WorldCat Identities

Cachot, Jérôme

Overview
Works: 47 works in 48 publications in 2 languages and 69 library holdings
Roles: Other, Opponent, Thesis advisor, Contributor, Author, Publishing director
Publication Timeline
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Most widely held works by Jérôme Cachot
CARACTERISATION ET ANALYSE DE LA MUTAGENESE DU GENE SUPPRESSEUR DE TUMEUR P53 CHEZ LE FLET, PLATICHTHYS FLESUS (L.) by Jérôme Cachot( Book )

2 editions published in 1998 in French and held by 3 WorldCat member libraries worldwide

UNE ETUDE EPIDEMIOLOGIQUE PRELIMINAIRE REALISEE EN ESTUAIRE ET BAIE DE SEINE A REVELE QUE 1,4% DES FLETS ADULTES PRESENTENT DES ADENOMES HEPATIQUES ET 3,7% DES LESIONS POTENTIELLEMENT PRETUMORALES. DANS LE BUT DE REALISER ULTERIEUREMENT DES ETUDES D'EPIDEMIOLOGIE MOLECULAIRE DU CANCER, LE GENE SUPPRESSEUR DE TUMEUR P53 A ETE ISOLE CHEZ LE FLET PAR CRIBLAGE D'UNE BANQUE D'ADNC. CE GENE CODE POUR UNE PROTEINE DE 366 ACIDES AMINES QUI PRESENTE LES PRINCIPALES CARACTERISTIQUES D'UNE PROTEINE P53, MAIS DONT LES EXTREMITES AMINO ET CARBOXY-TERMINALES ONT NETTEMENT DIVERGEES AU COURS DE L'EVOLUTION. LA STRUCTURE SECONDAIRE ET LES ACIDES AMINES QUI EXERCENT UN ROLE CLE DANS L'ACTIVITE TRANSCRIPTIONNELLE, LA FIXATION SPECIFIQUE A L'ADN ET L'OLIGOMERISATION SONT CONSERVES AU NIVEAU DE LA PROTEINE DE FLET. UN ANTICORPS POLYCLONAL DIRIGE CONTRE UNE PROTEINE P53 RECOMBINANTE DE FLET A ETE PRODUIT AFIN D'ETUDIER LES FONCTIONS DE CETTE PROTEINE ET SON EXPRESSION AU COURS DU PROCESSUS DE TUMORIGENESE. CET ANTICORPS RECONNAIT LA P53 DE FLET ET CELLE DE XENOPE EN WESTERN BLOT MAIS PAS LA PROTEINE HUMAINE. LES MUTATIONS DU GENE P53 ONT ETE ANALYSEES DANS 17 ADENOMES ET LESIONS PRENEOPLASIQUES HEPATIQUES COLLECTEES EN BAIE DE SEINE, EN MER DU NORD ET EN MER BALTIQUE. L'ADN EXTRAIT A ETE AMPLIFIE PAR PCR PUIS SEQUENCE. UNE MUTATION AU NIVEAU DE DEUX FOYERS BASOPHILES AINSI QUE 15 POLYMORPHISMES ONT ETE IDENTIFIES. CETTE MUTATION ENTRAINE UNE SUBSTITUTION D'UNE VALINE PAR UN ACIDE GLUTAMIQUE AU NIVEAU DU CODON 147. LE RESIDU CORRESPONDANT DANS LA P53 HUMAINE EST IMPLIQUE DANS LA SURFACE DE CONTACT A L'ADN. CES RESULTATS SUGGERENT (I) QUE LES PROPRIETES DE LA PROTEINE P53 POURRAIENT ETRE CONSERVEES AU COURS DE L'EVOLUTION ET (II) QUE LE GENE P53 POURRAIT ETRE INACTIVE PAR MUTATION PONCTUELLE AU COURS DU PROCESSUS DE CANCEROGENESE HEPATIQUE CHEZ LE FLET
PAHs and fish--exposure monitoring and adverse effects--from molecular to individual level by Xavier Cousin( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

Oxythermal window drastically constraints the survival and development of European sturgeon early life phases by Nicolas Delage( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Psychotropic drugs in mixture alter swimming behaviour of Japanese medaka (Oryzias latipes) larvae above environmental concentrations by Axelle Chiffre( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

Correction to: From legacy pollutants to emerging contaminants: recent inputs from the 2018 conference of EcoBIM network by Michel Auffret( )

1 edition published in 2020 in English and held by 2 WorldCat member libraries worldwide

Development of a reference artificial sediment for chemical testing adapted to the MELA sediment contact assay by Florane Le Bihanic( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

Juvenile fish caging as a tool for assessing microplastics contamination in estuarine fish nursery grounds by Maria Kazour( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Developmental toxicity of PAH mixtures in fish early life stages. Part II: adverse effects in Japanese medaka by Florane Le Bihanic( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

Influence of sediment composition on PAH toxicity using zebrafish (Danio rerio) and Japanese medaka (Oryzias latipes) embryo-larval assays by Prescilla Perrichon( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

ǂAn ǂinnovative and integrative assay for toxicity testing using individual fish embryos. Application to oxazepam( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

Developmental toxicity of PAH mixtures in fish early life stages. Part I: adverse effects in rainbow trout by Florane Le Bihanic( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

An environmentally realistic pesticide and copper mixture impacts embryonic development and DNA integrity of the Pacific oyster, Crassostrea gigas by Mai Hương( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Seasonal variations of contamination and exoskeletal malformations in the white shrimps Palaemon longirostris in the Gironde estuary, France by Bérenger Levesque( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Molecular and phenotypic responses of Japanese medaka (Oryzias latipes) early life stages to environmental concentrations of cadmium in sediment by Iris Barjhoux( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Health indicators and contaminant levels of a critically endangered species in the Gironde estuary, the European sturgeon by Marie-Laure Acolas( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Application of a multidisciplinary and integrative weight-of-evidence approach to a 1-year monitoring survey of the Seine River by Iris Barjhoux( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Assessment of swimming behavior of the Pacific oyster D-larvae (Crassostrea gigas) following exposure to model pollutants by Perrine Gamain( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Responses of juvenile European flounder (Platichthys flesus) to multistress in the Vilaine estuary, during a 6-month survey by Estérine Evrard( )

1 edition published in 2012 in English and held by 2 WorldCat member libraries worldwide

Evaluation of psychiatric hospital wastewater toxicity: what is its impact on aquatic organisms? by Jean-Yves Mazzitelli( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

 
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Audience Level
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Audience level: 0.96 (from 0.86 for CARACTERIS ... to 0.97 for CARACTERIS ...)

Languages
English (19)

French (2)