WorldCat Identities

École doctorale Galilée (Villetaneuse, Seine-Saint-Denis)

Works: 264 works in 399 publications in 2 languages and 494 library holdings
Roles: Other, 996
Publication Timeline
Most widely held works by Seine-Saint-Denis) École doctorale Galilée (Villetaneuse
Modèles de mélanges topologiques pour la classification de données structurées en séquences by Rakia Jaziri( )

4 editions published in 2013 in French and held by 7 WorldCat member libraries worldwide

Recent years have seen the development of data mining techniques in various application areas, with the purpose of analyzing sequential, large and complex data. In this work, the problem of clustering, visualization and structuring data is tackled by a three-stage proposal. The first proposal present a generative approach to learn a new probabilistic Self-Organizing Map (PrSOMS) for non independent and non identically distributed data sets. Our model defines a low dimensional manifold allowing friendly visualizations. To yield the topology preserving maps, our model exhibits the SOM like learning behavior with the advantages of probabilistic models. This new paradigm uses HMM (Hidden Markov Models) formalism and introduces relationships between the states. This allows us to take advantage of all the known classical views associated to topographic map. The second proposal concerns a hierarchical extension of the approach PrSOMS. This approach deals the complex aspect of the data in the classification process. We find that the resulting model ”H-PrSOMS” provides a good interpretability of classes built. The third proposal concerns an alternative approach statistical topological MGTM-TT, which is based on the same paradigm than HMM. It is a generative topographic modeling observation density mixtures, which is similar to a hierarchical extension of time GTM model. These proposals have then been applied to test data and real data from the INA (National Audiovisual Institute). This work is to provide a first step, a finer classification of audiovisual broadcast segments. In a second step, we sought to define a typology of the chaining of segments (multiple scattering of the same program, one of two inter-program) to provide statistically the characteristics of broadcast segments. The overall framework provides a tool for the classification and structuring of audiovisual programs
Denoising and super-resolution for medical images by example-based learning approach by Dinh Hoan Trinh( Book )

4 editions published in 2013 in English and held by 7 WorldCat member libraries worldwide

L'objectif de cette thèse est d'élaborer des méthodes efficaces pour le débruitage et la super-résolution afin d'améliorer la qualité et la résolution spatiale des images médicales. En particulier, nous sommes motivés par le challenge d'intégrer le problème de débruitage et de super-résolution dans la même formulation. Nos méthodes utilisent des images standards ou d'exemples localisées à proximité de l'image considérée pour le débruitage et/ou pour la super-résolution. Pour le problème de débruitage, nous introduisons trois nouvelles méthodes qui permettent de réduire certains bruits couramment trouvés sur les images médicales. La première méthode est construite sur la base de la Régression Rigide à noyau. Cette méthode peut être appliquée au bruit Gaussien et au bruit Ricien. Pour la deuxième méthode, le débruitage est effectué par le modèle de régression construit sur les K-plus proches voisins. Cette méthode peut être utilisée pour réduire le bruit Gaussien et le bruit Poisson. Nous proposons dans la troisième méthode, un modèle de représentation parcimonieuse pour éliminer le bruit Gaussian sur des images CT à faible dose. Les méthodes de débruitage proposées sont compétitives avec les approches existantes. Pour la super-résolution, nous proposons deux nouvelles méthodes mono-image basées d'exemples. La première méthode est une méthode géométrique par projection sur l'enveloppe convexe. Pour la deuxième méthode, la super-résolution est effectuée via un modèle de représentation parcimonieuse. Les résultats expérimentaux obtenus montrent que les méthodes proposées sont très efficaces pour les images médicales qui sont souvent affectées par les bruits
Diode électroluminescente organique en microcavité verticale à miroirs diélectriques multicouches by Anthony Coens( )

4 editions published in 2013 in French and held by 7 WorldCat member libraries worldwide

