WorldCat Identities

Tourniaire, Franck

Works: 4 works in 5 publications in 2 languages and 7 library holdings
Roles: Author, Other
Publication Timeline
Most widely held works by Franck Tourniaire
Stabilité, transport et métabolisme de microconstituants phénoliques dans le tube digestif by Franck Tourniaire( Book )

2 editions published in 2006 in French and held by 2 WorldCat member libraries worldwide

Polyphenols are the most widely occuring microconstituent family of our diet. Animal studies as well as some epidemiological data show an inverse association between the high intake of some popyphenol classes and the incidence of evolutive diseases such as atherosclerosis and cancer. Biological effects of a molecule depend on its bioavailability, and polyphenol bioavailability remains obscure. In the present work, two determinant aspects of bioavailabilty have been investigated: 1) Stability during gastro-intestinal digestion. In vitro acellular studies have shown that polyphenol stability depends on their molecular structure. Moreover, it has been observed that polyphenols are able to protect other classes of dietary antioxidants (vitamin E and carotenoids) from oxidation in the upper digestive tract. These results could explain the of some supplementation studies. 2) Absorption and metabolism by enterocytes. Absorption studies across differentiated Caco-2/TC7 cells have been performed with two frequently dietary occurring molecules, vanillin and naringin. Data displayed that transport and metabolism mechanisms depend on the structure, and several metabolites have been identified. Weak absorption of naringin and extensive metabolism of vanillin by enterocytes are responsible of the poor intestinal absorption of these compounds. Taken together, these data could contribute to the elucidation of the in vivo biological effects of polyphenols
Multivitamin restriction increases adiposity and disrupts glucose homeostasis in mice by Nisserine Ben Amara( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

<> by Franck Tourniaire( )

1 edition published in 2009 in English and held by 2 WorldCat member libraries worldwide

Audience Level
Audience Level
  General Special  
Audience level: 0.00 (from 0.00 for Multivitam ... to 0.00 for Multivitam ...)