WorldCat Identities

Moura, Patricia

Overview
Works: 6 works in 6 publications in 2 languages and 7 library holdings
Publication Timeline
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Most widely held works by Patricia Moura
Detection of circulant tumor necrosis factor-alpha, soluble tumor necrosis factor p75 and interferon-gamma in Brazilian patients with dengue fever and dengue hemorrhagic fever by Elzinandes L. A Braga( )

1 edition published in 2001 in English and held by 2 WorldCat member libraries worldwide

Pro-inflammatory cytokines are believed to play an important role in the pathogenesis of dengue infection. This study reports cytokine levels in a total of 54 patients examined in Recife, State of Pernambuco, Brazil. Five out of eight patients who had hemorrhagic manifestations presented tumor necrosis factor-alpha (TNF-alpha) levels in sera which were statistically higher than those recorded for controls. In contrast, only one out of 16 patients with mild manifestations had elevated TNF-alpha levels. The levels of interleukin-6 (IL), IL-1beta tested in 24 samples and IL-12 in 30 samples were not significantly increased. Interferon-g was present in 10 out of 30 patients with dengue. The data support the concept that the increased level of TNF-alpha is related to the severity of the disease. Soluble TNF receptor p75 was found in most patients but it is unlikely to be related to severity since it was found with an equivalent frequency and levels in 15 patients with dengue fever and another 15 with dengue hemorrhagic fever (AU)
Third generation biohydrogen production by Clostridium butyricum and adapted mixed cultures from Scenedesmus obliquus microalga biomass( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Highlights: A mixed culture and C. butyricum were used to ferment dried and ground S. obliquus biomass. The best adapted mixed culture LE37 produces 1.52 mol H2 /mol from 50 g/L of dried and ground S. obliquus . C. butyricum produces 116.3 mL H2 /g alga vs, attaining a H2 yield of 2.74 mol/mol. The biogas produced by C. butyricum has the highest purity, H2 /CO2 (v/v) of 1.7. Abstract: Scenedesmus obliquus biomass was used as a feedstock for comparing the biological production of hydrogen by two different types of anaerobic cultures: a heat-treated mixed culture from a wastewater treatment plant and Clostridium butyricum DSM 10702. The influence of the incubation temperature and the carbon source composition were evaluated in order to select the best production profile according to the characteristics of the microalgal biomass. C. butyricum showed a clear preference for monomeric sugars and starch, the latter being the major storage compound in microalgae. The highest H2 production reached by this strain from starch was 468 mL/g, whereas the mixed culture incubated at 37 °C (LE37) produced 241 mL/g. When the mixed culture was incubated at 58 °C (LE58), a significant increase in the H2 production occurred when xylose and xylan were used as carbon and energy source. The highest H2 yield reached by the LE37 culture or in co-culture with C. butyricum was 1.52 and 2.01 mol/mol of glucose equivalents, respectively. However, the ratio H2 /CO2 (v/v) of the biogas produced in both cases was always lower than the one produced by the pure strain. In kinetic assays, C. butyricum attained 153.9 mL H2 /L h from S. obliquus biomass within the first 24 h of incubation, with a H2 yield of 2.74 mol/mol of glucose equivalents. H2 production was accompanied mainly by acetate and butyrate as co-products. In summary, C. butyricum demonstrated a clear supremacy for third generation bioH2 production from S. obliquus biomass
Triagem neonatal para hemoglobinopatias no Rio de Janeiro, Brasil by Clarisse Lopes de Castro Lobo( )

1 edition published in 2003 in Portuguese and held by 1 WorldCat member library worldwide