The main objective of this work is to study an organic hetero-structure (OLED) within a vertical micro-cavity in order to pave the way to the first organic laser diode under electrical pumping. The latter is still to be demonstrated whereas numerous optically pumped organic lasers have been reported. The issue deals with the low mobility of the organic semiconductors which limits the current density much below the laser threshold. It is also difficult to combine both high-quality-factor micro-cavities and electrodes inducing absorption losses. Our strategy consists in finding out the optimal parameter of an OLED structure to be used within a Fabry-Perot micro-cavity. After a bibliographic study that allow us to define the micro-cavity type to be used, we performed a numerical study, based on the transfer matrix method, in order to design and optimize dielectric multilayer mirrors for Fabry-Perot micro-cavity with quality factors as high as 15 000. Afterward, we experimentally, investigate OLED hetero-structures within Fabry-Perot micro-cavities. Our results indicate that a half wavelength thick OLED optimized for operation in a micro-cavity exhibits up to 15 000 Cd/m2 at 1500 mA/cm2 (DC). These OLEDs are then used with a half micro-cavity made with a bottom multilayer mirror ended semi-transparent and conductive anode. The absorption for different cathode thickness (Al and Al/Ag) has been investigated and an important spectral narrowing has been measured (11 nm FWHM). Finally, by using a full micro-cavity with two dielectric mirrors, the OLED emission exhibits a further spectral narrowing down to 4 nm. The electrical excitation of the OLED with 50 ns pulses results in current density up to 25 A/cm2 and luminescence up to 1,7.106 Cd/m2
Apprentissage incrémental des modèles d'action relationnels by Christophe Rodrigues( )

4 editions published in 2013 in French and held by 7 WorldCat member libraries worldwide

In this thesis, we study machine learning for action. Our work both covers reinforcement learning (RL) and inductive logic programming (ILP). We focus on learning action models. An action model describes the preconditions and effects of possible actions in an environment. It enables anticipating the consequences of the agent's actions and may also be used by a planner. We specifically work on a relational representation of environments. They allow to describe states and actions by the means of objects and relations between the various objects that compose them. We present the IRALe method, which learns incrementally relational action models. First, we presume that states are fully observable and the consequences of actions are deterministic. We provide a proof of convergence for this method. Then, we develop an active exploration approach which allows focusing the agent's experience on actions that are supposedly non-covered by the model. Finally, we generalize the approach by introducing a noisy perception of the environment in order to make our learning framework more realistic. We empirically illustrate each approach's importance on various planification problems. The results obtained show that the number of interactions necessary with the environments is very weak compared to the size of the considered states spaces. Moreover, active learning allows to improve significantly these results
Comportement mécanique et évolutions microstructurales sous compression quasi-statique et dynamique de polycristaux CFC et HC : effet de la taille des grains by Abdelouahab Ouarem( )

4 editions published in 2012 in French and held by 7 WorldCat member libraries worldwide

The present work is devoted to the analysis of the strain rate and grain size effects on the deformation mechanism activated during plastic deformation of two polycrystalline materials: (i) zinc (Zn), a crystal with hexagonal compact packing structure, having grain size in the micro and ultrafine grain ranges (~ 300 µm and 200 nm, respectively), loaded under quasi-static and dynamic compression conditions, up to a strain rate of ~ 10 5 s -1 (by use of a Direct Impact Hopkinson Pressure Bars (DIHPB); (ii) electrodeposited nickel (Ni), a face-centered cubic structure with grain size of 5 µm deformed in compression under dynamic conditions using DIHPB. Significant differences in terms of micro-mechanisms of deformation in the two regimes were found: (i) At lower strain rates, up to ~ 10 2 s -1 , dislocation-based plasticity was observed in both Ni and Zn. Extensive twinning occurred only in the case of micrometer grain-sized Zn, indicating a grain size dependence of twinning; (ii) In the dynamic regime (> 10 3 s -1 ) plastic deformation induced a significant increase of the temperature within the samples. This increase of temperature was significant enough to induce recovery and/or dynamic recrystallization. As consequence two phenomena were observed depending on the structure under investigation: for Ni, the resulting microstructure and mechanical properties were similar to that of the initial state, dominated by annealing twins and equiaxed and randomly oriented grains. For micro-grained Zn a tremendous grain refining was found. As a consequence, twinning was inhibited. To clarify this point, additional investigations were carried out on coarse-grained CP-Ti deformed in both quasi-static and dynamic regimes. It was found that twinning was the main deformation mechanism. Indeed, the larger the strain rate and grains size, the larger the twin density. On the one hand, these results clearly demonstrate the grain size effect on the occurrence of mechanical twinning in HCP materials. On the other hand, the effect of the strain rate on twinning was found to depend on the material under investigation. Compared to Ti, the lower homologous temperature T/T m of Zn probably plays a key role, as it may induce dynamic recovery/recrystallization as far as the present experimental conditions are concerned
Modèles hiérarchiques et topologiques pour le clustering et la visualisation des données by Nath-Quang Doan( )

