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Pew Scholars Program in the Biomedical Sciences

Overview
Works: 198 works in 199 publications in 1 language and 199 library holdings
Genres: Interviews  Biography  Oral histories  Abstracts 
Publication Timeline
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Most widely held works about Pew Scholars Program in the Biomedical Sciences
 
Most widely held works by Pew Scholars Program in the Biomedical Sciences
Oral history interview with James U. Bowie by James Ulrich Bowie( )

1 edition published in 1999 in English and held by 1 WorldCat member library worldwide

James U. Bowie was born in Rochester, Minnesota. He discovered biology and proteins while working at the Mayo Clinic, where his father worked.. Bowie received his BA from Carleton College, then spent a year as a lab technician, which convinced him against attending medical school. He attended Michigan Institute of Technology for his Ph.D instead. Next, he accepted a postdoc in chemistry and biochemistry at University of California, Los Angeles, where he focused on analyzing the sequence and structure of proteins through computational biology and on the use of computer programming to predict protein structure. He also developed an interest in characterizing the structure, function, and regulation of human cell membrane proteins. Bowie is now a faculty member at UCLA
Oral history interview with Yue Xiong by Yue Xiong( )

1 edition published in 2000 in English and held by 1 WorldCat member library worldwide

Yue Xiong was born in Nanchang, in Jiang Xi province, in the southern part of China, the eldest of three siblings (he has two younger sisters). His father was a forestry scholar who was sent to a labor camp during the Cultural Revolution. When Xiong’s father was finally allowed to return to his family, he was assigned to Nanhu, where Xiong lived until he left for college. After he finished high school Xiong worked on the farm where his family lived and taught elementary and junior high school. When the Cultural Revolution ended and the colleges reopened Xiong was able to take the entrance exam and finally to attend college. He matriculated at Fudan University, which impacted both his farm and his community, pursuing a broad education until deciding to become a scientist. Xiong entered graduate school in the lab of San-Chiun Shen, at which time he found molecular biology in China to be out of sync with the performance of science elsewhere. Nevertheless, he had a keen interest in learning modern molecular genetics, and James Watson's book on the molecular biology of the gene had a great impact on him; he worked with David Ow on a nitrogen-fixation gene. Interested in the China-United States Biochemistry Examination and Application program (CUSBEA), Xiong spent time at the Guangzhou English Learning Center (GELC). Subsequently, Xiong's CUSBEA application to the University of Rochester was accepted, and on Dr.Shen’s advice he went there. Transitioning to American culture took time, but he soon entered Thomas Eickbush’s laboratory researching DNA sequencing and transposable elements of the chorea gene. Xiong helped develop the mild-extracting method for isolating linealized and supercoiled DNA and he also worked on the evolution of transposable elements and the analysis of reverse transcriptase. He considered several postdoctoral positions, including one with Harold Varmus, though finally decided to accept an offer in David Beach’s lab at Cold Spring Harbor Laboratory in New York. He participated in a genetic approach to isolate G1 cyclinin mammalian cells; helped discover cyclin gene activation during the G1 phase; and studied the effect of p21 and CDKon cyclin. From Cold Spring Harbor he accepted a position at University of North Carolina at Chapel Hill looking at cell-cycle control and tumor suppression
Oral history interview with Stephen L. Johnson by Stephen L Johnson( )

1 edition published in 2002 in English and held by 1 WorldCat member library worldwide

Stephen L. Johnson was raised in Nashville, Tennessee, the middle (with his twin brother) of four children, growing up in the pre- and post-Civil Rights Era. His father received his degree in electrical engineering and taught in that discipline at Vanderbilt University, though he also pursued a degree in divinity; his mother was a trained psychologist. Johnson partook in the normal activities of childhood, including Boy Scouts and music, but he had a very high affinity for and interest in writing. He matriculated at Vanderbilt University with the intention of becoming a writer. After deciding against becoming a novelist, Johnson's interest in science was piqued while working in Lee Limbird's pharmacology lab, though he still had some trepidation about whether or not science actually suited him. Ultimately he decided to pursue science and was accepted into the genetics department at the University of Washington, Seattle, where he worked under Breck Byers on fusing Cdc4 and LAC-Z genes in yeast. While at Washington he was also fortunate to be mentored by Nobel laureate Leland H. Hartwell. Upon finishing his graduate studies Johnson decided to remain in the Northwest and began to work on zebrafish with James A. Weston and Charles A. Kimmel at the University of Oregon, Eugene. While there he worked on tissue regeneration mutants, pigment patterns, isometric growth, and genetic mapping, and he developed inbred strains and centromere markers for mapping the zebrafish genome. Johnson then accepted a position at Washington University School of Medicine to continue his work
Oral history interview with Tatsuya Hirano by Tatsuya Hirano( )

