Szunerits, Sabine
Overview
Works: | 61 works in 103 publications in 2 languages and 2,041 library holdings |
---|---|
Roles: | Editor, Author, Thesis advisor, Other, Opponent, 958, Speaker |
Classifications: | QC176.8.P55, 530.44 |
Publication Timeline
.
Most widely held works by
Sabine Szunerits
Nanocarbons for electroanalysis by
Nianjun Yang(
)
9 editions published in 2017 in English and held by 782 WorldCat member libraries worldwide
9 editions published in 2017 in English and held by 782 WorldCat member libraries worldwide
Introduction to plasmonics : advances and applications by
Rabah Boukherroub(
)
12 editions published in 2015 in English and Undetermined and held by 724 WorldCat member libraries worldwide
1. Propagating surface plasmon polaritons / Atef Shalabney -- 2. Different strategies for glycan immobilization onto plasmonic interfaces / Sabine Szunerits and Rabah Boukherroub -- 3. Biophysics of DNA : DNA melting curve analysis with surface plasmon resonance imaging / Arnaud Buhot, Julia Pingel, Jean-Bernard Fiche, Roberto Calemczuk, and Thierry Livache -- 4. Plasmon waveguide resonance spectroscopy : principles and applications in studies of molecular interactions within membranes / Isabel D. Alves -- 5. Surface-wave enhanced biosensing / Wolfgang Knoll, Amal Kasry, Chun-Jen Huang, Yi Wang, and Jakub Dostalek -- 6. Infrared surface plasmon resonance / Stefan Franzen, Mark Losego, Misun Kang, Edward Sachet, and Jon-Paul Maria -- 7. The unique characteristics of localized surface plasmon resonance / Gaetan Leveque and Abdellatif Akjouj -- 8. Advances in the fabrication of plasmonic nanostructures : plasmonics going down to the nanoscale / Thomas Maurer -- 9. Colorimetric sensing based on metallic nanostructures / Daniel Aili and Borja Sepulveda -- 10. Surface-enhanced Raman scattering : principles and applications for single-molecule detection / Diego P. dos Santos, Marcia L.A. Temperini, and Alexandre G. Brolo -- 11. Graphene-based plasmonics / Sinan Balci, Emre Ozan Polat, and Coskun Kocabas -- 12. SPR : an industrial point of view / Iban Larroulet
12 editions published in 2015 in English and Undetermined and held by 724 WorldCat member libraries worldwide
1. Propagating surface plasmon polaritons / Atef Shalabney -- 2. Different strategies for glycan immobilization onto plasmonic interfaces / Sabine Szunerits and Rabah Boukherroub -- 3. Biophysics of DNA : DNA melting curve analysis with surface plasmon resonance imaging / Arnaud Buhot, Julia Pingel, Jean-Bernard Fiche, Roberto Calemczuk, and Thierry Livache -- 4. Plasmon waveguide resonance spectroscopy : principles and applications in studies of molecular interactions within membranes / Isabel D. Alves -- 5. Surface-wave enhanced biosensing / Wolfgang Knoll, Amal Kasry, Chun-Jen Huang, Yi Wang, and Jakub Dostalek -- 6. Infrared surface plasmon resonance / Stefan Franzen, Mark Losego, Misun Kang, Edward Sachet, and Jon-Paul Maria -- 7. The unique characteristics of localized surface plasmon resonance / Gaetan Leveque and Abdellatif Akjouj -- 8. Advances in the fabrication of plasmonic nanostructures : plasmonics going down to the nanoscale / Thomas Maurer -- 9. Colorimetric sensing based on metallic nanostructures / Daniel Aili and Borja Sepulveda -- 10. Surface-enhanced Raman scattering : principles and applications for single-molecule detection / Diego P. dos Santos, Marcia L.A. Temperini, and Alexandre G. Brolo -- 11. Graphene-based plasmonics / Sinan Balci, Emre Ozan Polat, and Coskun Kocabas -- 12. SPR : an industrial point of view / Iban Larroulet
Functionalized nanomaterials for the management of microbial infection : a strategy to address microbial drug resistance by
Rabah Boukherroub(
)
6 editions published between 2016 and 2017 in English and held by 205 WorldCat member libraries worldwide