4 editions published in 2013 in English and French and held by 7 WorldCat member libraries worldwide

This thesis focuses on clustering approaches inspired from topological models and an autonomous hierarchical clustering method. The clustering problem becomes more complicated and difficult due to the growth in quality and quantify of structured data such as graphs, trees or sequences. In this thesis, we are particularly interested in self-organizing maps which have been generally used for learning topological preservation, clustering, vector quantization and graph visualization. Our studyconcerns also a hierarchical clustering method AntTree which models the ability of real ants to build structure by connect themselves. By combining the topological map with the self-assembly rules inspired from AntTree, the goal is to represent data in a hierarchical and topological structure providing more insight data information. The advantage is to visualize the clustering results as multiple hierarchical trees and a topological network. In this report, we present three new models that are able to address clustering, visualization and feature selection problems. In the first model, our study shows the interest in the use of hierarchical and topological structure through several applications on numerical datasets, as well as structured datasets e.g. graphs and biological dataset. The second model consists of a flexible and growing structure which does not impose the strict network-topology preservation rules. Using statistical characteristics provided by hierarchical trees, it accelerates significantly the learning process. The third model addresses particularly the issue of unsupervised feature selection. The idea is to use hierarchical structure provided by AntTree to discover automatically local data structure and local neighbors. By using the tree topology, we propose a new score for feature selection by constraining the Laplacian score. Finally, this thesis offers several perspectives for future work
Applications de la métabolomique par spectrométrie par résonance magnétique nucléaire du proton dans les maladies graves du foie et leurs complications by Roland Amathieu( )

4 editions published in 2012 in French and held by 7 WorldCat member libraries worldwide

La métabolomique ouvre de nouvelles perspectives en médecine que cela soit dans le domaine du diagnostic, de l'évaluation du pronostic ou la gravité ou bien de la réponse à un traitement. Dans ce mémoire de thèse, nous nous sommes intéressés à l'application de la métabolomique en spectrométrie par résonance magnétique nucléaire du proton dans les maladies graves du foie d'origine alcoolique. A partir d'une sérothèque, la première étape de ce travail a été de déterminer les variations du métabolome en fonction du degré d'insuffisance hépatique chronique. Les profils métaboliques RMN des patients étaient différents en fonction de la gravité et pourraient permettre d'améliorer l'évaluation de la maladie. La seconde étape décrit les profils métabolomiques en fonction de la présence d'un carcinome hépatocellulaire ou non. Différents profils métabolomiques ont été trouvés en cas de carcinome hépatocellulaire et pourraient être prédictifs d'une récidive de la maladie après traitement curatif. Enfin dans une troisième étude, une signature métabolomique permettant d'identifier les patients présentant une aggravation aigüe de leur maladie et hospitalisés en réanimation a été trouvée. L'intérêt principal de ce dernier travail est de permettre un diagnostic précoce de l'insuffisance hépatique aigue sur cirrhose. Ces trois études ouvrent la voie à des véritables applications cliniques de la métabolomique, à condition qu'une validation sur de grandes cohortes confirme ces résultats. La métabolomique par RMN permettrait une évaluation plus précise de la gravité des patients présentant une cirrhose et une prise en charge mieux adaptée
Nouvelles réactions de couplage décarboxylatif catalysées par des sels de cuivre et de palladium - Nouvelles réactions de couplage aryl-aryle catalysées par des sels de nickel et de manganèse by Maël Poizat( )

3 editions published in 2013 in French and held by 6 WorldCat member libraries worldwide

