WorldCat Identities

Mérieau, Annabelle

Overview
Works: 8 works in 10 publications in 2 languages and 18 library holdings
Roles: Contributor, Author, Thesis advisor
Classifications: QH331, 570
Publication Timeline
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Most widely held works by Annabelle Mérieau
Étude des facteurs de virulence et de l'implication des phénomènes de variations phénotypiques dans la pathogénie d'une souche hospitalière de Pseudomonas fluorescens MFN1032 by Daniel Spérandio( Book )

2 editions published in 2010 in French and held by 3 WorldCat member libraries worldwide

Pseudomonas fluorescens is a ubiquitous Gram negative bacterium with a high adaptation capacity. Due to its psychrotrophic character, this species is usually considered as nonpathogen. Nevertheless, strains of Pseudomonas fluorescens were identified in hospital in patients suffering from nosocomial diseases. A clinical strain of Pseudomonas fluorescens, MFN1032, was isolated from patient suffering from a lung infection. This strain has a secreted hemolytic activity involving biosurfactants. This strain was subject to phenotypic variation. Two groups of phenotypic variants are defective in biosurfactant production. This suggests biosurfactant production is highly regulated. The phenotypic modification of one variants group results from the disruption of GacA/GacS and could enhance fitness for acute infection. The second group variant may involve a c-di-GMP level variation, which is not yet understood, and shows a phenotype adapted to chronic infection. However, MFN1032 possesses a cell-associated hemolytic activity independent of secreted hemolytic activity, maintained in variants. This activity is thermoregulated and is inhibited by quorum sensing. The GacS/GacA system is a negative regulator of this activity. MFN1032 is virulent towards Dictyostelium discoideum and shows cytotoxicity on macrophage cell line, phenotypes that are independent from biosurfactants. The interruption of an operon containing hrcRST genes, homologous to hrpU operon genes of type three secretion system (T3SS) of Pseudomonas rhizospheric bacteria, provokes the loss of these activities. These results report, for the first time the involvement of T3SS basal part in Pseudomonas fluorescens virulence
Etude des effets de la température de croissance sur la production d'activité lipolytique par l'espèce Pseudomonas fluorescens by Annabelle Merieau( )

2 editions published in 1994 in French and held by 3 WorldCat member libraries worldwide

La production d'activité lipolytique chez P. fluorescens est induite par la composition du milieu et la phase stationnaire de croissance et varie en fonction de la température de croissance. La lipase est produite de façon optimale pour une température de croissance de 17,5°C, température inférieure à la température optimale de croissance (28°C-30°C). Le gène Lip est régulé au niveau transcriptionnel par la température de croissance et la composition du milieu. Le Tween 80 est un inducteur véritable. Il existe des régulations post-transcriptionnelles liées à la température de croissance et à la composition du milieu, la régulation par la phase de croissance n'agit qu'à ce niveau. Il existe des gènes de régulation positive pouvant agir au niveau de la transcription du gène Lip et un gène de régulation négative, agissant à un niveau post-transcriptionnel. Ces gènes sont eux mêmes régulés, soit par la composition du milieu, soit par la phase de croissance, mais tous sont régulés par la température. L'analyse des séquences amont du gène Lip a révélé qu'il existe une structure promotrice du type - « 12-24 » en amont du gène Lip homologue à séquence reconnue par un facteur de type sigma 60. Une séquence homologue avec l'UAS de xyl S a pu être décelée sans qu'une séquence rappelant le IHF n'ait pu être reconnue. L'existence de telles homologies, même non encore expliquées, permet de conforter l'hypothèse de régulateurs transcriptionnels positifs
Cell-associated hemolysis activity in the clinical strain of Pseudomonas fluorescens MFN1032 by Daniel Sperandio( )

1 edition published in 2010 in English and held by 2 WorldCat member libraries worldwide

Virulence of the Pseudomonas fluorescens clinical strain MFN1032 towards Dictyostelium discoideumand macrophages in relation with type III secretion system by Daniel Sperandio( )

1 edition published in 2012 in English and held by 2 WorldCat member libraries worldwide

Epigenetic acquisition of inducibility of type III cytotoxicity in P. aeruginosa by Didier Filopon( )

1 edition published in 2006 in English and held by 2 WorldCat member libraries worldwide

Epigenesis and Dynamic Similarity in Two Regulatory Networks in Pseudomonas Aeruginosa by Janine Guespin-Michel( )

1 edition published in 2004 in English and held by 2 WorldCat member libraries worldwide

A Pseudomonas fluorescens type 6 secretion system is related to mucoidy, motility and bacterial competition by Victorien Decoin( )

1 edition published in 2015 in English and held by 2 WorldCat member libraries worldwide

Involvement of a phospholipase C in the hemolytic activity of a clinical strain of Pseudomonas fluorescens by Gaelle Rossignol( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

 
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Alternative Names
Annabelle Merieau wetenschapper

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