Front Cover -- Functionalized Nanomaterials for the Management of Microbial Infection -- Copyright Page -- Contents -- List of Contributors -- Preface -- 1 Resistance to Antibiotics and Antimicrobial Peptides: A Need of Novel Technology to Tackle This Phenomenon -- 1.1 Resistance to Antibiotics -- 1.2 Resistance to Bacteriocins Produced by Gram-Positive Bacteria (GPB) -- 1.3 Conclusion and Prospects -- Acknowledgments -- References -- 2 The Role of the Food Chain in the Spread of Antimicrobial Resistance (AMR) -- 2.1 Introduction -- 2.2 AMR in Foodborne Pathogenic Bacteria -- 2.3 AMR in Food-Related Beneficial Microbes -- 2.4 Routes of Transmission of AMR Throughout the Food Chain -- 2.4.1 Foods of Animal Origin -- 2.4.2 Foods of Nonanimal Origin -- 2.4.3 Primary Production and Food Processing Environments and Food Processing Technologies -- 2.4.3.1 Role of Biocides in AMR Acquisition and Spread -- 2.4.3.2 Food Processing Technologies and AMR -- 2.5 Conclusions -- References -- 3 Penetrating the Bacterial Biofilm: Challenges for Antimicrobial Treatment -- 3.1 Introduction -- 3.1.1 Antimicrobial Treatment: In Desperate Need of a Wind of Change -- 3.1.2 The Biofilm Lifestyle -- 3.2 How Biofilms Pose a Challenge to the Diffusion of Antibiotics -- 3.2.1 Mass Transport Phenomena in Biofilms -- 3.2.2 Dense Cell Clusters -- 3.2.3 Binding Interactions Between Antibiotics and Matrix Constituents -- 3.2.3.1 Physicochemical Binding to Matrix Polymers -- 3.2.3.2 Inactivation of Antibiotics by Enzymes Present in the Biofilm Matrix -- 3.3 How to Improve Antibiotic Delivery to Biofilm Cells? -- 3.3.1 Interference With the Biofilm Structure -- 3.3.2 Nanocarriers for Improved Delivery of Antibiotics in Biofilms -- 3.3.2.1 Nanocarriers Protect Antibiotics From Interactions With Biofilm Components
6 editions published between 2016 and 2017 in English and held by 205 WorldCat member libraries worldwide
Front Cover -- Functionalized Nanomaterials for the Management of Microbial Infection -- Copyright Page -- Contents -- List of Contributors -- Preface -- 1 Resistance to Antibiotics and Antimicrobial Peptides: A Need of Novel Technology to Tackle This Phenomenon -- 1.1 Resistance to Antibiotics -- 1.2 Resistance to Bacteriocins Produced by Gram-Positive Bacteria (GPB) -- 1.3 Conclusion and Prospects -- Acknowledgments -- References -- 2 The Role of the Food Chain in the Spread of Antimicrobial Resistance (AMR) -- 2.1 Introduction -- 2.2 AMR in Foodborne Pathogenic Bacteria -- 2.3 AMR in Food-Related Beneficial Microbes -- 2.4 Routes of Transmission of AMR Throughout the Food Chain -- 2.4.1 Foods of Animal Origin -- 2.4.2 Foods of Nonanimal Origin -- 2.4.3 Primary Production and Food Processing Environments and Food Processing Technologies -- 2.4.3.1 Role of Biocides in AMR Acquisition and Spread -- 2.4.3.2 Food Processing Technologies and AMR -- 2.5 Conclusions -- References -- 3 Penetrating the Bacterial Biofilm: Challenges for Antimicrobial Treatment -- 3.1 Introduction -- 3.1.1 Antimicrobial Treatment: In Desperate Need of a Wind of Change -- 3.1.2 The Biofilm Lifestyle -- 3.2 How Biofilms Pose a Challenge to the Diffusion of Antibiotics -- 3.2.1 Mass Transport Phenomena in Biofilms -- 3.2.2 Dense Cell Clusters -- 3.2.3 Binding Interactions Between Antibiotics and Matrix Constituents -- 3.2.3.1 Physicochemical Binding to Matrix Polymers -- 3.2.3.2 Inactivation of Antibiotics by Enzymes Present in the Biofilm Matrix -- 3.3 How to Improve Antibiotic Delivery to Biofilm Cells? -- 3.3.1 Interference With the Biofilm Structure -- 3.3.2 Nanocarriers for Improved Delivery of Antibiotics in Biofilms -- 3.3.2.1 Nanocarriers Protect Antibiotics From Interactions With Biofilm Components
Peroxynitrite detection in biological media : challenges and advances by
Serban Peteu(
)
8 editions published between 2015 and 2016 in English and held by 129 WorldCat member libraries worldwide
Peroxynitrite detection and quantification provides critical information in understanding its biological implications. This book is a timely addition to the literature, as the first in the field, dedicated to detecting this molecule in vivo . It will be welcomed by the community particularly medicinal and analytical chemists, developers of sensors and probes and analytical equipment manufacturers
8 editions published between 2015 and 2016 in English and held by 129 WorldCat member libraries worldwide
