Dokuyucu, Recep

Effect of colchicine on polycystic ovary syndrome: an experimental study by Ilay Ozturk Gozukara( )

1 edition published in 2015 in English and held by 2 WorldCat member libraries worldwide

Investigation of Therapeutic Effects of Erdosteine on Polycystic Ovary Syndrome in a Rat Model by Atilla Karateke( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Protective Effects of Intralipid and Caffeic Acid Phenethyl Ester (CAPE) on Hepatotoxicity and Pancreatic Injury Caused by Dichlorvos in Rats by Harun Alp( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

A novel tumor suppressor gene in basal cell carcinoma: inhibition of growth factor-2 by Metin Temel( )

1 edition published in 2015 in English and held by 2 WorldCat member libraries worldwide

The effect of Bongardia Chrysogonum on prostate tissue in a rat model of STZ-induced diabetes by Recep Dokuyucu( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

The Antipsychotic Effects of Omega-3 Fatty Acids in Rats( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Abstract: Background: In humans, omega-3 fatty acids are necessary for cell membranes, brain function and nerve transmission continuation. When animals are exposed to a new environment--or as a result of an apomorphine application that creates an agonistic effect on D1 and D2 receptors--they display behavioral reactions like rearing and stereotypy. This study aims to reveal the possible antipsychotic and oxidative effects of omega-3 fatty acids by comparing with chlorpromazine, a conventional antipsychotic drug, through evaluating the novelty-induced rearing and apomorphine-induced stereotypic behaviors, as well as malondialdehyde and glutathione levels in rats. Methods: Twenty-eight, adult, male, Wistar rats were used in the study. Briefly, 4 groups of rats (n = 7) were administered docosahexaenoic acid (DHA) + eicosapentaenoic acid (EPA) (300 mg/kg; DHA: 120 mg/kg + EPA: 180 mg/kg intraperitoneally [IP]), DHA + EPA (150 mg/kg; DHA: 60 mg/kg + EPA: 90 mg/kg IP), chlorpromazine (1 mg/kg, IP) and isotonic saline (1 mL/kg, IP). One hour later, apomorphine (2 mg/kg, subcutaneously) was administered to each rat. After the apomorphine administration, rats were observed for stereotypic behavior. Results: This study shows that omega-3 fatty acids, "similar to antipsychotics, " reversed the psychotic like effects, increase of oxidants and decrease of antioxidants that are composed experimentally in rats. Conclusions: The application of omega-3 fatty acids has antipsychotic effects and causes an oxidative imbalance. This study adds new evidence to the current literature regarding the possible antipsychotic effects of omega-3 fatty acids

Attenuating effects of caffeic acid phenethyl ester with intralipid on hepatotoxicity of chlorpyrifos in the case of rats = Łagodzące działanie estru fenetylowego kwasu kawowego z intralipidem na hepatotoksyczność chloropyrifosu u szczurów( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide