WorldCat Identities

Lee, Geoffrey

Overview
Works: 20 works in 21 publications in 2 languages and 253 library holdings
Genres: Academic theses 
Roles: dgs, Other, Contributor, Author
Publication Timeline
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Most widely held works by Geoffrey Lee
Saturation Solubility Determination of a Drug in Thin Polymer Films and its Influence on Permeation by Simone Reismann( )

1 edition published in 2011 in German and held by 29 WorldCat member libraries worldwide

Spray-Drying of Enzymes on the Bench-Top Scale with lengthened Chamber Retention Time by Joachim Schäfer( )

1 edition published in 2015 in English and held by 27 WorldCat member libraries worldwide

Quantitative measurements of shrinkage and cracking during freeze-drying of amorphous cakes by Sabine Ullrich( )

1 edition published in 2014 in English and held by 27 WorldCat member libraries worldwide

Studies on the Manufacture & Spray Drying of Liposomes and Membrane Lipids by Julia Staudenecker( )

1 edition published in 2016 in English and held by 27 WorldCat member libraries worldwide

Thermodynamic Activity in PSA Matrices: Determination and Influence on Skin Permeation by Anders Kunst( )

1 edition published in 2015 in English and held by 27 WorldCat member libraries worldwide

Rapidly dissolving cryopellets for coagulation diagnostics by Matthias Erber( )

1 edition published in 2014 in English and held by 27 WorldCat member libraries worldwide

Nanokristalle schwerlöslicher Wirkstoff: Einfluss von Prozessschritten und Formulierung auf Redispergierbarkeit und verbesserte Auflösegeschwindigkeit by Veronika Braig( )

1 edition published in 2020 in German and held by 20 WorldCat member libraries worldwide

Measurement of Saturation Solubility of Drugs in Stratum Corneum Lipid Matrices by Anne Mundstock( )

1 edition published in 2014 in English and held by 20 WorldCat member libraries worldwide

Kinetics of protein damage during evaporative drying of levitated microdroplets by Elke Lorenzen( )

1 edition published in 2013 in English and held by 16 WorldCat member libraries worldwide

Organic and Hybrid Nanoparticles for Controlled Instigation of Inertial Cavitation Using Therapeutic Ultrasound by Alexander Grebner( )

1 edition published in 2017 in English and held by 10 WorldCat member libraries worldwide

Different Storage Conditions Influence Biocompatibility and Physicochemical Properties of Iron Oxide Nanoparticles( )

1 edition published in 2015 in English and held by 3 WorldCat member libraries worldwide

Investigation of the inertial cavitation activity of sonosensitive and biocompatible nanoparticles for drug delivery applications employing high intensity focused ultrasound by Benedikt George( )

1 edition published in 2019 in English and held by 3 WorldCat member libraries worldwide

Abstract: An approach to improve chemotherapy, while minimizing side effects, is a local drug release close to the tumorous tissue. For this purpose, the active drug component is often bound to nanoparticles employed as drug carriers. In the present study, we investigate sonosensitive, biocompatible poly-(L)-lactic acid (PLA) nanoparticles, which shall be used as drug carriers. For drug release, High Intensity Focused Ultrasound (HIFU) will be employed to introduce inertial cavitation, which separates the active drug component from the drug carrier. The cavitation effect generates an acoustic noise signal, which characterizes the cavitation activity and is expected to serve simultaneously as an indicator for the release of the active drug component. Depending on the ultrasound frequency, different acoustic levels of the inertial cavitation activity were measured. Investigations using a setup for passive cavitation detection (PCD) deliver quantitative results regarding the frequency dependence of the cavitation activity level of nanoparticles and reference media
Determination of the cavitation pressure threshold in focused ultrasound wave fields applied to sonosensitive, biocompatible nanoparticles for drug delivery applications by Benedikt George( )

1 edition published in 2020 in English and held by 3 WorldCat member libraries worldwide

Abstract: Employing sonosensitive nanoparticles as carriers of active pharmaceutical ingredients emerges in ultrasonic Drug Delivery. Drug release can be initiated by focused ultrasound via the effect of inertial cavitation in certain target areas of particle loaded tissue. For stimulating inertial cavitation, a specific peak rarefaction pressure threshold must be exceeded. This pressure threshold has to be determined in order to estimate the risk of tissue damage during the drug release procedure. Therefore, this study provides a method to reliably verify the cavitation pressure threshold of sonosensitive and biocompatible nanoparticles
Development of sonosensitive Poly-(L)-lactic acid nanoparticles by Pia-Theresa Hiltl( )

1 edition published in 2017 in English and held by 3 WorldCat member libraries worldwide

Abstract: Due to serious side effects of traditional chemotherapeutic treatment, novel treatment techniques like targeted drug delivery, which allows a reduction of the overall dosage of drugs, are investigated. It is worth mentioning that at the same time, precise drug delivery offers an increased dosage of chemotherapeutic drugs in the tumorous area employing the EPR effect. Therefore, vehicles smaller than 400 nm can be used to pass the poorly aligned endothelial cells of tumour vessels passively through their fenestrations. In a subsequent step, the chemotherapeutic drugs need to be released. One possibility is an ultrasoundbased release via inertial cavitation. Thereby, it is desirable to restrict the drug release to a narrow range. Thus, the cavitation inducing ultrasound wave has to be focused to that region of interest. Ultrasound frequencies of more than 500 kHz enable sufficient focusing, however, inertial cavitation occurs primarily at much lower frequencies. In order to afford inertial cavitation at 500 kHz, either bigger particles in the range of micrometres are needed as cavitation nucleus, which is not possible due to the EPR effect or high acoustic pressure is needed to generate inertial cavitation. Nevertheless, this high pressure is inappropriate for clinical applications due to thermal and mechanical effects on biological tissue
Inertial cavitation of lyophilized and rehydrated nanoparticles of poly(L-lactic acid) at 835 kHz and 1.8 MPa ultrasound by Pia Hiltl( )

2 editions published in 2019 in English and held by 3 WorldCat member libraries worldwide

Functionalization Of T Lymphocytes With Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles For Magnetically Controlled Immune Therapy by Marina Mühlberger( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Loading of Primary Human T Lymphocytes with Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Does Not Impair Their Activation after Polyclonal Stimulation by Marina Mühlberger( )

1 edition published in 2020 in English and held by 2 WorldCat member libraries worldwide

Targeting alarmins to accelerate healing by Geoffrey Lee( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Tangential Flow Ultrafiltration Allows Purification and Concentration of Lauric Acid-/Albumin-Coated Particles for Improved Magnetic Treatment by Jan Zaloga( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

 
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Languages
English (19)

German (2)