Peroxynitrite detection and quantification provides critical information in understanding its biological implications. This book is a timely addition to the literature, as the first in the field, dedicated to detecting this molecule in vivo . It will be welcomed by the community particularly medicinal and analytical chemists, developers of sensors and probes and analytical equipment manufacturers
Transdermal drug delivery by
Sabine Szunerits(
Visual
)
2 editions published in 2019 in English and held by 45 WorldCat member libraries worldwide
2 editions published in 2019 in English and held by 45 WorldCat member libraries worldwide
Chapter Nanoscale Architectures for Smart Bio-Interfaces Advances and Challenges by
Sabine Szunerits(
)
2 editions published in 2011 in Undetermined and English and held by 36 WorldCat member libraries worldwide
2 editions published in 2011 in Undetermined and English and held by 36 WorldCat member libraries worldwide
Nanotechnologies in the fight against coronaviruses by
Sabine Szunerits(
Visual
)
1 edition published in 2020 in English and held by 27 WorldCat member libraries worldwide
1 edition published in 2020 in English and held by 27 WorldCat member libraries worldwide
Nanotechnologies in the fight against coronaviruses by
Sabine Szunerits(
)
1 edition published in 2020 in English and held by 17 WorldCat member libraries worldwide
1 edition published in 2020 in English and held by 17 WorldCat member libraries worldwide
Développement de nano-catalyseurs pour des réactions de couplage C-C by
Emilie Nehlig(
Book
)
4 editions published in 2014 in French and held by 5 WorldCat member libraries worldwide
Ces dernières années, l'intérêt porté à l'obtention de nouveaux systèmes catalytiques a connu un essor fulgurant. Ceci est lié, en particulier, aux applications industrielles variées qui s'étendent de la chimie fine à la chimie pharmaceutique. De nombreux catalyseurs ont ainsi été développés pour un nombre toujours croissant de réactions organiques. Néanmoins, la plupart des catalyseurs homogènes sont difficiles à adapter aux procédés industriels du fait de problèmes de séparation et de régénération. De plus, même efficaces, la plupart des catalyseurs contiennent des métaux nobles, coûteux et difficiles à recycler. C'est pourquoi, de nouveaux protocoles plus économiques et plus respectueux de l'environnement ont besoin d'être recherchés. L'utilisation de nanoparticules magnétiques comme support catalytique en synthèse organique représente une solution innovante pour répondre aux problèmes catalytiques rencontrés. Le but de ce travail consiste à concevoir des nano-catalyseurs magnétiques et à évaluer leur activité catalytique ainsi que leur recyclage pour des réactions de couplage carbone-carbone très utilisées en synthèse organique. Des nanoparticules de Maghémite synthétisées dans en milieux aqueux sont ensuite stabilisées en surface par des agents complexants possédant une fonction terminale qui permettra de les fonctionnaliser avec le catalyseur désiré (L- Proline, peptides, alcaloïde, Palladium). Ces nanomatériaux hybrides, constitués d'un cœur inorganique et d'une couche organique, ont été caractérisés par diverses techniques afin de déterminer leurs propriétés. Leurs activités ont été évaluées sur des réactions de couplage carbone-carbone modèles d'aldolisation, d'addition 1,4 de Michael et la réaction de Suzuki-Miyaura
4 editions published in 2014 in French and held by 5 WorldCat member libraries worldwide
Ces dernières années, l'intérêt porté à l'obtention de nouveaux systèmes catalytiques a connu un essor fulgurant. Ceci est lié, en particulier, aux applications industrielles variées qui s'étendent de la chimie fine à la chimie pharmaceutique. De nombreux catalyseurs ont ainsi été développés pour un nombre toujours croissant de réactions organiques. Néanmoins, la plupart des catalyseurs homogènes sont difficiles à adapter aux procédés industriels du fait de problèmes de séparation et de régénération. De plus, même efficaces, la plupart des catalyseurs contiennent des métaux nobles, coûteux et difficiles à recycler. C'est pourquoi, de