WorldCat Identities

Gophna, Uri

Overview
Works: 11 works in 31 publications in 2 languages and 841 library holdings
Roles: Editor, Author, Contributor
Publication Timeline
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Most widely held works by Uri Gophna
Beneficial microorganisms in multicellular life forms by Eugene Rosenberg( )

10 editions published between 2011 and 2014 in English and held by 438 WorldCat member libraries worldwide

"All animals and plants form associations with hundreds or thousands of different beneficial microorganisms. These symbiotic microbes play an important role in the development, adaptation, health and evolution of their hosts. This book brings together a group of diverse biologists to discuss microbial interactions with multicellular life forms including insects, corals, plants and mammals, including humans. The various mechanisms by which microorganisms benefit their hosts are discussed, including providing essentials nutriments, preventing disease, inducing the immune system, and combating stress. Scince the microbiota can be transferred from parent offspring, it plays an important role in the origin and evolution of animal and plant species. This book should be of interest to the widest range of biological scientists, merging the studies of host and microbial physiology, symbiosis, and the ecology and evolution of symbiotic partners."
Lateral gene transfer in evolution by Uri Gophna( )

11 editions published between 2013 and 2015 in English and held by 394 WorldCat member libraries worldwide

"Although the phenomenon of lateral gene transfer has been known since the 1940s, it was the genomics era that has really revealed the extent and many facets of this evolutionary/genetic phenomenon. Even in the early 2000s with but a handful of genomes available, it became clear that the nature of microorganisms is full of genetic exchange between lineages that are sometimes far apart. The years following this saw an explosion of genomic data, which shook the "tree of life" and also raised doubts about the most appropriate species concepts for prokaryotes. This book represents the manyfold contributions of LGT to the evolution of micro and, to an extent, macroorganisms by focusing on the areas where it has the largest impact: metabolic innovations and adaptations and speciation."
CEACAM1 recognition by bacterial pathogens is species-specific by Maike Voges( )

2 editions published between 2010 and 2011 in German and English and held by 2 WorldCat member libraries worldwide

Oscillospira: a Central, Enigmatic Component of the Human Gut Microbiota( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Abstract : Oscillospira is an enigmatic bacterial genus that has never been cultured, but is constantly detected by 16S rRNA gene surveys of the human microbiome. Here we summarize recent evidence that Oscillospira is positively associated with leanness and health, speculate about its physiology, and argue its potential importance for human health
Finally, Archaea Get Their CRISPR-Cas Toolbox( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Abstract : The majority of archaea encode CRISPR-Cas systems but only a few CRISPR-Cas-based genetic tools have been developed for organisms from this domain. Nayak and Metcalf have harnessed a bacterial Cas9 protein for genome editing in Methanosarcina acetivorans, enabling efficient gene deletion and replacement
DNA as a phosphate storage polymer and the alternative advantages of polyploidy for growth or survival by Karolin Zerulla( )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

Distinct Microbiotas are Associated with Ileum-Restricted and Colon-Involving Crohn's Disease( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Abstract : Background: The etiology of inflammatory bowel disease is believed to involve a shift in the microbiota toward more proinflammatory species. Crohn's disease (CD) usually manifests as one of three phenotypes, involving inflammation of the terminal ileum, the colon, or both. However, what determines the particular phenotype and the level of disease activity remains unknown. In this study, we aim to characterize the intestinal microbiota associated with different CD phenotypes. Methods: DNA was extracted from biopsies of 31 patients with ileal, ileocolic, or colon-restricted CD, and also from 5 non–inflammatory bowel disease control subjects, and analyzed by 16S rRNA gene amplicon pyrosequencing. Data were processed using the Quantitative Insights Into Microbial Ecology pipeline and analyzed using linear discriminant analysis with effect size estimation and PICRUSt algorithms. Two additional recently published cohorts were also analyzed in this study. Results: Highly significant separation was observed between bacterial composition of ileal CD compared with CD with colonic involvement (genus level Bray–Curtis P = 0.005, R = 20%). This separation was unaffected by the biopsy's location or its inflammatory state, or by the patients' condition (remission or relapse). Faecalibacterium was strongly reduced in ileal CD compared with CD with colonic involvement, whereas Enterobacteriaceae were more abundant in the former. Fusobacterium relative abundance was strongly correlated with disease activity in patients with ileal-involving, but not in colon-involving, CD. Conclusions: Ileal and colon-involving CD sustain distinct microbiotas, suggesting that different mechanisms underlie the two major manifestations of CD. The potential contribution of Fusobacterium to inflammation in ileal CD should be further investigated. Abstract : Article first published online 11 January 2016.Supplemental Digital Content is Available in the Text
Reply( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Abstract : Article first published online 12 April 2016
Virulence factors of septicemic escherichia coli strains by Uri Gophna( Book )

1 edition published in 2003 in English and held by 1 WorldCat member library worldwide

Distinct Microbiotas are Associated with Ileum-Restricted and Colon-Involving Crohn's Disease( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Abstract : Background: The etiology of inflammatory bowel disease is believed to involve a shift in the microbiota toward more proinflammatory species. Crohn's disease (CD) usually manifests as one of three phenotypes, involving inflammation of the terminal ileum, the colon, or both. However, what determines the particular phenotype and the level of disease activity remains unknown. In this study, we aim to characterize the intestinal microbiota associated with different CD phenotypes. Methods: DNA was extracted from biopsies of 31 patients with ileal, ileocolic, or colon-restricted CD, and also from 5 non-inflammatory bowel disease control subjects, and analyzed by 16S rRNA gene amplicon pyrosequencing. Data were processed using the Quantitative Insights Into Microbial Ecology pipeline and analyzed using linear discriminant analysis with effect size estimation and PICRUSt algorithms. Two additional recently published cohorts were also analyzed in this study. Results: Highly significant separation was observed between bacterial composition of ileal CD compared with CD with colonic involvement (genus level Bray-Curtis P = 0.005, R = 20%). This separation was unaffected by the biopsy's location or its inflammatory state, or by the patients' condition (remission or relapse). Faecalibacterium was strongly reduced in ileal CD compared with CD with colonic involvement, whereas Enterobacteriaceae were more abundant in the former. Fusobacterium relative abundance was strongly correlated with disease activity in patients with ileal-involving, but not in colon-involving, CD. Conclusions: Ileal and colon-involving CD sustain distinct microbiotas, suggesting that different mechanisms underlie the two major manifestations of CD. The potential contribution of Fusobacterium to inflammation in ileal CD should be further investigated. Abstract : Article first published online 11 January 2016. Supplemental Digital Content is Available in the Text
Beneficial Microorganisms in Multicellular Life Forms( )

1 edition published in 2011 in English and held by 0 WorldCat member libraries worldwide

 
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Beneficial microorganisms in multicellular life forms
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Alternative Names
Gophna, U.

גופנא, אורי

Languages
English (30)

German (1)