WorldCat Identities

Shattock, Robin J.

Overview
Works: 17 works in 17 publications in 1 language and 28 library holdings
Roles: Contributor, Other
Publication Timeline
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Most widely held works by Robin J Shattock
Rational design of HIV vaccines and microbicides: report of the EUROPRISE annual conference 2011 by Nicolas Ruffin( )

1 edition published in 2012 in English and held by 2 WorldCat member libraries worldwide

Infection of rhesus macaques with a pool of simian immunodeficiency virus with the envelope genes from acute HIV-1 infections by Kendall C Krebs( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Preclinical evaluation of lime juice as a topical microbicide candidate by Patricia S Fletcher( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

Discrete partitioning of HIV-1 Env forms revealed by viral capture by Daniel J Stieh( )

1 edition published in 2015 in English and held by 2 WorldCat member libraries worldwide

Aggregate complexes of HIV-1 induced by multimeric antibodies by Daniel J Stieh( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

A heterogeneous human immunodeficiency virus-like particle (VLP) formulation produced by a novel vector system by Joshua Pankrac( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Expressing anti-HIV VRC01 antibody using the murine IgG1 secretion signal in Pichia pastoris by Rochelle Aw( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

Dynamic electrophoretic fingerprinting of the HIV-1 envelope glycoprotein by Daniel J Stieh( )

1 edition published in 2013 in English and held by 2 WorldCat member libraries worldwide

Selective transmission of R5 HIV-1 variants: where is the gatekeeper? by Jean-Charles Grivel( )

1 edition published in 2010 in English and held by 2 WorldCat member libraries worldwide

Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence by Kwinten Sliepen( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Innate immunity against HIV: a priority target for HIV prevention research by EUROPRISE Working Group( )

1 edition published in 2010 in English and held by 2 WorldCat member libraries worldwide

Candidate polyanion microbicides inhibit HIV-1 infection and dissemination pathways in human cervical explants by Patricia S Fletcher( )

1 edition published in 2006 in English and held by 2 WorldCat member libraries worldwide

Development of vaccine platforms for membrane display of surface antigens using HIV-1 Env as model immunogen by Yoann Leopold Thomas Aldon( )

1 edition published in 2019 in English and held by 1 WorldCat member library worldwide

The synergistic effects of combining TLR ligand based adjuvants on the cytokine response are dependent upon p38/JNK signalling( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Maraviroc and reverse transcriptase inhibitors combinations as potential preexposure prophylaxis candidates( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Abstract : Supplemental Digital Content is available in the text Abstract : Objective: Receptive anal intercourse in both men and women is associated with the highest probability for sexual acquisition of HIV infection. As part of a program to develop an effective prevention strategy, we performed an ex-vivo preclinical evaluation to determine the efficacy of multiple double combinations of maraviroc (MVC) and reverse transcriptase inhibitors (RTIs). Design: The entry inhibitor, MVC, a nucleotide RTI, tenofovir and two non-nucleoside RTIs, UC781 and TMC120 (dapivirine, DPV), were used in double, combinations against a panel of CCR5-using clade B and clade C HIV-1 isolates and against MVC-escape variants. A gel-formulated version of MVC-DPV combination was also tested. Methods: Indicator cells, cocultures of immature dendritic cells with CD4 + T cells, and colorectal tissue explants were used to assess antiviral activity of drug combinations. Results: All dual MVC-RTI combinations tested inhibited MVC-sensitive and resistant isolates in cellular and colorectal explants models. All the combinations were positive with no reduction in the activity of MVC. In tissue explants, the combinations against all viral isolates tested produced an increase in the activity of MVC. An initial gel-formulation of MVC-DPV combination showed greater and prolonged antiviral activity of MVC in mucosal tissue explants. Conclusion: This study demonstrates that combinations based on antiretroviral drugs inhibiting HIV transmission at viral entry and reverse transcription have potential as prevention strategies against colorectal transmission of HIV-1 including MVC-resistant isolates. Preclinical evaluation with colorectal tissue explants indicates that a gel-formulation of MVC-DPV is an effective candidate colorectal microbicide
The impact of prime-boost interval on antibody responses in HIV vaccination by Sven Kratochvil( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes by Paul J Peters( )

1 edition published in 2015 in English and held by 0 WorldCat member libraries worldwide

 
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Audience Level
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Audience level: 0.96 (from 0.85 for Developmen ... to 1.00 for Infection ...)

Languages
English (17)