Persichini, Romain

Precision of the transpulmonary thermodilution measurements by Xavier Monnet( )

1 edition published in 2011 in English and held by 2 WorldCat member libraries worldwide

Observation scales to suspect dyspnea in non-communicative intensive care unit patients by Alexandre Demoule( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

Effets de la noradrénaline sur le retour veineux systémique et la pression systémique moyenne by Romain Persichini( Book )

in French and held by 2 WorldCat member libraries worldwide

Impact of levosimendan on weaning from peripheral venoarterial extracorporeal membrane oxygenation in intensive care unit by Shamir Vally( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Management of Myocardial Dysfunction in Severe Sepsis( )

1 edition published in 2011 in English and held by 2 WorldCat member libraries worldwide

Diagnostic Accuracy of Respiratory Distress Observation Scales as Surrogates of Dyspnea Self-report in Intensive Care Unit Patients( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Abstract : Background: Dyspnea, like pain, can cause major suffering in intensive care unit (ICU) patients. Its evaluation relies on self-report; hence, the risk of being overlooked when verbal communication is impaired. Observation scales incorporating respiratory and behavioral signs (respiratory distress observation scales [RDOS]) can provide surrogates of dyspnea self-report in similar clinical contexts (palliative care). Methods: The authors prospectively studied (single center, 16-bed ICU, large university hospital) 220 communicating ICU patients (derivation cohort, 120 patients; separate validation cohort, 100 patients). Dyspnea was assessed by dyspnea visual analog scale (D-VAS) and RDOS calculated from its eight components (heart rate, respiratory rate, nonpurposeful movements, neck muscle use during inspiration, abdominal paradox, end-expiratory grunting, nasal flaring, and facial expression of fear). An iterative principal component analysis and partial least square regression process aimed at identifying an optimized D-VAS correlate (intensive care RDOS [IC-RDOS]). Results: In the derivation cohort, RDOS significantly correlated with D-VAS (r = 0.43; 95% CI, 0.29 to 0.58). A five-item IC-RDOS (heart rate, neck muscle use during inspiration, abdominal paradox, facial expression of fear, and supplemental oxygen) significantly better correlated with D-VAS (r = 0.61; 95% CI, 0.50 to 0.72). The median area under the receiver operating curve of IC-RDOS to predict D-VAS was 0.83 (interquartile range, 0.81 to 0.84). An IC-RDOS of 2.4 predicted D-VAS of 4 or greater with equal sensitivity and specificity (72%); an IC-RDOS of 6.3 predicted D-VAS of 4 or greater with 100% specificity. Similar results were found in the validation cohort. Conclusions: Combinations of observable signs correlate with dyspnea in communicating ICU patients. Future studies in noncommunicating patients will be needed to determine the responsiveness to therapeutic interventions and clinical usefulness. Abstract : In 220 intensive care unit patients able to communicate, an observational scale containing five nonverbal signs was derived and validated respective to dyspnea self-report. This should help better understand and manage mechanically ventilated patients in the future. Supplemental Digital Content is available in the text

Exacerbation sévère d'asthme nécessitant la ventilation mécanique invasive à l'ère des techniques modernes de réanimation : une étude rétrospective bicentrique by Antoine Binachon( )

1 edition published in 2021 in French and held by 1 WorldCat member library worldwide

Patients with acute severe asthma (ASA) may in rare cases require invasive mechanical ventilation (IMV). However, recent data on this issue are lacking. In this retrospective and bicentric study conducted on a 10 year period, we investigate the in-hospital mortality in patients withASArequiring IMV. We compare this mortality to that of patients with other types of respiratory distress using a standardized mortality ratio (SMR) model. Nowadays, the mortality of patients with ASA requiring IMV is low. Death is due to multi-organ failure, with cardiac arrest on day of admission being the most important risk factor. In patients who did not have cardiac arrest on day of admission the mortality is even lower (4%) which allows an aggressive management