The copper-catalyzed decarboxylation of aromatic carboxylic acids has been advantageously achieved by using aliphatic amines like N,N,N',N'-tetramethylethylenediamine (TMEDA) or hexamethylenetetramine (HMTA) as ligands instead of the aromatic heterocyclic amines (quinoline, phenanthroline) used until now. The improvement is significant since the reaction can be performed at a lower temperature (ca. 50 °C less) and the reaction time is clearly shorter. This new catalytic system was developed owing to a careful analysis of the reaction mechanism. The reaction conditions described herein also allow us to perform copper/palladium-catalyzed decarboxylative cross-coupling reactions between 120 to 140 °C instead of 170 °C. Thereby, biaryls and triarylethylenes compounds were obtained in good yields. Moreover, the multi-step synthesis of the anticancer agent (Z)-Tamoxifen was completed using a decarboxylative cross-coupling reaction as the key step. The results reported above could open the way to the development of low temperature procedures. It is worthy of note that, for large-scale applications, it is very advantageous to replace 1,10- phenanthroline by TMEDA which is clearly less expensive. A new reaction of demethylation-decarboxylation of o-methoxy aromatic carboxylic acids was also described. Finally, a cheap and user-friendly nickel/manganese catalytic system was developed for the efficient cross-coupling of functionalized aromatic chlorides with aromatic grignard reagents
Nouveaux dispositifs médicaux à base d'hydrogels de polysaccharides by Aïcha Abed( )

3 editions published in 2012 in French and held by 6 WorldCat member libraries worldwide

This work describes the development of new medical devices based on hydrogel of polysaccharides (pullulan and dextran). In recent years, our laboratory was interested in the biological properties of synthetic or natural polysaccharides and their interactions with endogenous growth factors and matrix components. So we had the idea to apply their properties to the design of a hybrid material composed of a polypropylene mesh coated with polysaccharides hydrogel. The first objective of this work is to improve the integration of materials currently used in clinical by using of hybrid prosthesis and understand the properties of these hydrogels in vitro and in vivo. In the second part of this work, based on the hydrogel properties a new system of storage and transport of tissue at room temperature was developed while limiting mechanical shocks and contamination associated with leaking fluids. Taking as a model of rat arteries, we validated this system in vitro and in vivo. Finally, we developed a new system for cryopreservation of cells and tissues. This hydrogel based polysaccharides reduces the quantities of toxic cryoprotectants agents during freezing. This method was validated in vitro and in vivo and in comparison with the reference procedure
Mise au point de microparticules polysaccharides injectables pour l'imagerie moléculaire de pathologies artérielles by Thomas Bonnard( Book )

3 editions published in 2014 in French and held by 5 WorldCat member libraries worldwide

Les pathologies cardiovasculaires et leurs conséquences représentent actuellement un problème de santé publique majeur dont la prise en charge pourrait être considérablement améliorée par le développement de nouvelles méthodes de diagnostic non invasives. Ce projet doctoral vise à développer des microparticules polysaccharides injectables dans la circulation sanguine permettant l'imagerie moléculaire des pathologies artérielles. Grâce à un procédé d'émulsion-réticulation, nous avons synthétisé ces microparticules qui sont d'une part fonctionnalisées avec du fucoïdane afin de pouvoir cibler la P-Sélectine qui est une molécule d'adhésion exprimée au niveau de la paroi artérielle lésée, et d'autre part, conjuguées à des agents de contraste afin d'apporter un signal en imagerie. Nous avons alors développé 2 outils d'imagerie moléculaire propres à 2 modalités classiques d'imagerie médicale. Afin de suivre les microparticules en tomographie par émission monophotonique de positons (TEMP), nous les avons radiomarquées avec du technétium 99m et pour les détecter en imagerie par résonance magnétique (IRM), nous les avons chargées avec des nanoparticules d'oxyde de fer superparamagnétiques. Nous avons ensuite validé l'efficacité de ces 2 outils d'imagerie moléculaire avec des essais précliniques en imagerie in vivo chez le petit animal sur des modèles de pathologies artérielles. Les résultats obtenus sont très encourageants et ces 2 outils d'imagerie moléculaire ont un fort potentiel clinique pour le diagnostic des pathologies artérielles. Nous avons également observé que les microparticules migrent dans la paroi artérielle dégradée au niveau des pathologies étudiées. Cette propriété singulière pourrait s'avérer très intéressante pour les futurs travaux qui consisteront à utiliser ce support pour véhiculer des molécules thérapeutiques au cœur des différentes pathologies artérielles
Coopération, conflits et décisions reproductives individuelles dans les sociétés annuelles de bourdons (bombus terrestris) by Pierre Blacher( )