1 edition published in 2002 in English and held by 1 WorldCat member library worldwide

Tatsuya Hirano was born and raised in Chiba, Japan. Hirano’s childhood, according to him, was rather typical; he had an early interest in the arts (he liked drawing and carpentry). He excelled in school and decided to pursue a college education in science. He entered Kyoto University intending to study physics, but interest in contemporary advances in molecular biology pulled him much more in that direction. Hirano remained at Kyoto University and worked in Mitsuhiro Yanagida’s laboratory on the genetics of chromosome structure in fission yeast. Since there were no postdoctoral positions available in Japan, and even fewer faculty positions, Hirano decided, like many of his fellow graduate students, to undertake a postdoctoral fellowship abroad. Wanting to broaden his experience in his field, Hirano decided that he wanted to work in the United States and chose to study with Timothy J. Mitchison—someone Hirano considered one of the brightest cell biologists of his age—at the University of California, San Francisco. Hirano worked on chromosome condensation and the condensin complex in Mitchison’s lab, all the while adjusting to American life and culture. From there, he accepted a position at the Cold Spring Harbor Laboratory in New York, where he continued his research on condensin and cohesion
Oral history interview with Samuel L. Pfaff by Samuel Pfaff( )

1 edition published in 2005 in English and held by 1 WorldCat member library worldwide

Samuel L. Pfaff was born and raised in Rochester, Minnesota. He received a public education and felt fortunate to have a fifth grade teacher who recommended him for accelerated academic work and to have a high school biology teacher who suggested he volunteer in a Mayo Clinic laboratory, subsequently contacting Dr. Peter Dyck at Mayo on Pfaff’s behalf. In Dyck’s neurology lab, Pfaff contributed to Dr. Jeff Yao’s research on Wallerian degeneration (the degeneration of nerves after injury); he presented his work at local, state, and, finally, National Science Fairs and because of it also won awards from the U.S. Navy and the state of West Virginia to attend a navy-themed camp in Hawaii and a science camp in West Virginia. He decided to attend a local college for his undergraduate degree, matriculating at Carleton College—a liberal arts school about forty minutes from his home. Dr. Ross Shoger’s class in developmental biology proved quite influential and Pfaff chose to pursue a doctoral degree in the sciences over a medical degree. He entered the University of California system for graduate school, studying at Berkeley with Peter Duesberg whose lab focused on how oncogenes function—working with retroviruses, RNA viruses, that could be grown on cells (mostly on chick embryos) which then led to a transformation of the cells and over proliferation—though this was slightly before Duesberg’s public claims that the Human Immunodeficiency Virus (HIV) was not the cause of Acquired Immune Deficiency Syndrome (AIDS). From Berkeley Pfaff went on to undertake a postdoctoral fellowship in developmental molecular biology with William Taylor at Vanderbilt University in Nashville, Tennessee, and then another with Thomas M. Jessell at Columbia University in New York, New York, working on molecular neurobiology and gene regulation of motor neuron development. After his postdoc he moved on to a position at the Salk Institute for Biological Studies in La Jolla, California, researching gene combinations for regulation of motor neurons in spinal cord development
Oral history interview with Roberta A. Gottlieb by Roberta A Gottlieb( )

1 edition published in 2003 in English and held by 1 WorldCat member library worldwide

