WorldCat Identities

Noirez, Philippe

Works: 7 works in 7 publications in 2 languages and 11 library holdings
Roles: Author, Opponent
Publication Timeline
Most widely held works by Philippe Noirez
Croissance et maturation du muscle strié squelettique lors de la régénération chez le rat : influences physiologiques (activité neuromusculaire, hormones) by Philippe Noirez( )

1 edition published in 2000 in French and held by 2 WorldCat member libraries worldwide

Nous déterminons si un niveau normal de charge mécanique (cm), d'androgènes anabolisants stéroïdiens (AAS) ou de transforming growth factor (TGF-1) est indispensable à la régénération du muscle strié squelettique. De plus, nous étudions les effets sur la régénération musculaire de l'augmentation de la charge mécanique, de l'administration d'AAS associée ou non à une augmentation de l'activité physique (AAS + EXE), et d'administrations d'anti-inflammatoires stéroïdien (AIS) ou non. Un cycle de dégénération-regénération est induit par une injection de myotoxique (venin de serpent) dans les muscles lent et rapide de rats mâles. La croissance des muscles régénérés est étudiée à travers la masse musculaire, et la concentration en protéines et en chaînes lourdes de la myosine (MHC). Leur maturation est évaluée par electrophorèse à travers l'expression des MHC matures. Les résultats indiquent qu'une CM normale est indispensable à la maturation (expression de MHC-1) du muscle lent régénéré. De plus, les AAS ne jouent pas un rôle essentiel dans la régénération (croissance et maturation) musculaire. Enfin, le TGF-1 semble être impliqué dans la maturation d'un muscle rapide (expression des MHC rapides) au cours de la régénération. Par ailleurs, nous montrons que pour le muscle rapide régénéré, l'administration d'AIS aurait une influence néfaste (diminution de la croissance) ; c'est l'inverse dans le cas de l'augmentation de la CM (diminution de l'expression de la MHC-2b). Pour le muscle régénéré lent, l'augmentation et la diminution de CM, AAS + EXE et l'administration d'AIS exerceraient une influence néfaste (altération de la maturation) ; c'est l'inverse dans le cas d'administration d'AAS (augmentation de l'expression de MHC-1). En conclusion, l'environnement (CM, TGF-1) semble indispensable à la régénération du muscle squelettique. De plus, l'augmentation du niveau de certains facteurs physiologiques (CM, AAS, AIS) modulent la régénération du muscle
An integrative modeling approach to the age-performance relationship in mammals at the cellular scale by Geoffroy Berthelot( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

<> by Philippe Noirez( )

1 edition published in 2005 in English and held by 2 WorldCat member libraries worldwide

The age-performance relationship in the general population and strategies to delay age related decline in performance by Geoffroy Berthelot( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Medical Reasons Behind Player Departures From Male and Female Professional Tennis Competitions( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Background: The number of retirements, withdrawals, and "lucky losers" (the replacement of a player who withdraws before the start of the tournament by a losing player from the qualifying round) from professional tennis tournaments has increased, but the reasons behind such departures have not yet been analyzed. An official consensus statement has been conducted to allow a general categorization of injuries in tennis. Purpose: To determine the reasons for departure and injury rates in professional tennis. Study Design: Descriptive epidemiology study. Methods: All reasons for departures were collected from official Association of Tennis Professionals (ATP) and Women's Tennis Association (WTA) web pages. All tournaments apart from the 4 major competitions (the Australian Open, French Open, Wimbledon, and US Open) were included for the period 2001-2012 for men and women. Personal data, tournament information, surface, match setting, date, and reason were obtained for each departure scenario. Results: Variations in departure and injury rates were seen throughout the season. Women left and were injured significantly more than men. Women mainly left because of thigh injuries, whereas men left mainly because of back injuries. Playing surface only had an influence on the risk of lower back injuries. Only women's departures were affected by the tournament round. Conclusion: A high number of departures from tournaments have occurred during the past 10 years on the ATP and WTA circuits. Injuries were the main reasons of these departures, regardless of the type of departure and player sex. The back and thigh were the main locations of injuries for men and women, respectively
Impact de la citrulline sur le métabolisme du tissu adipeux by Nolwenn Joffin( )

1 edition published in 2015 in French and held by 1 WorldCat member library worldwide

Rôle de la neuréguline 1 dans les adaptations du métabolisme énergétique en condition de pathologies métaboliques : effets de l'activité physique. by Gaël Ennequin( )

1 edition published in 2015 in French and held by 1 WorldCat member library worldwide

Neuregulin 1 (NRG1) is a cytokine that belongs to the epidermal growth factors family. NRG1can be released during exercise and can be define as a myokine. Initially studied for its rolein growth and maturation, NRG1 can also regulate glucose homeostasis in vitro. Thus, theaim of this work was to investigate the effect of training and metabolic disorders on NRG1pathway and its role in energy metabolism. Results showed that NRG1 pathway was notaltered in skeletal muscle of obese rats. Conversely, endurance training combined with awell-balanced diet improved NRG1 pathway activation in skeletal muscle of obese. Indeed, 8weeks of training and diet increased the cleavage of NRG1 and the activation of its receptorErbB4 through the activation of the metalloprotease ADAM17. Moreover, acute and chronictreatment improved glucose tolerance in diabetic mice (db/db). Acute treatment loweredglycemia by activating ErbB3, Akt and FOXO1 in the livre. Thus, NRG1 might play a key role inthe regulation of glucose homeostasis in people who suffers from metabolic disorders.Training might a good tool to activate this pathway in skeletal muscle
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