3 editions published in 2014 in French and held by 5 WorldCat member libraries worldwide

L'existence de conflits est une caractéristique inhérente aux sociétés animales dont la structure génétique est non clonale. L'objectif principal de cette thèse était d'étudier les décisions reproductives individuelles des ouvrières en lien avec la dynamique coopération/conflit dans les sociétés annuelles du bourdon Bombus terrestris. Les colonies de B. terrestris présentent la particularité de se développer selon deux phases distinctes : une phase sociale caractérisée par une coopération altruiste des ouvrières et une phase de compétition durant laquelle les ouvrières entrent en conflit entre elles et avec la reine pour la production des mâles. L'analyse détaillée du comportement de dérive en conditions semi-naturelles a permis de démontrer l'existence d'une stratégie de reproduction supplémentaire pour les ouvrières ; quand le conflit s'exprime, certaines ouvrières fertiles quittent leur nid pour se reproduire dans les colonies voisines de la même espèce. Cette stratégie alternative de reproduction permet aux ouvrières d'éviter l'inhibition reproductive au sein de leur nid et d'optimiser ainsi leur inclusive fitness. Nos études ont de plus révélé que les ouvrières ajustent de façon adaptée leur comportement reproducteur à l'environnement social. La grande plasticité reproductive des ouvrières repose sur leur capacité à détecter et à traiter de multiples informations pertinentes de leur environnement social. Enfin, les résultats de cette thèse suggèrent l'existence d'une stratégie de défense coloniale contre le parasitisme reproductif des ouvrières. De part leur signature chimique spécifique, les parasites potentiels sont reconnus et discriminés comportementalement à l'entrée du nid par les gardes. Cette pluralité de stratégie de reproduction à la disposition des ouvrières est marginale au sein des hyménoptères sociaux, et les résultats obtenus de ce travail nous conduisent à discuter les traits d'histoire de vie de B. terrestris qui ont pu favoriser leur évolution
Une plateforme d'aide à l'acquisition et à la maintenance des règles métier à partir de textes règlementaires by Abdoulaye Guissé( )

3 editions published in 2013 in French and held by 5 WorldCat member libraries worldwide

Decision support systems are usually based on a set of business rules that constrain the information system data of a company. They can cope with e.g. computing the amount of taxes that is owed by a taxpayer as well as awarding benefits to clients of a company or controling the quality of an industrial process. This thesis has taken place in the framework of the European project OntoRule (ONTOlogies meet business RULEs). It focuses on the acquisition of rules from original regulatory texts written by business experts, belonging to the company or not. Our goal is to help experts, who best understant these texts, to translate rules from natural language toward a simpler and less ambiguous language. Moreover, we propose to help diagnosing maintenance problems caused by incoherencies happening either along the translation of rules, or when the original texts evolve. These rules are generally available in documents written in natural language, and their regulatory character marks the form of this language. In order to translate them into executable rules and to integrate them in decision making systems, text fragments embeding rules must first be identified. Then a transformation must be driven from natural language rules to formal rules. The problem is then to reduce the burden of this transformation, at the more heavy since this complex language can only be safely handled and interpreted by experts. We propose to equip the task of explicitating initial rules into an easily understandable expression, so that, relying on this expression, formalization and implementation work can start. In order to do so, we propose to business experts an interactive framework which helps them structuring and organizing better the explicitation work. This framework consists of : - a two-steps acquisition methodology : a first step organizes a search in the syntactic and semantic representations of texts in order to identify sentences which are relevant as rules ; and a second step consists in normalizing these sentences, through a controlled natural language as SBVR-SE, in order to simplify them, disambiguate them and make easier their translation into a formal language. - A documented semantic model that defines a navigation structure to assist acquisition and articulate regulatory texts, business concepts described by an ontology and the set of extracted rules. This structure, relying on its tracing functionality, also supports the management of incoherency in rules relatively to needs as identified in the initial, and of changes when initial texts evolve. The model is formally represented according to Semantic Web technologies (RDF, RDFS, RDFa, OWL, SPARQL) through an RDF graph. - a platform ; SemEx, which provides on the one hand interfaces to navigate and query an RDF graph with the help of the CORESE inference engine, on the other hand an interface to edit rules according to the acquisition methodology. SemEx is an open source application written in Java
Segmentation by convex active contour models : application to skin lesion and medical images by Quang Tung Thieu( )

