Silva, Alcino Jose Roriz Teixeira da 1961-

Overview

Works:	31 works in 63 publications in 2 languages and 1,729 library holdings
Genres:	Conference papers and proceedings Interviews Internet videos
Roles:	Author, Actor, Other, Editor, Contributor

Publication Timeline

Most widely held works about Alcino Jose Roriz Teixeira da Silva

Learning and Memory - A Conversation With Alcino Silva by Howard Burton( )
Ideas Roadshow : Learning and Memory( Visual )
Ideas Roadshow : Learning and Memory( Visual )
Ideas roadshow. a conversation with Alcino Silva( Visual )
Learning and Memory (Part II): A Conversation with Alcino Silva( Visual )

Most widely held works by Alcino Jose Roriz Teixeira da Silva

Engineering the next revolution in neuroscience : the new science of experiment planning by Alcino Jose Roriz Teixeira da Silva( )

13 editions published between 2013 and 2014 in English and held by 971 WorldCat member libraries worldwide

This title presents a framework for accelerating discovery in neuroscience. Deriving principles directly from detailed case studies, the authors show how maps of research findings will enable researchers to see what their field has accomplished and where the unexplored territories still reside

Memories : molecules and circuits by B Bontempi( )

18 editions published in 2007 in English and held by 495 WorldCat member libraries worldwide

Provides an integrative view of molecular, cellular, and systems level mechanisms underlying cognitive processes in both animals and humans. This book also discusses the state-of-the-art and future avenues, along with an overview of the underlying neurobiology of cognitive processes from a basic science standpoint

Ideas roadshow. a conversation with Alcino Silva( Visual )

1 edition published in 2015 in English and held by 11 WorldCat member libraries worldwide

In the first of a special two-part discussion with Alcino, we discuss his epistemological motivations, how neuroscience works in the lab, the progress we've made towards understanding learning and memory on a molecular level and why neurons are just like teenagers

Memory( Visual )

1 edition published in 2021 in English and held by 11 WorldCat member libraries worldwide

MEMORY presents clips of five different experts (Lisa Feldman Barrett, Alcino Silva, Fred Gitelman, Elizabeth Loftus, Matthew Walker) highlighting various aspects of memory, from cutting-edge neuroscience experiments on animal models to how an intense exposure to the card game bridge can naturally result in remarkable feats of memory

Learning and memory. a conversation with Alcino Silva( Visual )

2 editions published in 2015 in English and held by 5 WorldCat member libraries worldwide

In the first of a special two-part discussion with University of California, Los Angeles geneticist Alcino Silva, we discuss his epistemological motivations, how neuroscience works in the lab, the progress we've made towards understanding learning and memory on a molecular level and why neurons are just like teenagers

Learning and memory. a conversation with Alcino Silva( Visual )

2 editions published in 2015 in English and held by 5 WorldCat member libraries worldwide

In this second part of the discussion with University of California, Los Angeles geneticist Alcino Silva, we discuss "smart mice", implanting memories, Alcino's liberating discovery that cognitive deficits associated with developmental disorders can be reversed, the importance of "research maps" for the field and inspired optimism for the future

Randomised controlled trial of simvastatin treatment for autism in young children with neurofibromatosis type 1 (SANTA) by SANTA Consortium( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Adult reversal of cognitive phenotypes in neurodevelopmental disorders by Alcino Jose Roriz Teixeira da Silva( )

1 edition published in 2009 in English and held by 2 WorldCat member libraries worldwide

Memory formation depends on both synapse-specific modifications of synaptic strength and cell-specific increases in excitability by John Lisman( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

All the light that we can see: a new era in miniaturized microscopy by Daniel Aharoni( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory by Adam C Frank( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies by Jacqueline N Crawley( )

1 edition published in 1997 in English and held by 2 WorldCat member libraries worldwide

MAPK Signaling Determines Anxiety in the Juvenile Mouse Brain but Depression-Like Behavior in Adults( )

1 edition published in 2012 in English and held by 2 WorldCat member libraries worldwide

Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes by Joana Gonçalves( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

Memories: Molecules and Circuits : Molecules and Circuits by Bruno Bontempi( )

1 edition published in 2007 in English and held by 1 WorldCat member library worldwide

