WorldCat Identities

Vidal Sanz, Manuel

Works: 13 works in 23 publications in 2 languages and 38 library holdings
Roles: Translator, Author
Publication Timeline
Most widely held works by Manuel Vidal Sanz
Eye, brain, and vision by David H Hubel( Book )

4 editions published between 1999 and 2000 in Spanish and held by 18 WorldCat member libraries worldwide

Shows how science is constructing a wiring diagram of the visual path, shows about the structure of receptors in the retina, through the peanut-size clusters of cells known as the lateral geniculate bodies, to the striate cortex-- the first of many higher areas devoted to vision and the part of the brain that is now best understood. Introduces the remarkable geometric patterns that result from the surprising tendency of cells with related functions to be organized in sheets, columns, blobs, and stripes
Regenerative responses of injured adult rat retinal ganglion cells : axonal elongation, synapse formation and persistence of connections by Manuel Vidal-Sanz( )

3 editions published between 1990 and 1992 in English and held by 7 WorldCat member libraries worldwide

"To characterize the regenerative responses of adult mammalian central nervous system (CNS) neurons, their potential for axonal elongation, terminal growth, and synaptogenesis has been investigated in the retino-collicular system of the adult rat. For these studies, an experimental paradigm has been developed in the adult rat which consists of the total substitution of the optic nerve by an autologous segment of peripheral nerve (PN). The PN segment is used to promote axonal growth from axotomized retinal ganglion cells (RGCs) and to direct this growth towards the superior colliculus (SC), which is their main target in the normal CNS. In light and electron microscopic studies, after the application of retrogradely and orthogradely transported tracers and immunocytochemical markers, it has been documented that: (i) Up to 10% of the original RGC population can regenerate axons along these PN segments for distances that surpass those that separate the retina from the SC; (ii) Upon arrival at the interface created by the PN segment and the SC, some of the regenerated retinal axons extend and appear to arborize in the superficial layers of the SC for distances of approximately 500 $ mu$m; (iii) The retinal axons are capable of terminal differentiation and synapse formation in the SC, and; (iv) Re-formed axonal terminals, analyzed 16-18 months after connecting the retina to the SC, are not different from those observed in age-matched controls." --
Estudios electrorretinográficos en modelos de neurodegeneración en el sistema visual del roedor adulto by Luis Alarcón Martínez( )

2 editions published in 2009 in Spanish and held by 1 WorldCat member library worldwide

Regeneración de la corteza somatosensorial de la rata adulta : estudio anatómico : implicaciones electrofisiológicas by Manuel Vidal Sanz( )

2 editions published in 1984 in Spanish and held by 1 WorldCat member library worldwide

Fisiología de la retina by Manuel Vidal Sanz( )

2 editions published in 2012 in Spanish and held by 1 WorldCat member library worldwide

MicroRNA regulation in an animal model of acute ocular hypertension( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation by Per-Henrik D Edqvist( )

1 edition published in 2012 in English and held by 1 WorldCat member library worldwide

Platelet-derived growth factor (PDGF) plays an important role in development of the central nervous system, including the retina. Excessive PDGF signaling is associated with proliferative retinal disorders. We reported previously that transgenic mice in which PDGF-B was over-expressed under control of the nestin enhancer, nes/tk-PdgfB-lacZ, exhibited enhanced apoptosis in the developing corpus striatum. These animals display enlarged lateral ventricles after birth as well as behavioral aberrations as adults. Here, we report that in contrast to the relatively mild central nervous system phenotype, development of the retina is severely disturbed in nes/tk-PdgfB-lacZ mice. In transgenic retinas all nuclear layers were disorganized and photoreceptor segments failed to develop properly. Since astrocyte precursor cells did not populate the retina, retinal vascular progenitors could not form a network of vessels. With time, randomly distributed vessels resembling capillaries formed, but there were no large trunk vessels and the intraocular pressure was reduced. In addition, we observed a delayed regression of the hyaloid vasculature. The prolonged presence of this structure may contribute to the other abnormalities observed in the retina, including the defective lamination
Regeneración axonal de las células ganglionares de la retina de ratones albinos en injerto autólogo de nervio periférico by Laura Patricia Zorrilla Matilla( Book )

1 edition published in 2013 in Spanish and held by 1 WorldCat member library worldwide

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Audience level: 0.65 (from 0.37 for Eye, brain ... to 1.00 for Axonal reg ...)

Eye, brain, and vision