OBJETIVO: Descrever os principais resultados do programa de triagem neonatal para a doenca falciforme do Estado do Rio de Janeiro em 15 meses de funcionamento (agosto de 2000 a novembro de 2001). METODOS: A partir de agosto de 2000, amostras de sangue passaram a ser coletadas de todos os recem-nascidos atendidos em postos de atencao basica a saude no Estado para triagem neonatal da doenca falciforme. Essas amostras sao submetidas a cromatografia liquida de alta resolucao. Se o cromatograma resultante for compativel com a doenca falciforme, a crianca e seus pais sao encaminhados para confirmacao diagnostica e tratamento. RESULTADOS: De agosto de 2000 a novembro de 2001, 99 260 recem nascidos participaram da triagem. Houve um caso de homozigose para Hb C. Um em cada 27 recem-nascidos triados pelo programa apresentou o traco falciforme (Hb AS). A doenca falciforme foi constatada em 83 casos (um caso novo para cada 1 196 nascimentos): 62 Hb S, 18 Hb SC, 3 Hb SD. Uma crianca nao compareceu para confirmacao diagnostica. As 82 criancas acompanhadas apresentaram 15 intercorrencias (infeccoes de vias aereas superiores, febre, sequestro esplenico, sindrome mao-pe e crises de vaso-oclusao), motivando sete internacoes. Houve necessidade de transfusao sanguinea em 15 criancas, mas nenhuma tornou-se alo-imunizada. Os demais bebes estao evoluindo satisfatoriamente com o uso de penicilina profilatica. CONCLUSOES: Nossos dados evidenciam a importancia do diagnostico precoce da doenca falciforme, de forma a prevenir e evitar as frequentes complicacoes infecciosas enfrentadas por esses pacientes (AU)
Assessment of the adequacy of different Mediterranean waste biomass types for fermentative hydrogen production and the particular advantage of carob (Ceratonia siliqua L.) pulp( )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

Abstract: The conversion of agro-industrial byproducts, residues and microalgae, which are representative or adapted to the Mediterranean climate, to hydrogen (H2 ) by C. butyricum was compared. Five biomass types were selected: brewery's spent grain (BSG), corn cobs (CC), carob pulp (CP), Spirogyra sp. (SP) and wheat straw (WS). The biomasses were delignified and/or saccharified, except for CP which was simply submitted to aqueous extraction, to obtain fermentable solutions with 56.2-168.4g total sugars L −1 . In small-scale comparative assays, the H2 production from SP, WS, CC, BSG and CP reached 37.3, 82.6, 126.5, 175.7 and 215.8mL(g biomass) −1, respectively. The best fermentable substrate (CP) was tested in a pH-controlled batch fermentation. The H2 production rate was 204mL(Lh) −1 and a cumulative value of 3.9L H2 L −1 was achieved, corresponding to a H2 production yield of 70.0mL(g biomass) −1 or 1.6mol(mol of glucose equivalents) −1 . The experimental data were used to foresight a potential energy generation of 2.4 GWh per year in Portugal, from the use of CP as substrate for H2 production. Highlights: Mediterranean waste biomasses are suitable for fermentative H2 production. Sugar-rich carob pulp (CP) extract is obtained by simple water extraction. The fermentation of CP extract by C. butyricum produces 215.8L H2 kgd.w. −1 . The H2 production rate from CP extract in bioreactor is 440mL(Lh) −1 . Through H2 production, CP can potentially generate 2.4 GWh y −1 in Portugal
Genotipo MLB2 materno influencia a transmissao vertical em criancas brasileiras by Sergio Crovella( )

1 edition published in 2004 in Portuguese and held by 1 WorldCat member library worldwide

O presente estudo analisa os polimorfismos geneticos no primeiro exon MBL2, em um coorte de 21 pares de maes e filhos infectados por HIV-1 e um coorte de 11 pares constituidos por maes infectadas por HIV-1 e filhos nao infectados, na cidade de Recife(PE), localizada no nordeste do Brasil, com objetivo de avaliar se o genotipo MBL2, de maes infectadas por HIV-1 poderia estar relacionado com transmissibilidade do virus para seus conceptos. Todas criancas nasceram de maes infectadas por HIV-1 que nao haviam recebido nenhum tratamento antiretroviral durante a gravidez e nao foram submetidas a parto cesareano para prevenir transmissao. Maes que transmitiram HIV-1 a seus conceptos (MT) tinham frequencia mais alta (14 porcento) de genotipo 00 no MBL2(tipico de maus produtores de MBL) se comparado com frequencia de 0 porcento observada entre maes infectadas que transmitiram o virus para seus filhos (MNT). Esta diferenca foi estatisticamente significante. A presenca do genotipo 0 e 00 no alelo MBL2 em MT se associou com transmissao viral. O genotipo AA de MBL (associado com producao normal de MBL) teve frequencia de 82 porcento em MNT, significantemente mais alta que a frequencia de 52 porcento de MT. A presenca do alelo A em 91 porcento das MNT conferiu menor risco de transmissao vertical no coorte estudado. Nossos resultados sugerem que a transmissao vertical de HIV-1 depende somente do genotipo MBL2 da crianca e da mae, nas quais os niveis da proteina MBL poderiam desempenhar um importante papel na transmissao do virus
Project alpha( Book )

1 edition published in 1988 in English and held by 1 WorldCat member library worldwide

 
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