WorldCat Identities

Bataller, Ramon

Overview
Works: 22 works in 31 publications in 2 languages and 40 library holdings
Genres: Handbooks and manuals 
Roles: Contributor, Other, Author, Editor
Classifications: RC801, 616.3
Publication Timeline
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Most widely held works by Ramon Bataller
Regeneración hepática : mesa redonda by Maria Cascales Angosto( Book )

3 editions published in 2006 in Spanish and held by 4 WorldCat member libraries worldwide

Investigación de la función contráctil de las células estrelladas hepáticas : regulación por vasoconstrictores by Ramón Bataller Alberola( )

4 editions published between 2000 and 2001 in Spanish and held by 3 WorldCat member libraries worldwide

Manual clínico de gastroenterología y hepatología by Nicholas Joseph Talley( Book )

1 edition published in 2009 in English and held by 3 WorldCat member libraries worldwide

La obra se presenta como una obra de bolsillo multiautor que proporciona conceptos esenciales en gastroenterología y hepatología en un formato fácil y accesible y que se centra principalmente en los trastornos digestivos más comunes que se pueden presentar tanto en el contexto hospitalario como extrahospitalario. Precisamente, es este enfoque el que le convierte en un libro diferente a los clinical handbooks de otras especialidades. Así se encuentran capítulos dedicados específicamente a signos y síntomas comunes que conducen al paciente hasta la consulta (boca seca, dolor anal
Hepatic Stellate Cells as a Target for the Treatment of Liver Fibrosis( )

1 edition published in 2001 in English and held by 2 WorldCat member libraries worldwide

Liver Fibrosis in Alcoholic Liver Disease( )

1 edition published in 2015 in English and held by 2 WorldCat member libraries worldwide

Publisher Correction: Alcoholic liver disease by H. K Seitz( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Liver Fibrosis( )

1 edition published in 2015 in English and held by 2 WorldCat member libraries worldwide

Investigación de nuevas estrategias terapeúticas para la inflamación y la fibrosis hepática by Montserrat Moreno Sánchez( Book )

2 editions published in 2011 in Spanish and held by 2 WorldCat member libraries worldwide

Alcoholic hepatitis: should we combine old drugs for better results? by Joaquin Cabezas( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Hepatitis alcohólica estratificación pronóstica e identificación de mecanismos patogénicos by Marlene Domínguez García( Book )

2 editions published in 2009 in Spanish and held by 2 WorldCat member libraries worldwide

Cytokines and cytokine-receptors in the pathogenesis of alcoholic hepatitis by Silvia Affò( Book )

2 editions published in 2014 in English and held by 2 WorldCat member libraries worldwide

By performing a translational study we identified a specific pattern of genes differentially regulated in patients with severe alcoholic hepatitis (AH). A functional analysis of the gene expression profile showed several pathways deregulated in AH, including cytokines- cytokine receptor interaction. Within cytokine-cytokine receptor interaction pathway, Fn14 has been identified as the only receptor belonging to TNF superfamily to be exclusively up-regulated in patients with AH, and its expression has been shown to be associated with severity of the disease and mortality. We observed that Fn14 is upregulated in experimental models of progenitor cell expansion and co-expressed with Ep-CAM in livers of patients with AH, suggesting that Fn14 may regulate ductular reaction expansion. Moreover, we showed that Fn14 hepatic expression is regulated by ethanol and pro-fibrogenic factors, suggesting that alcohol abuse together with fibrogenic mediators may be directly responsible for the induction of Fn14 expression in ALD. Furthermore, transcriptome analysis identified CCL20 as the most up-regulated cytokine in the liver of patients with AH. Hepatic expression and serum levels of CCL20 have been found elevated in patients with AH and have been showed to be associated with key clinical features of the disease such as fibrosis, endotoxemia and short-term mortality. These data suggest that besides playing a role in AH pathogenesis, CCL20 may also be considered as a potential non-invasive biomarker. We found that CCL20 hepatic expression is up-regulated in acute, chronic and acute-on chronic experimental model of liver injury induced by carbon tetrachloride (CCl4) and lipopolysaccharide (LPS) and their combination, respectively. Macrophages and hepatic stellate cells have been identified as the main CCL20 producing cell types in experimental models of acute-on-chronic liver injury. Moreover, we have showed that CCL20 exerts pro-fibrogenic and pro-inflammatory and effects on primary human hepatic stellate cells and on macrophages, suggesting that CCL20 may participate in both hepatic fibrosis and inflammation during liver disease in an autocrine and paracrine manner. Finally, we have found that CCL20 mediates LPS-induced liver injury by promoting hepatocellular apoptosis, expression of pro-inflammatory and pro-fibrogenic mediators and by enhancing macrophages and neutrophils infiltrate recruitment. In conclusion, during this thesis we performed two studies leading to the identification of new potential targets for therapy in AH. The identification of Fn14 and CCL20 as new potential targets for therapy in AH and their correlations with key hallmarks of the disease such as ethanol consumption, fibrosis, progenitor cells expansion and endotoxemia underline the complexity of this disease and the crosstalk between many mediators that occurs in AH. The data presented in this thesis suggest that cytokines and cytokine-receptor pathway could represent a new potential target for therapy in ALD; and also provide new important insights and a useful resource for the study of the pathogenesis of this disease
New therapeutic targets in alcoholic hepatitis by Diana Arsene( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Hepatorenal Syndrome by Pere Ginès( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

Epigenetics in Liver Fibrosis( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

Alcoholic liver disease by H. K Seitz( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Nonalcoholic steatohepatitis (NASH)( Book )

1 edition published in 2007 in Spanish and held by 1 WorldCat member library worldwide

Expresión Génica Hepática en pacientes con hepatopatías crónicas : identificacación de dianas terapéuticas y evaluación de un tratamiento antifibrogénico by Jordi F Colmenero Arroyo( )

1 edition published in 2009 in Spanish and held by 1 WorldCat member library worldwide

Identification of novel molecular drivers of the pathogenesis of alcoholic hepatitis by Oriol Morales Ibañez( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Nonalcoholic steatohepatitis( Book )

1 edition published in 2007 in English and held by 1 WorldCat member library worldwide

El sistema del citocromo p450 : bases químicas y aplicaciones en la práctica médica by Ramón Bataller Alberola( Book )

2 editions published in 1998 in Spanish and held by 1 WorldCat member library worldwide

 
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Audience Level
0
Audience Level
1
  Kids General Special  
Audience level: 0.94 (from 0.70 for Manual cli ... to 0.99 for El sistema ...)

Associated Subjects
Alternative Names
Bataller Alberola, Ramón

Bataller, Ramón

Languages
Spanish (15)

English (14)