WorldCat Identities

Doll, Martin (1995-....).

Works: 1 works in 1 publications in 1 language and 1 library holdings
Roles: Author
Publication Timeline
Most widely held works by Martin Doll
Conception et synthèse d'azacryptophanes. Influence des atomes d'azote sur les propriétés d'encapsulation du xénon by Martin Doll( )

1 edition published in 2021 in French and held by 1 WorldCat member library worldwide

Within supramolecular chemistry, host-guest chemistry aims the development of hollow molecules able to encapsulate specifically smaller substrates. Applications are ranging from detection or trapping of molecules to catalysis in confined space. Cryptophanes are a family of cage-shaped molecules containing a hydrophobic cavity able to encapsulate several interesting substrates. Thus, they are studied for the formation of MRI-bioprobes, as they can encapsulate xenon as well as for the trapping of toxic heavy metal cations, which are complexed with huge affinity. The modulation of cryptophanes encapsulation properties is generally performed by changing their cavity size, but the introduction of heteroelements in their structure remains almost unstudied, as it requires some synthetic adaptations. The work carried out in this thesis focuses on the design of new nitrogen-containing cryptophanes called tri-azacryptophanes. The synthesis of two generations of tri-azacryptophanes containing aniline groups is reported, along with their properties of xenon recognition in organic medium. They encapsulate xenon with drastically different properties than their fully oxygenated analogs. Moreover, these properties vary under pH changes, thanks to the protonation of the aniline groups. Finally, the synthesis of an amphoteric tri-azacryptophane is reported. This compound shows first encouraging results for the encapsulation of xenon in water, which is an interesting step toward applications as an MRI-bioprobe, and the presence of nitrogen atoms seems also to increase the affinity for heavy metal cations in basic water
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French (1)