nouveaux protocoles plus économiques et plus respectueux de l'environnement ont besoin d'être recherchés. L'utilisation de nanoparticules magnétiques comme support catalytique en synthèse organique représente une solution innovante pour répondre aux problèmes catalytiques rencontrés. Le but de ce travail consiste à concevoir des nano-catalyseurs magnétiques et à évaluer leur activité catalytique ainsi que leur recyclage pour des réactions de couplage carbone-carbone très utilisées en synthèse organique. Des nanoparticules de Maghémite synthétisées dans en milieux aqueux sont ensuite stabilisées en surface par des agents complexants possédant une fonction terminale qui permettra de les fonctionnaliser avec le catalyseur désiré (L- Proline, peptides, alcaloïde, Palladium). Ces nanomatériaux hybrides, constitués d'un cœur inorganique et d'une couche organique, ont été caractérisés par diverses techniques afin de déterminer leurs propriétés. Leurs activités ont été évaluées sur des réactions de couplage carbone-carbone modèles d'aldolisation, d'addition 1,4 de Michael et la réaction de Suzuki-Miyaura
Use of experimental design to empirically model atmospheric corrosion of galvanised steel by
Emilie Dubuisson(
)
1 edition published in 2007 in English and held by 2 WorldCat member libraries worldwide
1 edition published in 2007 in English and held by 2 WorldCat member libraries worldwide
Graphene Oxide Nanosheets for Localized Hyperthermia--Physicochemical Characterization, Biocompatibility, and Induction of
Tumor Cell Death by Malgorzata J Podolska(
)
1 edition published in 2020 in English and held by 2 WorldCat member libraries worldwide
1 edition published in 2020 in English and held by 2 WorldCat member libraries worldwide
Les techniques dérivées de la microscopie à force atomique pour la caractérisation des interconnexions après polissage
mécano-chimique et nettoyage by
Alexandre Dominget(
Book
)
2 editions published in 2007 in French and held by 2 WorldCat member libraries worldwide
Cleaning efficiency and the removal of metallic contaminations have appreciable impact on productivity and reliability. The control of metallic residuals is essential with the implementation of new integration schemes such as self aligned barrier. This study de,.als with the use of two derivative AFM techniques for the characterization of post-CMP and post-CMP cleaned surfaces: the c-AFM for the measurement of surface leakage and the KFM for the measurement of surface potentials and work functions. The first part highlights that the Ta/TaN polishing time has a crucial impact on the surface leakage. The issues observed during the measurements with our experimental conditions will be discussed. KFM analyses show the impact of CMP and post-CMP clean parameters on surface potentials. Work function measurements on post-CMP copper samples show the influence of the passivation layer. The copper work function is reduced, depending on the nature of the passivation layer formed during the immersion in the cleaning solution
2 editions published in 2007 in French and held by 2 WorldCat member libraries worldwide
Cleaning efficiency and the removal of metallic contaminations have appreciable impact on productivity and reliability. The control of metallic residuals is essential with the implementation of new integration schemes such as self aligned barrier. This study de,.als with the use of two derivative AFM techniques for the characterization of post-CMP and post-CMP cleaned surfaces: the c-AFM for the measurement of surface leakage and the KFM for the measurement of surface potentials and work functions. The first part highlights that the Ta/TaN polishing time has a crucial impact on the surface leakage. The issues observed during the measurements with our experimental conditions will be discussed. KFM analyses show the impact of CMP and post-CMP clean parameters on surface potentials. Work function measurements on post-CMP copper samples show the influence of the passivation layer. The copper work function is reduced, depending on the nature of the passivation layer formed during the immersion in the cleaning solution