3 editions published in 2013 in English and held by 5 WorldCat member libraries worldwide

Solving strategic and tactical optimization problems in city logistics by Paolo Gianessi( Book )

4 editions published in 2014 in English and held by 4 WorldCat member libraries worldwide

Urban freight transport is a matter of increasing concern in the economic, commercial, social and environmental operations of our cities, due to the constantly increasing growth and urbanization of the civilization. An improved managem ent of the traffic related to the freight transport can have a positive impact in many respects : security, congestion of the road network, noise and air pollution, costs. City Logistics studies the dynamic management of urban freight transport in order to deliver distribution systems solutions that may be suitable for both the community and freight carriers. This thesis originates from the ANR Project MODUM, which proposes a freight distribution system based on a ring of Urban Distribution Centers (UDCs) located in the outskirts of a city. In the first part, this system is studied from both a strategic and a tactical point of view. The Multicommodity-Ring Location Routing Problem (MRLRP) considers long-term decisions, i.e. the installation of the UDCs and the ring connection, without disregarding more tactical aspects. The MRLRP has been tackled by three solution methods, which proved effective on a large set of test instances. In the second part of the thesis, the Vehicle Routing Problem with Intermediate Replenishment Facilities (VRPIRF) is studied. The VRPIRF is a more tactical problem that arises in City Logistics each time both the multi-trip and the multi-depot features, i.e. the possibility for a vehicle to be reloaded at one of a set of facilities, are present. Several exact algorithms, namely two of type Branch&Cut and two of type Branch& Price, have been developed for this problem. computational experiments on benchmark instances taken from the literature have been conducted to assess their performance, leading to very promising results
Optimisation de nanostructures plasmoniques pour la détection et la caractérisation structurelle des protéines par Diffusion Raman Exaltée de Surface by Maximilien Cottat( Book )

3 editions published in 2014 in French and held by 4 WorldCat member libraries worldwide

Proteins play an important role in cells via their enzymatic activity and the irinteractions. Their functions are mainly based on the protein structure. In order to detect their presence and to characterize their structure, we used optical properties of nanostructures. The localized surface plasmon resonance (LSPR), as well as the surface enhanced Raman scattering (SERS), allowed us to detect various proteins. We also optimized nanostructures to build a sensitive, reproducible and specific biosensor based on SERS. Indeed, specific detection of one pathological biomarker, the Manganese Super Oxide Dismutase (MnSOD) protein, was investigated by using optically optimized and aptamer-functionalized nanostructures. Using this system, we were able to detect the MnSOD at physiological concentration in body fluids, such as serum and saliva. Finally, the structural study of the Spleen Tyrosine kinase (Syk) protein by SERS, allowed us to demonstrate that its structure varied with its phosphorylation levels. A complementary Western Blot analysis showed that the Syk kinase activity depended also on its phosphorylation state, meaning that the structure and the activity of Syk were linked. Altogether, these data contributed to a better understanding of the interface between physics and biology
Approche perceptuelle pour la retouche d'images : algorithmes, évaluation et détection by Thanh Trung Dang( Book )

3 editions published in 2014 in French and English and held by 4 WorldCat member libraries worldwide