Roberta A. Sanchez Gottlieb grew up on a cattle ranch about eighty miles from Albuquerque, New Mexico. She was heavily influenced by her parents who valued education and curiosity, and had several influential teachers in school who contributed to her intellectual development. After graduating from high school as valedictorian, Gottlieb matriculated at Bryn Mawr College. Almost immediately upon entering, however, she decided that she wanted to undertake more rigorous scientific research and so she transferred (after one semester) to Johns Hopkins University. While an undergraduate Gottlieb undertook biophysical research with Michael Beers, focusing on electron microscopy. Based on this experience she developed an interest in microtubule assembly, leading her to work with Douglas B. Murphy during her junior year. She decided to attend the Johns Hopkins University School of Medicine for her medical degree, conducting research on the MAP-2 protein. Marrying during medical school presented Gottlieb with the “two-body problem” for her residency (her husband was also a physician). They chose the University of Texas Health Science Center in Houston, where she completed a residency in pediatrics and a hematology-oncology fellowship under William J. Lennarz and Eugenie S. Kleinerman on immune response and protein kinase C inhibition; she also worked with Steven Buescher on neutrophils in the department of infectious diseases. After residency Gottlieb began a postdoctoral position with Michael Karin in molecular biology at the University of California, San Diego and subsequently took another postdoctorate with Bernard M. Babior, where she was able to indulge her interest in apoptosis. She then moved on to a position at the Scripps Research Institute
Oral history interview with Erol Fikrig by Erol Fikrig( )

1 edition published in 2000 in English and held by 1 WorldCat member library worldwide

Erol Fikrig was born in Istanbul, Turkey. The family moved to Queens, New York, when Fikrig was a child. Fikrig attended Cornell University, majoring in chemistry. He decided early, influenced by both his father and his college roommate, to go to medical school. He attended Cornell’s Weill School of Medicine. During his third and fourth years he studied in Brazil, where he became interested in vector-borne diseases. Interested in infectious disease and internal medicine, he did his residency at Vanderbilt University. Next, he became a fellow at Yale, where he worked in Richard Flavell’s laboratory. He was offered an assistant professorship in rheumatology at Yale, eventually becoming full professor. Fikrig continues to study Lyme disease and other related diseases
Oral history interview with Lynn Cooley by Lynn Cooley( )

1 edition published in 1996 in English and held by 1 WorldCat member library worldwide

Lynn Cooley grew up in Portland, Connecticut. Cooley matriculated into Connecticut College, where she majored in zoology. She also took a semester off to take a course at the Woods Hole Marine Biological Laboratory, which led to her participation on a research cruise. She applied to graduate schools, entering the University of Texas, where she persuaded Kwan Wang to take her into his lab to work on cytoskeletal proteins. Wanting to return to the East Coast, she transferred to Dieter Söll’s lab at Yale University, where he later suggested she complete her Ph.D. at the University of Texas while conducting research in his lab. Cooley then accepted a post doc appointment in Allan Spradling’s lab at the Carnegie Institution of Washington in Baltimore, Maryland, where she began researching the regulation of expression in follicle cells. She also developed a focus on the kelch and chickadee genes. This research continued when Cooley started her own lab at the Yale School of Medicine, in conjunction with students Feiyu Xue and Esther Verheyen. The lab’s research divided into two components: genes related to the function of ring canals and genes related to the regulation of actin in nurse cells
Oral history interview with Jonathan M. Horowitz by Jonathan Michael Horowitz( )

1 edition published in 1998 in English and held by 1 WorldCat member library worldwide

Jonathan M. Horowitz was born in Brooklyn, New York. By high school he had decided become a researcher in molecular biology, like Francis Crick. He attended a high school with no grades; he even designed his own courses. Hearing about its unstructured curriculum, he attended Brown University, but struggled to do well. For graduate school, Horowitz attended the University of Wisconsin, where he worked in Rex Risser’s lab on mouse retroviruses. Shifting to oncogenes, he next joined Robert Weinberg’s lab at the Whitehead Institute for Biomedical Research. In collaboration with Edward Harlow, Horowitz discovered Rb is an E1A-binding protein and mapped the E1A- binding region on Rb. He is now at North Carolina State College of Veterinary Medicine, where he finds much support for his research
Oral history interview with Jochen Buck by Jochen Buck( )

1 edition published in 1998 in English and held by 1 WorldCat member library worldwide

Jochen Buck was born and grew up in Reutlingen, Germany. During the Vietnam War, he became a conscientious objector, working with disabled youths. He decided to become a doctor, but in medical school at the University of Tübingen, he discovered that he loved scientific research. He worked in Ulrich Hammerling's lab, where he localized cell growth caused by autocrine growth factor. He accepted a postdoctoral position at Memorial Sloan-Kettering Cancer Center, working with Vitamin A and discovering retro-retinoids. Next, he accepted an assistant professorship at Cornell University Medical College. He is now an associate at Cornell, where his lab and Lonny Levin's share space and where he and Levin work together on adenylyl cyclase
Oral history interview with Adrian R. Krainer by Adrian Krainer( )

