WorldCat Identities

Sayegh, Johnny

Overview
Works: 3 works in 5 publications in 2 languages and 7 library holdings
Roles: Opponent, Author
Publication Timeline
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Most widely held works by Johnny Sayegh
Traitement d'induction chez le patient transplanté rénal immunisé sans DSA pré-greffe by Annabelle Goumard( )

2 editions published in 2018 in French and held by 3 WorldCat member libraries worldwide

Background. Basiliximab induction was reserved to unimmunized patients. However, the improvement of immunological risk determination led to its utilisation for immunised patients without donor specific antibodies (DSA). The objective was to study the efficiency of basiliximab in immunized kidney transplanted recipients (KTR) without DSA. Methods. Monocentric retrospective study included all adults renal transplant recipient since single antigen bead (SAB) assay introduction in 2007 June until 2017 June. DSA absence detected by SAB has been validated after each folder analysis. Univariate and multivariate analysis of biopsy proven acute rejection (BPAR) risk and DSA appearance has been done. Results. 218 (21%) immunized kidney transplant recipients without pre-graft DSA were identified (basiliximab=60; rATG=158). Patients treated with basiliximab had a lower cPRA (24±26 vs, 66±32, p <0.0001), were more likely to receive a first graft (88 vs 63%, p <0,0001) or a transplant with a living donor (13% vs 2%, p= 0.005). During the mean follow up of 4 years, BPAR risk was higher in basiliximab group (n=15, 25%) than in rATG group (n=13, 8.2%) (p=0.0009). This increased risk remained after adjustment for models different. The occurrence of DSA (MFI> 1000) was observed in 13 (21.7%) and 25 (15.8%) patients treated with basiliximab and rATG respectively (p = 0.167). Moreover, no difference side effects have been noticed between the 2 groups. Conclusions. These results suggest that the use of rATG should be preferable in the prevention of BPAR in immunized KTR without pre-grafts DSA
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2 editions published in 2016 in English and held by 2 WorldCat member libraries worldwide

Fatal case of perforated appendicitis in an elderly CAPD patient by Johnny Sayegh( )

1 edition published in 2011 in English and held by 2 WorldCat member libraries worldwide

 
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Audience level: 0.93 (from 0.88 for <> ... to 0.97 for Traitement ...)

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