WorldCat Identities

Rossello, Armando

Overview
Works: 80 works in 80 publications in 2 languages and 80 library holdings
Roles: Author
Publication Timeline
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Most widely held works by Armando Rossello
Sintesi ed attività biologica di alcuni nuovi azoli antifungini strutturalmente correlati con l'ossiconazolo : tesi di laurea by Annalisa Montinaro( Book )

1 edition published in 1998 in Italian and held by 1 WorldCat member library worldwide

Sintesi e proprietà adrenergiche di analoghi isossazolinici di eteri e di ossime ß-bloccanti : tesi di laurea by Alessandra Mancini( Book )

1 edition published in 1988 in Italian and held by 1 WorldCat member library worldwide

Derivati tiofenici e benzotiofenici quali potenziali ligandi al recettore delle benzodiazepine : tesi di laurea by Silvia Velo( Book )

1 edition published in 1992 in Italian and held by 1 WorldCat member library worldwide

In Vivo Imaging of Matrix Metalloproteinase 12 and Matrix Metalloproteinase 13 Activities in the Mouse Model of Collagen-Induced Arthritis( )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

Abstract Objective To develop enzyme-activatable Förster resonance energy transfer (FRET) substrate probes to detect matrix metalloproteinase 12 (MMP-12) and MMP-13 activities in vivo in mouse models of inflammatory arthritis. Methods Peptidic FRET probes activated by MMP-12 and MMP-13 were reverse designed from inhibitors selected from a phosphinic peptide inhibitor library. Selectivity of the probes was demonstrated in vitro using MMP-1, MMP-2, MMP-3, MMP-12, and MMP-13. In vivo activation of the probes was tested in the zymosan-induced mouse model of inflammation, and probe specificity was evaluated by the MMP inhibitor GM6001 and specific synthetic inhibitors of MMP-12 and MMP-13. The probes were used to monitor these enzyme activities in the collagen-induced arthritis (CIA) model in vivo. Results The MMP-12 and MMP-13 activity probes (MMP12ap and MMP13ap, respectively) discriminated between the activities of the 2 enzymes. The in vivo activation of these probes was inhibited by GM6001 and by their respective specific inhibitors. In the CIA model, MMP12ap activation peaked 5 days after disease onset and showed strong correlation with disease severity during this time (r = 0.85, P <0.0001). MMP13ap activation increased gradually after disease onset and correlated with disease severity over a longer period of 15 days (r = 0.58, P <0.0001). Conclusion We generated two selective FRET probes that can be used to monitor MMP-12 and MMP-13 activities in live animals. MMP12ap follows the initial stage of inflammation in CIA, while MMP13ap follows the progression of the disease. The specificity of these probes is useful in monitoring the efficacy of MMP inhibitors
Metaboliti secondari da senecio mikanioides otto : aspetti chemiotassonomici e biologici : tesi di laurea by Stefano Luschi( Book )

1 edition published in 1995 in Italian and held by 1 WorldCat member library worldwide

[Pi]-Stacking ed induzione asimmetrica : sintesi ed utilizzo del naftil 3,4,6-tri-0-metil-ss-D glucopiranoside : tesi di laurea by Paola Munforte( Book )

1 edition published in 1996 in Italian and held by 1 WorldCat member library worldwide

Sintesi di acidi 4-aminossi-3-carbossi-2-butenoici quali catene laterali per gli antibiotici ß-lattamici : tesi di laurea by Maria Rosaria Maci( Book )

1 edition published in 1992 in Italian and held by 1 WorldCat member library worldwide

Effetti della Silimarina sulla risposta allo shock anafilattico e sull'iper-reattività bronchiale nella cavia in vivo : tesi di laurea by Salvatore Vitali( Book )

1 edition published in 1998 in Italian and held by 1 WorldCat member library worldwide

Sintesi di acidi 3-aminossi-2- carbonilmetossimmino-propionici quali catene laterali per gli antibiotici ß-lattamici : tesi di laurea by Lisa Nacci( Book )

1 edition published in 1992 in Italian and held by 1 WorldCat member library worldwide

Derivati 4-metil-1.8-naftiridinici a potenziale attività antiipertensiva : tesi di laurea by Silvia Redini( Book )

1 edition published in 1992 in Italian and held by 1 WorldCat member library worldwide

Crystal and molecular structure 0f 2ß-acetoxymethyl-3alfa-methoxy-2alfa-methyl-3ß-(p-nitrobenzoyloxymethyl)-6ß-phenoxyacetamidopenam( Book )

1 edition published in 1987 in English and held by 1 WorldCat member library worldwide

Sintesi di derivati 1,8-naftiridinici a potenziale attività inibitoria delle fosfodiesterasi IV umane : tesi di laurea by Marco Ferrini( Book )

1 edition published in 2001 in Italian and held by 1 WorldCat member library worldwide

Studio della diastereoselettività facciale nelle reazioni di addizione elettrofila a glicali : tesi di laurea by Antonella Boschi( Book )

1 edition published in 1998 in Italian and held by 1 WorldCat member library worldwide

Sintesi ed attività antibatterica di 5,6 - di idrobenzo-carbazoli : tesi di laurea by Antonio Garigali( Book )

1 edition published in 1996 in Italian and held by 1 WorldCat member library worldwide

Studi sulla reattività dei doppi legami di 3-cefem e 3-esometilenecefam derivati : tesi di laurea by Armando Rossello( Book )

1 edition published in 1981 in Italian and held by 1 WorldCat member library worldwide

Sintesi di nuovi eterocicli polinucleari contenenti il nucleo della 8-tioteofillina : tesi di laurea by Luisa Gori( Book )

1 edition published in 1996 in Italian and held by 1 WorldCat member library worldwide

Indagine fitochimica su Astragalis Verrucosus : tesi di laurea by Stefania Pardossi( Book )

1 edition published in 1995 in Italian and held by 1 WorldCat member library worldwide

Sintesi e proprietà inibitrici sulle elastasi umane di derivati 1-carbamoil-4-metilenamminossi azetidinonici : [tesi di laurea] by Cecilia De^Sio( Book )

1 edition published in 1996 in Italian and held by 1 WorldCat member library worldwide

 
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Audience level: 0.98 (from 0.88 for In Vivo Im ... to 0.99 for Sintesi e ...)

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