krygowski). Author Index. Subject Index. Cumulative Index, Volumes 1 to 17
Progress in physical organic chemistry( )

8 editions published in 1963 in English and held by 204 WorldCat member libraries worldwide

Progress in physical organic chemistry( )

7 editions published in 1964 in English and held by 185 WorldCat member libraries worldwide

Progress in physical organic chemistry by Saul G Cohen( )

15 editions published between 1963 and 2009 in English and Undetermined and held by 57 WorldCat member libraries worldwide

A critical review of topics in physical organic chemistry, this covers the effects of structure and environment on reaction rates and equilibria, mechanisms of reactions, and applications of statistical and quantum mechanics to organic compounds and reactions
Acetylcholinesterase and Acetylcholine Receptor( )

5 editions published between 1985 and 1992 in English and held by 5 WorldCat member libraries worldwide

We are studying the properties of the active site, and the region peripheral to it, of acetylcholinesterase (AcChE), the enzyme which hydrolyzes and thus terminates the action of the important neurotransmitter acetylcholine (AcCh). We have studied the response of the enzyme to synthesized substrates and inhibitors of varied structure for indications about the parts of the enzyme that are complementary to these substrates. From this information radioactive active-site-directed irreversible inhibitors have been designed for use in labeling amino acids in the active site. In this work AcChE was isolated from Torpedo nobiliana. Novel uncharged reversible inhibitors were also prepared for study of their action on the AcCh receptor by Professor J.B. Cohen, Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis
Asymmetric Hydrolysis of Diethyl Acetamidomalonate by Chymotrypsin by Saul G Cohen( )

1 edition published in 1959 in English and held by 2 WorldCat member libraries worldwide

Physical organic chemistry by S G Ed Cohen( Book )

1 edition published in 1964 in Undetermined and held by 1 WorldCat member library worldwide

Progress in physical organic chemistry( Book )

in English and held by 1 WorldCat member library worldwide

Labeling by 1-bromo-2-14C-Pinacolone of His-440 and Trp-435 in Acetylcholinesterase from Electrophorous Electricus( Book )

1 edition published in 1993 in English and held by 1 WorldCat member library worldwide

Acetylcholinesterase (AcChE), isolated from electric organ of E. electricus, was characterized by SDS-PAGE, titration with 7-(dimethylcarbamoyloxy)-N-methylquinolinium and hydrolysis of AcCh and AcSCh. Peptide labeled by 3(H)dfp was isolated and sequenced from Gln-193 to Arg-216, with label at Ser-200, 83% homologous with that deduced for T. californica, with Gln-193, Ala-203, Leu-210, and Asp-214 in place of thr, Gly, Ile and Gly, respectively. (3H)DFP labeled peptide of T. nobiliana AcChE was identical to that of T. californica. Inactivation of AcChE from E. electricus by 1-bromo-2-(14C)pinacolone (14C)BrPin) led to two labeled peptides sequenced from Ala-427 to Leu-450, identical to that deduced for T. californica, one with 14C release indicating label at active-site His-440, protected by 5-trimethylammonio-2-pentanone (TAP), the other, not protected by TAP, with label apparently at Trp-435. Label was also found at two extra-active-site residues where alkylation may lead to decreased activity. In contract, (14C)BrPin inactivates and labels AcChE from T. nobiliana by reaction with Cys-231, a residue not present in E. electricus. With both AcChEs inactivation by BrPin prevents reaction with (3H)DFP, and prior inactivation by DFP does not prevent reaction with (14C)BrPin
to Lewis Mumford by Brandeis University( )

in English and held by 1 WorldCat member library worldwide

Correspondence to Lewis Mumford from various administrators of Brandeis University
 
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Progress in physical organic chemistry
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English (52)