WorldCat Identities

Porcher, Jean-Marc

Overview
Works: 19 works in 21 publications in 2 languages and 35 library holdings
Roles: Contributor, Opponent, Thesis advisor, Author, Other
Publication Timeline
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Most widely held works by Jean-Marc Porcher
ETUDE EN CULTURE DE CELLULES DU METABOLISME ET DE LA TOXICITE DE LA T-2 TOXINE : INFORMATISATION D'UN TEST DE CYTOTOXICITE by Jean-Marc Porcher( Book )

2 editions published in 1988 in French and held by 3 WorldCat member libraries worldwide

A potential biomarker of androgen exposure in European bullhead (Cottus sp.) kidney by Mélanie Villeret( )

1 edition published in 2012 in English and held by 2 WorldCat member libraries worldwide

In situ experiments to assess effects of constraints linked to caging on ecotoxicity biomarkers of the three-spined stickleback (Gasterosteus aculeatus L.) by Antoine Le Guernic( )

1 edition published in 2015 in English and held by 2 WorldCat member libraries worldwide

Erythrocyte antioxidant enzyme activities in coal miners from three French regions by Rachel Perrin-Nadif( )

1 edition published in 1998 in English and held by 2 WorldCat member libraries worldwide

Approche multi- biomarqueurs chez l'épinoche à trois épines (Gasterosteus aculeatus L.) : un modèle pour la surveillance des écosystèmes aquatiques continentaux by Wilfried Sanchez( Book )

2 editions published in 2007 in French and held by 2 WorldCat member libraries worldwide

The aim of this work was to characterise the usefullness of three-spined stickleback (Gasterosteus aculeatus L.) as a sentinel fish species to assess aquatic environment contamination using a set of biomarkers. For this purpose, assays for biomarkers of xenobiotic metabolisation, oxidative stress, neurotoxicity and estrogenic or androgenic endocrine disruption have been developed and validated. Our laboratory and field results show that investigated biomarkers are sensitive and inducible parameters. To run the full potential of biomarkers, basal values mesured in reference site are established and their seasonal or gender variability is characterised. Field application provides information on early effects of contamination. Moreover, it provides complementary informations compared to chemical analysis and populational investigations and allows sampling site discrimination. At least, the development of a biomarker-based index allows the synthesis of collected data and offers a perspective for using biomarkers in aquatic ecosystem management
Acclimation capacity of the three-spined stickleback (Gasterosteus aculeatus, L.) to a sudden biological stress following a polymetallic exposure by Antoine Le Guernic( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Distribution of steroid- and dioxin-like activities between sediments, POCIS and SPMD in a French river subject to mixed pressures by Nicolas Creusot( )

1 edition published in 2013 in English and held by 2 WorldCat member libraries worldwide

Determination of a new index of sexual maturity (ISM) in zebra mussel using flow cytometry: interest in ecotoxicology by Gabrielle Magniez( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

In situ effects of metal contamination from former uranium mining sites on the health of the three-spined stickleback (Gasterosteus aculeatus, L.) by Antoine Le Guernic( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Evaluation of an hPXR reporter gene assay for the detection of aquatic emerging pollutants: screening of chemicals and application to water samples by Nicolas Creusot( )

1 edition published in 2009 in English and held by 2 WorldCat member libraries worldwide

Effect-directed analysis of endocrine-disrupting compounds in multi-contaminated sediment: identification of novel ligands of estrogen and pregnane X receptors by Nicolas Creusot( )

1 edition published in 2013 in English and held by 2 WorldCat member libraries worldwide

Impact of confinement and food access restriction on the three-spined stickleback (Gasterosteus aculeatus, L.) during caging: a multi-biomarker approach by Audrey Catteau( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Le chabot comme espèce modèle pour la mise en oeuvre d'une approche multi-biomarqueurs : interêt de l'immuno-écotoxicologie by Sabrina Jolly( )

1 edition published in 2011 in French and held by 1 WorldCat member library worldwide

Pertinence d'une approche multibiomarqueurs en biosurveillance active avec l'épinoche à trois épines (Gasterosteus aculeatus) by Audrey Catteau( )

1 edition published in 2019 in French and held by 1 WorldCat member library worldwide