1 edition published in 1997 in English and held by 1 WorldCat member library worldwide

Adrian R. Krainer was born in Montevideo, Uruguay. Political unrest, anti-Semitism, and Zionism framed his teenage years. He attended Columbia University to study biochemistry, finding courses with James A. Lewis and Charles R. Cantor, and research with Catherine L. Squires quite stimulating. While at Harvard for graduate school, Krainer worked with Thomas P. Maniatis, developing a system for cell-free RNA splicing, which enabled them to elucidate the mechanisms of human pre-mRNA splicing. He took an independent fellow position at Cold Spring Harbor Laboratory, mentored by Richard J. Roberts, and began to characterize snRNP and protein components of the splicing machinery, before accepting a faculty position there in 1989
Oral history interview with David E. Fisher by David E Fisher( )

1 edition published in 2001 in English and held by 1 WorldCat member library worldwide

David E. Fisher grew up in Highland Park, New Jersey. Deciding to pursue a career in medicine, he attended the Curtis Institute of Music and Swarthmore College concurrently. He spent his first college summer in his father's lab and published his first paper. He also worked in Robert Weinberg's lab at Massachusetts Institute of Technology, where he discovered molecular biology and oncology. Interested in lab work, he received an MD/Ph.D. at Weill Medical College of Cornell University and Rockefeller University. In Günter Blobel's laboratory he completed thesis projects on systemic lupus erythematosis and T-cells. He talks about funding, teaching, and minority and women students and faculty at Harvard University. His current research is on apoptosis and on microphthalmia transcription factor (Mitf) in melanocytes and osteoclasts
Oral history interview with Robert D. Nicholls by Robert D Nicholls( )

1 edition published in 1997 in English and held by 1 WorldCat member library worldwide

Robert D. Nicholls was born in a small town near Melbourne, Australia, one of four children. His father was in the Forests Commission, so the family moved fairly often until Robert's parents divorced when he was a teenager, at which time Mrs. Nicholls and the children moved to Inverloch, a town near the ocean. Though they moved often, they stayed within Victoria, and all the towns they lived in were small. As a result, Nicholls grew up loving the countryside and animals. He and his brother collected and raised frogs and tortoises. Schools were of variable quality; his last year in high school turned out to have some very good teachers for his interests, already science and medicine. He attributes his interest in part also to his sister's illness, which kept her in hospital for six or seven years when she was a child
Oral history interview with Fenyong Liu by Fenyong Liu( )

1 edition published in 2005 in English and held by 1 WorldCat member library worldwide

Fenyong Liu was born and raised in Guangzhou, China during the Cultural Revolution. After passing the university entrance examinations, Liu matriculated at the prestigious University of Science and Technology of China. Initially he decided to pursue physics, but then transferred to the biology program after two years of study. Encouraged by his professors, Liu decided to attend graduate school in the United States at the University of Chicago, briefly spending time in the Medical School before transferring into the Biochemistry and Molecular Biology program, where he worked with Richard Roller and Bernard Roizman. While his initial research focused on the biochemistry of viral DNA replication, Liu focused in the last years of his doctoral study on the genetics of the herpes virus capsid protein; his research resulted in a patent and created intense interest from the pharmaceutical industry
Pew reunion, Puerto Vallarta, Mexico, January 8-13, 2000( Book )

1 edition published in 2000 in English and held by 1 WorldCat member library worldwide

Oral history interview with Jason G. Cyster by Jason G Cyster( )

1 edition published in 2002 in English and held by 1 WorldCat member library worldwide

Jason G. Cyster was born in Western Australia. In high school, he obtained the highest aggregate score on Australia’s Tertiary exams in his state, receiving the Beazley Award. He decided to study biology based upon his childhood interests in animals and the caliber of lecturers at Western Australia University. By his third year, he became interested in immunology and began working with Wayne R. Thomas. After receiving a Commonwealth Overseas Studentship, Cyster attended Oxford University, where he worked with Alan F. Williams characterizing the CD43 molecule and collaborated with Paul C. Driscoll and Ian Campbell on a structural analysis of the T lymphocyte CD2 antigen. After a postdoc at Stanford, he accepted a position at the University of California, San Francisco, where he is today
Oral history interview with Michael A. Caudy by Michael Allen Caudy( )

1 edition published in 1996 in English and held by 1 WorldCat member library worldwide

