WorldCat Identities

Savage, Paul B.

Overview
Works: 33 works in 38 publications in 1 language and 48 library holdings
Genres: Textbooks  Software 
Roles: Contributor, Other, Author
Classifications: QD253, 547
Publication Timeline
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Most widely held works by Paul B Savage
Organic chemistry by Maitland Jones( Book )

1 edition published in 2010 in English and held by 5 WorldCat member libraries worldwide

Helps students to understand the basics of organic chemistry, offering clear explanations and cross-references to topics previously covered. This textbook, which is heavily illustrated in colour, also contains many end-of-chapter problems and a study guide
Organic reaction animations by Steven A Fleming( )

4 editions published between 1998 and 2008 in English and held by 3 WorldCat member libraries worldwide

This software ancillary is a addition to teaching package : ORGANIC CHEMISTRY. Like the Jones text, Organic reaction animations focuses on helping students to learn the "why" of organic reactions, not just the "what" and "how". The program includes short (approximately one minute) animations of thirty key organic reactions based on high-level calculations performed with the aid of the program Spartan by Wavefunction. Each reaction is represented in four ways : ball-and-stick model, space-filling model, ball-and-stick model with the highest occupied molecular orbitals (HOMO) superimposed, and ball-and-stick model with the lowest unoccupied molecular orbitals (LUMO) superimposed. The animations are particularly helpful for students who find it hard to visualize molecular orbitals and want to understand the flow of electrons in organic reactions
Bactericidal activities of the cationic steroid CSA-13 and the cathelicidin peptide LL-37 against Helicobacter pylori in simulated gastric juice by Katarzyna Leszczynska( )

1 edition published in 2009 in English and held by 2 WorldCat member libraries worldwide

Species Specific Differences of CD1d Oligomer Loading In Vitro by Daniel Paletta( )

2 editions published in 2016 in English and held by 2 WorldCat member libraries worldwide

Use of ceragenins as a potential treatment for urinary tract infections by Urszula Wnorowska( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

In vitro activities of antimicrobial peptides and ceragenins against Legionella pneumophila by A. Seher Birteksoz-Tan( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

N, N-Bis-(8-hydroxy-5-Nitroquinolin-7-ylmethyl)diaza-18-Crown-6, a Chemosensor for Mercury Ions( Book )

2 editions published in 2000 in English and held by 2 WorldCat member libraries worldwide

Diaza-18-crown-6 appended with two 8-hydroxy-5-nitroquinoline groups acts as an effective fluorescent chemosensor for Hg(2+). The apparent PK(a)s of the phenolic protons on the ligand decrease significantly in the presence of mercury allowing formation of a neutral, fluorescent complex. The ligand responds selectively to Hg(2+) in the presence of other metal ions including alkali metal and alkaline earth cations, Zn(2+), Cd(2+), Ni(2+) and Cu(2+)
Anaerobic bacteria growth in the presence of cathelicidin LL-37 and selected ceragenins delivered as magnetic nanoparticles cargo by Bonita Durnaś( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

Evaluation of the in vitro activity of ceragenins against Trichomonas vaginalis by Zubeyde Akin Polat( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

A Convenient Synthesis of Novel Fluorophores: Macrocyclic Polyamines Containing Two Dansylamidoethyl Side Arms( )

1 edition published in 2000 in English and held by 2 WorldCat member libraries worldwide

Bis-(quinolin-8-ylmethyl)-substituted Diaza-18-crown-6: Synthesis and Metal Ion Complexation Properties( )

1 edition published in 2000 in English and held by 1 WorldCat member library worldwide

N, N-Bis-(quinolin-8-ylmethyl)diaza-l 8-crown-6 (L) was prepared in a high yield by treating diaza-18-crown-6 with 8-bromomethylquinoline in the presence of triethylamine. Ligand L interacted strongly with Na(+), K(+), Mg(2+), Co(2+), Cu(2+), Ni(2+), and Zn(2+) as shown by calorimetric titration and UV-Visible spectrophotometric techniques. The ligand exhibited a good selectivity for Cu(2+) over Ni(2+). The calorimetric titration indicated that ligand L forms both mononuclear and binuclear complexes with Cu(2+)
Diaza- 18-Crown-6 Ligands Containing Two Aminophenol Side Arms: New Heterobinuclear Metal Ion Receptors( )

1 edition published in 1999 in English and held by 1 WorldCat member library worldwide

Three diaza-18-crown-6 ligands substituted with two aminophenol side arms were synthesized as possible heterobinuclear metal ion receptors. Bis(p-aminophenol)-substituted diaza-18-crown-6 ligand (13) was prepared by treating the diazacrown with alpha-bromo-4-nitro-o-cresol in the presence of N, N-diisopropylethylamine followed by reduction of the nitro groups. Bis(o-aminophenol)-substituted diaza-18-crown-6 ligands (11 and 12) were prepared in two steps by the aminomethylation of either an 0-nitrophenols or o-(trifluoroacetamido)phenol followed by reduction of the nitro groups or hydrolysis of the trifluoroacetamide groups. All new bisphenol-armed diazacrown ligands were purified by ultrasonication in MeOH followed by filtration and drying. Interaction of the ligands with Na(+), K(+), Ag(+), and Cu(2+) was evaluated by a calorimetric titration technique at 25 deg C in MeOH. The complexes of Ag(+) and Cu(2+) are much more stable than those of Na(+) and K(+). Heterobinuclear complexes were observed for 11-Cu(2+)- Na(+) and 12-Cu(2+)-Na(+) but not for 13-Cu(2+)-Na(+) or for 12-Cu(2+)-Ag(+)
Endogenous ligands of natural killer T cells are alpha-linked glycosylceramides( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Preliminary Complexation Studies of Bis-(8-Hydroxyquinoline)-substituted Tetraaza-15-crown-5 with Various Metal Ions( )

