WorldCat Identities

Gouw, Samantha C.

Overview
Works: 6 works in 6 publications in 1 language and 10 library holdings
Roles: Contributor
Publication Timeline
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Most widely held works by Samantha C Gouw
Preventing or Eradicating Factor VIII Antibody Formation in Patients with Hemophilia A: What Can We Learn from Other Disorders?( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Patient Perspectives on Novel Treatments in Haemophilia: A Qualitative Study by Erna C. van Balen( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Identifying Nongenetic Risk Factors for Inhibitor Development in Severe Hemophilia A( )

1 edition published in 2013 in English and held by 2 WorldCat member libraries worldwide

The Multifactorial Etiology of Inhibitor Development in Hemophilia: Genetics and Environment( )

1 edition published in 2010 in English and held by 2 WorldCat member libraries worldwide

Measuring activities and participation in persons with haemophilia: A systematic review of commonly used instruments( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Abstract : Introduction: Monitoring clinical outcome in persons with haemophilia (PWH) is essential in order to provide optimal treatment for individual patients and compare effectiveness of treatment strategies. Experience with measurement of activities and participation in haemophilia is limited and consensus on preferred tools is lacking. Aim: The aim of this study was to give a comprehensive overview of the measurement properties of a selection of commonly used tools developed to assess activities and participation in PWH. Methods: Electronic databases were searched for articles that reported on reliability, validity or responsiveness of predetermined measurement tools (5 self-reported and 4 performance based measurement tools). Methodological quality of the studies was assessed according to the COSMIN checklist. Best evidence synthesis was used to summarize evidence on the measurement properties. Results: The search resulted in 3453 unique hits. Forty-two articles were included. The self-reported Haemophilia Acitivity List (HAL), Pediatric HAL (PedHAL) and the performance based Functional Independence Score in Haemophilia (FISH) were studied most extensively. Methodological quality of the studies was limited. Measurement error, cross-cultural validity and responsiveness have been insufficiently evaluated. Conclusion: Albeit based on limited evidence, the measurement properties of the PedHAL, HAL and FISH are currently considered most satisfactory. Further research needs to focus on measurement error, responsiveness, interpretability and cross-cultural validity of the self-reported tools and validity of performance based tools which are able to assess limitations in sports and leisure activities
Vaccinations are not associated with inhibitor development in boys with severe haemophilia A( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Abstract : Background: Inhibitor development in previously untreated patients (PUPs) with severe haemophilia A is a multifactorial event. It is unknown whether paediatric vaccinations given in close proximity to factor VIII (FVIII) are associated with inhibitor development. Objective: To assess whether paediatric vaccinations in close proximity to FVIII within the first 75 exposure days (EDs) are associated with inhibitor development in PUPs with severe haemophilia A. Methods: We included 375 PUPs with severe haemophilia A (<0.01IU/mL) from the PedNet Registry who had received vaccinations between the first and 75th ED or inhibitor development. Inhibitor risk was compared between patients who did and who did not receive vaccinations within 24, 72 or 120hours of FVIII infusion. Unadjusted and adjusted hazard ratios were calculated for any or repeated vaccinations in close proximity to FVIII, using Cox regression. Results: Inhibitor development occurred in 77 of 375 patients (20.5%). Overall inhibitor development appeared similar or lower in patients receiving vaccinations in close proximity to FVIII as compared to patients receiving vaccinations without FVIII: for 24hours, this was 19.2% and 21.4% (P =.186), for 72 hours, 16.4% and 27.3% (P =.023) and for 120hours, 18.3% and 25.0% (P =.085), respectively. Conclusion: We found no association between vaccinations given in close proximity to FVIII exposure within the first 75 EDs and inhibitor development. Our data do not support avoiding administration of FVIII at time of routine vaccinations
 
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Audience level: 0.95 (from 0.88 for The Multif ... to 0.97 for The Multif ...)

Alternative Names
Gouw, S.C. 1978-

Gouw, Samantha C. 1978-

Gouw, Samantha Claudia

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