Michael A. Caudy was born in Columbus, Ohio. When he was in high school, he worked as a technician in the veterinary pathology lab at Ohio State University, and later attended university there. He received a degree in English education and taught elementary and junior high school for a number of years while maintaining an interest in science, leading him to enter the biophysics graduate program at Ohio State. After a year, he transferred to the University of California, Berkeley, to David Bentley's lab, to study theoretical biophysics and neurobiology. He then accepted a position at Weill Cornell Medical College, where he works today, researching mammalian and Drosophila genetics. He discusses the college's atmosphere, pressures on medical schools, his research agenda, and his lab
Oral history interview with Philip B. Wedegaertner by Philip B Wedegaertner( )

1 edition published in 2003 in English and held by 1 WorldCat member library worldwide

Philip B. Wedegaertner grew up in Stockton, California. Wedegaertner enjoyed reading, playing sports (he joined the wrestling team in high school), and camping (he became an Eagle Scout in the Boy Scouts of America). He met the woman who later became his wife in high school through church activities; he always did well in school, liking mathematics and the sciences, but was unsure of what career he wanted to pursue. He matriculated at the University of California, Davis with an undeclared major for his first two years there; subsequently he majored in biochemistry with a minor in history. During the summer of his junior year Wedegaertner worked with James W. Blankenship in the School of Pharmacy at University of the Pacific; during his senior year he worked closely with a graduate student in Donald M. Carlson’s laboratory on various independent projects. After completing his undergraduate degree, Wedegaertner decided to remain on the West Coast and pursue graduate work in biochemistry at the University of California, San Diego. There he worked with Gordon N. Gill—after developing an interest in signal transduction—synthesizing and characterizing the tyrosine kinase domain of the epidermal growth factor receptor. Wedegaertner then decided to go abroad and took a short-term postdoctoral fellowship with Claude Cochet, who had worked with Gill, in Grenoble, France; then he returned to the United States and studied with Henry R. Bourne at the University of California, San Francisco, focusing on lipid modifications of G proteins. At the end of his postdoctoral studies, Wedegaertner accepted a position at Thomas Jefferson University in Philadelphia, Pennsylvania, continuing work on G proteins
Oral history interview with Manfred Frasch by Manfred Frasch( )

1 edition published in 1998 in English and held by 1 WorldCat member library worldwide

Manfred Frasch was born in Holzgerlingen, Germany. He had an early curiosity about how things work, leading him to chemistry and biology. He entered the University of Tübingen, where he studied biochemistry. His diploma thesis concerned gene regulation in Drosophila, which he continued to study through his career. Liking the projects and atmosphere of Tübingen, Frasch stayed for his Ph.D. He learned cloning techniques and decided to pursue genetic approaches. Wanting to see more of the world, he took a postdoc in Michael Levine's lab at Columbia University, working on the even-skipped gene. After a fellowship at the Max Planck Institute, he accepted a position at Mount Sinai School of Medicine in New York City, where he established his lab and is now a tenured professor
Oral history interview with Carolyn R. Bertozzi by Carolyn R Bertozzi( )

1 edition published in 2003 in English and held by 1 WorldCat member library worldwide

Carolyn Bertozzi grew up in Lexington, Massachusetts, the second of three girls. Her father was a nuclear physicist at the Massachusetts Institute of Technology, her mother a secretary in MIT’s physics department. Carolyn was recruited to Harvard. She began as a biology major but in her second year took an organic chemistry class, which she loved, although she continued to take biology classes, she switched her major to chemistry. She was first in her class and eventually graduated summa cum laude, but Harvard’s chemistry department was exclusively male at the time. As a result, she went to a lab in the biochemistry department, where Joseph Grabowski, her teacher for a physical organic chemistry class, asked her to work for him during the summer. He convinced her to go to graduate school at University of California at Berkeley. At Berkeley, she joined Mark Bednarski’s bioorganic chemistry laboratory to study carbohydrates. She wrote her doctoral dissertation on the synthesis of carbohydrate analogues for biological applications. Carolyn went to work in Steven Rosen’s cell biology laboratory at the University of California, San Francisco, for her postdoc. There she studied the role of carbohydrates in inflammation and leukocyte adhesion. After her postdoctoral work, she accepted an assistant professorship at the University of California at Berkeley and set up her own laboratory. She and Rosen also founded a private company, Thios Pharmaceuticals, Inc
 
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English (24)