Modification de surface et caractérisation électrochimique d'électrodes de diamant dopé bore by
Paolo Actis(
Book
)
2 editions published in 2008 in French and held by 2 WorldCat member libraries worldwide
Excellent mechanical properties, high chemical inertness and biocompatibility have made boron doped diamond electrodes (BDD) a promising material for applications in the biomedical field. Amine-terminated BDD interfaces were obtained through solvent free chemical grafting of diazonium salts on hydrogen terminated BDD electrodes. Next to X-ray photoelectron spectroscopy (XPS) and cyc1ic voltammetry, the presence and electrochemical behaviour of the linked functional groups were identified using Raman spectroscopy. ln parallel, the influence of the presence of amine groups on the electronic transfer kinetics and the possibility to deposit go Id nanopartic1es was studied. Photochemical oxidized BDD allowed furthermore the linking of photoactive benzophenone molecules and the photoimmobilization of oligonuc1eotide (DNA) strands. Finally, the potential of scanning probe techniques such as scanning electrochemical microscopy (SECM) and electrochemical scanning near field optical microscopy (E-SNOM) to locally pattern BDD electrodes was demonstrated
2 editions published in 2008 in French and held by 2 WorldCat member libraries worldwide
Excellent mechanical properties, high chemical inertness and biocompatibility have made boron doped diamond electrodes (BDD) a promising material for applications in the biomedical field. Amine-terminated BDD interfaces were obtained through solvent free chemical grafting of diazonium salts on hydrogen terminated BDD electrodes. Next to X-ray photoelectron spectroscopy (XPS) and cyc1ic voltammetry, the presence and electrochemical behaviour of the linked functional groups were identified using Raman spectroscopy. ln parallel, the influence of the presence of amine groups on the electronic transfer kinetics and the possibility to deposit go Id nanopartic1es was studied. Photochemical oxidized BDD allowed furthermore the linking of photoactive benzophenone molecules and the photoimmobilization of oligonuc1eotide (DNA) strands. Finally, the potential of scanning probe techniques such as scanning electrochemical microscopy (SECM) and electrochemical scanning near field optical microscopy (E-SNOM) to locally pattern BDD electrodes was demonstrated
Développement de nouvelles interfaces plasmoniques appliquées à la biodétection by
Maël Manesse(
Book
)
2 editions published in 2009 in French and held by 2 WorldCat member libraries worldwide
L'utilisation de techniques de détection sans marquage telles que les méthodes basées sur la résonance de plasmons de surface (SPR) et l'électrochimie représentent un enjeu très important dans le développement des capteurs miniaturisés. Dans ce travail de thèse, de nouvelles interfaces adaptées aux études SPR-électrochimique ont été développées. Ces interfaces sont formées en déposant un film mince d'oxyde sur des substrats Titane/Or (Ti/Au) classiquement utilisés en SPR. Différents types d'interfaces hybrides ont été développées, comme Ti/Au/SiOx (oxyde de silicium), Ti/Au/SnO2:Sb (oxyde d'étain dopé antimoine) et Ti/Ag/SnO2:Sb. La caractérisation de ces nouvelles couches a été menée par électrochimie, résonance de plasmons de surface et spectroscopie de photoélectrons X (XPS). Différentes étapes de chimie de surface ont été étudiées sur ces interfaces afin de montrer la possibilité de greffer de manière covalente des biomolécules comme l'ADN sur le film d'oxyde
2 editions published in 2009 in French and held by 2 WorldCat member libraries worldwide