1 edition published in 1999 in English and held by 1 WorldCat member library worldwide

Complexation of bis(8-hydroxyquinoline)-substituted tetraaza-15-crown-5 with Cu(2+), Co(2+), Ni(2+), Zn(2+), Cd(2+), and Pb(2+) was evaluated potentiometrically in aqueous solution (0.10 M Me4NCl) at 25 deg C. Ligand 1 formed very stable complexes with these metal ions. The UV-Vis spectra of ligand 1 and its complexes were examined in an aqueous acetic acid buffer solution (pH 4.7). The 1-Cu(2+) complex provided a new absorption band at 258 nm
New Tetraazacrown Ethers Containing Two Pyridine, Quinoline, 8-Hydroxyquinoline, or 8-Aminoquinoline Sidearms( )

1 edition published in 1999 in English and held by 1 WorldCat member library worldwide

A series of macrocyclic tetraazacrown ethers containing two pyridine, quinoline, 8-hydroxyquinoline, or 8-aminoquinoline sidearms has been prepared. Crab-like cyclization of bis(alpha-chloroacetamide)s and diamines followed by reduction of the cyclic diamides was used to synthesize the selected crown ethers containing two unsubstituted macroring nitrogen atoms. The preparation of the macrocycles with sidearms was accomplished by reductive aminatlon of the proper aldehydes with the crown ethers using sodium triacetoxyborohydride (NaBH(OAc)3) as the reducing agent. The 8-hydroxy- quinoline, and 8-aminoquinoline-containing macrocycles were synthesized by reductive amination of 8-acetoxyquinoline, 2-carboxaldehyde or 8-nitroquinoline-2-carboxaldehyde followed by removing the acetate groups or reducing the nitro groups to amino groups, respectively. Complexation of ligand 22 with Cu2+, Co2+, Ni2+, Zn2+, Cd2+, and Pb2+ was evaluated potentiometrically in aqueous solution (0.10 M Me4NCl) at 25 deg C. Ligand 22 formed very stable complexes with these metal ions. The UV-vis spectra of 22 and its complexes were examined in an aqueous acetic acid buffer solution (pH 5). The 22-Cu2+ complex provided a new absorption band at 258 nm
Organic chemistry by Maitland Jones( Book )

1 edition published in 2010 in English and held by 1 WorldCat member library worldwide

Synthesis of Bis(8-aminoquinoline)-substituted Tetraazacrown Ethers by a Reductive Amination Process( )

1 edition published in 1999 in English and held by 1 WorldCat member library worldwide

Four new tetraazacrown ethers containing two 8-aminoquinoline side arms were prepared first by reductive amination of 8-nitroquinolin-2-carboxaldehyde with the appropriate tetraazacrown ether containing two NH functions (see our Technical Report No. 4). The resulting bis(8-nitro-2-quinolinylmethyl)-substituted tetraazacrown ethers were reduced by iron and HCl to form the N, N'-bis(8-amino-2-quinolinylmethyl)-substituted tetraazacrown ether ligands
The processing and presentation of lipids and glycolipids to the immune system( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

The recognition of CD1-lipid complexes by T cells was discovered 20 years ago and has since been an emerging and expanding field of investigation. Unlike protein antigens, which are presented on MHC class I and II molecules, lipids can only be presented by CD1 molecules, a unique family of MHC-like proteins whose singularity is a hydrophobic antigen-binding groove. The processing and loading of lipid antigens inside this groove of CD1 molecules require localization to endosomal and lysosomal subcellular compartments and their acidic pHs. This particular environment provides the necessary glycolytic enzymes and lipases that process lipid and glycolipid antigens, as well as a set of lipid transfer proteins that load the final version of the antigen inside the groove of CD1. The overall sequence of events needed for efficient presentation of lipid antigens is now understood and presented in this review. However, a large number of important details have been elusive. This elusiveness is linked to the inherent technical difficulties of studying lipids and the lipid-protein interface in vitro and in vivo . Here, we will expose some of those limitations and describe new approaches to address them during the characterization of lipids and glycolipids antigen presentation
Photophysical Properties of Bis-8-Hydroxyquinoline-Armed Diazatrithia-15-Crown-5 and Diazatrithia-16-Crown-5 Ligands( )

1 edition published in 2001 in English and held by 1 WorldCat member library worldwide

The preliminary photophysical properties of a diazatrithia-15-crown-5 and diazatrithia-15-crown-5 ligands containing two 8-hydroxyquinoline side arms (15, 16,18 and 19) are reported. The studies show that ligands 16 and 19 exhibit increased fluorescence in the presence of Zn(2+) indicating that these ligands could be chemical sensors for Zn(2+)
 
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Associated Subjects
Organic chemistry Organic reaction animations Organic chemistry
Covers
Organic reaction animationsOrganic chemistry
Alternative Names
Savage, Poul B.

Languages
English (25)