Image inpainting technique has emerged as one of the efficient solutions for restoring degraded images and even video and 3D visual contents. It is essential for restoration and conservation of archeological objects. Indeed, during the excavation of historic sites, many valuable artifacts such as statues, buildings, wall paintings, etc., have been unearthed and recovered. Unfortunately, most of them have been damaged or fractured in ancient times. With the aim to learn from these objects, digital techniques are used to restore them using some a priori knowledge provided by archeologists and artists. This helps to reconstruct, preserve and maintain these valuable artistic works. Recently, advances of computer technology and image acquisition systems made possible the transition from traditional manual retouching methods to digital techniques. It has opened up a very new and interesting research field within image processing, namely digital image inpainting.In this thesis, our work aims at analyzing and reviewing the state-of-the-art methods for image inpainting. Three groups of inpainting methods are identified. The advantages and drawbacks of each approach are analyzed using objective and subjective criteria. Based on this review, a new approach of image inpainting is introduced and compared to literature. The proposed method provides good performance in terms of quality and computation efficiency. Another contribution lies in the proposal of a new quality metric dedicated to image inpainting. To the best of our knowledge the inpainted images are very often evaluated subjectively or by means of some objective metrics far from being adapted to the peculiarities of image inpainting criteria. The last contribution of this work is a less investigated problem related to inpainting detection. This is motivated by the fact that, due to extensive research and rapid growth of technology, the output quality of inpainting algorithms became more than ever realistic and sophisticated. The inpainted regions are hard to detect by viewers, even for experts. As a result, these inpainted images could be used for different purposes, including digital tampering. Therefore, the last topic of the work is devoted to inpainting detection, also seen as an inverse problem of inpainting. Although, many papers have been introduced for forgery detection, there is almost no study about image inpainting forgery. Accordingly, a novel approach for inpainting detection is introduced based on the knowledge gathered in the previous steps of the thesis. Finally, the performance of proposed solutions is carefully evaluated with regards to human judgment as well as in comparison with the existing methods though a series of experimental studies
Reconnaissance de comportements complexes par traitement en ligne de flux d'évènements by Ariane Piel( Book )

3 editions published in 2014 in French and held by 4 WorldCat member libraries worldwide

Recognising complex predefined behaviours by the analysis of event flows (Complex Event Processing - CEP) allows to interpret and react to large quantities of data which one would not be able to apprehend alone. In this Ph.D. thesis, we provide a general theoretical framework for CEP through a purely formal approach ensuring the possibility to check and analyse the recognition process. We define a language, the chronicle language, allowing the description of the complex behaviours to be recognised. We formalise the notion of chronicle recognition through a set semantics based on an arborescent representation of recognitions. In order to use this framework, we then develop two models of the recognition process. The first relies on coloured Petri nets and allows the validation of recognition principles including concurrency and modularity issues. The second model directly implements the mathematical formalism in a C++ library, Chronicle Recognition Library (CRL), which is available in open source. We use this implementation to fulfil two applications linked to the insertion of unmanned aircrafts in controlled airspace. The first application oversees the consistency of an unmanned aircraft system inside air traffic in case of communication link breakdowns. This application allows, on the one hand, to check the consistency of the procedures currently followed in case of failures; and, on the other hand, to complete these procedures with alarms in case of unavoidable situations caused by human errors. The second application oversees that the security procedures of an unmanned aircraft flying through controlled or uncontrolled airspace are correctly followed
Autour des équations d'Einstein dans le vide avec un champ de Killing spatial de translation by Cécile Huneau( Book )

3 editions published in 2014 in French and held by 4 WorldCat member libraries worldwide

Dans cette thèse, nous étudions les équations d'Einstein dans le vide avec un champ de Killing de translation. En présence de cette symétrie, les équations d'Einstein dans le vide en dimension 3+1 peuvent s'écrire, dans le cas polarisé, comme un système d'équations d'Einstein couplées à un champ scalaire en dimension 2+1. Dans la première partie de cette thèse, nous étudions les équations de contraintes dans le cas asymptotiquement plat. Les équations de contraintes sont des équations de compatibilité qui doivent être satisfaites par les données initiales. Nous montrons l'existence de solutions pour des données assez petites, et introduisons un développement asymptotique faisant intervenir des quantités correspondant aux charges globales. Dans une deuxième partie nous montrons la stabilité de l'espace-temps de Minkowski avec un champ de Killing de translation, en temps exponentiellement grand par rapport à la petitesse de la donnée initiale. Nous travaillons dans les coordonnées d'onde généralisées. Nous introduisons une famille de métriques Ricci plates, et imposons le comportement asymptotique de nos solutions à l'extérieur du cône de lumière en choisissant un élément de cette famille de manière adéquate. Ce choix permet la convergence de nos solutions à l'intérieur du cône de lumière vers la solution de Minkowski. Dans la dernière partie de cette thèse nous étudions les équations de contraintes dans le cas compact hyperbolique. Nous montrons l'existence d'une équation limite associée aux équations de contraintes
Développement de nano-catalyseurs pour des réactions de couplage C-C by Emilie Nehlig( Book )