Many chemical contaminants have been produced and spread into aquatic environments and given rise to anthropogenic activities. In order to assess and predict the impacts of this contamination on organisms and ecosystems, several tools were developed. Among them, biomarkers have been shown to be sensible and early indicators of a perturbation at sub individual level. These physiological responses can be measured in native individuals as well as in individuals from husbandry imported on the field through caging systems. This latter approach, mostly known as active biomonitoring approach, brings with it the ability to overcome some confounding factors present when native individuals are used (history, exposure time, adaptation mechanism). Additionally, the use of imported individuals enables the study of sites in which the model species is endangered or absent. This active methodology also seems more effective in defining reference levels for the comparison of sites over large geographic scales. In this context, the present work aims to assess the relevance of using a new model species in active biomonitoring approach: the three spined stickleback (Gasterosteus aculeatus). Several physiological functions have been chosen to be representative of the global health of individuals (antioxidant system and oxidative damages, biotransformation enzymes, reproduction system, innate immune system, synaptic transmission). As a first step, the effect of a restricted access to food and the confinement induced by caging conditions have been characterized in two seasons with the aim to ensure a correct and thorough interpretation of the results. Then, the approach has been deployed on the field (i) to assess the efficiency of a constructed wetland built downstream a wastewater treatment plant (WWTP), (ii) to assess the potential effects of several effluents of WWTP and (ii) to discriminate different sites along the Meuse basin (Interreg DIADeM program). Findings have been encouraging in highlighting the relevance of the three spined stickleback as a sentinel species and the selected biomarkers in this context of contamination in active biomonitoring. In a larger scale, these same tools have made it possible to discriminate the different sites in the Meuse basin according to the modulated physiological functions. Thus, this work has demonstrated the potential of the multibiomarker approach in active biomonitoring with the three spined stickleback in the assessment and the characterization of water quality
Pertinence écologique des biomarqueurs d'immunotoxicité en surveillance environnementale by Adrien Marchand( )

1 edition published in 2018 in French and held by 1 WorldCat member library worldwide

The natural variability of cellular innate immunomarkers in a model species in ecotoxicology, the three-spined stickleback, Gasterosteus aculeatus was studied in order to determine immunomarker reference values useful for passive biomonitoring Thus, effects of three confounding factors, sampling period, sex, and fish body size, were investigated in controlled laboratory conditions. This first phase enabled the construction of a mathematical model that predicts immunomarker mean values in function of the three considered confounding factors, along with a range of reference values in laboratory conditions. To be used for biomonitoring, it is important to know if the laboratory model is correctly predicting other conditions. Therefore, laboratory reference ranges were compared to data obtained from fish sampled in semi-natural conditions (mesocosm conditions) and fish sampled in natural conditions, in one uncontaminated site (field condition). Results of this comparison allowed to construct a predictive model of the natural variations of immunomarker values in each experimental condition. Tested in a biomonitoring context, the use of field reference range allowed to i) discriminate between contaminated and uncontaminated sites and ii) identify false positives that are due to the morphological heterogeneity of fish sampled in the different sites
Étude des paramètres digestifs chez l'épinoche à trois épines (Gasterosteus aculeatus) : intérêt en tant que biomarqueurs. by Younes Hani( )

1 edition published in 2018 in French and held by 1 WorldCat member library worldwide

In a large context of global warming (temperature increase), anthropogenic activities introduce significant amounts of organic and inorganic pollutants causing chemical and physical disruption on the aquatic ecosystems and there living organisms. This work is therefore part of a context that covers both the need for the development of new tools for assessing the quality of aquatic environments, as required by regulations such as the DCE, and the provision of new knowledge on multistress effects on living organisms. Specifically, we examined different energy metabolism parameters and their interest as novel biomarkers in the threespine stickleback (Gasterosteus aculeatus), a model species in ecotoxicology. This thesis aims to: (i) characterize the influence of biotic and abiotic parameters on the chosen parameters, (ii) to specify the response pattern of digestive enzymes in a multistress context (chronic exposure to a very low concentration of cadmium and / or thermal stress), and (iii) to study the consequences of this multiple exposure on sticklebacks' reproduction, in relation with the modulation of the energy parameters. Results show that temperature is the major stress factor with negative effects on most of the studied parameters (i.e. growth parameters, some parameters of energy metabolism, oxidative stress parameters and parents' reproduction parameters). Concerning cadmium, this chemical stress had effects at the molecular level (digestive enzymes) but did not affect the reproductive parameters of adult fish. However, consequences of cadmium exposure are nevertheless observed on the offspring (survival capacity). The negative impact of the double stress sticklebacks' reproduction may be due to an altered parental investment, which probably followed an alteration of one of the parameters in relation to energy acquisition, such as digestive enzymes. Thus, the parameters associated with energy metabolism, and especially with the acquisition of energy (digestion), show an interesting sensitivity to the different stresses studied, highlighting their potential as new biomarkers
 
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Audience level: 0.94 (from 0.78 for ETUDE EN C ... to 0.97 for Approche m ...)

WorldCat IdentitiesRelated Identities
Alternative Names
Jean-Marc Porcher wetenschapper

Languages
English (13)

French (8)