L'utilisation de techniques de détection sans marquage telles que les méthodes basées sur la résonance de plasmons de surface (SPR) et l'électrochimie représentent un enjeu très important dans le développement des capteurs miniaturisés. Dans ce travail de thèse, de nouvelles interfaces adaptées aux études SPR-électrochimique ont été développées. Ces interfaces sont formées en déposant un film mince d'oxyde sur des substrats Titane/Or (Ti/Au) classiquement utilisés en SPR. Différents types d'interfaces hybrides ont été développées, comme Ti/Au/SiOx (oxyde de silicium), Ti/Au/SnO2:Sb (oxyde d'étain dopé antimoine) et Ti/Ag/SnO2:Sb. La caractérisation de ces nouvelles couches a été menée par électrochimie, résonance de plasmons de surface et spectroscopie de photoélectrons X (XPS). Différentes étapes de chimie de surface ont été étudiées sur ces interfaces afin de montrer la possibilité de greffer de manière covalente des biomolécules comme l'ADN sur le film d'oxyde
Graphene-modified electrodes for sensing doxorubicin hydrochloride in human plasma by Fereshteh Chekin(
)
1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide
1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide
Toxicity effect of graphene oxide on growth and photosynthetic pigment of the marine alga Picochlorum sp. during different
growth stages by Layla J Hazeem(
)
1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide
1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide
Different strategies for functionalization of diamond surfaces by
Sabine Szunerits(
)
1 edition published in 2007 in English and held by 2 WorldCat member libraries worldwide
1 edition published in 2007 in English and held by 2 WorldCat member libraries worldwide
Dopamine-functionalized cyclodextrins: modification of reduced graphene oxide based electrodes and sensing of folic acid in
human serum by Fereshteh Chekin(
)
1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide
1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide
Comportement électrochimique et tribo-électrochimique de l'alliage CoCrMo en milieu physiologique simulé : influence des
protéines by
Aziz Ouerd(
Book
)
2 editions published in 2009 in French and held by 2 WorldCat member libraries worldwide
The formation of a thin passive oxide film consisting of a mixture of chromium, cobalt and molybdenum oxides, confers to CoCrMo alloys a good corrosion resistance in physiological medium. Unfortunately, this extremely thin film is susceptible to fracture under mechanical loading, resulting in exposure of the alloy to this medium. Subsequent electrochemical processes dissolve the alloy. Metal ions are released into the surrounding tissues causing inflammations. The aim of the present work is to understand the effect of surface modification of CoCrMo alloys, in the presence of phosphates and proteins, on their corrosion. Its effects on tribocorrosion is detailed in a second part
2 editions published in 2009 in French and held by 2 WorldCat member libraries worldwide
The formation of a thin passive oxide film consisting of a mixture of chromium, cobalt and molybdenum oxides, confers to CoCrMo alloys a good corrosion resistance in physiological medium. Unfortunately, this extremely thin film is susceptible to fracture under mechanical loading, resulting in exposure of the alloy to this medium. Subsequent electrochemical processes dissolve the alloy. Metal ions are released into the surrounding tissues causing inflammations. The aim of the present work is to understand the effect of surface modification of CoCrMo alloys, in the presence of phosphates and proteins, on their corrosion. Its effects on tribocorrosion is detailed in a second part
Microscopie électrochimique pour l'élaboration et la caractérisation de bio-assemblages sur électrode : application aux
biopuces by
Elodie Fortin(
Book
)
2 editions published in 2005 in French and held by 2 WorldCat member libraries worldwide