3 editions published in 2014 in French and held by 4 WorldCat member libraries worldwide

Ces dernières années, l'intérêt porté à l'obtention de nouveaux systèmes catalytiques a connu un essor fulgurant. Ceci est lié, en particulier, aux applications industrielles variées qui s'étendent de la chimie fine à la chimie pharmaceutique. De nombreux catalyseurs ont ainsi été développés pour un nombre toujours croissant de réactions organiques. Néanmoins, la plupart des catalyseurs homogènes sont difficiles à adapter aux procédés industriels du fait de problèmes de séparation et de régénération. De plus, même efficaces, la plupart des catalyseurs contiennent des métaux nobles, coûteux et difficiles à recycler. C'est pourquoi, de nouveaux protocoles plus économiques et plus respectueux de l'environnement ont besoin d'être recherchés. L'utilisation de nanoparticules magnétiques comme support catalytique en synthèse organique représente une solution innovante pour répondre aux problèmes catalytiques rencontrés. Le but de ce travail consiste à concevoir des nano-catalyseurs magnétiques et à évaluer leur activité catalytique ainsi que leur recyclage pour des réactions de couplage carbone-carbone très utilisées en synthèse organique. Des nanoparticules de Maghémite synthétisées dans en milieux aqueux sont ensuite stabilisées en surface par des agents complexants possédant une fonction terminale qui permettra de les fonctionnaliser avec le catalyseur désiré (L Proline, peptides, alcaloïde, Palladium). Ces nanomatériaux hybrides, constitués d'un cœur inorganique et d'une couche organique, ont été caractérisés par diverses techniques afin de déterminer leurs propriétés. Leurs activités ont été évaluées sur des réactions de couplage carbone-carbone modèles d'aldolisation, d'addition 1,4 de Michael et la réaction de Suzuki-Miyaura
Nouveaux rôles anti-tumoraux de STAT1 : expression des immunoglobulines et réparation de l'ADN by Elodie Lemadre( Book )

3 editions published in 2014 in French and held by 4 WorldCat member libraries worldwide

The transcription factor STAT1, as a major effector of interferon, plays a key role in innate immunity. Through its strong anti-proliferative and pro-apoptotic properties STAT1 is also considered as a tumor suppressor. The aim of this project was to delineate new potential tumor suppressor properties for STAT1 in two signaling mechanisms: i) Ig expression in plasmacytoid cells and ii) cellular response to genotoxic stress. Our kinetic experiments, upon “de novo” expression of STAT1 in a rare STAT1 -deficient cell line showed its modulation of membrane IgG expression. The underlying mechanism involves a STAT1 -dependent inactivation of STAT3 and subsequently a decreased expression of BLIMP1, a major contributor to plasma cell differentiation. Since STAT1, like STAT3, is able to bind to the BLIMP1 promoter elements a transcriptional interference cannot be excluded. During alkylating agent treatment with MNNG we have observed the presence of STAT1 in DNA repair complex. STAT1 expression allows the recruitment into a MLH1/p53 complex of the kinase c-Abl. This complex leads to cytotoxic dependence on c-Abl kinase activity, an efficient DNA repair with a transient cell cycle arrest and to signaling mechanisms toward cell survival. At longer term of exposure STAT1 also lead to cellular resistance to treatment. These results provide evidences for new anti-tumor roles of STAT1 in two major regulatory systems and indicate STAT1 as a potential therapeutic target
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Alternative Names
École doctorale 146

École doctorale Sciences, Technologies, Santé Galilée

ED 146


Galilée École doctorale (Villetaneuse, Seine-Saint-Denis)

French (53)

English (15)