Memories are made of this by Dean Martin( Visual )

1 edition published in 1993 in English and held by 1 WorldCat member library worldwide

The illusive nature of memory is discussed in this Equinox documentary. Thirty people recount their earliest memories in an experiment to find out how much most people remember before the age of three. Before the age of two, barely nothing is remembered. Caroline Rovee Collier describes her research into babies' memories and other aspects of children's memory is shown as a child's capacity for remembering grows through the years. Where are memories stored and how is it that we can often only remember things when the memory is triggered by something. James McGaugh describes how there are probably different memory systems within the brain and Silva Alcino talks about spatial memory. People with particular memory problems are shown. Kerry has had some damage to her temporal lobes and suffers from amnesia and word deficiencies. Geoffrey can not turn short term memory into his long term memory store following a viral illness. His IQ remains the same and strangely, since his illness he has become very good at playing table tennis, which requires strong motor memory skills. The programme ends with an account by Gary Lynch of his recent research into the chemicals that are involved in memory

Noonan syndrome-associated SHP2 mutation differentially modulates the expression of postsynaptic receptors according to developmental maturation( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Highlights: A Noonan syndrome-associated mutation in SHP2 increases NMDA receptor expression in premature neurons. This mutation increases the size of AMPA receptor clusters in early maturing neurons. The SHP2 mutation also increases both the size and the number of AMPA receptor clusters in mature neurons. The altered expressions of glutamate receptors by mutant SHP2 can be reversed by inhibiting the MAPK signaling pathway. Abstract: Glutamate is the major excitatory neurotransmitter in the central nervous system, and related signaling involves both AMPA and NMDA subtype receptors. The expression of glutamate receptors is dynamically regulated during development. Recent studies showed that the dysregulation of glutamate receptor expression and function is associated with neurodevelopmental disorders including intellectual disability. Previously, a Noonan syndrome (NS)-associated SHP2 mutation (SHP2 D61G) was shown to increase the synaptic delivery of AMPA receptor, subsequently impairing synaptic plasticity and learning in adult mice. However, how the mutant SHP2 affects glutamate receptor expression during development is not known. Here, we found that the SHP2 D61G differentially regulates the expression of AMPA and NMDA receptors depending on the stage of neuronal maturation. In cultured neurons (immature stage; DIV 6), overexpression of SHP2 D61G significantly increased the average size and the number of NMDA receptor-containing particles, but not those with AMPA receptors. In early matured neurons (DIV 12), SHP2 D61G significantly increased only the average size of AMPA receptor particles, and subsequently increased their number in matured neurons (DIV 18). Importantly, all the changes described above for SHP2 D61G neurons were reversed by inhibiting MAPK. These data demonstrate that the increased activation of MAPK signaling pathway by SHP2 D61G could deregulate the surface expression of synaptic receptors during neuronal development, which likely contributes to cognitive impairments in NS patients

Misterna sieć pamięci by Alcino Jose Roriz Teixeira da Silva( )

1 edition published in 2017 in Polish and held by 1 WorldCat member library worldwide

Adult reversal of cognitive phenotypes in neurodevelopmental disorders by Alcino Jose Roriz Teixeira da Silva( )

1 edition published in 2009 in English and held by 1 WorldCat member library worldwide

Recent findings in mice suggest that it is possible to reverse certain neurodevelopmental disorders in adults. Changes in development, previously thought to be irreparable in adults, were believed to underlie the neurological and psychiatric phenotypes of a range of common mental health problems with a clear developmental component. As a consequence, most researchers have focused their efforts on understanding the molecular and cellular processes that alter development with the hope that early intervention could prevent the emergent pathology. Unexpectedly, several different animal model studies published recently, including animal models of autism, suggest that it may be possible to reverse neurodevelopmental disorders in adults: Addressing the underlying molecular and cellular deficits in adults could in several cases dramatically improve the neurocognitive phenotypes in these animal models. The findings reviewed here provide hope to millions of individuals afflicted with a wide range of neurodevelopmental disorders, including autism, since they suggest that it may be possible to treat or even cure them in adults

Molecular and cellular mechanisms underlying the cognitive deficits associated with neurofibromatosis 1 by Rui Costa( )

1 edition published in 2002 in English and held by 1 WorldCat member library worldwide