This work deals with : (i) the electrochemical detection of nucleosides on a new carbon electrode material, Boron Doped Diamond (BDD), and (ii) the use of a recent apparatus, scanning electrochemical microscopy (SECM) to micropattern surfaces with oligonucleotides and to detect the hybridization event. On the one hand, we illustrate the capacity of scanning electrochemical microscopy to micropattern and characterize surfaces. By direct mode of SECM, using the microelectrode as a counter electrode, polypyrrole-oligonucleotide spots with micrometric dimensions are deposited on a gold surface. This patterning method is optimized studying the spots hybridization by fluorescence microscopy. By the difference in surface conductivity between gold and polypyrrole-oligonucleotide, SECM can detect the spots on the gold surface using the feedback mode. Then, the hybridization event is detected using the feedback mode by the precipitation of an insulating product on the surface generated by the reaction catalysed by the peroxidase which is coupled by a biological assembly to the complementary oligonucleotide. Finally, this electrochemical method is coupled to an optical one, Surface Plasmon Resonance imaging (SPRi), to visualize in real time the patterning step of the gold surface with oligonucleotide spots or surface oligonucleotide gradients. On the other hand, the oxidation reactions of both nucleosides, 2'-deoxyguanosine and 2'-deoxyadenosine, are performed on an oxygenated boron doped diamond electrode. This points out the interest of this new material thanks to its enlarged potential window in aqueous media and its little and stable background current. Then, we show the formation of a continuous film of oxidized products on the BDD surface by a macroscopic study analysing cyclic voltametries of a redox mediator, and in a microscopic way with the use of scanning electrochemical microscopy
2 editions published in 2005 in French and held by 2 WorldCat member libraries worldwide
This work deals with : (i) the electrochemical detection of nucleosides on a new carbon electrode material, Boron Doped Diamond (BDD), and (ii) the use of a recent apparatus, scanning electrochemical microscopy (SECM) to micropattern surfaces with oligonucleotides and to detect the hybridization event. On the one hand, we illustrate the capacity of scanning electrochemical microscopy to micropattern and characterize surfaces. By direct mode of SECM, using the microelectrode as a counter electrode, polypyrrole-oligonucleotide spots with micrometric dimensions are deposited on a gold surface. This patterning method is optimized studying the spots hybridization by fluorescence microscopy. By the difference in surface conductivity between gold and polypyrrole-oligonucleotide, SECM can detect the spots on the gold surface using the feedback mode. Then, the hybridization event is detected using the feedback mode by the precipitation of an insulating product on the surface generated by the reaction catalysed by the peroxidase which is coupled by a biological assembly to the complementary oligonucleotide. Finally, this electrochemical method is coupled to an optical one, Surface Plasmon Resonance imaging (SPRi), to visualize in real time the patterning step of the gold surface with oligonucleotide spots or surface oligonucleotide gradients. On the other hand, the oxidation reactions of both nucleosides, 2'-deoxyguanosine and 2'-deoxyadenosine, are performed on an oxygenated boron doped diamond electrode. This points out the interest of this new material thanks to its enlarged potential window in aqueous media and its little and stable background current. Then, we show the formation of a continuous film of oxidized products on the BDD surface by a macroscopic study analysing cyclic voltametries of a redox mediator, and in a microscopic way with the use of scanning electrochemical microscopy
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- Boukherroub, Rabah Other Opponent Thesis advisor Author Editor
- Zhu, Jun-Jie Other Editor
- Downard, Alison Other Editor
- Yang, Nianjun Author Editor
- Drider, Djamel Other Editor
- Peteu, Serban Author Editor
- Bayachou, Mekki Author Editor
- Royal Society of Chemistry (Great Britain)
- Knoll, Wolfgang
- Vasilescu, Alina
Useful Links
Associated Subjects
Antibiotics Biosensors Coronavirus infections--Diagnosis Coronavirus infections--Treatment Coronavirus infections--Vaccination COVID-19 (Disease)--Research Drug delivery systems Drug resistance in microorganisms Electrochemical analysis Electrodes, Carbon Nanomedicine Nanostructured materials--Electric properties Peroxynitrite Physics Plasmons (Physics) Skin absorption Surface plasmon resonance Transdermal medication